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Volumn 389, Issue , 2007, Pages 11-25

Vectors and strains for expression

Author keywords

Expression strains; Expression vectors; Heterologous protein expression in Pichia pastoris; Plasmids

Indexed keywords

ARTICLE; FUNGAL GENOME; GENE EXPRESSION; GENE VECTOR; GENETICS; PICHIA;

EID: 36549052077     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1385/1-59745-456-7:11     Document Type: Article
Times cited : (25)

References (42)
  • 1
    • 36549014932 scopus 로고    scopus 로고
    • Keck Graduate Institute, Faculty and Research, Resources, Last accessed May 8
    • Keck Graduate Institute, Faculty and Research, James M. Cregg, Resources. http://faculty.kgi.edu/cregg/index.htm. Last accessed May 8, 2007.
    • (2007) Cregg
    • James, M.1
  • 2
    • 0035941468 scopus 로고    scopus 로고
    • New selectable marker/auxotrophic host strain combinations for molecular genetic manipulation of Pichia pastoris
    • Lin Cereghino, G. P., Lin Cereghino, J., Sunga, A. J., et al. (2001) New selectable marker/auxotrophic host strain combinations for molecular genetic manipulation of Pichia pastoris. Gene 263, 159-169.
    • (2001) Gene , vol.263 , pp. 159-169
    • Lin Cereghino, G.P.1    Lin Cereghino, J.2    Sunga, A.J.3
  • 3
    • 0344466719 scopus 로고    scopus 로고
    • Cloning and disruption of the PpURA5 gene and construction of a set of integration vectors for the stable genetic modification of Pichia pastoris
    • Nett, J. H. and Gerngross, T. U. (2003) Cloning and disruption of the PpURA5 gene and construction of a set of integration vectors for the stable genetic modification of Pichia pastoris. Yeast 20, 1279-1290.
    • (2003) Yeast , vol.20 , pp. 1279-1290
    • Nett, J.H.1    Gerngross, T.U.2
  • 4
    • 1842839988 scopus 로고    scopus 로고
    • The Pichia pastoris formaldehyde dehydrogenase gene (FLD1) as a marker for selection of multicopy expression strains of P. pastoris
    • Sunga, A. J. and Cregg, J. M. (2004) The Pichia pastoris formaldehyde dehydrogenase gene (FLD1) as a marker for selection of multicopy expression strains of P. pastoris. Gene 330, 39-47.
    • (2004) Gene , vol.330 , pp. 39-47
    • Sunga, A.J.1    Cregg, J.M.2
  • 5
    • 32044443408 scopus 로고    scopus 로고
    • Overproduction of Pichia pastoris or Plasmodium falciparum protein disulfide isomerase affects expression, folding and O-linked glycosylation of a malaria vaccine candidate expressed in P. pastoris
    • Tsai, C. W., Duggan, P. F., Shimp, R. L., Miller, L. H., and Narum, D. L. (2006) Overproduction of Pichia pastoris or Plasmodium falciparum protein disulfide isomerase affects expression, folding and O-linked glycosylation of a malaria vaccine candidate expressed in P. pastoris. J. Biotechnol. 121, 458-470.
    • (2006) J. Biotechnol , vol.121 , pp. 458-470
    • Tsai, C.W.1    Duggan, P.F.2    Shimp, R.L.3    Miller, L.H.4    Narum, D.L.5
  • 6
    • 0035902922 scopus 로고    scopus 로고
    • Use of HDEL-tagged Trichoderma reesei mannosyl oligosaccharide 1,2-alpha-D-mannosidase for N-glycan engineering in Pichia pastoris
    • Callewaert, N., Laroy, W., Cadirgi, H., et al. (2001) Use of HDEL-tagged Trichoderma reesei mannosyl oligosaccharide 1,2-alpha-D-mannosidase for N-glycan engineering in Pichia pastoris. FEBS Letters 503, 173-178.
