-
1
-
-
23744489378
-
P2X(7)Receptor: Death or life?
-
doi: 10.1007/s11302-005-6322-x
-
Adinolfi, E., Pizzirani, C., Idzko, M., Panther, E., Norgauer, J., Di Virgilio, F., et al. (2005). P2X(7)Receptor: death or life? Purinergic Signal. 1, 219-227. doi: 10.1007/s11302-005-6322-x
-
(2005)
Purinergic Signal
, vol.1
, pp. 219-227
-
-
Adinolfi, E.1
Pizzirani, C.2
Idzko, M.3
Panther, E.4
Norgauer, J.5
Di Virgilio, F.6
-
2
-
-
84883210637
-
Is pannexin the pore associated with the P2X7 receptor?
-
doi: 10.1007/s00210-013-0868-x
-
Alberto, A. V., Faria, R. X., Couto, C. G., Ferreira, L. G., Souza, C. A., Teixeira, P. C., et al. (2013). Is pannexin the pore associated with the P2X7 receptor? Naunyn Schmiedebergs Arch. Pharmacol. 386, 775-787. doi: 10.1007/s00210-013-0868-x
-
(2013)
Naunyn Schmiedebergs Arch. Pharmacol
, vol.386
, pp. 775-787
-
-
Alberto, A.V.1
Faria, R.X.2
Couto, C.G.3
Ferreira, L.G.4
Souza, C.A.5
Teixeira, P.C.6
-
3
-
-
58249113980
-
Mammalian nicotinic acetylcholine receptors: From structure to function
-
doi: 10.1152/physrev.00015.2008
-
Albuquerque, E. X., Pereira, E. F., Alkondon, M., and Rogers, S. W. (2009). Mammalian nicotinic acetylcholine receptors: from structure to function. Physiol. Rev. 89, 73-120. doi: 10.1152/physrev.00015.2008
-
(2009)
Physiol. Rev
, vol.89
, pp. 73-120
-
-
Albuquerque, E.X.1
Pereira, E.F.2
Alkondon, M.3
Rogers, S.W.4
-
4
-
-
80051696222
-
Cysteine scanning mutagenesis (residues Glu52-Gly96) of the human P2X1 receptor for ATP: Mapping agonist binding and channel gating
-
doi: 10.1074/jbc.M111.260364
-
Allsopp, R. C., El Ajouz, S., Schmid, R., and Evans, R. J. (2011). Cysteine scanning mutagenesis (residues Glu52-Gly96) of the human P2X1 receptor for ATP: mapping agonist binding and channel gating. J. Biol. Chem. 286, 29207-29217. doi: 10.1074/jbc.M111.260364
-
(2011)
J. Biol. Chem
, vol.286
, pp. 29207-29217
-
-
Allsopp, R.C.1
El Ajouz, S.2
Schmid, R.3
Evans, R.J.4
-
5
-
-
4143136452
-
Trimeric architecture of homomeric P2X2 and heteromeric P2X1+2 receptor subtypes
-
doi: 10.1016/j.jmb.2004.06.092
-
Aschrafi, A., Sadtler, S., Niculescu, C., Rettinger, J., and Schmalzing, G. (2004). Trimeric architecture of homomeric P2X2 and heteromeric P2X1+2 receptor subtypes. J. Mol. Biol. 342, 333-343. doi: 10.1016/j.jmb.2004.06.092
-
(2004)
J. Mol. Biol
, vol.342
, pp. 333-343
-
-
Aschrafi, A.1
Sadtler, S.2
Niculescu, C.3
Rettinger, J.4
Schmalzing, G.5
-
6
-
-
84866519244
-
Structural plasticity and dynamic selectivity of acid-sensing ion channel-spider toxin complexes
-
doi: 10.1038/nature11375
-
Baconguis, I., and Gouaux, E. (2012). Structural plasticity and dynamic selectivity of acid-sensing ion channel-spider toxin complexes. Nature 489, 400-405. doi: 10.1038/nature11375
-
(2012)
Nature
, vol.489
, pp. 400-405
-
-
Baconguis, I.1
Gouaux, E.2
-
7
-
-
77952650740
-
Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation
-
doi: 10.1152/ajpcell.00489.2009
-
Banke, T. G., Chaplan, S. R., and Wickenden, A. D. (2010). Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation. Am. J. Physiol. Cell Physiol. 298, C1457-C1468. doi: 10.1152/ajpcell.00489.2009
-
(2010)
Am. J. Physiol. Cell Physiol
, vol.298
-
-
Banke, T.G.1
Chaplan, S.R.2
Wickenden, A.D.3
-
8
-
-
15444372454
-
AFM imaging demonstrates that P2X2 receptors are trimers, but that P2X6 receptor subunits do not oligomerize
-
doi: 10.1074/jbc.M412265200
-
Barrera, N. P., Ormond, S. J., Henderson, R. M., Murrell-Lagnado, R. D., and Edwardson, J. M. (2005). AFM imaging demonstrates that P2X2 receptors are trimers, but that P2X6 receptor subunits do not oligomerize. J. Biol. Chem. 280, 10759-10765. doi: 10.1074/jbc.M412265200
-
(2005)
J. Biol. Chem
, vol.280
, pp. 10759-10765
-
-
Barrera, N.P.1
Ormond, S.J.2
Henderson, R.M.3
Murrell-Lagnado, R.D.4
Edwardson, J.M.5
-
9
-
-
0026336870
-
Changes in cytoplasmic calcium induced by purinergic P2x receptor activation in vascular smooth muscle cells and sensory neurons
-
doi: 10.1007/978-1-4684-6003-2_19
-
Benham, C. D., Bouvier, M. M., and Evans, M. L. (1991). Changes in cytoplasmic calcium induced by purinergic P2x receptor activation in vascular smooth muscle cells and sensory neurons. Adv. Exp. Med. Biol. 304, 229-239. doi: 10.1007/978-1-4684-6003-2_19
-
(1991)
Adv. Exp. Med. Biol
, vol.304
, pp. 229-239
-
-
Benham, C.D.1
Bouvier, M.M.2
Evans, M.L.3
-
10
-
-
84858070953
-
P2X4 receptor channels form large noncytolytic pores in resting and activated microglia
-
doi: 10.1002/glia.22301
-
Bernier, L. P., Ase, A. R., Boue-Grabot, E., and Seguela, P. (2012). P2X4 receptor channels form large noncytolytic pores in resting and activated microglia. Glia 60, 728-737. doi: 10.1002/glia.22301
-
(2012)
Glia
, vol.60
, pp. 728-737
-
-
Bernier, L.P.1
Ase, A.R.2
Boue-Grabot, E.3
Seguela, P.4
-
11
-
-
34948819283
-
Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers
-
doi: 10.1038/nature06191
-
Binshtok, A. M., Bean, B. P., and Woolf, C. J. (2007). Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers. Nature 449, 607-610. doi: 10.1038/nature06191
-
(2007)
Nature
, vol.449
, pp. 607-610
-
-
Binshtok, A.M.1
Bean, B.P.2
Woolf, C.J.3
-
12
-
-
0038441333
-
Pharmacological and biophysical properties of the human P2X5 receptor
-
doi: 10.1124/mol.63.6.1407
-
Bo, X., Jiang, L. H., Wilson, H. L., Kim, M., Burnstock, G., Surprenant, A., et al. (2003). Pharmacological and biophysical properties of the human P2X5 receptor. Mol. Pharmacol. 63, 1407-1416. doi: 10.1124/mol.63.6.1407
-
(2003)
Mol. Pharmacol
, vol.63
, pp. 1407-1416
-
-
Bo, X.1
Jiang, L.H.2
Wilson, H.L.3
Kim, M.4
Burnstock, G.5
Surprenant, A.6
-
13
-
-
0033555821
-
ATP stimulates sympathetic transmitter release via presynaptic P2X purinoceptors
-
Boehm, S. (1999). ATP stimulates sympathetic transmitter release via presynaptic P2X purinoceptors. J. Neurosci. 19, 737-746.
-
(1999)
J. Neurosci
, vol.19
, pp. 737-746
-
-
Boehm, S.1
-
14
-
-
0040609340
-
A protein kinase C site highly conserved in P2X subunits controls the desensitization kinetics of P2X(2) ATP-gated channels
-
doi: 10.1074/jbc.275.14.10190
-
Boue-Grabot, E., Archambault, V., and Seguela, P. (2000). A protein kinase C site highly conserved in P2X subunits controls the desensitization kinetics of P2X(2) ATP-gated channels. J. Biol. Chem. 275, 10190-10195. doi: 10.1074/jbc.275.14.10190
-
(2000)
J. Biol. Chem
, vol.275
, pp. 10190-10195
-
-
Boue-Grabot, E.1
Archambault, V.2
Seguela, P.3
-
15
-
-
0348133543
-
The sources and sequestration of Ca(2+) contributing to neuroeffector Ca(2+) transients in the mouse vas deferens
-
doi: 10.1113/jphysiol.2003.049734
-
Brain, K. L., Cuprian, A. M., Williams, D. J., and Cunnane, T. C. (2003). The sources and sequestration of Ca(2+) contributing to neuroeffector Ca(2+) transients in the mouse vas deferens. J. Physiol. 553, 627-635. doi: 10.1113/jphysiol.2003.049734
-
(2003)
J. Physiol
, vol.553
, pp. 627-635
-
-
Brain, K.L.1
Cuprian, A.M.2
Williams, D.J.3
Cunnane, T.C.4
-
16
-
-
0028025001
-
New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor
-
doi: 10.1038/371519a0
-
Brake, A. J., Wagenbach, M. J., and Julius, D. (1994). New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor. Nature 371, 519-523. doi: 10.1038/371519a0
-
(1994)
Nature
, vol.371
, pp. 519-523
-
-
Brake, A.J.1
Wagenbach, M.J.2
Julius, D.3
-
17
-
-
0028937070
-
Nonselective cationic currents elicited by extracellular ATP in human B-lymphocytes
-
doi: 10.1007/BF00373990
-
Bretschneider, F., Klapperstuck, M., Lohn, M., and Markwardt, F. (1995). Nonselective cationic currents elicited by extracellular ATP in human B-lymphocytes. Pflugers Arch. 429, 691-698. doi: 10.1007/BF00373990
-
(1995)
Pflugers Arch
, vol.429
, pp. 691-698
-
-
Bretschneider, F.1
Klapperstuck, M.2
Lohn, M.3
Markwardt, F.4
-
18
-
-
78650677994
-
P2X receptor channels show threefold symmetry in ionic charge selectivity and unitary conductance
-
doi: 10.1038/nn.2705
-
Browne, L. E., Cao, L., Broomhead, H. E., Bragg, L., Wilkinson, W. J., and North, R. A. (2011). P2X receptor channels show threefold symmetry in ionic charge selectivity and unitary conductance. Nat. Neurosci. 14, 17-18. doi: 10.1038/nn.2705
-
(2011)
Nat. Neurosci
, vol.14
, pp. 17-18
-
-
Browne, L.E.1
Cao, L.2
Broomhead, H.E.3
Bragg, L.4
Wilkinson, W.J.5
North, R.A.6
-
19
-
-
84874195644
-
P2X7 receptor channels allow direct permeation of nanometer-sized dyes
-
doi: 10.1523/JNEUROSCI.2235-12.2013
-
Browne, L. E., Compan, V., Bragg, L., and North, R. A. (2013). P2X7 receptor channels allow direct permeation of nanometer-sized dyes. J. Neurosci. 33, 3557-3566. doi: 10.1523/JNEUROSCI.2235-12.2013
