메뉴 건너뛰기




Volumn 40, Issue 1, 2012, Pages 119-129

MicroRNA-125b-2 confers human glioblastoma stem cells resistance to temozolomide through the mitochondrial pathway of apoptosis

Author keywords

Apoptosis; Bax; Bcl 2; MicroRNA; Peptide nucleic acids; Temozolomide

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; MICRORNA; MICRORNA 125B 2; MICRORNA 125B 2 INHIBITOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PEPTIDE NUCLEIC ACID; PROTEIN BAX; PROTEIN BCL 2; SMALL UNTRANSLATED RNA; TEMOZOLOMIDE; UNCLASSIFIED DRUG;

EID: 84455194000     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.1179     Document Type: Article
Times cited : (120)

References (44)
  • 1
    • 0030444288 scopus 로고    scopus 로고
    • Treatment of recurrent malignant gliomas with high-dose 13-cis-retinoic acid
    • Yung WK, Kyritsis AP, Gleason MJ and Levin VA: Treatment of recurrent malignant gliomas with high-dose 13-cis-retinoic acid. Clin Cancer Res 2: 1931-1935, 1996. (Pubitemid 27006624)
    • (1996) Clinical Cancer Research , vol.2 , Issue.12 , pp. 1931-1935
    • Yung, W.K.A.1    Kyritsis, A.P.2    Gleason, M.J.3    Levin, V.A.4
  • 2
    • 0034005995 scopus 로고    scopus 로고
    • Temozolomide, a novel alkylating agent with activity in the central nervous system, may improve the treatment of advanced metastatic melanoma
    • Agarwala SS and Kirkwood JM: Temozolomide, a novel alkylating agent with activity in the central nervous system, may improve the treatment of advanced metastatic melanoma. Oncologist 5: 144-151, 2000.
    • (2000) Oncologist , vol.5 , pp. 144-151
    • Agarwala, S.S.1    Kirkwood, J.M.2
  • 5
    • 9244241576 scopus 로고    scopus 로고
    • Molecular hydrogen beyond the optical edge of an isolated spiral galaxy
    • Singh SK, Hawkins C, Clarke ID, et al.: Molecular hydrogen beyond the optical edge of an isolated spiral galaxy. Nature 432: 396-401, 2004.
    • (2004) Nature , vol.432 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3
  • 7
    • 20444440706 scopus 로고    scopus 로고
    • Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation
    • Lee YS, Kim HK, Chung S, Kim KS and Dutta A: Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation. J Biol Chem 280: 16635-16641, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 16635-16641
    • Lee, Y.S.1    Kim, H.K.2    Chung, S.3    Kim, K.S.4    Dutta, A.5
  • 8
    • 84455162889 scopus 로고    scopus 로고
    • Global microRNA expression analysis in human malignant glioma cells reveals novel miRNA-mediated therapy-resistance mechanisms
    • Winkler JA, Hendricks WP, Johnson D, Xia J and Scheck AC: Global microRNA expression analysis in human malignant glioma cells reveals novel miRNA-mediated therapy-resistance mechanisms. AACR Meeting Abst, 1398, 2005.
    • (2005) AACR Meeting Abst , pp. 1398
    • Winkler, J.A.1    Hendricks, W.P.2    Johnson, D.3    Xia, J.4    Scheck, A.C.5
  • 9
    • 78049330840 scopus 로고    scopus 로고
    • PNA-based antisense oligonucleotides for microrna s inhibition in the absence of a transfection reagent
    • Oh SY, Ju Y, Kim S and Park H: PNA-based antisense oligonucleotides for microrna s inhibition in the absence of a transfection reagent. Oligonucleotides 20: 225-230, 2010.
    • (2010) Oligonucleotides , vol.20 , pp. 225-230
    • Oh, S.Y.1    Ju, Y.2    Kim, S.3    Park, H.4
  • 10
    • 33645059697 scopus 로고    scopus 로고
    • The small organic compound ha14-1 prevents bcl-2 interaction with bax to sensitize malignant glioma cells to induction of cell death
    • Manero F, Gautier F, Gallenne T, Cauquil N, Grée D and Cartron P: The small organic compound ha14-1 prevents bcl-2 interaction with bax to sensitize malignant glioma cells to induction of cell death. Cancer Res 66: 2757-2764, 2006.
