Protein secretion in Pichia pastoris and advances in protein production

Applied Microbiology and Biotechnology

Volumn 93, Issue 1, 2012, Pages 31-39

  Damasceno, Leonardo M ^a   Huang, Chung Jr ^b,c   Batt, Carl A ^b  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b Department of Obstetrics Gynecology   (United States)

^c AMGEN INC   (United States)

Author keywords

Pichia pastoris; Protein folding; Recombinant protein secretion; Unfolded protein response

Indexed keywords

ENDOPLASMIC RETICULUM; EXPRESSION SYSTEM; GENE DOSAGE; P. PASTORIS; PICHIA PASTORIS; PROTEIN PRODUCTION; PROTEIN SECRETION; RECOMBINANT PROTEIN; RECOMBINANT PROTEIN EXPRESSION; RECOMBINANT PROTEIN PRODUCTIONS; RECOMBINANT PROTEIN SECRETION; SECRETION OF RECOMBINANT PROTEINS; SECRETOME; SIGNAL SEQUENCE; UNFOLDED PROTEIN RESPONSE; VESICULAR TRANSPORT; YEAST EXPRESSION;

CELL MEMBRANES; GENES; PHYSIOLOGY; PROTEIN FOLDING; YEAST;

PROTEINS;

ACTIVATING TRANSCRIPTION FACTOR 6; ALCOHOL OXIDASE; ARGONAUTE 2 PROTEIN; FUNGAL PROTEIN; RECOMBINANT ERYTHROPOIETIN; RECOMBINANT PROTEIN; RIBONUCLEASE;

GENE EXPRESSION; PROTEIN; RECOMBINATION; SECRETION; YEAST;

AUTOPHOSPHORYLATION; CANDIDA BOIDINII; CELL MEMBRANE; ENDOPLASMIC RETICULUM; EXPRESSION VECTOR; GENE EXPRESSION SYSTEM; GENE SEQUENCE; NONHUMAN; PICHIA; PICHIA METHANOLICA; PICHIA PASTORIS; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN GLYCOSYLATION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; UNFOLDED PROTEIN RESPONSE;

BIOTECHNOLOGY; PICHIA; PROTEIN TRANSPORT; PROTEINS; RECOMBINANT PROTEINS;

PICHIA PASTORIS;

EID: 84856272158     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3654-z     Document Type: Review

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