Protein expression in Pichia pastoris: Recent achievements and perspectives for heterologous protein production

Applied Microbiology and Biotechnology

Volumn 98, Issue 12, 2014, Pages 5301-5317

  Ahmad, Mudassar ^a   Hirz, Melanie ^a   Pichler, Harald ^a,b   Schwab, Helmut ^a,b  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^b AUSTRIAN CENTRE OF INDUSTRIAL BIOTECHNOLOGY   (Austria)

Author keywords

Chaperone; Pichia pastoris; Protease deficient strains; Protein expression; Protein secretion; Yeast

Indexed keywords

BIOLOGICAL MEMBRANES; STRAIN; YEAST;

CHAPERONE; COMMERCIAL APPLICATIONS; HETEROLOGOUS PROTEIN PRODUCTION; MEMBRANE PROTEIN EXPRESSIONS; PICHIA PASTORIS; PROTEIN EXPRESSIONS; PROTEIN SECRETION; PROTEOLYTIC DEGRADATION;

PROTEINS;

ALCOHOL DEHYDROGENASE; ALCOHOL OXIDASE; ENOLASE; FORMALDEHYDE DEHYDROGENASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCEROL KINASE; ISOCITRATE LYASE; PHOSPHOGLYCERATE KINASE; RECOMBINANT PROTEIN;

BIOENGINEERING; DRUG; ENZYME ACTIVITY; GENE EXPRESSION; PROTEIN; SECRETION; YEAST;

AUXOTROPHY; EXPRESSION VECTOR; FUNGAL GENOME; FUNGAL STRAIN; MOLECULAR CLONING; NONHUMAN; PICHIA PASTORIS; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN SECRETION; REVIEW; GENE EXPRESSION; GENETICS; METABOLISM; MICROBIOLOGY; PICHIA;

PICHIA PASTORIS;

GENE EXPRESSION; INDUSTRIAL MICROBIOLOGY; PICHIA; RECOMBINANT PROTEINS;

EID: 84903814380     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-014-5732-5     Document Type: Review

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