    • (2001) FEBS Letters , vol.503 , pp. 173-178
    • Callewaert, N.1    Laroy, W.2    Cadirgi, H.3
  • 7
    • 4444231014 scopus 로고    scopus 로고
    • Engineering of an artificial glycosylation pathway blocked in core oligosaccharide assembly in the yeast Pichia pastoris: Production of complex humanized glycoproteins with terminal galactose
    • Bobrowicz, P., Davidson, R. C., Li, H., et al. (2004) Engineering of an artificial glycosylation pathway blocked in core oligosaccharide assembly in the yeast Pichia pastoris: production of complex humanized glycoproteins with terminal galactose. Glycobiology 14, 757-766.
    • (2004) Glycobiology , vol.14 , pp. 757-766
    • Bobrowicz, P.1    Davidson, R.C.2    Li, H.3
  • 8
    • 0038753800 scopus 로고    scopus 로고
    • Use of combinatorial genetic libraries to humanize N-linked glycosylation in the yeast Pichia pastoris
    • Choi, B. K., Bobrowicz, P., Davidson, R. C., et al. (2003) Use of combinatorial genetic libraries to humanize N-linked glycosylation in the yeast Pichia pastoris. Proc. Natl. Acad. Sci. 100, 5022-5027.
    • (2003) Proc. Natl. Acad. Sci , vol.100 , pp. 5022-5027
    • Choi, B.K.1    Bobrowicz, P.2    Davidson, R.C.3
  • 9
    • 0042322600 scopus 로고    scopus 로고
    • Production of complex human glycoproteins in yeast
    • Hamilton, S. R., Bobrowicz, P., Bobrowica, B., et al. (2003) Production of complex human glycoproteins in yeast. Science 301, 1244-1246.
    • (2003) Science , vol.301 , pp. 1244-1246
    • Hamilton, S.R.1    Bobrowicz, P.2    Bobrowica, B.3
  • 10
    • 0032541478 scopus 로고    scopus 로고
    • A strong nitrogen source-regulated promoter for controlled expression of foreign genes in the yeast Pichia pastoris
    • Shen, S., Suiter, G., Jeffries, T. W., and Cregg, J. M. (1998) A strong nitrogen source-regulated promoter for controlled expression of foreign genes in the yeast Pichia pastoris. Gene 216, 93-102.
    • (1998) Gene , vol.216 , pp. 93-102
    • Shen, S.1    Suiter, G.2    Jeffries, T.W.3    Cregg, J.M.4
  • 11
    • 0031239815 scopus 로고    scopus 로고
    • Recombinant protein expression in an alcohol oxidase-defective strain of Pichia pastoris in feedbatch fermentations. Enzyme Microbiol Technol
    • Chiruvolu, V., Cregg, J. M., and Meagher, M. M. (1997) Recombinant protein expression in an alcohol oxidase-defective strain of Pichia pastoris in feedbatch fermentations. Enzyme Microbiol Technol. Enzyme Microb. Technol. 21, 277-283.
    • (1997) Enzyme Microb. Technol , vol.21 , pp. 277-283
    • Chiruvolu, V.1    Cregg, J.M.2    Meagher, M.M.3
  • 12
    • 0023234256 scopus 로고
    • High level expression and efficient assembly of hepatitis B surface antigen in the methylotrophic yeast
    • Cregg, J. M., Tschopp, J. F., Stillman, C., et al. (1987) High level expression and efficient assembly of hepatitis B surface antigen in the methylotrophic yeast, Pichia pastoris. Bio/Technology 5, 479-485.
    • (1987) Pichia pastoris. Bio/Technology , vol.5 , pp. 479-485
    • Cregg, J.M.1    Tschopp, J.F.2    Stillman, C.3
  • 14
    • 0023547875 scopus 로고
    • Development of yeast transformation systems and construction of methanol-utilization-defective mutants of Pichia pastoris by gene disruption, in)
    • Stewart, G. G, Russell, I, Klein, R. D. and Hiebsch, R. R, eds, CRC Press, Boca Raton, FL, pp
    • Cregg, J. M. and Madden, K. R. (1987) Development of yeast transformation systems and construction of methanol-utilization-defective mutants of Pichia pastoris by gene disruption, in). Biological Research on Industrial Yeasts (Stewart, G. G., Russell, I., Klein, R. D. and Hiebsch, R. R., eds.), CRC Press, Boca Raton, FL, pp. 1-18.
