Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 18, 2009, Pages 7437-7442

  Ho, Joseph D ^a,b   Yeh, Ronald ^b   Sandstrom, Andrew ^b   Chorny, Ilya ^b   Harries, William E C ^b   Robbins, Rebecca A ^b   Miercke, Larry J W ^b   Stroud, Robert M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Brain edema; Inhibitor discovery; NPA motif

Indexed keywords

AQUAPORIN; AQUAPORIN 4; AQUAPORIN Z; UNCLASSIFIED DRUG; WATER; AQP4 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; CHANNEL GATING; CONDUCTANCE; CRYSTAL STRUCTURE; ERYTHROCYTE; HYDROGEN BOND; MAMMAL; MOLECULAR DYNAMICS; MOLECULE; NONHUMAN; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTON TRANSPORT; REGULATORY MECHANISM; SIMULATION; CELL ADHESION; CHEMISTRY; HUMAN; METABOLISM; PROTEIN CONFORMATION; PROTEIN FOLDING; X RAY CRYSTALLOGRAPHY;

MAMMALIA;

AQUAPORIN 4; CELL ADHESION; CRYSTALLOGRAPHY, X-RAY; HUMANS; PROTEIN CONFORMATION; PROTEIN FOLDING; WATER;

EID: 66149097844     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0902725106     Document Type: Article

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