    • (2006) Cancer Res , vol.66 , pp. 2757-2764
    • Manero, F.1    Gautier, F.2    Gallenne, T.3    Cauquil, N.4    Grée, D.5    Cartron, P.6
  • 15
    • 77956178738 scopus 로고    scopus 로고
    • MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity
    • Shi L, Chen J, Yang J, et al.: MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity. Brain Res 1352: 255-264, 2010.
    • (2010) Brain Res , vol.1352 , pp. 255-264
    • Shi, L.1    Chen, J.2    Yang, J.3
  • 16
    • 0002857380 scopus 로고
    • The in vitro biology of human brain tumors
    • Thomas DGT (ed.) Johns Hopkins University Press, Baltimore, MD
    • Darling JL: The in vitro biology of human brain tumors. In: Neurooncology: Primary Malignant Brain Tumors. Thomas DGT (ed.) Johns Hopkins University Press, Baltimore, MD, pp1-25, 1990.
    • (1990) Neurooncology: Primary Malignant Brain Tumors , pp. 1-25
    • Darling, J.L.1
  • 17
    • 29144470346 scopus 로고    scopus 로고
    • Real-time quantification of microRNAs by stem-loop RT-PCR
    • Chen C, Ridzon DA, Broomer AJ, et al.: Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res 33: e179, 2005.
    • (2005) Nucleic Acids Res , vol.33
    • Chen, C.1    Ridzon, D.A.2    Broomer, A.J.3
  • 18
    • 0035710746 scopus 로고    scopus 로고
    • -DeltaDeltaCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2 [-Delta Delta C(T)] method. Methods 25: 402-408, 2001. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 20
    • 73649147994 scopus 로고    scopus 로고
    • MiR-125b is critical for the suppression of human U251 glioma stem cell proliferation
    • Shi L, Zhang J, Pan T, Zhou J, et al.: MiR-125b is critical for the suppression of human U251 glioma stem cell proliferation. Brain Res 1312: 120-126, 2010.
    • (2010) Brain Res , vol.1312 , pp. 120-126
    • Shi, L.1    Zhang, J.2    Pan, T.3    Zhou, J.4
  • 22
    • 72449172405 scopus 로고    scopus 로고
    • A highly effective and long-lasting inhibition of miRNAs with PNA-based antisense oligonucleotides
    • Oh SY, Ju Y and Park H: A highly effective and long-lasting inhibition of miRNAs with PNA-based antisense oligonucleotides. Mol Cells 28: 341-345, 2009.
    • (2009) Mol Cells , vol.28 , pp. 341-345
    • Oh, S.Y.1    Ju, Y.2    Park, H.3
  • 23
    • 68249157942 scopus 로고    scopus 로고
    • Glioblastoma stem cells resistant to temozolomide-induced autophagy
    • Fu J, Liu ZG, Liu XM, et al.: Glioblastoma stem cells resistant to temozolomide-induced autophagy. Chin Med J 122: 1255-1259, 2009.
    • (2009) Chin Med J , vol.122 , pp. 1255-1259
    • Fu, J.1    Liu, Z.G.2    Liu, X.M.3
  • 24
    • 0035203755 scopus 로고    scopus 로고
    • Annexin V staining during reperfusion detects cardiomyocytes with unique properties
    • Narayan P, Mentzer RM Jr and Lasley RD: Annexin V staining during reperfusion detects cardiomyocytes with unique properties. Am J Physiol Heart Circ Physiol 281: H1931-H1937, 2001.
    • (2001) Am J Physiol Heart Circ Physiol , vol.281
    • Narayan, P.1    Mentzer Jr., R.M.2    Lasley, R.D.3
  • 25
    • 66749182257 scopus 로고    scopus 로고
    • MiR-125b expression affects the proliferation and apoptosis of human glioma cells by targeting Bmf
    • Xia HF, He TZ, Liu CM, et al.: MiR-125b expression affects the proliferation and apoptosis of human glioma cells by targeting Bmf. Cell Physiol Biochem 23: 347-358, 2009.
    • (2009) Cell Physiol Biochem , vol.23 , pp. 347-358
    • Xia, H.F.1    He, T.Z.2    Liu, C.M.3
  • 26
    • 13644254921 scopus 로고    scopus 로고
    • Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities
    • Das A, Banik NL, Patel SJ and Ray SK: Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities. Mol Cancer 3: 36-45, 2009.
    • (2009) Mol Cancer , vol.3 , pp. 36-45