    • (1987) Biological Research on Industrial Yeasts , pp. 1-18
    • Cregg, J.M.1    Madden, K.R.2
  • 15
    • 0024636430 scopus 로고
    • Functional characterization of the two alcohol oxidase genes from the yeast Pichia pastoris
    • Cregg, J. M., Madden, K. R., Barringer, K. J., Thill, G. P., and Stillman, C. A. (1989) Functional characterization of the two alcohol oxidase genes from the yeast Pichia pastoris. Mol. Cell. Biol. 9, 1316-1323.
    • (1989) Mol. Cell. Biol , vol.9 , pp. 1316-1323
    • Cregg, J.M.1    Madden, K.R.2    Barringer, K.J.3    Thill, G.P.4    Stillman, C.A.5
  • 16
    • 0031604266 scopus 로고    scopus 로고
    • Secretion of recombinant human insulin-like growth factor I (IGF-I)
    • Brierley, R. A. (1998) Secretion of recombinant human insulin-like growth factor I (IGF-I). Methods Mol. Biol. 103, 149-177.
    • (1998) Methods Mol. Biol , vol.103 , pp. 149-177
    • Brierley, R.A.1
  • 17
    • 0029586382 scopus 로고
    • Large scale expression, purification and characterization of the smallest active fragment of thrombomodulin: The roles of the sixth domain and of methionine-388
    • White, C. E., Hunter, M. J., Meininger, D. P., White, L. R., and Komives, E. A. (1995) Large scale expression, purification and characterization of the smallest active fragment of thrombomodulin: the roles of the sixth domain and of methionine-388. Protein Eng. 8, 1177-1187.
    • (1995) Protein Eng , vol.8 , pp. 1177-1187
    • White, C.E.1    Hunter, M.J.2    Meininger, D.P.3    White, L.R.4    Komives, E.A.5
  • 18
    • 0032946129 scopus 로고    scopus 로고
    • Disruption of the KEX1 gene in Pichia pastoris allows expression of full-length murine and human endostatin
    • Boehm, T., Pirie-Shepard, S., Trinh, L. B., Shiloach, J., and Folkman, J. (1999) Disruption of the KEX1 gene in Pichia pastoris allows expression of full-length murine and human endostatin. Yeast 15, 563-567.
    • (1999) Yeast , vol.15 , pp. 563-567
    • Boehm, T.1    Pirie-Shepard, S.2    Trinh, L.B.3    Shiloach, J.4    Folkman, J.5
  • 19
    • 0032211383 scopus 로고    scopus 로고
    • Variation in N-linked oligosaccharide structures on heterologous proteins secreted by the methylotrophic yeast Pichia pastoris
    • Montesino, R., Garcia, R., Qunitero, O., and Cremata, J. A. (1998) Variation in N-linked oligosaccharide structures on heterologous proteins secreted by the methylotrophic yeast Pichia pastoris. Protein Expr. Purif 14, 197-207.
    • (1998) Protein Expr. Purif , vol.14 , pp. 197-207
    • Montesino, R.1    Garcia, R.2    Qunitero, O.3    Cremata, J.A.4
  • 20
    • 0028863435 scopus 로고
    • Mannosyltransferase activities in membranes from various yeast strains
    • Verostek, M. F. and Trimble, R. B. (1995) Mannosyltransferase activities in membranes from various yeast strains. Glycobiology 5, 671-681.
    • (1995) Glycobiology , vol.5 , pp. 671-681
    • Verostek, M.F.1    Trimble, R.B.2
  • 21
    • 0026778048 scopus 로고
    • Foreign gene expression in yeast: A review
    • Romanos, M. A., Scorer, C. A., and Clare, J. J. (1992) Foreign gene expression in yeast: a review. Yeast 8, 423-488.
