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Volumn 15, Issue 7, 1999, Pages 563-572

Disruption of the KEX1 gene in Pichia pastoris allows expression of full-length murine and human endostatin

Author keywords

Endostatin; KEX1 disruption; Pichia pastoris

Indexed keywords

ANGIOGENESIS INHIBITOR; ENDOSTATIN; RECOMBINANT PROTEIN;

EID: 0032946129     PISSN: 0749503X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0061(199905)15:7<563::AID-YEA398>3.0.CO;2-R     Document Type: Article
Times cited : (60)

References (16)
  • 1
    • 0031469819 scopus 로고    scopus 로고
    • Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance
    • Boehm, T., Folkman, J., Browder, T. and O'Reilly, M. S. (1997). Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature 390, 404-407.
    • (1997) Nature , vol.390 , pp. 404-407
    • Boehm, T.1    Folkman, J.2    Browder, T.3    O'Reilly, M.S.4
  • 3
    • 0026094226 scopus 로고
    • Production of mouse epidermal growth factor in yeast: High level secretion using Pichia pastoris strains containing multiple gene copies
    • Clare, J. J., Romanos, M. A., Rayment, F. B., Rowedder, J. E., Smith, M. A., Payne, M. M., Sreekrishna, K. and Henwood, C. A. (1991). Production of mouse epidermal growth factor in yeast: high level secretion using Pichia pastoris strains containing multiple gene copies. Gene 105, 205-212.
    • (1991) Gene , vol.105 , pp. 205-212
    • Clare, J.J.1    Romanos, M.A.2    Rayment, F.B.3    Rowedder, J.E.4    Smith, M.A.5    Payne, M.M.6    Sreekrishna, K.7    Henwood, C.A.8
  • 4
    • 0023653256 scopus 로고
    • Yeast KEX1 gene encodes a putative protease with a carboxypeptidase B-like function involved in killer toxin and α-factor precursor processing
    • Dmochowska, A., Dignard, D., Henning, D., Thomas, D. Y. and Bussey, H. (1987). Yeast KEX1 gene encodes a putative protease with a carboxypeptidase B-like function involved in killer toxin and α-factor precursor processing. Cell 50, 573-584.
    • (1987) Cell , vol.50 , pp. 573-584
    • Dmochowska, A.1    Dignard, D.2    Henning, D.3    Thomas, D.Y.4    Bussey, H.5
  • 5
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman, J. (1971). Tumor angiogenesis: therapeutic implications. N. Engl. J. Med. 285, 1182-1186.
    • (1971) N. Engl. J. Med. , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 6
    • 0028152841 scopus 로고
    • C-terminal proteolytic degradation of recombinant desulphato-hirudin and its mutants in the yeast Saccharomyces cerevisiae
    • Heim, J., Takabayashi, K., Meyhack, B. and Pohlig, G. (1994). C-terminal proteolytic degradation of recombinant desulphato-hirudin and its mutants in the yeast Saccharomyces cerevisiae. Eur. J. Biochem. 226, 341-353.
    • (1994) Eur. J. Biochem. , vol.226 , pp. 341-353
    • Heim, J.1    Takabayashi, K.2    Meyhack, B.3    Pohlig, G.4
  • 7
    • 0028081167 scopus 로고
    • High-level secretion and very efficient isotopic labeling of tick anticoagulant peptide (TAP) expressed in the methylotrophic yeast, Pichia pastoris
    • Laroche, Y., Storme, V., Meutter, J. D., Messens, J. and Lauwereys, M. (1994). High-level secretion and very efficient isotopic labeling of tick anticoagulant peptide (TAP) expressed in the methylotrophic yeast, Pichia pastoris. Bio/Technology 12, 1119-1124.
    • (1994) Bio/Technology , vol.12 , pp. 1119-1124
    • Laroche, Y.1    Storme, V.2    Meutter, J.D.3    Messens, J.4    Lauwereys, M.5
  • 8
    • 0029671196 scopus 로고    scopus 로고
    • Cloning and characterization of the Pichia pastoris PRC1 gene encoding carboxypeptidase Y
    • Ohi, H., Ohtani, W., Okazaki, N., Furuhata, N. and Ohmura, T. (1996). Cloning and characterization of the Pichia pastoris PRC1 gene encoding carboxypeptidase Y. Yeast 12, 31-40.
    • (1996) Yeast , vol.12 , pp. 31-40
    • Ohi, H.1    Ohtani, W.2    Okazaki, N.3    Furuhata, N.4    Ohmura, T.5
  • 10
    • 0029944122 scopus 로고    scopus 로고
    • Angiostatin induces and sustains dormancy of human primary tumours in mice
    • O'Reilly, M. S., Holmgren, L., Chen, C. and Folkman, J. (1996). Angiostatin induces and sustains dormancy of human primary tumours in mice. Nature Med. 2, 689-692.
    • (1996) Nature Med. , vol.2 , pp. 689-692
    • O'Reilly, M.S.1    Holmgren, L.2    Chen, C.3    Folkman, J.4
  • 13
    • 0026778048 scopus 로고
    • Foreign gene expression in yeast: A review
    • Romanos, M. A., Scorer, C. A. and Clare, J. J. (1992). Foreign gene expression in yeast: a review. Yeast 8, 423-488.
    • (1992) Yeast , vol.8 , pp. 423-488
    • Romanos, M.A.1    Scorer, C.A.2    Clare, J.J.3
  • 14
    • 0030610593 scopus 로고    scopus 로고
    • Crystal structure of KEX1Δp, a prohormone-processing carboxypeptidase from Saccharomyces cerevisiae
    • Shilton, B. H., Thomas, D. Y. and Cygler, M. (1997). Crystal structure of KEX1Δp, a prohormone-processing carboxypeptidase from Saccharomyces cerevisiae. Biochemistry 36, 9002-9012.
    • (1997) Biochemistry , vol.36 , pp. 9002-9012
    • Shilton, B.H.1    Thomas, D.Y.2    Cygler, M.3
  • 15
    • 0023690624 scopus 로고
    • Basic carboxypeptidases: Regulator of peptide hormone activity
    • Skidgel, R. A. (1988). Basic carboxypeptidases: regulator of peptide hormone activity. Trends Pharmacol. Sci. 9, 299-304.
    • (1988) Trends Pharmacol. Sci. , vol.9 , pp. 299-304
    • Skidgel, R.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.