Contribution of residues in second transmembrane domain of ASIC1a protein to ion selectivity

Journal of Biological Chemistry

Volumn 287, Issue 16, 2012, Pages 12927-12934

  Carattino, Marcelo D ^a   Della Vecchia, Margaret C ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID-SENSING ION CHANNELS; CENTRAL NERVOUS SYSTEMS; COORDINATION SITES; CYSTEINE SUBSTITUTIONS; EXTRACELLULAR; ION PERMEATION; ION SELECTIVITY; METHANETHIOSULFONATE; MOLECULAR SIEVING; POSITIVELY CHARGED; RELATIVE PERMEABILITY; SECOND TRANSMEMBRANE DOMAIN; TRANSMEMBRANES;

ACTIVATION ANALYSIS; AMINO ACIDS; BIOPHYSICS; CELL MEMBRANES; CESIUM; ENZYME ACTIVITY; IONS;

CESIUM COMPOUNDS;

ACID SENSING ION CHANNEL; ACID SENSING ION CHANNEL 1A; ALANINE; CESIUM; CYSTEINE; LITHIUM ION; METHANETHIOSULFONATE; POTASSIUM ION; RUBIDIUM; SODIUM ION; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; FEMALE; ION PERMEABILITY; ION TRANSPORT; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN STRUCTURE; SECOND TRANSMEMBRANE DOMAIN; SIGNAL TRANSDUCTION; SURFACE CHARGE; XENOPUS LAEVIS;

AMILORIDE; AMINO ACID SEQUENCE; ANIMALS; CATIONS; CELL MEMBRANE; FEMALE; ION CHANNEL GATING; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NERVE TISSUE PROTEINS; OOCYTES; PROTEIN STRUCTURE, TERTIARY; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 84859757951     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.329284     Document Type: Article

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