-
(2013)
J. Neurosci
, vol.33
, pp. 3557-3566
-
-
Browne, L.E.1
Compan, V.2
Bragg, L.3
North, R.A.4
-
20
-
-
0032420182
-
Calcium permeability of ligand-gated channels
-
doi: 10.1016/S0143-4160(98)90056-2
-
Burnashev, N. (1998). Calcium permeability of ligand-gated channels. Cell Calcium 24, 325-332. doi: 10.1016/S0143-4160(98)90056-2
-
(1998)
Cell Calcium
, vol.24
, pp. 325-332
-
-
Burnashev, N.1
-
21
-
-
79955957628
-
P2X receptors in health and disease
-
doi: 10.1016/B978-0-12-385526-8.00011-4
-
Burnstock, G., and Kennedy, C. (2011). P2X receptors in health and disease. Adv. Pharmacol. 61, 333-372. doi: 10.1016/B978-0-12-385526-8.00011-4
-
(2011)
Adv. Pharmacol
, vol.61
, pp. 333-372
-
-
Burnstock, G.1
Kennedy, C.2
-
22
-
-
73149109743
-
P2X7 receptor activates multiple selective dye-permeation pathways in RAW 264.7 and human embryonic kidney 293 cells
-
doi: 10.1124/mol.109.059923
-
Cankurtaran-Sayar, S., Sayar, K., and Ugur, M. (2009). P2X7 receptor activates multiple selective dye-permeation pathways in RAW 264.7 and human embryonic kidney 293 cells. Mol. Pharmacol. 76, 1323-1332. doi: 10.1124/mol.109.059923
-
(2009)
Mol. Pharmacol
, vol.76
, pp. 1323-1332
-
-
Cankurtaran-Sayar, S.1
Sayar, K.2
Ugur, M.3
-
23
-
-
84859757951
-
Contribution of residues in second transmembrane domain of ASIC1a protein to ion selectivity
-
doi: 10.1074/jbc.M111.329284
-
Carattino, M. D., and Della Vecchia, M. C. (2012). Contribution of residues in second transmembrane domain of ASIC1a protein to ion selectivity. J. Biol. Chem. 287, 12927-12934. doi: 10.1074/jbc.M111.329284
-
(2012)
J. Biol. Chem
, vol.287
, pp. 12927-12934
-
-
Carattino, M.D.1
Della Vecchia, M.C.2
-
24
-
-
84861716984
-
Voltage-gated sodium channels at 60: Structure, function and pathophysiology
-
doi: 10.1113/jphysiol.2011.224204
-
Catterall, W. A. (2012). Voltage-gated sodium channels at 60: structure, function and pathophysiology. J. Physiol. 590, 2577-2589. doi: 10.1113/jphysiol.2011.224204
-
(2012)
J. Physiol
, vol.590
, pp. 2577-2589
-
-
Catterall, W.A.1
-
25
-
-
84867240374
-
The Hodgkin-Huxley heritage: From channels to circuits
-
doi: 10.1523/JNEUROSCI.3403-12.2012
-
Catterall, W. A., Raman, I. M., Robinson, H. P., Sejnowski, T. J., and Paulsen, O. (2012). The Hodgkin-Huxley heritage: from channels to circuits. J. Neurosci. 32, 14064-14073. doi: 10.1523/JNEUROSCI.3403-12.2012
-
(2012)
J. Neurosci
, vol.32
, pp. 14064-14073
-
-
Catterall, W.A.1
Raman, I.M.2
Robinson, H.P.3
Sejnowski, T.J.4
Paulsen, O.5
-
26
-
-
58149237912
-
Regulation of P2X2 receptors by the neuronal calcium sensor VILIP1
-
doi: 10.1126/scisignal.1162329
-
Chaumont, S., Compan, V., Toulme, E., Richler, E., Housley, G. D., Rassendren, F., et al. (2008) Regulation of P2X2 receptors by the neuronal calcium sensor VILIP1. Sci. Signal. 1, ra8. doi: 10.1126/scisignal.1162329
-
(2008)
Sci. Signal
, vol.1
-
-
Chaumont, S.1
Compan, V.2
Toulme, E.3
Richler, E.4
Housley, G.D.5
Rassendren, F.6
-
27
-
-
42649095142
-
TRPV1 shows dynamic ionic selectivity during agonist stimulation
-
doi: 10.1038/nn.2102
-
Chung, M. K., Guler, A. D., and Caterina, M. J. (2008). TRPV1 shows dynamic ionic selectivity during agonist stimulation. Nat. Neurosci. 11, 555-564. doi: 10.1038/nn.2102
-
(2008)
Nat. Neurosci
, vol.11
, pp. 555-564
-
-
Chung, M.K.1
Guler, A.D.2
Caterina, M.J.3
-
28
-
-
79955950645
-
Activation and regulation of purinergic P2X receptor channels
-
doi: 10.1124/pr.110.003129
-
Coddou, C., Yan, Z., Obsil, T., Huidobro-Toro, J. P., and Stojilkovic, S. S. (2011). Activation and regulation of purinergic P2X receptor channels. Pharmacol. Rev. 63, 641-683. doi: 10.1124/pr.110.003129
-
(2011)
Pharmacol. Rev
, vol.63
, pp. 641-683
-
-
Coddou, C.1
Yan, Z.2
Obsil, T.3
Huidobro-Toro, J.P.4
Stojilkovic, S.S.5
-
29
-
-
84858408591
-
P2X2 and P2X5 subunits define a new heteromeric receptor with P2X7-like properties
-
doi: 10.1523/JNEUROSCI.6332-11.2012
-
Compan, V., Ulmann, L., Stelmashenko, O., Chemin, J., Chaumont, S., and Rassendren, F. (2012). P2X2 and P2X5 subunits define a new heteromeric receptor with P2X7-like properties J. Neurosci. 32, 4284-4296. doi: 10.1523/JNEUROSCI.6332-11.2012
-
(2012)
J. Neurosci
, vol.32
, pp. 4284-4296
-
-
Compan, V.1
Ulmann, L.2
Stelmashenko, O.3
Chemin, J.4
Chaumont, S.5
Rassendren, F.6
-
30
-
-
0030922667
-
Distinct ATP receptors on pain-sensing and stretch-sensing neurons
-
doi: 10.1038/387505a0
-
Cook, S. P., Vulchanova, L., Hargreaves, K. M., Elde, R., and McCleskey, E. W. (1997). Distinct ATP receptors on pain-sensing and stretch-sensing neurons. Nature 387, 505-508. doi: 10.1038/387505a0
-
(1997)
Nature
, vol.387
, pp. 505-508
-
-
Cook, S.P.1
Vulchanova, L.2
Hargreaves, K.M.3
Elde, R.4
McCleskey, E.W.5
-
31
-
-
79953161602
-
Terminus of the P2X7 receptor: Treasure hunting
-
doi: 10.1007/s11302-011-9215-1
-
Costa-Junior, H. M., Sarmento Vieira, F., and Coutinho-Silva, R. (2011). Terminus of the P2X7 receptor: treasure hunting. Purinergic Signal. 7, 7-19. doi: 10.1007/s11302-011-9215-1
-
(2011)
Purinergic Signal
, vol.7
, pp. 7-19
-
-
Costa-Junior, H.M.1
Sarmento Vieira, F.2
Coutinho-Silva, R.3
-
32
-
-
0032732474
-
Ion permeation and block of P2X(2) purinoceptors: Single channel recordings
-
doi: 10.1007/s002329900598
-
Ding, S., and Sachs, F. (1999a). Ion permeation and block of P2X(2) purinoceptors: single channel recordings. J. Membr. Biol. 172, 215-223. doi: 10.1007/s002329900598
-
(1999)
J. Membr. Biol
, vol.172
, pp. 215-223
-
-
Ding, S.1
Sachs, F.2
-
33
-
-
0032940264
-
Single channel properties of P2X2 purinoceptors
-
doi: 10.1085/jgp.113.5.695
-
Ding, S., and Sachs, F. (1999b). Single channel properties of P2X2 purinoceptors. J. Gen. Physiol. 113, 695-720. doi: 10.1085/jgp.113.5.695
-
(1999)
J. Gen. Physiol
, vol.113
, pp. 695-720
-
-
Ding, S.1
Sachs, F.2
-
34
-
-
84868248487
-
Purines, purinergic receptors, and cance
-
doi: 10.1158/0008-5472.CAN-12-1600
-
Di Virgilio, F. (2012). Purines, purinergic receptors, and cance. Cancer Res. 72, 5441-5447. doi: 10.1158/0008-5472.CAN-12-1600
-
(2012)
Cancer Res
, vol.72
, pp. 5441-5447
-
-
Di Virgilio, F.1
-
35
-
-
40449114454
-
Metals in proteins: Correlation between the metal-ion type, coordination number and the amino-acid residues involved in the coordination
-
doi: 10.1107/S090744490706595X
-
Dokmanic, I., Sikic, M., and Tomic, S. (2008). Metals in proteins: correlation between the metal-ion type, coordination number and the amino-acid residues involved in the coordination. Acta Crystallogr. D Biol. Crystallogr. 64, 257-263. doi: 10.1107/S090744490706595X
-
(2008)
Acta Crystallogr. D Biol. Crystallogr
, vol.64
, pp. 257-263
-
-
Dokmanic, I.1
Sikic, M.2
Tomic, S.3
-
36
-
-
1342323323
-
Mitogen-activated protein kinase and caspase signaling pathways are required for P2X7 receptor (P2X7R)-induced pore formation in human THP-1 cells
-
doi: 10.1124/jpet.103.059600
-
Donnelly-Roberts, D. L., Namovic, M. T., Faltynek, C. R., and Jarvis, M. F. (2004). Mitogen-activated protein kinase and caspase signaling pathways are required for P2X7 receptor (P2X7R)-induced pore formation in human THP-1 cells. J. Pharmacol. Exp. Ther. 308, 1053-1061. doi: 10.1124/jpet.103.059600
-
(2004)
J. Pharmacol. Exp. Ther
, vol.308
, pp. 1053-1061
-
-
Donnelly-Roberts, D.L.1
Namovic, M.T.2
Faltynek, C.R.3
Jarvis, M.F.4
-
37
-
-
0031689402
-
P2X receptor-mediated excitation of nociceptive afferents in the normal and arthritic rat knee joint
-
doi: 10.1038/sj.bjp.0702080
-
Dowd, E., McQueen, D. S., Chessell, I. P., and Humphrey, P. P. (1998). P2X receptor-mediated excitation of nociceptive afferents in the normal and arthritic rat knee joint. Br. J. Pharmacol. 125, 341-346. doi: 10.1038/sj.bjp.0702080
-
(1998)
Br. J. Pharmacol
, vol.125
, pp. 341-346
-
-
Dowd, E.1
McQueen, D.S.2
Chessell, I.P.3
Humphrey, P.P.4
-
38
-
-
2542464972
-
Structural changes during ion channel gating
-
doi: 10.1016/j.tins.2004.04.004
-
Doyle, D. A. (2004). Structural changes during ion channel gating. Trends Neurosci. 27, 298-302. doi: 10.1016/j.tins.2004.04.004
-
(2004)
Trends Neurosci
, vol.27
, pp. 298-302
-
-
Doyle, D.A.1
-
39
-
-
0032053981
-
A domain contributing to the ion channel of ATP-gated P2X2 receptors identified by the substituted cysteine accessibility method
-
Egan, T. M., Haines, W. R., and Voigt, M. M. (1998). A domain contributing to the ion channel of ATP-gated P2X2 receptors identified by the substituted cysteine accessibility method. J. Neurosci. 18, 2350-2359.