    • (1992) Yeast , vol.8 , pp. 423-488
    • Romanos, M.A.1    Scorer, C.A.2    Clare, J.J.3
  • 22
    • 0021983928 scopus 로고
    • Isolation of alcohol oxidase and two other methanol regulatable genes from the yeast Pichia pastoris
    • Ellis, S. B., Brust, P. F., Koutz, P. J., Waters, A. F., Harpold, M. M., and Gingeras, T. R. (1985) Isolation of alcohol oxidase and two other methanol regulatable genes from the yeast Pichia pastoris. Mol. Cell. Biol. 5, 1111-1121.
    • (1985) Mol. Cell. Biol , vol.5 , pp. 1111-1121
    • Ellis, S.B.1    Brust, P.F.2    Koutz, P.J.3    Waters, A.F.4    Harpold, M.M.5    Gingeras, T.R.6
  • 23
    • 0033955337 scopus 로고    scopus 로고
    • Heterologous protein expression in the methylotrophic yeast Pichia pastoris
    • Lin Cereghino, J. and Cregg, J. M. (2001) Heterologous protein expression in the methylotrophic yeast Pichia pastoris. FEMS Microbiology Reviews 24, 45-66.
    • (2001) FEMS Microbiology Reviews , vol.24 , pp. 45-66
    • Lin Cereghino, J.1    Cregg, J.M.2
  • 24
    • 0028955340 scopus 로고
    • PER3, a gene required for peroxisome biogenesis in Pichia pastoris, encodes a peroxisomal membrane protein involved in protein import
    • Liu, H., Tan, X., Russell, K. A., Veenhuis, M., and Cregg, J. M. (1995) PER3, a gene required for peroxisome biogenesis in Pichia pastoris, encodes a peroxisomal membrane protein involved in protein import. J. Biol.Chem. 270, 10,940-10,951.
    • (1995) J. Biol.Chem , vol.270
    • Liu, H.1    Tan, X.2    Russell, K.A.3    Veenhuis, M.4    Cregg, J.M.5
  • 25
    • 0032526934 scopus 로고    scopus 로고
    • A versatile set of vectors for constitutive and regulated gene expression in Pichia pastoris
    • Sears, I. B., O'Connor, J., Rossanese, O. W., and Glick, B. S. (1998) A versatile set of vectors for constitutive and regulated gene expression in Pichia pastoris. Yeast 14, 783-790.
    • (1998) Yeast , vol.14 , pp. 783-790
    • Sears, I.B.1    O'Connor, J.2    Rossanese, O.W.3    Glick, B.S.4
  • 26
    • 0031579445 scopus 로고    scopus 로고
    • Isolation of the Pichia pastoris glyceraldehyde-3-phosphate dehydrogenase gene and regulation and use of its promoter
    • Waterham, H. R., Digan, M. E., Koutz, P. J., Lair, S. V., and Cregg, J. M. (1997) Isolation of the Pichia pastoris glyceraldehyde-3-phosphate dehydrogenase gene and regulation and use of its promoter. Gene 186, 37-44.
    • (1997) Gene , vol.186 , pp. 37-44
    • Waterham, H.R.1    Digan, M.E.2    Koutz, P.J.3    Lair, S.V.4    Cregg, J.M.5
  • 27
    • 0033214215 scopus 로고    scopus 로고
    • Functional phytohemagglutinin (PHA) and Galanthus nivalis agglutinin (GNA) expressed in Pichia pastoris correct N-terminal processing and secretion of heterologous proteins expressed using the PHA-E signal peptide
    • Raemaeker, R. J. M., deMuro, L., Gatehouse, J. A., and Fordham-Skelton, A. P. (1999) Functional phytohemagglutinin (PHA) and Galanthus nivalis agglutinin (GNA) expressed in Pichia pastoris correct N-terminal processing and secretion of heterologous proteins expressed using the PHA-E signal peptide. Eur. J. Biochem. 65, 394-403.
