메뉴 건너뛰기




Volumn 19, Issue 17, 1999, Pages 7289-7299

Allosteric control of gating and kinetics at P2X4 receptor channels

Author keywords

Allosteric; ATP; Ion channel; Ivermectin; Modulation; P2X; Purinoceptor

Indexed keywords

ADENOSINE TRIPHOSPHATE; CATION CHANNEL; IVERMECTIN;

EID: 0033198189     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-17-07289.1999     Document Type: Article
Times cited : (264)

References (56)
  • 1
    • 0030612295 scopus 로고    scopus 로고
    • ATP P2X receptors mediate fast synaptic transmission in the dorsal horn of the rat spinal cord
    • Bardoni R, Goldstein PA, Lee CJ, Gu JG, MacDermott AB (1997) ATP P2X receptors mediate fast synaptic transmission in the dorsal horn of the rat spinal cord. J Neurosci 17:5297-5304.
    • (1997) J Neurosci , vol.17 , pp. 5297-5304
    • Bardoni, R.1    Goldstein, P.A.2    Lee, C.J.3    Gu, J.G.4    Macdermott, A.B.5
  • 2
    • 0028875979 scopus 로고
    • A P2X purinoceptor cDNA conferring a novel pharmacological profile
    • Bo X, Zhang Y, Nassar M, Burnstock G, Schoepfer R (1995) A P2X purinoceptor cDNA conferring a novel pharmacological profile. FEBS Lett 375:129-133.
    • (1995) FEBS Lett , vol.375 , pp. 129-133
    • Bo, X.1    Zhang, Y.2    Nassar, M.3    Burnstock, G.4    Schoepfer, R.5
  • 3
    • 0029671045 scopus 로고    scopus 로고
    • An antagonist-insensitive P2X receptor expressed in epithelia and brain
    • Buell G, Lewis C, Collo G, North RA, Surprenant A (1996) An antagonist-insensitive P2X receptor expressed in epithelia and brain. EMBO J 15:55-62.
    • (1996) EMBO J , vol.15 , pp. 55-62
    • Buell, G.1    Lewis, C.2    Collo, G.3    North, R.A.4    Surprenant, A.5
  • 4
    • 0015393308 scopus 로고
    • Purinergic nerves
    • Burnstock G (1972) Purinergic nerves. Pharmacol Rev 24:509-581.
    • (1972) Pharmacol Rev , vol.24 , pp. 509-581
    • Burnstock, G.1
  • 5
    • 0032215090 scopus 로고    scopus 로고
    • Allosteric receptors after 30 years
    • Changeux JP, Edelstein SJ (1998) Allosteric receptors after 30 years. Neuron 21:959-980.
    • (1998) Neuron , vol.21 , pp. 959-980
    • Changeux, J.P.1    Edelstein, S.J.2
  • 7
    • 0029665752 scopus 로고    scopus 로고
    • Cloning of P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels
    • Collo G, North RA, Kawashima E, Merlo-Pich E, Neidhart S, Surprenant A, Buell G (1996) Cloning of P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels. J Neurosci 16:2495-2507.
    • (1996) J Neurosci , vol.16 , pp. 2495-2507
    • Collo, G.1    North, R.A.2    Kawashima, E.3    Merlo-Pich, E.4    Neidhart, S.5    Surprenant, A.6    Buell, G.7
  • 9
    • 0032199006 scopus 로고    scopus 로고
    • Binding, gating, affinity and efficacy: The interpretation of structure-activity relationships for agonists and of the effects of mutating receptors
    • Colquhoun D (1998) Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors. Br J Pharmacol 125:924-947.
    • (1998) Br J Pharmacol , vol.125 , pp. 924-947
    • Colquhoun, D.1
  • 11
    • 0032532939 scopus 로고    scopus 로고
    • 2+ by speeding recovery of P2X receptors from desensitization
    • 2+ by speeding recovery of P2X receptors from desensitization. J Neurosci 18:9238-9244.
    • (1998) J Neurosci , vol.18 , pp. 9238-9244
    • Cook, S.P.1    Rodland, K.D.2    McCleskey, E.W.3
  • 13
    • 0030875738 scopus 로고    scopus 로고