-
(1998)
J. Neurosci
, vol.18
, pp. 2350-2359
-
-
Egan, T.M.1
Haines, W.R.2
Voigt, M.M.3
-
40
-
-
1842558753
-
Contribution of calcium ions to P2X channel responses
-
doi: 10.1523/JNEUROSCI.5429-03.2004
-
Egan, T. M., and Khakh, B. S. (2004). Contribution of calcium ions to P2X channel responses. J. Neurosci. 24, 3413-3420. doi: 10.1523/JNEUROSCI.5429-03.2004
-
(2004)
J. Neurosci
, vol.24
, pp. 3413-3420
-
-
Egan, T.M.1
Khakh, B.S.2
-
41
-
-
33745753599
-
Biophysics of P2X receptors
-
doi: 10.1007/s00424-006-0078-1
-
Egan, T. M., Samways, D. S., and Li, Z. (2006). Biophysics of P2X receptors. Pflugers Arch. 452, 501-512. doi: 10.1007/s00424-006-0078-1
-
(2006)
Pflugers Arch
, vol.452
, pp. 501-512
-
-
Egan, T.M.1
Samways, D.S.2
Li, Z.3
-
42
-
-
0023061436
-
An introduction to molecular architecture and permeability of ion channels
-
doi: 10.1146/annurev.bb.16.060187.001225
-
Eisenman, G., and Dani, J. A. (1987). An introduction to molecular architecture and permeability of ion channels. Annu. Rev. Biophys. Biophys. Chem. 16, 205-226. doi: 10.1146/annurev.bb.16.060187.001225
-
(1987)
Annu. Rev. Biophys. Biophys. Chem
, vol.16
, pp. 205-226
-
-
Eisenman, G.1
Dani, J.A.2
-
43
-
-
0021070747
-
Ionic selectivity revisited: The role of kinetic and equilibrium processes in ion permeation through channels
-
doi: 10.1007/BF01870364
-
Eisenman, G., and Horn, R. (1983). Ionic selectivity revisited: the role of kinetic and equilibrium processes in ion permeation through channels. J. Membr. Biol. 76, 197-225. doi: 10.1007/BF01870364
-
(1983)
J. Membr. Biol
, vol.76
, pp. 197-225
-
-
Eisenman, G.1
Horn, R.2
-
44
-
-
0036290377
-
P2X(1) Receptor subunit contribution to gating revealed by a dominant negative PKC mutant
-
doi: 10.1006/bbrc.2002.6488
-
Ennion, S. J., and Evans, R. J. (2002). P2X(1) Receptor subunit contribution to gating revealed by a dominant negative PKC mutant. Biochem. Biophys. Res. Commun. 291, 611-616. doi: 10.1006/bbrc.2002.6488
-
(2002)
Biochem. Biophys. Res. Commun
, vol.291
, pp. 611-616
-
-
Ennion, S.J.1
Evans, R.J.2
-
45
-
-
0030593493
-
Single channel properties of ATP-gated cation channels (P2X receptors) heterologously expressed in Chinese hamster ovary cells
-
doi: 10.1016/0304-3940(96)12804-4
-
Evans, R. J. (1996). Single channel properties of ATP-gated cation channels (P2X receptors) heterologously expressed in Chinese hamster ovary cells. Neurosci. Lett. 212, 212-214. doi: 10.1016/0304-3940(96)12804-4
-
(1996)
Neurosci. Lett
, vol.212
, pp. 212-214
-
-
Evans, R.J.1
-
46
-
-
0029955763
-
Ionic permeability of, and divalent cation effects on, two ATP-gated cation channels (P2X receptors) expressed in mammalian cells
-
Evans, R. J., Lewis, C., Virginio, C., Lundstrom, K., Buell, G., Surprenant, A., et al. (1996). Ionic permeability of, and divalent cation effects on, two ATP-gated cation channels (P2X receptors) expressed in mammalian cells. J. Physiol. 497(Pt 2), 413-422.
-
(1996)
J. Physiol
, vol.497
, Issue.PART 2
, pp. 413-422
-
-
Evans, R.J.1
Lewis, C.2
Virginio, C.3
Lundstrom, K.4
Buell, G.5
Surprenant, A.6
-
47
-
-
12144283595
-
Are second messengers crucial for opening the pore associated with P2X7 receptor?
-
doi: 10.1152/ajpcell.00215.2004
-
Faria, R. X., Defarias, F. P., and Alves, L. A. (2005). Are second messengers crucial for opening the pore associated with P2X7 receptor? Am. J. Physiol. Cell Physiol. 288, C260-C271. doi: 10.1152/ajpcell.00215.2004
-
(2005)
Am. J. Physiol. Cell Physiol
, vol.288
-
-
Faria, R.X.1
Defarias, F.P.2
Alves, L.A.3
-
48
-
-
67650071224
-
Pharmacological properties of a pore induced by raising intracellular Ca2+
-
doi: 10.1152/ajpcell.00476.2008
-
Faria, R. X., Reis, R. A., Casabulho, C. M., Alberto, A. V., de Farias, F. P., Henriques-Pons, A., et al. (2009). Pharmacological properties of a pore induced by raising intracellular Ca2+. Am. J. Physiol. Cell Physiol. 297, C28-C42. doi: 10.1152/ajpcell.00476.2008
-
(2009)
Am. J. Physiol. Cell Physiol
, vol.297
-
-
Faria, R.X.1
Reis, R.A.2
Casabulho, C.M.3
Alberto, A.V.4
de Farias, F.P.5
Henriques-Pons, A.6
-
49
-
-
47249090581
-
Permeation properties of a P2X receptor in the green algae Ostreococcus tauri
-
doi: 10.1074/jbc.M801512200
-
Fountain, S. J., Cao, L., Young, M. T., and North, R. A. (2008). Permeation properties of a P2X receptor in the green algae Ostreococcus tauri. J. Biol. Chem. 283, 15122-15126. doi: 10.1074/jbc.M801512200
-
(2008)
J. Biol. Chem
, vol.283
, pp. 15122-15126
-
-
Fountain, S.J.1
Cao, L.2
Young, M.T.3
North, R.A.4
-
50
-
-
0347359010
-
Ca2+ permeability of nicotinic acetylcholine receptors
-
doi: 10.1016/j.ceca.2003.08.006
-
Fucile, S. (2004). Ca2+ permeability of nicotinic acetylcholine receptors. Cell Calcium 35, 1-8. doi: 10.1016/j.ceca.2003.08.006
-
(2004)
Cell Calcium
, vol.35
, pp. 1-8
-
-
Fucile, S.1
-
51
-
-
0031033013
-
Characterization of recombinant human P2X4 receptor reveals pharmacological differences to the rat homologue
-
Garcia-Guzman, M., Soto, F., Gomez-Hernandez, J. M., Lund, P. E., and Stuhmer, W. (1997). Characterization of recombinant human P2X4 receptor reveals pharmacological differences to the rat homologue. Mol. Pharmacol. 51, 109-118.
-
(1997)
Mol. Pharmacol
, vol.51
, pp. 109-118
-
-
Garcia-Guzman, M.1
Soto, F.2
Gomez-Hernandez, J.M.3
Lund, P.E.4
Stuhmer, W.5
-
52
-
-
84863393008
-
Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis
-
doi: 10.1038/nm.2679
-
Gulbransen, B. D., Bashashati, M., Hirota, S. A., Gui, X., Roberts, J. A., MacDonald, J. A., et al. (2012). Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis. Nat. Med. 18, 600-604. doi: 10.1038/nm.2679
-
(2012)
Nat. Med
, vol.18
, pp. 600-604
-
-
Gulbransen, B.D.1
Bashashati, M.2
Hirota, S.A.3
Gui, X.4
Roberts, J.A.5
McDonald, J.A.6
-
53
-
-
0035980064
-
The first transmembrane domain of the P2X receptor subunit participates in the agonist-induced gating of the channel
-
doi: 10.1074/jbc.M104216200
-
Haines, W. R., Migita, K., Cox, J. A., Egan, T. M., and Voigt, M. M. (2001). The first transmembrane domain of the P2X receptor subunit participates in the agonist-induced gating of the channel. J. Biol. Chem. 276, 32793-32798. doi: 10.1074/jbc.M104216200
-
(2001)
J. Biol. Chem
, vol.276
, pp. 32793-32798
-
-
Haines, W.R.1
Migita, K.2
Cox, J.A.3
Egan, T.M.4
Voigt, M.M.5
-
54
-
-
84860785529
-
Molecular mechanism of ATP binding and ion channel activation in P2X receptors
-
doi: 10.1038/nature11010
-
Hattori, M., and Gouaux, E. (2012). Molecular mechanism of ATP binding and ion channel activation in P2X receptors. Nature 485, 207-212. doi: 10.1038/nature11010
-
(2012)
Nature
, vol.485
, pp. 207-212
-
-
Hattori, M.1
Gouaux, E.2
-
55
-
-
84885767038
-
Inter-and intrasubunit interactions between transmembrane helices in the open state of P2X receptor channels
-
doi: 10.1073/pnas.1311071110
-
Heymann, G., Dai, J., Li, M., Silberberg, S. D., Zhou, H. X., and Swartz, K. J. (2013). Inter-and intrasubunit interactions between transmembrane helices in the open state of P2X receptor channels. Proc. Natl. Acad. Sci. U.S.A. 110, E4045-E4054. doi: 10.1073/pnas.1311071110
-
(2013)
Proc. Natl. Acad. Sci. U.S. A
, vol.110
-
-
Heymann, G.1
Dai, J.2
Li, M.3
Silberberg, S.D.4
Zhou, H.X.5
Swartz, K.J.6
-
56
-
-
0003443746
-
-
3nd Edn. Sunderland, MA: Sinauer Associates
-
Hille, B. (2001). Ion Channels of Excitable Membranes, 3nd Edn. Sunderland, MA: Sinauer Associates, 441-574.
-
(2001)
Ion Channels of Excitable Membranes
, pp. 441-574
-
-
Hille, B.1
-
57
-
-
0032168179
-
The activation gate of a voltage-gated K+ channel can be trapped in the open state by an intersubunit metal bridge
-
doi: 10.1016/S0896-6273(00)80571-1
-
Holmgren, M., Shin, K. S., and Yellen, G. (1998). The activation gate of a voltage-gated K+ channel can be trapped in the open state by an intersubunit metal bridge. Neuron 21, 617-621. doi: 10.1016/S0896-6273(00)80571-1
-
(1998)
Neuron
, vol.21
, pp. 617-621
-
-
Holmgren, M.1
Shin, K.S.2
Yellen, G.3
-
58
-
-
0036400557
-
Voltage and concentration dependence of Ca(2+) permeability in recombinant glutamate receptor subtypes
-
doi: 10.1113/jphysiol.2001.012897
-
Jatzke, C., Watanabe, J., and Wollmuth, L. P. (2002). Voltage and concentration dependence of Ca(2+) permeability in recombinant glutamate receptor subtypes. J. Physiol. 538, 25-39. doi: 10.1113/jphysiol.2001.012897
-
(2002)
J. Physiol
, vol.538
, pp. 25-39
-
-
Jatzke, C.1
Watanabe, J.2
Wollmuth, L.P.3
-
59
-
-
0141864571
-
Subunit arrangement in P2X receptors
-
Jiang, L. H., Kim, M., Spelta, V., Bo, X., Surprenant, A., and North, R. A. (2003). Subunit arrangement in P2X receptors. J. Neurosci. 23, 8903-8910.