    • (1999) Eur. J. Biochem , vol.65 , pp. 394-403
    • Raemaeker, R.J.M.1    deMuro, L.2    Gatehouse, J.A.3    Fordham-Skelton, A.P.4
  • 28
    • 0033043522 scopus 로고    scopus 로고
    • Secretory expression and characterization of insulin in Pichia pastoris
    • Kjeldsen, T., Pettersson, A. F., and Hatch, M. (1999) Secretory expression and characterization of insulin in Pichia pastoris. Biotechnol. Appl. Biochem. 29, 79-86.
    • (1999) Biotechnol. Appl. Biochem , vol.29 , pp. 79-86
    • Kjeldsen, T.1    Pettersson, A.F.2    Hatch, M.3
  • 29
    • 0032053012 scopus 로고    scopus 로고
    • Secretion of recombinant pro- and mature fungal alpha-sarcin ribotoxin by the methylotrophic yeast Pichia pastoris: The Lys-Arg motif is required for maturation
    • Martinez-Ruiz, A., Martinez del Pozo, A., Lacadena, J., et al. (1998) Secretion of recombinant pro- and mature fungal alpha-sarcin ribotoxin by the methylotrophic yeast Pichia pastoris: the Lys-Arg motif is required for maturation. Protein Expr. Purif. 12, 315-322.
    • (1998) Protein Expr. Purif , vol.12 , pp. 315-322
    • Martinez-Ruiz, A.1    Martinez del Pozo, A.2    Lacadena, J.3
  • 30
    • 0031777548 scopus 로고    scopus 로고
    • Design, total synthesis, and functional overexpression of the Candida rugosa lip1 gene coding for a major industrial lipase
    • Brocea, S., Schmidt-Dannert, C., Lotti, M., Alberghina, L., and Schmid, R. D. (1998) Design, total synthesis, and functional overexpression of the Candida rugosa lip1 gene coding for a major industrial lipase. Protein Sci. 7, 1415-1422.
    • (1998) Protein Sci , vol.7 , pp. 1415-1422
    • Brocea, S.1    Schmidt-Dannert, C.2    Lotti, M.3    Alberghina, L.4    Schmid, R.D.5
  • 32
    • 0028072097 scopus 로고
    • Blasticidin S deaminase gene from Aspergillus terreus (BSD): A new drug resistance gene for transfection of mammalian cells
    • Kimura, M., Takatsuki, A., and Yamaguchi, I. (1994) Blasticidin S deaminase gene from Aspergillus terreus (BSD): a new drug resistance gene for transfection of mammalian cells. Biochim. Biophys. ACTA 1219, 653-659.
    • (1994) Biochim. Biophys. ACTA , vol.1219 , pp. 653-659
    • Kimura, M.1    Takatsuki, A.2    Yamaguchi, I.3
  • 33
    • 0026047364 scopus 로고
    • Recombinant Bordetella pertussis pertactin (P69) from the yeast Pichia pastoris: High-level production and immunological properties
    • Romanos, M. A., Clare, J. J., Beesley, K. M., et al. (1991) Recombinant Bordetella pertussis pertactin (P69) from the yeast Pichia pastoris: high-level production and immunological properties. Vaccine 9, 901-906.
    • (1991) Vaccine , vol.9 , pp. 901-906
    • Romanos, M.A.1    Clare, J.J.2    Beesley, K.M.3
  • 34
    • 14744271884 scopus 로고
    • High-level expression of tetanus toxin fragment C in Pichia pastoris strains containing multiple tandem integrations of the gene
    • Clare, J. J., Rayment, F. B., Ballantine, S. P., Sreekrishna, K., and Romanos, M. A. (1991) High-level expression of tetanus toxin fragment C in Pichia pastoris strains containing multiple tandem integrations of the gene. Bio/Technol 9, 455-460.