    • Adenine nucleotides undergo rapid, quantitative conversion to adenosine in the extracellular space in rat hippocampus
    • Dunwiddie TV, Diao L, Proctor WR (1997) Adenine nucleotides undergo rapid, quantitative conversion to adenosine in the extracellular space in rat hippocampus. J Neurosci 17:7673-7682.
    • (1997) J Neurosci , vol.17 , pp. 7673-7682
    • Dunwiddie, T.V.1    Diao, L.2    Proctor, W.R.3
  • 14
    • 0026648857 scopus 로고
    • ATP receptor-mediated synaptic currents in the central nervous system
    • Edwards FA, Gibb AJ, Colquhoun D (1992) ATP receptor-mediated synaptic currents in the central nervous system. Nature 359:144-147.
    • (1992) Nature , vol.359 , pp. 144-147
    • Edwards, F.A.1    Gibb, A.J.2    Colquhoun, D.3
  • 15
    • 0026771094 scopus 로고
    • ATP mediates fast synaptic transmission in mammalian neurons
    • Evans RJ, Derkach V, Surprenant A (1992) ATP mediates fast synaptic transmission in mammalian neurons. Nature 357:503-505.
    • (1992) Nature , vol.357 , pp. 503-505
    • Evans, R.J.1    Derkach, V.2    Surprenant, A.3
  • 16
    • 0029955763 scopus 로고    scopus 로고
    • Ionic permeability of, and divalent cation effects on, two ATP-gated cation channels (P2X receptors) expressed in mammalian cells
    • Evans RJ, Lewis C, Virginio C, Lundstrom K, Buell G, Surprenant A, North RA (1996) Ionic permeability of, and divalent cation effects on, two ATP-gated cation channels (P2X receptors) expressed in mammalian cells. J Physiol (Lond) 497:413-422.
    • (1996) J Physiol (Lond) , vol.497 , pp. 413-422
    • Evans, R.J.1    Lewis, C.2    Virginio, C.3    Lundstrom, K.4    Buell, G.5    Surprenant, A.6    North, R.A.7
  • 17
    • 0026708417 scopus 로고
    • The chemistry and pharmacology of avermectins
    • Fisher MH, Mrozik H (1992) The chemistry and pharmacology of avermectins. Annu Rev Pharmacol Toxicol 32:537-553.
    • (1992) Annu Rev Pharmacol Toxicol , vol.32 , pp. 537-553
    • Fisher, M.H.1    Mrozik, H.2
  • 18
    • 0032520135 scopus 로고    scopus 로고
    • Acetylcholine activates an α-bungarotoxin-sensitive nicotinic current in rat hippocampal interneurons, but not pyramidal cells
    • Frazier CJ, Rollins YD, Breese CR, Leonard S, Freedman R, Dunwiddie TV (1998a) Acetylcholine activates an α-bungarotoxin-sensitive nicotinic current in rat hippocampal interneurons, but not pyramidal cells. J Neurosci 18:1187-1195.
    • (1998) J Neurosci , vol.18 , pp. 1187-1195
    • Frazier, C.J.1    Rollins, Y.D.2    Breese, C.R.3    Leonard, S.4    Freedman, R.5    Dunwiddie, T.V.6
  • 19
    • 0032531893 scopus 로고    scopus 로고
    • Synaptic potentials mediated via α-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal interneurons
    • Frazier CJ, Buhler AV, Weiner JL, Dunwiddie TV (1998b) Synaptic potentials mediated via α-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal interneurons. J Neurosci 18:8228-8235.
    • (1998) J Neurosci , vol.18 , pp. 8228-8235
    • Frazier, C.J.1    Buhler, A.V.2    Weiner, J.L.3    Dunwiddie, T.V.4
  • 20
    • 0030671405 scopus 로고    scopus 로고
    • Activation of ATP P2X receptors elicits glutamate release from sensory neuron synapses
    • Gu JG, MacDermott AB (1997) Activation of ATP P2X receptors elicits glutamate release from sensory neuron synapses. Nature 389:749-753.
    • (1997) Nature , vol.389 , pp. 749-753
    • Gu, J.G.1    Macdermott, A.B.2
  • 22
    • 0033363371 scopus 로고    scopus 로고
