Single channel properties of ATP-gated cation channels (P2X receptors) heterologously expressed in Chinese hamster ovary cells

Neuroscience Letters

Volumn 212, Issue 3, 1996, Pages 212-214

  Evans, R J ^a,b  

^a GLAXOSMITHKLINE   (United States)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Ion channels; P2X receptors; Purinergic

Indexed keywords

ADENOSINE TRIPHOSPHATE; CATION CHANNEL; PURINE RECEPTOR; RECEPTOR SUBTYPE;

ANIMAL CELL; ARTICLE; CHINESE HAMSTER; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FEMALE; GENETIC TRANSFECTION; NONHUMAN; OVARY CELL; PATCH CLAMP; PRIORITY JOURNAL;

EID: 0030593493     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(96)12804-4     Document Type: Article

References (13)

1. [1] Surprenant, A., Buell, G. and North, R.A., P2X receptors bring new structure to ligand gated ion channels, Trends Neurosci., 18 (1995) 224-229.
2. [2] Vincent, P., Cationic channels sensitive to extracellular ATP in rat lacrimal cells, J. Physiol., 449 (1992) 313-331.
3. [3] Fieber, L. and Adams, D.J., Adenosine triphosphate-evoked currents in cultured neurones dissociated from rat parasympathetic cardiac ganglia, J. Physiol. 434 (1991) 239-256.
4. [4] Evans, R.J., Lewis, C., Buell, G., North, R.A. and Surprenant, A., Pharmacological characterisation of heterologously expressed ATP-gated cation channels P2X-purinoceptors, Mol. Pharmacol. 48 (1995) 178-183.
5. [5] Brake, A.J., Wagenbach, M.J. and Julius, D., A new structural motif for ligand-gated ion channels defined by ionotropic ATP receptor, Nature, 371 (1994) 519-523.
6. 3 receptor subunits can account for ATP-gated currents in sensory neurones, Nature, 377 (1995) 432-435.
7. [7] Buell, G., Lewis, C., Collo, G., North, R.A. and Surprenant, A., An antagonist-insensitive P2X receptor in epithelia and brain, EMBO J., 15 (1996) 55-62.
8. 2+-permeable channels in rat pheochromocytoma (PC12) cells, J. Neurosci., 11 (1991) 3984-3990.
9. [9] Nakazawa, K. and Matsuki, N., Adenosine triphosphate-activated inward current in isolated smooth muscle cells from rat vas deferens, Pflüegers Arch., 409 (1987) 644-646.
10. 2+ ions, J. Neurophysiol., 73 (1995) 312-319.
11. 6 receptors and the distribution and properties of an extended family of ATP-gated ion channels, J. Neurosci. 16 (1996) 2495-2507.
12. [12] Bean, B.P., Williams, C.A. and Ceelen, P.W., ATP-activated channels in rat and bullfrog sensory neurons: current voltage relation and single-channel behaviour, J. Neurosci., 10 (1990) 11-19.
13. [13] Krishtal, O.A., Marchenko, S.M. and Obukhov, A.G., Cationic channels activated by extracellular ATP in rat sensory neurons, Neuroscience, 27 (1988) 996-1000.