    • (1991) Bio/Technol , vol.9 , pp. 455-460
    • Clare, J.J.1    Rayment, F.B.2    Ballantine, S.P.3    Sreekrishna, K.4    Romanos, M.A.5
  • 35
    • 0029821364 scopus 로고    scopus 로고
    • Antibody screening for secreted proteins expressed in Pichia pastoris
    • Wung, J. L. and Gascoigne, N. R. (1996) Antibody screening for secreted proteins expressed in Pichia pastoris. BioTechniques 21, 808-812.
    • (1996) BioTechniques , vol.21 , pp. 808-812
    • Wung, J.L.1    Gascoigne, N.R.2
  • 36
    • 0026094226 scopus 로고
    • Production of mouse epidermal growth factor in yeast: High-level secretion using Pichia pastoris strains containing multiple gene copies
    • Clare, J. J., Romanos, M. A., Rayment, F. B., et al. (1991) Production of mouse epidermal growth factor in yeast: high-level secretion using Pichia pastoris strains containing multiple gene copies. Gene 105, 205-212.
    • (1991) Gene , vol.105 , pp. 205-212
    • Clare, J.J.1    Romanos, M.A.2    Rayment, F.B.3
  • 38
    • 0002695549 scopus 로고    scopus 로고
    • Classical genetic manipulation
    • Higgins, D. R, and Cregg, J. M. eds, Humana Press, Totowa, NJ
    • Cregg, J. M., Shen, S., Johnson, M., and Waterham, H. R. (1998) Classical genetic manipulation, in Pichia Protocols, (Higgins, D. R., and Cregg, J. M. eds.), Humana Press, Totowa, NJ.
    • (1998) Pichia Protocols
    • Cregg, J.M.1    Shen, S.2    Johnson, M.3    Waterham, H.R.4
  • 39
    • 0023650956 scopus 로고    scopus 로고
    • Tschopp, J. F., Brust, P. F., Cregg, J. M., Stillman, C. A., and Gingeras, T. R. (1987) Expression of the lacZ gene from two methanol-regulated promoters in Pichia pastoris. Nue. Acids Res. 15, 3859-3876.
    • Tschopp, J. F., Brust, P. F., Cregg, J. M., Stillman, C. A., and Gingeras, T. R. (1987) Expression of the lacZ gene from two methanol-regulated promoters in Pichia pastoris. Nue. Acids Res. 15, 3859-3876.
  • 40
    • 0031610415 scopus 로고    scopus 로고
    • Generation of protease-deficient strains and their use in heterologous protein expression
    • Gleeson, M. A. G., White, C. E., Meninger, D. P., and Komives, E. A. (1998) Generation of protease-deficient strains and their use in heterologous protein expression. Methods Mol. Biol. 103, 81-94.
    • (1998) Methods Mol. Biol , vol.103 , pp. 81-94
    • Gleeson, M.A.G.1    White, C.E.2    Meninger, D.P.3    Komives, E.A.4
  • 41
    • 14744299579 scopus 로고
    • Recent advances in the expression of foreign genes in Pichia pastoris
    • Cregg, J. M., Vedvick, T. S., and Raschke, W. C. (1993) Recent advances in the expression of foreign genes in Pichia pastoris. Bio/Technol 11, 905-910.
    • (1993) Bio/Technol , vol.11 , pp. 905-910
    • Cregg, J.M.1    Vedvick, T.S.2    Raschke, W.C.3
  • 42
    • 14744304041 scopus 로고
    • Rapid selection using G418 of high copy number transformants of Pichia pastoris for high-level foreign gene expression
    • Scorer, C. A., Clare, J. J., McCombie, W. R., Romanos, M. A., and Sreekrishna, K. (1994) Rapid selection using G418 of high copy number transformants of Pichia pastoris for high-level foreign gene expression. Bio/Technol 12, 181-184.
    • (1994) Bio/Technol , vol.12 , pp. 181-184
    • Scorer, C.A.1    Clare, J.J.2    McCombie, W.R.3    Romanos, M.A.4    Sreekrishna, K.5


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