-
(2003)
J. Neurosci
, vol.23
, pp. 8903-8910
-
-
Jiang, L.H.1
Kim, M.2
Spelta, V.3
Bo, X.4
Surprenant, A.5
North, R.A.6
-
60
-
-
26844570488
-
N-methyl-D-glucamine and propidium dyes utilize different permeation pathways at rat P2X(7) receptors
-
doi: 10.1152/ajpcell.00253.2005
-
Jiang, L. H., Rassendren, F., Mackenzie, A., Zhang, Y. H., Surprenant, A., and North, R. A. (2005). N-methyl-D-glucamine and propidium dyes utilize different permeation pathways at rat P2X(7) receptors. Am. J. Physiol. Cell Physiol. 289, C1295-C1302. doi: 10.1152/ajpcell.00253.2005
-
(2005)
Am. J. Physiol. Cell Physiol
, vol.289
-
-
Jiang, L.H.1
Rassendren, F.2
McKenzie, A.3
Zhang, Y.H.4
Surprenant, A.5
North, R.A.6
-
61
-
-
0035805612
-
Amino acid residues involved in gating identified in the first membrane-spanning domain of the rat P2X(2) receptor
-
doi: 10.1074/jbc.M011327200
-
Jiang, L. H., Rassendren, F., Spelta, V., Surprenant, A., and North, R. A. (2001). Amino acid residues involved in gating identified in the first membrane-spanning domain of the rat P2X(2) receptor. J. Biol. Chem. 276, 14902-14908. doi: 10.1074/jbc.M011327200
-
(2001)
J. Biol. Chem
, vol.276
, pp. 14902-14908
-
-
Jiang, L.H.1
Rassendren, F.2
Spelta, V.3
Surprenant, A.4
North, R.A.5
-
62
-
-
77952373276
-
A putative extracellular salt bridge at the subunit interface contributes to the ion channel function of the ATP-gated P2X2 receptor
-
doi: 10.1074/jbc.M110.101980
-
Jiang, R., Martz, A., Gonin, S., Taly, A., de Carvalho, L. P., and Grutter, T. (2010). A putative extracellular salt bridge at the subunit interface contributes to the ion channel function of the ATP-gated P2X2 receptor. J. Biol. Chem. 285, 15805-15815. doi: 10.1074/jbc.M110.101980
-
(2010)
J. Biol. Chem
, vol.285
, pp. 15805-15815
-
-
Jiang, R.1
Martz, A.2
Gonin, S.3
Taly, A.4
de Carvalho, L.P.5
Grutter, T.6
-
63
-
-
84861526394
-
Molecular and functional properties of P2X receptors-recent progress and persisting challenges
-
doi: 10.1007/s11302-012-9314-7
-
Kaczmarek-Hajek, K., Lorinczi, E., Hausmann, R., and Nicke, A. (2012). Molecular and functional properties of P2X receptors-recent progress and persisting challenges. Purinergic Signal. 8, 375-417. doi: 10.1007/s11302-012-9314-7
-
(2012)
Purinergic Signal
, vol.8
, pp. 375-417
-
-
Kaczmarek-Hajek, K.1
Lorinczi, E.2
Hausmann, R.3
Nicke, A.4
-
64
-
-
67949117176
-
Crystal structure of the ATP-gated P2X(4) ion channel in the closed state
-
doi: 10.1038/nature08198
-
Kawate, T., Michel, J. C., Birdsong, W. T., and Gouaux, E. (2009). Crystal structure of the ATP-gated P2X(4) ion channel in the closed state. Nature 460, 592-598. doi: 10.1038/nature08198
-
(2009)
Nature
, vol.460
, pp. 592-598
-
-
Kawate, T.1
Michel, J.C.2
Birdsong, W.T.3
Gouaux, E.4
-
65
-
-
79958024000
-
Ion access pathway to the transmembrane pore in P2X receptor channels
-
doi: 10.1085/jgp.201010593
-
Kawate, T., Robertson, J. L., Li, M., Silberberg, S. D., and Swartz, K. J. (2011). Ion access pathway to the transmembrane pore in P2X receptor channels. J. Gen. Physiol. 137, 579-590. doi: 10.1085/jgp.201010593
-
(2011)
J. Gen. Physiol
, vol.137
, pp. 579-590
-
-
Kawate, T.1
Robertson, J.L.2
Li, M.3
Silberberg, S.D.4
Swartz, K.J.5
-
66
-
-
3543062342
-
Ligand-gated ion channels: Mechanisms underlying ion selectivity
-
doi: 10.1016/j.pbiomolbio.2003.09.002
-
Keramidas, A., Moorhouse, A. J., Schofield, P. R., and Barry, P. H. (2004). Ligand-gated ion channels: mechanisms underlying ion selectivity. Prog. Biophys. Mol. Biol. 86, 161-204. doi: 10.1016/j.pbiomolbio.2003.09.002
-
(2004)
Prog. Biophys. Mol. Biol
, vol.86
, pp. 161-204
-
-
Keramidas, A.1
Moorhouse, A.J.2
Schofield, P.R.3
Barry, P.H.4
-
67
-
-
0033366463
-
Neuronal P2X transmitter-gated cation channels change their ion selectivity in seconds
-
doi: 10.1038/7233
-
Khakh, B. S., Bao, X. R., Labarca, C., and Lester, H. A. (1999a). Neuronal P2X transmitter-gated cation channels change their ion selectivity in seconds. Nat. Neurosci. 2, 322-330. doi: 10.1038/7233
-
(1999)
Nat. Neurosci
, vol.2
, pp. 322-330
-
-
Khakh, B.S.1
Bao, X.R.2
Labarca, C.3
Lester, H.A.4
-
68
-
-
0033198189
-
Allosteric control of gating and kinetics at P2X(4) receptor channels
-
Khakh, B. S., Proctor, W. R., Dunwiddie, T. V., Labarca, C., and Lester, H. A. (1999b). Allosteric control of gating and kinetics at P2X(4) receptor channels. J. Neurosci. 19, 7289-7299.
-
(1999)
J. Neurosci
, vol.19
, pp. 7289-7299
-
-
Khakh, B.S.1
Proctor, W.R.2
Dunwiddie, T.V.3
Labarca, C.4
Lester, H.A.5
-
69
-
-
14044274324
-
Contribution of transmembrane regions to ATP-gated P2X2 channel permeability dynamics
-
doi: 10.1074/jbc.M411324200
-
Khakh, B. S., and Egan, T. M. (2005). Contribution of transmembrane regions to ATP-gated P2X2 channel permeability dynamics. J. Biol. Chem. 280, 6118-6129. doi: 10.1074/jbc.M411324200
-
(2005)
J. Biol. Chem
, vol.280
, pp. 6118-6129
-
-
Khakh, B.S.1
Egan, T.M.2
-
70
-
-
0031848216
-
ATP receptor-mediated enhancement of fast excitatory neurotransmitter release in the brain
-
Khakh, B. S., and Henderson, G. (1998). ATP receptor-mediated enhancement of fast excitatory neurotransmitter release in the brain. Mol. Pharmacol. 54, 372-378.
-
(1998)
Mol. Pharmacol
, vol.54
, pp. 372-378
-
-
Khakh, B.S.1
Henderson, G.2
-
71
-
-
0034601288
-
Modulation of fast synaptic transmission by presynaptic ligand-gated cation channels
-
doi: 10.1016/S0165-1838(00)00111-9
-
Khakh, B. S., and Henderson, G. (2000). Modulation of fast synaptic transmission by presynaptic ligand-gated cation channels. J. Auton. Nerv. Syst. 81, 110-121. doi: 10.1016/S0165-1838(00)00111-9
-
(2000)
J. Auton. Nerv. Syst
, vol.81
, pp. 110-121
-
-
Khakh, B.S.1
Henderson, G.2
-
72
-
-
0033180224
-
Dynamic selectivity filters in ion channels
-
doi: 10.1016/S0896-6273(01)80025-8
-
Khakh, B. S., and Lester, H. A. (1999). Dynamic selectivity filters in ion channels. Neuron 23, 653-658. doi: 10.1016/S0896-6273(01)80025-8
-
(1999)
Neuron
, vol.23
, pp. 653-658
-
-
Khakh, B.S.1
Lester, H.A.2
-
73
-
-
33746701380
-
P2X receptors as cell-surface ATP sensors in health and disease
-
doi: 10.1038/nature04886
-
Khakh, B. S., and North, R. A. (2006). P2X receptors as cell-surface ATP sensors in health and disease. Nature 442, 527-532. doi: 10.1038/nature04886
-
(2006)
Nature
, vol.442
, pp. 527-532
-
-
Khakh, B.S.1
North, R.A.2
-
74
-
-
0034214881
-
Coexpression of rat P2X2 and P2X6 subunits in Xenopus oocytes
-
King, B. F., Townsend-Nicholson, A., Wildman, S. S., Thomas, T., Spyer, K. M., and Burnstock, G. (2000). Coexpression of rat P2X2 and P2X6 subunits in Xenopus oocytes. J. Neurosci. 20, 4871-4877.
