Effects of divalent cations, protons and calmidazolium at the rat P2X7 receptor

Neuropharmacology

Volumn 36, Issue 9, 1997, Pages 1285-1294

  Virginio, Caterina ^a   Church, Dennis ^a   North, R Alan ^a   Surprenant, Annmarie ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Cell permeabilization; Channel modulation; Electrophysiology; Fluorescence imaging; Ionotropic receptor; YO PRO dye uptake

Indexed keywords

CALMIDAZOLIUM; DIVALENT CATION; ION CHANNEL; PROTON; PURINE P2 RECEPTOR;

ANIMAL CELL; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CELL MEMBRANE PERMEABILITY; CHANNEL GATING; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030661885     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(97)00141-X     Document Type: Review

References (49)

1. Adams D. J., Dwyer T. M. and Hille B. (1980) The permeability of endplate channels to monovalent and divalent metal cations. Journal of General Physiology 75: 493-510.
2. Albuquerque E. X., Pereira E. F., Castro N. G., Alkondon M., Reinhardt S., Schroder H. and Maelicke A. (1995) Nicotinic receptor function in the mammalian central nervous system. Annals of the New York Academy of Science 757: 48-72.
3. Bean B. P. (1992) Pharmacology and electrophysiology of ATP-activated ion channels. Trends in Pharmacological Science 13: 87-90.
4. Bennett J. P., Cockcroft S. and Gomperts B. D. (1981) Rat mast cells permeabilized with ATP secrete histamine in response to calcium ions buffered in the micromolar range. Journal of Physiology 317: 335-345.
5. Brake A. J., Wagenbach M. J. and Julius D. (1994) New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor. Nature 371: 519-523.
6. Buell G., Collo G. and Rassendren F. (1996) P2X receptors: an emerging channel family. European Journal of Neuroscience 8: 2221-2228.
7. Clay J. R. (1995) Asymmetric modulation and blockade of the delayed rectifier in squid giant axons by divalent cations. Biophysical Journal 69: 1773-1779.
8. 2+ potentiates ATP-activated current in rat sympathetic neurons. Pflugers Archives 424: 152-158.
9. Cockcroft S. and Gomperts B. D. 1979b ATP induces nucleotide permeability in rat mast cells. Nature 279: 541-542.
10. 2+ antagonists. American Journal of Physiology 253: C162-170.
11. Evans R. J., Lewis C., Virginio C., Lundstrom K., Buell G., Surprenant A. and North R. A. (1996) Ionic permeability of, and divalent cation effects on, two ATP-gated cation channels (P2X receptors) expressed in mammalian cells. Journal of Physiology 497: 413-422.
12. Evans R. J. and Surprenant A. (1996) P2X receptors in autonomic and sensory neurons. Seminars in Neuroscience 8: 217-223.
13. Fenwick E. M., Marty A. and Neher E. (1982) A patch-clamp study of bovine chromaffin cells and of their sensitivity to acetylcholine. Journal of Physiology 331: 577-597.
14. Fieber L. A. and Adams D. J. (1991) Acetylcholine-evoked currents in cultured neurones dissociated from rat parasympathetic cardiac ganglia. Journal of Physiology 434: 215-237.
15. Heppel L. E., Weisman G. A. and Friedberg I. (1985) Permeabilization of transformed cells in culture by external ATP. Journal of Membrane Biology 86: 189-196.
16. Hickman S. E., El Khoury J., Greenberg S., Schieren I. and Silverstein S. C. (1994) P2Z adenosine triphosphate receptor activity in cultured human monocyte-derived macrophages. Blood 84: 2452-2456.
17. Hille, B. (1992) Ionic Channels of Excitable Membranes, second edition. Sinauer Associates, Sunderland, MA, U.S.A..
18. Karoor V., Shih M., Tholanikunnel B. and Malbon C. C. (1996) Regulating expression and function of G-protein-linked receptors. Progress in Neurobiology 48: 555-568.
19. Kawajiri S. and Dingledine R. (1993) Multiple structural determinants of voltage-dependent magnesium block in recombinant NMDA receptors. Neuropharmacology 32: 1203-1211.
20. King B. F., Ziganshina L. E., Pintor J. and Burnstock G. (1996) Full sensitivity of P2X2 purinoceptor to ATP revealed by changing extracellular pH. British Journal of Pharmacology 117: 1371-1373.
