Distinct ATP receptors on pain-sensing and stretch-sensing neurons

Nature

Volumn 387, Issue 6632, 1997, Pages 505-508

  Cook, Sean P ^a   Vulchanova, Lucy ^b   Hargreaves, Kenneth M ^b   Elde, Robert ^b   McCleskey, Edwin W ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ION CHANNEL;

ARTICLE; NOCICEPTION; PAIN RECEPTOR; PATHOGENESIS; PRIORITY JOURNAL; TISSUE INJURY;

ACTION POTENTIALS; ADENOSINE TRIPHOSPHATE; ANIMALS; CARBOCYANINES; CELL LINE; CULTURE TECHNIQUES; DENTAL PULP; FLUORESCENT DYES; HUMANS; MALE; MECHANORECEPTORS; MEMBRANE POTENTIALS; MUSCLES; NEURONS; NEURONS, AFFERENT; NOCICEPTORS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P2; RECOMBINANT PROTEINS;

EID: 0030922667     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/387505a0     Document Type: Article

References (31)

1. Burnstock, G. A unifying purinergic hypothesis for the initiation of pain. Lancet 347, 1604-1605 (1996).
2. Kennedy, C & Leff, P. Painful connection for ATP. Nature 377, 285-386 (1995).
3. Bleehen, T. & Keele, C. A. Observations on the algogenic actions of adenosine compounds on the human blister base preparation. Pain 3, 367-377 (1977).
4. Bleehen, T., Hobbiger, F. & Keele, C. A. Identification of algogenic substances in human erythrocytes. J. Physiol. 262, 131-149 (1976).
5. Jahr, C. E. & Jessel, T. M. ATP excites a subpopulation of rat dorsal horn neurones. Nature 304, 730-733 (1983).
6. Krishtal, O. A., Marchenko, S. M. & Obukhov, A. G. Cationic channels activated by extracellular ATP in rat sensory neurons. Neuroscience 27, 995-1000 (1988).
7. Bean, B. P. ATP-activated channels in rat and bullfrog sensory neurons: concentration dependence and kinetics. J. Neurosci. 10, 1-10 (1990).
8. Chen, C.-C. et al. A P2X purinoceptor expressed by a subset of sensory neurons. Nature 377, 428-431 (1995).
9. Lewis, C. et al. Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons. Nature 377, 432-435 (1995).
10. Lawson, S. N. in Sensory Neurons (ed. Scott, S. A.) 27-59 (Oxford Univ. Press, Oxford, 1992).
11. Willis, W. D. & Coggeshall, R. E. in Sensory Mechanisms of the Spinal Cord 1-49 (Plenum, New York, 1978).
12. Edwall, L. & Olgart, L. A new technique for recording of intradental sensory nerve activity in man. Pain 3, 121-125 (1977).
13. Ahlquist, M. L., Edwall, L., Franzen, O. G. & Haegerstam, G. A. T. Perception of pulpal pain as a function of intradental nerve activity. Pain 19, 353-366 (1984).
14. Anderson, D. J. & Matthews, B. Osmotic stimulation of human dentine and the distribution of dental pain thresholds. Archs Oral Biol. 12, 417-426 (1967).
15. Ahlquist, M., Franzen, O., Edwall, L., Fors, U. & Haegerstam, G. in Advances in Pain Research and Therapy Vol. 9 (ed. Fields, H. L.) 351-359 (Raven, New York, 1985).
16. Taddese, A., Nah, S. Y. & McCleskey, E. W. Selective opioid inhibition of small nociceptive neurons. Science 270, 1366-1369 (1995).
17. Jyvasjarvi, E. & Kniffki, K.-D. Cold stimulation of teeth: A comparison between the responses of cat intradental Aδ and C fibres and human sensation. J. Physiol. 391, 193-207 (1987).
18. Narhi, M., Yamamoto, H., Ngassapa, D. & Hirvonen, T. The neurophysiological basis and the role of inflammatory reactions in dentine hypersensitivity. Archs Oral Biol. 39, 23a-30s (1994).
19. Cody, F. W. J., Lee, R. W. H. & Taylor, A. A functional analysis of the components of the mesencephalic nucleus of the fifth nerve in the cat. J. Physiol. 226, 249-261 (1972).
20. Corbin, K. B. & Harrison, F. Function of mesencephalic root of fifth cranial nerve. J. Neurophysiol. 3, 425-435 (1940).
21. Holton, P. The liberation of adenosine triphosphate on antidromic stimulation of sensory nerves. J. Physiol. 145, 494-504 (1959).
22. Khahk, B. S., Humphrey, P. P. A. & Henderson, G. ATP-gated cation channels (P2X purinoceptors) in trigeminal mesencephalic nucleus neurones of the rat. J. Physiol. 498, 709-715 (1997).
23. Valera, S. et al. A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATP. Nature 371, 516-519 (1994).
24. Collo, G. et al. Cloning of P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels. J. Neurosci. 16, 2495-2507 (1996).
25. Vulchanova, L. et al. Differential distribution of two ATP-gated ion channels (P2X receptors) determined by immunocytochemistry. Proc. Natl Acad. Sci. USA 93, 8063-8067 (1996).
26. Brake, A. J., Wagenbach, M. J. & Julius, D. New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor. Nature 371, 519-523 (1994).
27. Nakamura, F. & Strittmatter, S. M. P2Y1 purinergic receptors in sensory neurons: Contribution to touch-induced impulse generation. Proc. Natl. Acad. Sci. USA 93, 10465-10470 (1996).
28. Phillis, J. W. & Kirkpatrick, J. R. The actions of adenosine and various nucleosides and nucleotides on the isolated toad spinal cord. Gen. Pharmacol. 9, 239-247 (1978).
29. Lester, R. A., Tong, G. & Jahr, C. E. Interactions between the glycine and glutamate bindings sites of the NMDA receptor. J. Neurosci. 13, 1088-1096 (1993).
30. Arvidsson, U. et al. Distribution and targeting of a mu-opioid receptor (MOR1) in brain and spinal cord. J. Neurosci. 15, 3328-3341 (1995).
31. Abercrombie, M. Estimation of nuclear population from microtome sections. Anat. Rec. 94, 239-247 (1946).