-
(2000)
J. Neurosci
, vol.20
, pp. 4871-4877
-
-
King, B.F.1
Townsend-Nicholson, A.2
Wildman, S.S.3
Thomas, T.4
Spyer, K.M.5
Burnstock, G.6
-
75
-
-
0033569461
-
Excitatory effect of P2X receptor activation on mesenteric afferent nerves in the anaesthetised rat
-
doi: 10.1111/j.1469-7793.1999.00551.x
-
Kirkup, A. J., Booth, C. E., Chessell, I. P., Humphrey, P. P., and Grundy, D. (1999). Excitatory effect of P2X receptor activation on mesenteric afferent nerves in the anaesthetised rat. J. Physiol. 520(Pt 2), 551-563. doi: 10.1111/j.1469-7793.1999.00551.x
-
(1999)
J. Physiol
, vol.520
, Issue.PART 2
, pp. 551-563
-
-
Kirkup, A.J.1
Booth, C.E.2
Chessell, I.P.3
Humphrey, P.P.4
Grundy, D.5
-
76
-
-
0034714006
-
Characteristics of P2X7 receptors from human B lymphocytes expressed in Xenopus oocytes
-
doi: 10.1016/S0005-2736(00)00245-5
-
Klapperstuck, M., Buttner, C., Bohm, T., Schmalzing, G., and Markwardt, F. (2000). Characteristics of P2X7 receptors from human B lymphocytes expressed in Xenopus oocytes. Biochim. Biophys. Acta. 1467, 444-456. doi: 10.1016/S0005-2736(00)00245-5
-
(2000)
Biochim. Biophys. Acta
, vol.1467
, pp. 444-456
-
-
Klapperstuck, M.1
Buttner, C.2
Bohm, T.3
Schmalzing, G.4
Markwardt, F.5
-
77
-
-
77951213527
-
Gated access to the pore of a P2X receptor: Structural implications for closed-open transitions
-
doi: 10.1074/jbc.M109.089185
-
Kracun, S., Chaptal, V., Abramson, J., and Khakh, B. S. (2010). Gated access to the pore of a P2X receptor: structural implications for closed-open transitions. J. Biol. Chem. 285, 10110-10121. doi: 10.1074/jbc.M109.089185
-
(2010)
J. Biol. Chem
, vol.285
, pp. 10110-10121
-
-
Kracun, S.1
Chaptal, V.2
Abramson, J.3
Khakh, B.S.4
-
78
-
-
0031030226
-
Atomic distance estimates from disulfides and high-affinity metal-binding sites in a K+ channel pore
-
doi: 10.1016/S0006-3495(97)78651-X
-
Krovetz, H. S., VanDongen, H. M., and VanDongen, A. M. (1997). Atomic distance estimates from disulfides and high-affinity metal-binding sites in a K+ channel pore. Biophys. J. 72, 117-126. doi: 10.1016/S0006-3495(97)78651-X
-
(1997)
Biophys. J
, vol.72
, pp. 117-126
-
-
Krovetz, H.S.1
VanDongen, H.M.2
VanDongen, A.M.3
-
79
-
-
0028941130
-
Side-chain accessibilities in the pore of a K+ channel probed by sulfhydryl-specific reagents after cysteine-scanning mutagenesis
-
doi: 10.1016/S0006-3495(95)80266-3
-
Kurz, L. L., Zuhlke, R. D., Zhang, H. J., and Joho, R. H. (1995). Side-chain accessibilities in the pore of a K+ channel probed by sulfhydryl-specific reagents after cysteine-scanning mutagenesis. Biophys. J. 68, 900-905. doi: 10.1016/S0006-3495(95)80266-3
-
(1995)
Biophys. J
, vol.68
, pp. 900-905
-
-
Kurz, L.L.1
Zuhlke, R.D.2
Zhang, H.J.3
Joho, R.H.4
-
80
-
-
84866327243
-
Structural changes during HCN channel gating defined by high affinity metal bridges
-
doi: 10.1085/jgp.201210838
-
Kwan, D. C., Prole, D. L., and Yellen, G. (2012). Structural changes during HCN channel gating defined by high affinity metal bridges. J. Gen. Physiol. 140, 279-291. doi: 10.1085/jgp.201210838
-
(2012)
J. Gen. Physiol
, vol.140
, pp. 279-291
-
-
Kwan, D.C.1
Prole, D.L.2
Yellen, G.3
-
81
-
-
0037144622
-
Evoked and spontaneous purinergic junctional Ca2+ transients (jCaTs) in rat small arteries
-
doi: 10.1161/01.RES.0000035060.98415.4B
-
Lamont, C., and Wier, W. G. (2002). Evoked and spontaneous purinergic junctional Ca2+ transients (jCaTs) in rat small arteries. Circ. Res. 91, 454-456. doi: 10.1161/01.RES.0000035060.98415.4B
-
(2002)
Circ. Res
, vol.91
, pp. 454-456
-
-
Lamont, C.1
Wier, W.G.2
-
82
-
-
0032032383
-
Sensory presynaptic and widespread somatodendritic immunolocalization of central ionotropic P2X ATP receptors
-
doi: 10.1016/S0306-4522(97)00365-5
-
Le, K. T., Villeneuve, P., Ramjaun, A. R., McPherson, P. S., Beaudet, A., and Seguela, P. (1998). Sensory presynaptic and widespread somatodendritic immunolocalization of central ionotropic P2X ATP receptors Neuroscience 83, 177-190. doi: 10.1016/S0306-4522(97)00365-5
-
(1998)
Neuroscience
, vol.83
, pp. 177-190
-
-
Le, K.T.1
Villeneuve, P.2
Ramjaun, A.R.3
McPherson, P.S.4
Beaudet, A.5
Seguela, P.6
-
83
-
-
0028982205
-
Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons
-
doi: 10.1038/377432a0
-
Lewis, C., Neidhart, S., Holy, C., North, R. A., Buell, G., and Surprenant, A. (1995). Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons Nature 377, 432-435. doi: 10.1038/377432a0
-
(1995)
Nature
, vol.377
, pp. 432-435
-
-
Lewis, C.1
Neidhart, S.2
Holy, C.3
North, R.A.4
Buell, G.5
Surprenant, A.6
-
84
-
-
79957733084
-
Activity-dependent targeting of TRPV1 with a pore-permeating capsaicin analog
-
doi: 10.1073/pnas.1018550108
-
Li, H., Wang, S., Chuang, A. Y., Cohen, B. E., and Chuang, H. H. (2011). Activity-dependent targeting of TRPV1 with a pore-permeating capsaicin analog. Proc. Natl. Acad. Sci. U.S.A. 108, 8497-8502. doi: 10.1073/pnas.1018550108
-
(2011)
Proc. Natl. Acad. Sci. U.S. A
, vol.108
, pp. 8497-8502
-
-
Li, H.1
Wang, S.2
Chuang, A.Y.3
Cohen, B.E.4
Chuang, H.H.5
-
85
-
-
48149111510
-
Gating the pore of P2X receptor channels
-
doi: 10.1038/nn.2151
-
Li, M., Chang, T. H., Silberberg, S. D., and Swartz, K. J. (2008). Gating the pore of P2X receptor channels. Nat. Neurosci. 11, 883-887. doi: 10.1038/nn.2151
-
(2008)
Nat. Neurosci
, vol.11
, pp. 883-887
-
-
Li, M.1
Chang, T.H.2
Silberberg, S.D.3
Swartz, K.J.4
-
86
-
-
84880308941
-
Pore-opening mechanism in trimeric P2X receptor channels
-
doi: 10.1038/ncomms1048
-
Li, M., Kawate, T., Silberberg, S. D., and Swartz, K. J. (2010). Pore-opening mechanism in trimeric P2X receptor channels. Nat. Commun. 1, 44. doi: 10.1038/ncomms1048
-
(2010)
Nat. Commun
, vol.1
, pp. 44
-
-
Li, M.1
Kawate, T.2
Silberberg, S.D.3
Swartz, K.J.4
-
87
-
-
0030709246
-
A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells
-
doi: 10.1074/jbc.272.47.29778
-
Lingueglia, E., de Weille, J. R., Bassilana, F., Heurteaux, C., Sakai, H., Waldmann, R., et al. (1997). A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells. J. Biol. Chem. 272, 29778-29783. doi: 10.1074/jbc.272.47.29778
-
(1997)
J. Biol. Chem
, vol.272
, pp. 29778-29783
-
-
Lingueglia, E.1
de Weille, J.R.2
Bassilana, F.3
Heurteaux, C.4
Sakai, H.5
Waldmann, R.6
-
88
-
-
0030795112
-
Gated access to the pore of a voltage-dependent K+ channel
-
doi: 10.1016/S0896-6273(00)80357-8
-
Liu, Y., Holmgren, M., Jurman, M. E., and Yellen, G. (1997). Gated access to the pore of a voltage-dependent K+ channel. Neuron 19, 175-184. doi: 10.1016/S0896-6273(00)80357-8
-
(1997)
Neuron
, vol.19
, pp. 175-184
-
-
Liu, Y.1
Holmgren, M.2
Jurman, M.E.3
Yellen, G.4
-
89
-
-
33846438625
-
Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex
-
doi: 10.1016/j.febslet.2006.12.056
-
Locovei, S., Scemes, E., Qiu, F., Spray, D. C., and Dahl, G. (2007). Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex. FEBS Lett. 581, 483-488. doi: 10.1016/j.febslet.2006.12.056
-
(2007)
FEBS Lett
, vol.581
, pp. 483-488
-
-
Locovei, S.1
Scemes, E.2
Qiu, F.3
Spray, D.C.4
Dahl, G.5
-
90
-
-
0028960949
-
Silver as a probe of pore-forming residues in a potassium channel
-
doi: 10.1126/science.7716526
-
Lu, Q., and Miller, C. (1995). Silver as a probe of pore-forming residues in a potassium channel. Science 268, 304-307. doi: 10.1126/science.7716526
-
(1995)
Science
, vol.268
, pp. 304-307
-
-
Lu, Q.1
Miller, C.2
-
91
-
-
84862615541
-
Pannexin 1 forms an anion-selective channel
-
doi: 10.1007/s00424-012-1077-z
-
Ma, W., Compan, V., Zheng, W., Martin, E., North, R. A., Verkhratsky, A., et al. (2012). Pannexin 1 forms an anion-selective channel. Pflugers Arch. 463, 585-592. doi: 10.1007/s00424-012-1077-z
-
(2012)
Pflugers Arch
, vol.463
, pp. 585-592
-
-
Ma, W.1
Compan, V.2
Zheng, W.3
Martin, E.4
North, R.A.5
Verkhratsky, A.6
-
92
-
-
0242657337
-
Potassium channels
-
doi: 10.1016/S0014-5793(03)01104-9
-
MacKinnon, R. (2003). Potassium channels. FEBS Lett. 555, 62-65. doi: 10.1016/S0014-5793(03)01104-9
-
(2003)
FEBS Lett
, vol.555
, pp. 62-65
-
-
McKinnon, R.1
-
93
-
-
0025743521
-
Conductance and kinetic properties of single nicotinic acetylcholine receptor channels in rat sympathetic neurones
-
Mathie, A., Cull-Candy, S. G., and Colquhoun, D. (1991). Conductance and kinetic properties of single nicotinic acetylcholine receptor channels in rat sympathetic neurones. J. Physiol. 439, 717-750.
-
(1991)
J. Physiol
, vol.439
, pp. 717-750
-
-
Mathie, A.1
Cull-Candy, S.G.2
Colquhoun, D.3
-
94
-
-
0035903169
-
Polar residues of the second transmembrane domain influence cation permeability of the ATP-gated P2X(2) receptor
-
doi: 10.1074/jbc.M103366200
-
Migita, K., Haines, W. R., Voigt, M. M., and Egan, T. M. (2001). Polar residues of the second transmembrane domain influence cation permeability of the ATP-gated P2X(2) receptor. J. Biol. Chem. 276, 30934-30941. doi: 10.1074/jbc.M103366200
-
(2001)
J. Biol. Chem
, vol.276
, pp. 30934-30941
-
-
Migita, K.1
Haines, W.R.2
Voigt, M.M.3
Egan, T.M.4
-
95
-
-
0028784222
-
The use of fura-2 for estimating Ca buffers and Ca fluxes
-
doi: 10.1016/0028-3908(95)00144-U
-
Neher, E. (1995). The use of fura-2 for estimating Ca buffers and Ca fluxes. Neuropharmacology 34, 1423-1442. doi: 10.1016/0028-3908(95)00144-U
-
(1995)
Neuropharmacology
, vol.34
, pp. 1423-1442
-
-
Neher, E.1
-
96
-
-
0032510957
-
Membrane topology of an ATP-gated ion channel (P2X receptor)
-
doi: 10.1074/jbc.273.24.15177
-
Newbolt, A., Stoop, R., Virginio, C., Surprenant, A., North, R. A., Buell, G., et al. (1998). Membrane topology of an ATP-gated ion channel (P2X receptor). J. Biol. Chem. 273, 15177-15182. doi: 10.1074/jbc.273.24.15177
-
(1998)
J. Biol. Chem
, vol.273
, pp. 15177-15182
-
-
Newbolt, A.1
Stoop, R.2
Virginio, C.3
Surprenant, A.4
North, R.A.5
Buell, G.6
-
97
-
-
0032089620
-
P2X1 and P2X3 receptors form stable trimers: A novel structural motif of ligand-gated ion channels
-
doi: 10.1093/emboj/17.11.3016
-
Nicke, A., Baumert, H. G., Rettinger, J., Eichele, A., Lambrecht, G., Mutschler, E., et al. (1998). P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels. Embo J. 17, 3016-3028. doi: 10.1093/emboj/17.11.3016
-
(1998)
Embo J
, vol.17
, pp. 3016-3028
-
-
Nicke, A.1
Baumert, H.G.2
Rettinger, J.3
Eichele, A.4
Lambrecht, G.5
Mutschler, E.6
-
98
-
-
70350012258
-
A functional P2X7 splice variant with an alternative transmembrane domain 1 escapes gene inactivation in P2X7 knock-out mice
-
doi: 10.1074/jbc.M109.033134
-
Nicke, A., Kuan, Y. H., Masin, M., Rettinger, J., Marquez-Klaka, B., Bender, O., et al. (2009). A functional P2X7 splice variant with an alternative transmembrane domain 1 escapes gene inactivation in P2X7 knock-out mice. J. Biol. Chem. 284, 25813-25822. doi: 10.1074/jbc.M109.033134
-
(2009)
J. Biol. Chem
, vol.284
, pp. 25813-25822
-
-
Nicke, A.1
Kuan, Y.H.2
Masin, M.3
Rettinger, J.4
Marquez-Klaka, B.5
Bender, O.6
-
99
-
-
0035961228
-
Stimulation of mouse cultured sympathetic neurons by uracil but not adenine
-
doi: 10.1016/S0306-4522(00)00547-9
-
Norenberg, W., Gobel, I., Meyer, A., Cox, S. L., Starke, K., and Trendelenburg, A. U. (2001). Stimulation of mouse cultured sympathetic neurons by uracil but not adenine nucleotides 103, 227-236. doi: 10.1016/S0306-4522(00)00547-9
-
(2001)
Nucleotides
, vol.103
, pp. 227-236
-
-
Norenberg, W.1
Gobel, I.2
Meyer, A.3
Cox, S.L.4
Starke, K.5
Trendelenburg, A.U.6
-
100
-
-
0036788971
-
Molecular physiology of P2X receptors
-
doi: 10.1152/physrev.00015.2002
-
North, R. A. (2002) Molecular physiology of P2X receptors. Physiol. Rev. 82, 1013-1067. doi: 10.1152/physrev.00015.2002
-
(2002)
Physiol. Rev
, vol.82
, pp. 1013-1067
-
-
North, R.A.1
-
101
-
-
84875426837
-
P2X receptors as drug targets
-
doi: 10.1124/mol.112.083758
-
North, R. A., and Jarvis, M. F. (2013). P2X receptors as drug targets. Mol. Pharmacol. 83, 759-769. doi: 10.1124/mol.112.083758
-
(2013)
Mol. Pharmacol
, vol.83
, pp. 759-769
-
-
North, R.A.1
Jarvis, M.F.2
-
102
-
-
0028303241
-
Differential activation of cation channels and non-selective pores by macrophage P2z purinergic receptors expressed in xenopus oocytes
-
Nuttle, L. C., and Dubyak, G. R. (1994). Differential activation of cation channels and non-selective pores by macrophage P2z purinergic receptors expressed in xenopus oocytes. J. Biol. Chem. 269, 13988-13996.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 13988-13996
-
-
Nuttle, L.C.1
Dubyak, G.R.2
-
103
-
-
0034662506
-
P2X7 receptors in Muller glial cells from the human retina
-
Pannicke, T., Fischer, W., Biedermann, B., Schadlich, H., Grosche, J., Faude, F., et al. (2000). P2X7 receptors in Muller glial cells from the human retina. J. Neurosci. 20, 5965-5972.
