Non-repressing carbon sources for alcohol oxidase (AOX1) promoter of Pichia pastoris

Journal of Bioscience and Bioengineering

Volumn 92, Issue 6, 2001, Pages 585-589

  Inan, Mehmet ^a   Meagher, Michael M ^a  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

AOX1 promoter; Carbon catabolite repression; Pichia pastoris

Indexed keywords

ALCOHOLS; CARBON; ENZYMES; GLUCOSE;

SHAKE FLASK CULTURE;

BIOMEDICAL ENGINEERING;

ALANINE; ALCOHOL OXIDASE; CARBON; GALACTOSE; GLUCOSE; GLYCEROL; MANNITOL; METHANOL; SORBITOL; TREHALOSE;

ARTICLE; ENERGY RESOURCE; FERMENTATION; FUNGAL STRAIN; GROWTH; NONHUMAN; PICHIA PASTORIS;

PICHIA; PICHIA PASTORIS;

EID: 0035703883     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1389-1723(01)80321-2     Document Type: Article

References (25)

1. Recent advances in the expression of foreign genes in Pichia pastoris
2. High cell-density fermentation
3. Foreign gene expression in yeast: A review
4. Development of yeast transformation systems and construction of methanol-utilization-defective mutants of Pichia pastoris by gene disruption
5. Functional characterization of the two alcohol oxidase genes from the yeast Pichia pastoris
6. Fermentation development of recombinant Pichia pastoris expressing the heterologous gene: Bovine lysozyme
7. High-level expression of tetanus toxin fragment C in Pichia pastoris strains containing multiple tandem integrations of the gene
8. Recombinant protein production in an alcohol oxidase-defective strain of Pichia pastoris in fed-batch fermentations
9. Methanol metabolism in yeasts: Regulation of the synthesis of catabolic enzymes
10. Isolation and characterization of a catabolite repression-insensitive mutant of a methanol yeast, Candida boidinii A5, producing alcohol oxidase in glucose-containing medium
11. Genetic control of methanol utilization in yeasts
12. Regulatory flexibility of methylotrophic yeasts in chemostat cultures: Simultaneous assimilation of glucose and methanol at a fixed dilution rate
13. Expression of the lacZ gene from two methanol-regulated promoters in Pichia pastoris
14. The role of peroxisomes in the metabolism of D-alanine in the yeast Candida utilis
15. A versatile set of vectors for constitutive and regulated gene expression in Pichia pastoris
16. Pichia pastoris
17. Strategies for optimal synthesis and secretion of heterologous proteins in the methylotrophic yeast Pichia pastoris
18. Assay of β-galactosidase
19. Fusion of Escherichia coli lacZ to the cytochrome c gene of Saccharomyces cerevisiae
20. Effects of glycerol concentration and pH on growth of recombinant Pichia pastoris yeast
21. The effect of ethanol and acetate on protein expression in Pichia pastoris
22. A novel feeding strategy for enhanced protein production by fed-batch fermentation in recombinant Pichia pastoris
23. Derepression and partial insensitivity to carbon catabolite repression of the methanol dissimilating enzymes in Hansenula polymorpha
24. Regulation of alcohol oxidase synthesis in Hansenula polymorpha: Oversynthesis during growth on mixed substrates and induction by methanol
25. On-line monitoring and control of methanol concentration in shake-flask cultures of Pichia pastoris