    • Das, A.1    Banik, N.L.2    Patel, S.J.3    Ray, S.K.4
  • 28
    • 75149132946 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosis
    • Terrano DT, Upreti M and Chambers TC: Cyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosis. Mol Cell Biol 30: 640-656, 2010.
    • (2010) Mol Cell Biol , vol.30 , pp. 640-656
    • Terrano, D.T.1    Upreti, M.2    Chambers, T.C.3
  • 29
    • 0030859359 scopus 로고    scopus 로고
    • Chemotherapy of human malignant glioma: Prevention of efficacy by dexamethasone?
    • Weller M, Schmidt C, Roth W and Dichgans J: Chemotherapy of human malignant glioma: prevention of efficacy by dexamethasone? Neurology 48: 1704-1709, 1997.
    • (1997) Neurology , vol.48 , pp. 1704-1709
    • Weller, M.1    Schmidt, C.2    Roth, W.3    Dichgans, J.4
  • 30
    • 14844320063 scopus 로고    scopus 로고
    • Silymarin induces apoptosis primarily through a p53-dependent pathway involving Bcl-2/Bax, cytochrome c release, and caspase activation
    • Katiyar SK, Roy AM and Baliga MS: Silymarin induces apoptosis primarily through a p53-dependent pathway involving Bcl-2/Bax, cytochrome c release, and caspase activation. Mol Cancer Ther 4: 207-216, 2005. (Pubitemid 40340200)
    • (2005) Molecular Cancer Therapeutics , vol.4 , Issue.2 , pp. 207-216
    • Katiyar, S.K.1    Roy, A.M.2    Baliga, M.S.3
  • 31
    • 1442264399 scopus 로고    scopus 로고
    • Apoptotic Proteins in the Temporal Cortex in Schizophrenia: High Bax/Bcl-2 Ratio without Caspase-3 Activation
    • DOI 10.1176/appi.ajp.161.1.109
    • Jarskog LF, Selinger ES, Lieberman JA and Gilmore JH: Apoptotic proteins in the temporal cortex in schizophrenia: high bax/bcl-2 ratio without caspase-3 activation. Am J Psychiatry 161: 109-115, 2004. (Pubitemid 38419315)
    • (2004) American Journal of Psychiatry , vol.161 , Issue.1 , pp. 109-115
    • Jarskog, L.F.1    Selinger, E.S.2    Lieberman, J.A.3    Gilmore, J.H.4
  • 32
    • 0035266245 scopus 로고    scopus 로고
    • 2/M arrest and the fate of temozolomide-treated human glioblastoma cells
    • Hirose Y, Berger MS and Pieper RO: p53 effects both the duration of G2/M arrest and the fate of Temozolomide-treated human glioblastoma cells. Cancer Res 61: 1957-1963, 2001. (Pubitemid 32692013)
    • (2001) Cancer Research , vol.61 , Issue.5 , pp. 1957-1963
    • Hirose, Y.1    Berger, M.S.2    Pieper, R.O.3
  • 33
    • 33750707236 scopus 로고    scopus 로고
    • Metronomic treatment of temozolomide inhibits tumor cell growth through reduction of angiogenesis and augmentation of apoptosis in orthotopic models of gliomas
    • Kim JT, Kim JS, Ko KW, et al.: Metronomic treatment of temozolomide inhibits tumor cell growth through reduction of angiogenesis and augmentation of apoptosis in orthotopic models of gliomas. Oncol Rep 16: 33-39, 2006.
    • (2006) Oncol Rep , vol.16 , pp. 33-39
    • Kim, J.T.1    Kim, J.S.2    Ko, K.W.3
  • 34
    • 77954643043 scopus 로고    scopus 로고
    • Autophagy induced by valproic acid is associated with oxidative stress in glioma cell lines
    • Fu J, Shao CJ, Chen FR, Ng HK and Chen ZP: Autophagy induced by valproic acid is associated with oxidative stress in glioma cell lines. Neurooncology 12: 328-340, 2010.
    • (2010) Neurooncology , vol.12 , pp. 328-340
    • Fu, J.1    Shao, C.J.2    Chen, F.R.3    Ng, H.K.4    Chen, Z.P.5
  • 35
    • 66149147850 scopus 로고    scopus 로고
    • Ischemia-reperfusioninducible protein modulates cell sensitivity to anticancer drugs by regulating activity of efflux transporter
    • Prokopenko O and Mirochnitchenko O: Ischemia-reperfusioninducible protein modulates cell sensitivity to anticancer drugs by regulating activity of efflux transporter. Am J Physiol Cell Physiol 296: C1086-C1097, 2009.