-
(2000)
J. Neurosci
, vol.20
, pp. 5965-5972
-
-
Pannicke, T.1
Fischer, W.2
Biedermann, B.3
Schadlich, H.4
Grosche, J.5
Faude, F.6
-
104
-
-
79958789017
-
Many ways to dilate the P2X7 receptor pore
-
doi: 10.1111/j.1476-5381.2011.01325.x
-
Pelegrin, P. (2011). Many ways to dilate the P2X7 receptor pore. Br. J. Pharmacol. 163, 908-911. doi: 10.1111/j.1476-5381.2011.01325.x
-
(2011)
Br. J. Pharmacol
, vol.163
, pp. 908-911
-
-
Pelegrin, P.1
-
105
-
-
33750473352
-
Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor
-
doi: 10.1038/sj.emboj.7601378
-
Pelegrin, P., and Surprenant, A. (2006). Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. EMBO J. 25, 5071-5082. doi: 10.1038/sj.emboj.7601378
-
(2006)
EMBO J
, vol.25
, pp. 5071-5082
-
-
Pelegrin, P.1
Surprenant, A.2
-
106
-
-
0031567594
-
P2X7 purinoceptor expression in Xenopus oocytes is not sufficient to produce a pore-forming P2Z-like phenotype
-
doi: 10.1016/S0014-5793(97)00700-X
-
Petrou, S., Ugur, M., Drummond, R. M., Singer, J. J., and Walsh, J. V. Jr. (1997). P2X7 purinoceptor expression in Xenopus oocytes is not sufficient to produce a pore-forming P2Z-like phenotype. FEBS Lett. 411, 339-345. doi: 10.1016/S0014-5793(97)00700-X
-
(1997)
FEBS Lett
, vol.411
, pp. 339-345
-
-
Petrou, S.1
Ugur, M.2
Drummond, R.M.3
Singer, J.J.4
Walsh Jr., J.V.5
-
107
-
-
84859141893
-
P2X7 receptor-pannexin 1 hemichannel association: Effect of extracellular calcium on membrane permeabilization
-
doi: 10.1007/s12031-011-9646-8
-
Poornima, V., Madhupriya, M., Kootar, S., Sujatha, G., Kumar, A., and Bera, A. K. (2012). P2X7 receptor-pannexin 1 hemichannel association: effect of extracellular calcium on membrane permeabilization. J. Mol. Neurosci. 46, 585-594. doi: 10.1007/s12031-011-9646-8
-
(2012)
J. Mol. Neurosci
, vol.46
, pp. 585-594
-
-
Poornima, V.1
Madhupriya, M.2
Kootar, S.3
Sujatha, G.4
Kumar, A.5
Bera, A.K.6
-
108
-
-
0037112377
-
Single-channel properties of native and cloned rat vanilloid receptors
-
doi: 10.1113/jphysiol.2002.016352
-
Premkumar, L. S., Agarwal, S., and Steffen, D. (2002). Single-channel properties of native and cloned rat vanilloid receptors. J. Physiol. 545, 107-117. doi: 10.1113/jphysiol.2002.016352
-
(2002)
J. Physiol
, vol.545
, pp. 107-117
-
-
Premkumar, L.S.1
Agarwal, S.2
Steffen, D.3
-
109
-
-
1442309855
-
Silberberg, Mechanism of ivermectin facilitation of human P2X4 receptor channels
-
doi: 10.1085/jgp.200308986
-
Priel, A., and Silberberg, S. D. (2004). Silberberg, Mechanism of ivermectin facilitation of human P2X4 receptor channels. J. Gen. Physiol. 123, 281-293. doi: 10.1085/jgp.200308986
-
(2004)
J. Gen. Physiol
, vol.123
, pp. 281-293
-
-
Priel, A.1
Silberberg, S.D.2
-
110
-
-
60849084461
-
A permeant regulating its permeation pore: Inhibition of pannexin 1 channels by ATP
-
doi: 10.1152/ajpcell.00433.2008
-
Qiu, F., and Dahl, G. (2009). A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP. Am. J. Physiol. Cell Physiol. 296, C250-C255. doi: 10.1152/ajpcell.00433.2008
-
(2009)
Am. J. Physiol. Cell Physiol
, vol.296
-
-
Qiu, F.1
Dahl, G.2
-
111
-
-
0030962404
-
Identification of amino acid residues contributing to the pore of a P2X receptor
-
doi: 10.1093/emboj/16.12.3446
-
Rassendren, F., Buell, G., Newbolt, A., North, R. A., and Surprenant, A. (1997). Identification of amino acid residues contributing to the pore of a P2X receptor. Embo. J. 16, 3446-3454. doi: 10.1093/emboj/16.12.3446
-
(1997)
Embo. J
, vol.16
, pp. 3446-3454
-
-
Rassendren, F.1
Buell, G.2
Newbolt, A.3
North, R.A.4
Surprenant, A.5
-
112
-
-
34047233727
-
Kinetics of P2X7 receptor-operated single channels currents
-
doi: 10.1529/biophysj.106.091413
-
Riedel, T., Lozinsky, I., Schmalzing, G., and Markwardt, F. (2007). Kinetics of P2X7 receptor-operated single channels currents. Biophys. J. 92, 2377-2391. doi: 10.1529/biophysj.106.091413
-
(2007)
Biophys. J
, vol.92
, pp. 2377-2391
-
-
Riedel, T.1
Lozinsky, I.2
Schmalzing, G.3
Markwardt, F.4
-
113
-
-
84858665860
-
Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel
-
doi: 10.1073/pnas.1201872109
-
Roberts, J. A., Allsopp, R. C., El Ajouz, S., Vial, C., Schmid, R., Young, M. T., et al. (2012a). Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel. Proc. Natl. Acad. Sci. U.S.A. 109, 4663-4667. doi: 10.1073/pnas.1201872109
-
(2012)
Proc. Natl. Acad. Sci. U.S. A
, vol.109
, pp. 4663-4667
-
-
Roberts, J.A.1
Allsopp, R.C.2
El Ajouz, S.3
Vial, C.4
Schmid, R.5
Young, M.T.6
-
114
-
-
84868652948
-
Mass spectrometry analysis of human P2X1 receptors; insight into phosphorylation, modelling and conformational changes
-
doi: 10.1111/jnc.12012
-
Roberts, J. A., Bottrill, A. R., Mistry, S., and Evans, R. J. (2012b). Mass spectrometry analysis of human P2X1 receptors; insight into phosphorylation, modelling and conformational changes. J. Neurochem. 123, 725-735. doi: 10.1111/jnc.12012
-
(2012)
J. Neurochem
, vol.123
, pp. 725-735
-
-
Roberts, J.A.1
Bottrill, A.R.2
Mistry, S.3
Evans, R.J.4
-
115
-
-
34247120710
-
Cysteine substitution mutants give structural insight and identify ATP binding and activation sites at P2X receptors
-
doi: 10.1523/JNEUROSCI.2310-06.2007
-
Roberts, J. A., and Evans, R. J. (2007). Cysteine substitution mutants give structural insight and identify ATP binding and activation sites at P2X receptors. J. Neurosci. 27, 4072-4082. doi: 10.1523/JNEUROSCI.2310-06.2007
-
(2007)
J. Neurosci
, vol.27
, pp. 4072-4082
-
-
Roberts, J.A.1
Evans, R.J.2
-
116
-
-
33745760891
-
Molecular properties of P2X receptors
-
doi: 10.1007/s00424-006-0073-6
-
Roberts, J. A., Vial, C., Digby, H. R., Agboh, K. C., Wen, H., Atterbury-Thomas, A., et al. (2006). Molecular properties of P2X receptors. Pflugers Arch. 452, 486-500. doi: 10.1007/s00424-006-0073-6
-
(2006)
Pflugers Arch
, vol.452
, pp. 486-500
-
-
Roberts, J.A.1
Vial, C.2
Digby, H.R.3
Agboh, K.C.4
Wen, H.5
Atterbury-Thomas, A.6
-
117
-
-
0028814237
-
Comparison of quantitative calcium flux through NMDA, ATP, and ACh receptor channels
-
doi: 10.1016/S0006-3495(95)80211-0
-
Rogers, M., and Dani, J. A. (1995). Comparison of quantitative calcium flux through NMDA, ATP, and ACh receptor channels. Biophys. J. 68, 501-506. doi: 10.1016/S0006-3495(95)80211-0
-
(1995)
Biophys. J
, vol.68
, pp. 501-506
-
-
Rogers, M.1
Dani, J.A.2
-
118
-
-
8844263063
-
Activation of ureter nociceptors by exogenous and endogenous ATP in guinea pig
-
doi: 10.1016/j.neuropharm.2004.08.003
-
Rong, W., and Burnstock, G. (2004). Activation of ureter nociceptors by exogenous and endogenous ATP in guinea pig. Neuropharmacology 47, 1093-1101. doi: 10.1016/j.neuropharm.2004.08.003
-
(2004)
Neuropharmacology
, vol.47
, pp. 1093-1101
-
-
Rong, W.1
Burnstock, G.2
-
119
-
-
20544431525
-
Ion conduction and selectivity in K(+) channels
-
doi: 10.1146/annurev.biophys.34.040204.144655
-
Roux, B. (2005). Ion conduction and selectivity in K(+) channels. Annu. Rev. Biophys. Biomol. Struct. 34, 153-171. doi: 10.1146/annurev.biophys.34.040204.144655
-
(2005)
Annu. Rev. Biophys. Biomol. Struct
, vol.34
, pp. 153-171
-
-
Roux, B.1
-
120
-
-
0035007786
-
Genomic structure, developmental distribution and functional properties of the chicken P2X(5) receptor
-
doi: 10.1046/j.1471-4159.2001.00348.x
-
Ruppelt, A., Ma, W., Borchardt, K., Silberberg, S. D., and Soto, F. (2001). Genomic structure, developmental distribution and functional properties of the chicken P2X(5) receptor. J. Neurochem. 77, 1256-1265. doi: 10.1046/j.1471-4159.2001.00348.x
-
(2001)
J. Neurochem
, vol.77
, pp. 1256-1265
-
-
Ruppelt, A.1
Ma, W.2
Borchardt, K.3
Silberberg, S.D.4
Soto, F.5
-
121
-
-
33847345548
-
Acidic amino acids impart enhanced Ca2+ permeability and flux in two members of the ATP-gated P2X receptor family
-
doi: 10.1085/jgp.200609677
-
Samways, D. S., and Egan, T. M. (2007). Acidic amino acids impart enhanced Ca2+ permeability and flux in two members of the ATP-gated P2X receptor family. J. Gen. Physiol. 129, 245-256. doi: 10.1085/jgp.200609677
-
(2007)
J. Gen. Physiol
, vol.129
, pp. 245-256
-
-
Samways, D.S.1
Egan, T.M.2
-
122
-
-
80054756055
-
Calcium-dependent decrease in the single-channel conductance of TRPV1
-
doi: 10.1007/s00424-011-1013-7
-
Samways, D. S., and Egan, T. M. (2011). Calcium-dependent decrease in the single-channel conductance of TRPV1. Pflugers Arch. 462, 681-691. doi: 10.1007/s00424-011-1013-7
-
(2011)
Pflugers Arch
, vol.462
, pp. 681-691
-
-
Samways, D.S.1
Egan, T.M.2
-
123
-
-
80051959810
-
Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors)
-
doi: 10.1073/pnas.1017550108
-