21. Kleene S. J. (1994) Inhibition of olfactory cyclic nucleotide-activated current by calmodulin antagonists. British Journal of Pharmacology 111: 469-472.
22. Klockner U. and Isenberg G. (1987) Calmodulin antagonists depress calcium and potassium currents in ventricular and vascular myocytes. American Journal of Physiology 253: H1601-1611.
23. 2+ permeable AMPA and NMDA receptor channels in basket cells of rat hippocampal dentate gyrus. Journal of Physiology 485: 383-402.
24. 3 receptors. In Ligand-and Voltage-gated Ion Channels (North, R. A.), pp. 177-212. CRC Press, Roca Baton, FL, U.S.A.
25. 3 receptor subunits can account for ATP-gated currents in sensory neurones. Nature 377: 432-434.
26. 2+ potentiates excitatory action of ATP on mammalian neurons. Proceedings of the National Academy of Science of the U.S.A. 90: 8264-8267.
27. 2+ in rat nodose ganglion neurons. Journal of Neurophysiology 76: 3048-3058.
28. 2+ potently enhances ATP-activated current in rat nodose ganglion neurons. Neuroscience Letters 219: 45-48.
29. 2+ decreases the agonist affinity of the receptor. Journal of Neurophysiology 77: 3391-3395.
30. Liu J. P. (1996) Protein kinase C and its substrates. Molecular Cellular Endocrinology 116: 1-29.
31. Ma J. and Coronado R. (1988) Heterogeneity of conductance states in calcium channels of skeletal muscle. Biophysical Journal 53: 387-395.
32. MacDonald R. L. and Olsen R. W. (1994) GABAA receptor channels. Annual Review in Neuroscience 17: 569-602.
33. Mayer M. L. and Westbrook G. (1987) Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones. Journal of Physiology 394: 501-527.
34. McBain C. J. and Mayer M. L. (1994) N-methyl-D-aspartic acid receptor structure and function. Physiological Review 74: 723-760.
35. Nakazawa K. and Hess P. (1993) Block by calcium of ATP-activated channels in pheochromocytoma cells. Journal of General Physiology 101: 377-392.
36. North R. A. (1996) Families of ion channels with two hydrophobic segments. Current Opinions in Cell Biology 8: 474-483.
37. Nuttle L. C. and Dubyak G. R. (1994) Differential activation of cation channels and non-selective pores by macrophage P2Z purinergic receptors expressed in Xenopus oocytes. Journal of Biological Chemistry 269: 13988-13996.
38. + RNA from murine macrophages. Molecular Pharmacology 44: 93-101.
39. 7. Journal of Biological Chemistry 272: 5482-5486.
40. Rassendren F., Buell G., Newbolt A., North R. A. and Surprenant A. 1997b Identification of amino acid residues contributing to the pore of a P2X receptor. EMBO Journal 16: 101-109.
41. Rogers M. and Dani J. A. (1995) Comparison of quantitative calcium flux through NMDA, ATP and ACh receptor channels. Biophysical Journal 68: 501-506.
42. Seguela P., Haghighi A., Soghomonian J. -J. and Cooper E. (1996) A novel neuronal P2X ATP receptor ion channel with widespread distribution in the brain. Journal of Neuroscience 16: 448-455.
43. Smart T. G., Xie X. and Krishek B. J. (1994) Modulation of inhibitory and excitatory amino acid receptor ion channels by zinc. Progress in Neurobiology 42: 393-441.
44. Soto F., Garcia-Guzman M., Gomez-Hernandez, Holmann M., Karschin C. and Stuhumer W. (1996) P2Xα4: an ATP-activated ionotropic receptor cloned from rat brain. Proceedings of the National Academy of Science of the U.S.A. 93: 3684-3688.
45. 4- permeabilizes the plasma membrane of mouse macrophages to fluorescent dyes. Journal of Biological Chemistry 262: 8884-8888.
46. Stoop, R., Surprenant, A. and North, R. A. (1997) Different sensitivities to pH of ATP-induced currents at four cloned P2X receptors. Journal of Neurophysiology (in press).
47. Surprenant A., Buell G. and North R. A. (1995) P2X receptor brings new structure to ligand-gated ion channels. Trends in Neuroscience 18: 224-229.
48. 7). Science 272: 735-738.
49. Tatham P. E. R. and Lindau M. (1990) ATP-induced pore formation in the plasma membrane of rat peritoneal mast cells. Journal of General Physiology 95: 459-476.