    • (2009) Am J Physiol Cell Physiol , vol.296
    • Prokopenko, O.1    Mirochnitchenko, O.2
  • 36
    • 65849520676 scopus 로고    scopus 로고
    • Current tools for the identification of miRNA genes and their targets
    • Mendes ND, Freitas AT and Sagot MF: Current tools for the identification of miRNA genes and their targets. Nucleic Acids Res 37: 2419-2433, 2009.
    • (2009) Nucleic Acids Res , vol.37 , pp. 2419-2433
    • Mendes, N.D.1    Freitas, A.T.2    Sagot, M.F.3
  • 37
    • 0028972616 scopus 로고
    • Regulation of apoptosis by Bcl-2 family proteins and its role in cancer and chemoresistance
    • Reed JC: Regulation of apoptosis by Bcl-2 family proteins and its role in cancer and chemoresistance. Curr Opin Oncol 7: 541-546, 1995.
    • (1995) Curr Opin Oncol , vol.7 , pp. 541-546
    • Reed, J.C.1
  • 38
    • 0035370483 scopus 로고    scopus 로고
    • Regulation and function of the p53 tumor suppressor protein
    • DOI 10.1016/S0955-0674(00)00216-7
    • Ryan KM, Phillips AC and Vousden KH: Regulation and function of the p53 tumor suppressor protein. Curr Opin Cell Biol 13: 332-337, 2001. (Pubitemid 32429498)
    • (2001) Current Opinion in Cell Biology , vol.13 , Issue.3 , pp. 332-337
    • Ryan, K.M.1    Phillips, A.C.2    Vousden, K.H.3
  • 39
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene Bcl-2 and its role in regulating apoptosis
    • Kroemer G: The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat Med 3: 614-620, 1997.
    • (1997) Nat Med , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 40
    • 0032075590 scopus 로고    scopus 로고
    • Bcl-2 regulates nonapoptotic signal transduction: Inhibition of c-Jun N- terminal kinase (JNK) activation by IL-1beta and hydrogen peroxide
    • DOI 10.1006/mgme.1998.2704
    • Lee L, Irani K and Finkel T: Bcl-2 regulates non-apoptotic signal transduction: inhibition of c-Jun N-terminal kinase (JNK) activation by IL-1 beta and hydrogen peroxide. Mol Genet Metab 64: 19-24, 1998. (Pubitemid 28453314)
    • (1998) Molecular Genetics and Metabolism , vol.64 , Issue.1 , pp. 19-24
    • Lee, L.1    Irani, K.2    Finkel, T.3
  • 41
    • 0036536697 scopus 로고    scopus 로고
    • Biochemical changes associated with a multidrug-resistant phenotype of a human glioma cell line with temozolomide-acquired resistance
    • DOI 10.1016/S0006-2952(02)00876-6, PII S0006295202008766
    • Ma J, Murphy M, O'Dwyer PJ, Berman E, Reed K and Gallo JM: Biochemical changes associated with a multidrug-resistant phenotype of a human glioma cell line with temozolomideacquired resistance. Biochem Pharmacol 63: 1219-1228, 2002. (Pubitemid 34311991)
    • (2002) Biochemical Pharmacology , vol.63 , Issue.7 , pp. 1219-1228
    • Ma, J.1    Murphy, M.2    O'Dwyer, P.J.3    Berman, E.4    Reed, K.5    Gallo, J.M.6
  • 42
    • 0342978014 scopus 로고    scopus 로고
    • Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-x(L) has activity independent of cytochrome c release
    • DOI 10.1074/jbc.272.48.30299
    • Li F, Srinivasan A, Wang Y, Armstrong RC, Tomaselli KJ and Fritz LC: Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release. J Biol Chem 272: 30299-30305, 1997. (Pubitemid 27512235)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.48 , pp. 30299-30305
    • Li, F.1    Srinivasan, A.2    Wang, Y.3    Armstrong, R.C.4    Tomaselli, K.J.5    Fritz, L.C.6
  • 43
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl- 2 regulation of apoptosis
    • DOI 10.1126/science.275.5303.1132
    • Kluck RM, Bossy-Wetzel E, Green DR and Newmeyer DD: The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275: 1132-1136, 1997. (Pubitemid 27097313)
    • (1997) Science , vol.275 , Issue.5303 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.