Samways, D. S., Khakh, B. S., Dutertre, S., and Egan, T. M. (2011). Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors). Proc. Natl. Acad. Sci. U.S.A. 108, 13800-13805. doi: 10.1073/pnas.1017550108
-
(2011)
Proc. Natl. Acad. Sci. U.S. A
, vol.108
, pp. 13800-13805
-
-
Samways, D.S.1
Khakh, B.S.2
Dutertre, S.3
Egan, T.M.4
-
124
-
-
41949101239
-
On the role of the first transmembrane domain in cation permeability and flux of the ATP-gated P2X2 receptor
-
doi: 10.1074/jbc.M708713200
-
Samways, D. S., Migita, K., Li, Z., and Egan, T. M. (2008a). On the role of the first transmembrane domain in cation permeability and flux of the ATP-gated P2X2 receptor. J. Biol. Chem. 283, 5110-5117. doi: 10.1074/jbc.M708713200
-
(2008)
J. Biol. Chem
, vol.283
, pp. 5110-5117
-
-
Samways, D.S.1
Migita, K.2
Li, Z.3
Egan, T.M.4
-
125
-
-
57649120783
-
Tunable calcium current through TRPV1 receptor channels
-
doi: 10.1074/jbc.C800131200
-
Samways, D. S., Khakh, B. S., and Egan, T. M. (2008b). Tunable calcium current through TRPV1 receptor channels. J. Biol. Chem. 283, 31274-31278. doi: 10.1074/jbc.C800131200
-
(2008)
J. Biol. Chem
, vol.283
, pp. 31274-31278
-
-
Samways, D.S.1
Khakh, B.S.2
Egan, T.M.3
-
126
-
-
84857718067
-
Allosteric modulation of Ca2+ flux in a ligand-gated cation channel (P2X4) by actions on lateral portals
-
doi: 10.1074/jbc.M111.322461
-
Samways, D. S., Khakh, B. S., and Egan, T. M. (2012). Allosteric modulation of Ca2+ flux in a ligand-gated cation channel (P2X4) by actions on lateral portals. J. Biol. Chem. 287, 7594-7602. doi: 10.1074/jbc.M111.322461
-
(2012)
J. Biol. Chem
, vol.287
, pp. 7594-7602
-
-
Samways, D.S.1
Khakh, B.S.2
Egan, T.M.3
-
127
-
-
0038170314
-
Permeation and selectivity in calcium channels
-
doi: 10.1146/annurev.physiol.65.092101.142345
-
Sather, W. A., and McCleskey, E. W. (2003). Permeation and selectivity in calcium channels. Annu. Rev. Physiol. 65, 133-159. doi: 10.1146/annurev.physiol.65.092101.142345
-
(2003)
Annu. Rev. Physiol
, vol.65
, pp. 133-159
-
-
Sather, W.A.1
McCleskey, E.W.2
-
128
-
-
55649094970
-
ATP-induced P2X7-associated uptake of large molecules involves distinct mechanisms for cations and anions in macrophages
-
doi: 10.1242/jcs.029991
-
Schachter, J., Motta, A. P., de Souza Zamorano, A., da Silva-Souza, H. A., Guimaraes, M. Z., and Persechini, P. M. (2008). ATP-induced P2X7-associated uptake of large molecules involves distinct mechanisms for cations and anions in macrophages. J. Cell Sci. 121, 3261-3270. doi: 10.1242/jcs.029991
-
(2008)
J. Cell Sci
, vol.121
, pp. 3261-3270
-
-
Schachter, J.1
Motta, A.P.2
de Souza Zamorano, A.3
da Silva-Souza, H.A.4
Guimaraes, M.Z.5
Persechini, P.M.6
-
129
-
-
75049085160
-
On the origin of ion selectivity in the Cys-loop receptor family
-
doi: 10.1007/s12031-009-9260-1
-
Sine, S. M., Wang, H. L., Hansen, S., and Taylor, P. (2010). On the origin of ion selectivity in the Cys-loop receptor family. J. Mol. Neurosci. 40, 70-76. doi: 10.1007/s12031-009-9260-1
-
(2010)
J. Mol. Neurosci
, vol.40
, pp. 70-76
-
-
Sine, S.M.1
Wang, H.L.2
Hansen, S.3
Taylor, P.4
-
130
-
-
4444230523
-
Mechanisms underlying postjunctional synergism between responses of the vas deferens to noradrenaline and ATP
-
doi: 10.1016/j.ejphar.2004.07.055
-
Smith, N. C., and Burnstock, G. (2004). Mechanisms underlying postjunctional synergism between responses of the vas deferens to noradrenaline and ATP. Eur. J. Pharmacol. 498, 241-248. doi: 10.1016/j.ejphar.2004.07.055
-
(2004)
Eur. J. Pharmacol
, vol.498
, pp. 241-248
-
-
Smith, N.C.1
Burnstock, G.2
-
131
-
-
18344382709
-
A strategy for mapping and neutralizing conformational immunogenic sites on protein therapeutics
-
doi: 10.1002/1615-9861(200203)2:3%3C271::AID-PROT271%3E3.0.CO;2-W
-
Spencer, D. I., Robson, L., Purdy, D., Whitelegg, N. R., Michael, N. P., Bhatia, J., et al. (2002). A strategy for mapping and neutralizing conformational immunogenic sites on protein therapeutics. Proteomics 2, 271-279. doi: 10.1002/1615-9861(200203)2:3%3C271::AID-PROT271%3E3.0.CO;2-W
-
(2002)
Proteomics
, vol.2
, pp. 271-279
-
-
Spencer, D.I.1
Robson, L.2
Purdy, D.3
Whitelegg, N.R.4
Michael, N.P.5
Bhatia, J.6
-
132
-
-
0023664593
-
ATP4-permeabilizes the plasma membrane of mouse macrophages to fluorescent dyes
-
Steinberg, T. H., Newman, A. S., Swanson, J. A., and Silverstein, S. C. (1987). ATP4-permeabilizes the plasma membrane of mouse macrophages to fluorescent dyes. J. Biol. Chem. 262, 8884-8888.
-
(1987)
J. Biol. Chem
, vol.262
, pp. 8884-8888
-
-
Steinberg, T.H.1
Newman, A.S.2
Swanson, J.A.3
Silverstein, S.C.4
-
133
-
-
0027099647
-
Single-channel conductances of NMDA receptors expressed from cloned cDNAs: Comparison with native receptors
-
doi: 10.1098/rspb.1992.0159
-
Stern, P., Behe, P., Schoepfer, R., and Colquhoun, D. (1992). Single-channel conductances of NMDA receptors expressed from cloned cDNAs: comparison with native receptors. Proc. Biol. Sci. 250, 271-277. doi: 10.1098/rspb.1992.0159
-
(1992)
Proc. Biol. Sci
, vol.250
, pp. 271-277
-
-
Stern, P.1
Behe, P.2
Schoepfer, R.3
Colquhoun, D.4
-
134
-
-
0032705299
-
Contribution of individual subunits to the multimeric P2X(2) receptor: Estimates based on methanethiosulfonate block at T336C
-
Stoop, R., Thomas, S., Rassendren, F., Kawashima, E., Buell, G., Surprenant, A., et al. (1999). Contribution of individual subunits to the multimeric P2X(2) receptor: estimates based on methanethiosulfonate block at T336C. Mol. Pharmacol. 56, 973-981.
-
(1999)
Mol. Pharmacol
, vol.56
, pp. 973-981
-
-
Stoop, R.1
Thomas, S.2
Rassendren, F.3
Kawashima, E.4
Buell, G.5
Surprenant, A.6
-
135
-
-
0029665112
-
The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)
-
doi: 10.1126/science.272.5262.735
-
Surprenant, A., Rassendren, F., Kawashima, E., North, R. A., and Buell, G. (1996). The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science 272, 735-738. doi: 10.1126/science.272.5262.735
-
(1996)
Science
, vol.272
, pp. 735-738
-
-
Surprenant, A.1
Rassendren, F.2
Kawashima, E.3
North, R.A.4
Buell, G.5
-
136
-
-
0033121302
-
Ca2+-permeable P2X receptor channels in cultured rat retinal ganglion cells
-
Taschenberger, H., Juttner, R., and Grantyn, R. (1999). Ca2+-permeable P2X receptor channels in cultured rat retinal ganglion cells. J. Neurosci. 19, 3353-3366.
-
(1999)
J. Neurosci
, vol.19
, pp. 3353-3366
-
-
Taschenberger, H.1
Juttner, R.2
Grantyn, R.3
-
137
-
-
0023820529
-
Characterisation of the ATP4-receptor that mediates permeabilisation of rat mast cells
-
doi: 10.1016/0014-2999(88)90628-0
-
Tatham, P. E., Cusack, N. J., and Gomperts, B. D. (1988). Characterisation of the ATP4-receptor that mediates permeabilisation of rat mast cells. Eur. J. Pharmacol. 147, 13-21. doi: 10.1016/0014-2999(88)90628-0
-
(1988)
Eur. J. Pharmacol
, vol.147
, pp. 13-21
-
-
Tatham, P.E.1
Cusack, N.J.2
Gomperts, B.D.3
-
138
-
-
0025278255
-
Permeation of both cations and anions through a single class of ATP-activated ion channels in developing chick skeletal muscle
-
doi: 10.1085/jgp.95.4.569
-
Thomas, S. A., and Hume, R. I. (1990). Permeation of both cations and anions through a single class of ATP-activated ion channels in developing chick skeletal muscle. J. Gen. Physiol. 95, 569-590. doi: 10.1085/jgp.95.4.569
-
(1990)
J. Gen. Physiol
, vol.95
, pp. 569-590
-
-
Thomas, S.A.1
Hume, R.I.2
-
139
-
-
0032552895
-
N-Linked glycosylation is essential for the functional expression of the recombinant P2X2 receptor
-
doi: 10.1021/bi981209g
-
Torres, G. E., Egan, T. M., and Voigt, M. M. (1998a). N-Linked glycosylation is essential for the functional expression of the recombinant P2X2 receptor. Biochemistry 37, 14845-14851. doi: 10.1021/bi981209g
-
(1998)
Biochemistry
, vol.37
, pp. 14845-14851
-
-
Torres, G.E.1
Egan, T.M.2
Voigt, M.M.3
-
140
-
-
0032549559
-
Topological analysis of the ATP-gated ionotropic [correction of ionotrophic] P2X2 receptor subunit
-
doi: 10.1016/S0014-5793(98)00179-3
-
Torres, G. E., Egan, T. M., and Voigt, M. M. (1998b). Topological analysis of the ATP-gated ionotropic [correction of ionotrophic] P2X2 receptor subunit. FEBS Lett. 425, 19-23. doi: 10.1016/S0014-5793(98)00179-3
-
(1998)
FEBS Lett
, vol.425
, pp. 19-23
-
-
Torres, G.E.1
Egan, T.M.2
Voigt, M.M.3
-
141
-
-
0032217176
-
Co-expression of P2X1 and P2X5 receptor subunits reveals a novel ATP-gated ion channel
-
Torres, G. E., Haines, W. R., Egan, T. M., and Voigt, M. M. (1998c). Co-expression of P2X1 and P2X5 receptor subunits reveals a novel ATP-gated ion channel. Mol. Pharmacol. 54, 989-993.
-
(1998)
Mol. Pharmacol
, vol.54
, pp. 989-993
-
-
Torres, G.E.1
Haines, W.R.2
Egan, T.M.3
Voigt, M.M.4
-
142
-
-
0033525891
-
Hetero-oligomeric assembly of P2X receptor subunits. Specificities exist with regard to possible partners
-
doi: 10.1074/jbc.274.10.6653
-
Torres, G. E., Egan, T. M., and Voigt, M. M. (1999). Hetero-oligomeric assembly of P2X receptor subunits. Specificities exist with regard to possible partners. J. Biol. Chem. 274, 6653-6659. doi: 10.1074/jbc.274.10.6653
-
(1999)
J. Biol. Chem
, vol.274
, pp. 6653-6659
-
-
Torres, G.E.1
Egan, T.M.2
Voigt, M.M.3
-
143
-
-
77950201361
-
P2X4 receptors in activated C8-B4 cells of cerebellar microglial origin
-
doi: 10.1085/jgp.200910336
-
Toulme, E., Garcia, A., Samways, D., Egan, T. M., Carson, M. J., and Khakh, B. S. (2010). P2X4 receptors in activated C8-B4 cells of cerebellar microglial origin. J. Gen. Physiol. 135, 333-353. doi: 10.1085/jgp.200910336
-
(2010)
J. Gen. Physiol
, vol.135
, pp. 333-353
-
-
Toulme, E.1
Garcia, A.2
Samways, D.3
Egan, T.M.4
Carson, M.J.5
Khakh, B.S.6
-
144
-
-
77952363301
-
Glutamate receptor ion channels: Structure, regulation, and function
-
doi: 10.1124/pr.109.002451
-
Traynelis, S. F., Wollmuth, L. P., McBain, C. J., Menniti, F. S., Vance, K. M., Ogden, K. K., et al. (2010). Glutamate receptor ion channels: structure, regulation, and function. Pharmacol. Rev. 62, 405-496. doi: 10.1124/pr.109.002451
-
(2010)
Pharmacol. Rev
, vol.62
, pp. 405-496
-
-
Traynelis, S.F.1
Wollmuth, L.P.2
McBain, C.J.3
Menniti, F.S.4
Vance, K.M.5
Ogden, K.K.6
-
145
-
-
0028030797
-
A new class of ligand-gated ion channel defined by P2x receptor for extracellular ATP
-
doi: 10.1038/371516a0
-
Valera, S., Hussy, N., Evans, R. J., Adami, N., North, R. A., Surprenant, A., et al. (1994). A new class of ligand-gated ion channel defined by P2x receptor for extracellular ATP. Nature 371, 516-519. doi: 10.1038/371516a0
-
(1994)
Nature
, vol.371
, pp. 516-519
-
-
Valera, S.1
Hussy, N.2
Evans, R.J.3
Adami, N.4
North, R.A.5
Surprenant, A.6
-
146
-
-
0029564426
-
Characterization and chromosomal localization of a human P2X receptor from the urinary bladder
-
Valera, S., Talabot, F., Evans, R. J., Gos, A., Antonarakis, S. E., Morris, M. A., et al. (1995). Characterization and chromosomal localization of a human P2X receptor from the urinary bladder. Receptors Channels 3, 283-289.
-
(1995)
Receptors Channels
, vol.3
, pp. 283-289
-
-
Valera, S.1
Talabot, F.2
Evans, R.J.3
Gos, A.4
Antonarakis, S.E.5
Morris, M.A.6
-
147
-
-
0028945477
-
Dimensions of the narrow portion of a recombinant NMDA receptor channel
-
doi: 10.1016/S0006-3495(95)80263-8
-
Villarroel, A., Burnashev, N., and Sakmann, B. (1995). Dimensions of the narrow portion of a recombinant NMDA receptor channel. Biophys. J. 68, 866-875. doi: 10.1016/S0006-3495(95)80263-8
-
(1995)
Biophys. J
, vol.68
, pp. 866-875
-
-
Villarroel, A.1
Burnashev, N.2
Sakmann, B.3
-
148
-
-
0030661885
-
Effects of divalent cations, protons and calmidazolium at the rat P2X7 receptor
-
doi: 10.1016/S0028-3908(97)00141-X
-
Virginio, C., Church, D., North, R. A., and Surprenant, A. (1997). Effects of divalent cations, protons and calmidazolium at the rat P2X7 receptor. Neuropharmacology 36, 1285-1294. doi: 10.1016/S0028-3908(97)00141-X
-
(1997)
Neuropharmacology
, vol.36
, pp. 1285-1294
-
-
Virginio, C.1
Church, D.2
North, R.A.3
Surprenant, A.4
-
149
-
-
0033360313
-
Pore dilation of neuronal P2X receptor channels
-
doi: 10.1038/7225
-
Virginio, C., MacKenzie, A., Rassendren, F. A., North, R. A., and Surprenant, A. (1999a). Pore dilation of neuronal P2X receptor channels. Nat. Neurosci. 2, 315-321. doi: 10.1038/7225
-
(1999)
Nat. Neurosci
, vol.2
, pp. 315-321
-
-
Virginio, C.1
McKenzie, A.2
Rassendren, F.A.3
North, R.A.4
Surprenant, A.5
-
150
-
-
0033198510
-
Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X7 receptor
-
doi: 10.1111/j.1469-7793.1999.0335m.x
-
Virginio, C., MacKenzie, A., North, R. A., and Surprenant, A. (1999b). Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X7 receptor. J. Physiol. 519(Pt 2), 335-346. doi: 10.1111/j.1469-7793.1999.0335m.x
-
(1999)
J. Physiol
, vol.519
, Issue.PART 2
, pp. 335-346
-
-
Virginio, C.1
McKenzie, A.2
North, R.A.3
Surprenant, A.4
-
151
-
-
0032127817
-
Calcium permeability and block at homomeric and heteromeric P2X2 and P2X3 receptors, and P2X receptors in rat nodose neurones
-
doi: 10.1111/j.1469-7793.1998.027bz.x
-
Virginio, C., North, R. A., and Surprenant, A. (1998). Calcium permeability and block at homomeric and heteromeric P2X2 and P2X3 receptors, and P2X receptors in rat nodose neurones. J. Physiol. 510(Pt 1), 27-35. doi: 10.1111/j.1469-7793.1998.027bz.x
-
(1998)
J. Physiol
, vol.510
, Issue.PART 1
, pp. 27-35
-
-
Virginio, C.1
North, R.A.2
Surprenant, A.3
-
152
-
-
84869045095
-
P2X7 receptors: Channels, pores and more
-
doi: 10.2174/187152712803581137
-
Volonte, C., Apolloni, S., Skaper, S. D., and Burnstock, G. (2012). P2X7 receptors: channels, pores and more. CNS neurol. Disord. Drug Targets 11, 705-721. doi: 10.2174/187152712803581137
-
(2012)
CNS neurol. Disord. Drug Targets
, vol.11
, pp. 705-721
-
-
Volonte, C.1
Apolloni, S.2
Skaper, S.D.3
Burnstock, G.4
-
153
-
-
0032976359
-
Role of action potentials and calcium influx in ATP-and UDP-induced noradrenaline release from rat cultured sympathetic neurones
-
doi: 10.1007/PL00005362
-
von Kugelgen, I., Norenberg, W., Meyer, A., Illes, P., and Starke, K. (1999). Role of action potentials and calcium influx in ATP-and UDP-induced noradrenaline release from rat cultured sympathetic neurones. Naunyn. Schmiedebergs. Arch. Pharmacol. 359, 360-369. doi: 10.1007/PL00005362
-
(1999)
Naunyn. Schmiedebergs. Arch. Pharmacol
, vol.359
, pp. 360-369
-
-
von Kugelgen, I.1
Norenberg, W.2
Meyer, A.3
Illes, P.4
Starke, K.5
-
154
-
-
0027338244
-
The ATP4-receptor-operated channel (P2Z class) of human lymphocytes allows Ba2+ and ethidium+ uptake: Inhibition of fluxes by suramin
-
doi: 10.1006/abbi.1993.1392
-
Wiley, J. S., Chen, R., and Jamieson, G. P. (1993). The ATP4-receptor-operated channel (P2Z class) of human lymphocytes allows Ba2+ and ethidium+ uptake: inhibition of fluxes by suramin. Arch. Biochem. Biophys. 305, 54-60. doi: 10.1006/abbi.1993.1392
-
(1993)
Arch. Biochem. Biophys
, vol.305
, pp. 54-60
-
-
Wiley, J.S.1
Chen, R.2
Jamieson, G.P.3
-
155
-
-
84867112397
-
Splice variants of the P2X7 receptor reveal differential agonist dependence and functional coupling with pannexin-1
-
doi: 10.1242/jcs.099374
-
Xu, X. J., Boumechache, M., Robinson, L. E., Marschall, V., Gorecki, D. C., Masin, M., et al. (2012). Splice variants of the P2X7 receptor reveal differential agonist dependence and functional coupling with pannexin-1. J. Cell Sci. 125, 3776-3789. doi: 10.1242/jcs.099374
-
(2012)
J. Cell Sci
, vol.125
, pp. 3776-3789
-
-
Xu, X.J.1
Boumechache, M.2
Robinson, L.E.3
Marschall, V.4
Gorecki, D.C.5
Masin, M.6
-
156
-
-
59449086148
-
The P2X7 receptor channel pore dilates under physiological ion conditions
-
doi: 10.1085/jgp.200810059
-
Yan, Z., Li, S., Liang, Z., Tomic, M., and Stojilkovic, S. S. (2008). The P2X7 receptor channel pore dilates under physiological ion conditions. J. Gen. Physiol. 132, 563-573. doi: 10.1085/jgp.200810059
-
(2008)
J. Gen. Physiol
, vol.132
, pp. 563-573
-
-
Yan, Z.1
Li, S.2
Liang, Z.3
Tomic, M.4
Stojilkovic, S.S.5
-
157
-
-
84877773919
-
Influences of membrane mimetic environments on membrane protein structures
-
doi: 10.1146/annurev-biophys-083012-130326
-
Zhou, H. X., and Cross, T. A. (2013). Influences of membrane mimetic environments on membrane protein structures. Annu. Rev. Biophys. 42, 361-392. doi: 10.1146/annurev-biophys-083012-130326
-
(2013)
Annu. Rev. Biophys
, vol.42
, pp. 361-392
-
-
Zhou, H.X.1
Cross, T.A.2
|