    • Synaptic corelease of ATP and GABA in cultured spinal neurons
    • Jo Y-H, Schlichter R (1999) Synaptic corelease of ATP and GABA in cultured spinal neurons. Nat Neurosci 2:241-245.
    • (1999) Nat Neurosci , vol.2 , pp. 241-245
    • Jo, Y.-H.1    Schlichter, R.2
  • 23
    • 0031848216 scopus 로고    scopus 로고
    • ATP receptor-mediated enhancement of fast excitatory neurotransmitter release in the brain
    • Khakh BS, Henderson G (1998a) ATP receptor-mediated enhancement of fast excitatory neurotransmitter release in the brain. Mol Pharmacol 54:372-378.
    • (1998) Mol Pharmacol , vol.54 , pp. 372-378
    • Khakh, B.S.1    Henderson, G.2
  • 24
    • 0032143908 scopus 로고    scopus 로고
    • h) in neurones of the trigeminal mesencephalic nucleus of the rat
    • h) in neurones of the trigeminal mesencephalic nucleus of the rat. J Physiol (Lond) 510:695-704.
    • (1998) J Physiol (Lond) , vol.510 , pp. 695-704
    • Khakh, B.S.1    Henderson, G.2
  • 25
    • 0028986090 scopus 로고
    • Electrophysiological properties of P2X-purinoceptors in rat superior cervical, nodose and guinea-pig coeliac neurones
    • Khakh BS, Humphrey PP, Surprenant A (1995a) Electrophysiological properties of P2X-purinoceptors in rat superior cervical, nodose and guinea-pig coeliac neurones. J Physiol (Lond) 484:385-395.
    • (1995) J Physiol (Lond) , vol.484 , pp. 385-395
    • Khakh, B.S.1    Humphrey, P.P.2    Surprenant, A.3
  • 26
    • 0028989393 scopus 로고
    • A study on P2X purinoceptors mediating the electrophysiological and contractile effects of purine nucleotides in rat vas deferens
    • Khakh BS, Surprenant A, Humphrey PP (1995b) A study on P2X purinoceptors mediating the electrophysiological and contractile effects of purine nucleotides in rat vas deferens. Br J Pharmacol 115:177-185.
    • (1995) Br J Pharmacol , vol.115 , pp. 177-185
    • Khakh, B.S.1    Surprenant, A.2    Humphrey, P.P.3
  • 27
    • 0031058152 scopus 로고    scopus 로고
    • ATP-gated cation channels (P2X purinoceptors) in trigeminal mesencephalic nucleus neurons of the rat
    • Khakh BS, Humphrey PP, Henderson G (1997) ATP-gated cation channels (P2X purinoceptors) in trigeminal mesencephalic nucleus neurons of the rat. J Physiol (Lond) 498:709-715.
    • (1997) J Physiol (Lond) , vol.498 , pp. 709-715
    • Khakh, B.S.1    Humphrey, P.P.2    Henderson, G.3
  • 28
    • 0033366463 scopus 로고    scopus 로고
    • Neuronal P2X receptor-transmitter-gated cation channels change their ion selectivity in seconds
    • Khakh B, Bao X, Labarca C, Lester H (1999) Neuronal P2X receptor-transmitter-gated cation channels change their ion selectivity in seconds. Nat Neurosci 2:322-330.
    • (1999) Nat Neurosci , vol.2 , pp. 322-330
    • Khakh, B.1    Bao, X.2    Labarca, C.3    Lester, H.4
  • 29
    • 0030807573 scopus 로고    scopus 로고
    • Effects of extracellular pH on agonism and antagonism at a recombinant P2X2 receptor
    • King BF, Wildman SS, Ziganshina LE, Pintor J, Burnstock G (1997) Effects of extracellular pH on agonism and antagonism at a recombinant P2X2 receptor. Br J Pharmacol 121:1445-1453.
    • (1997) Br J Pharmacol , vol.121 , pp. 1445-1453
    • King, B.F.1    Wildman, S.S.2    Ziganshina, L.E.3    Pintor, J.4    Burnstock, G.5
  • 31
    • 0028174057 scopus 로고
    • Effect of ivermectin on gamma-aminobutyric acid-induced chloride currents in mouse hippocampal embryonic neurones
    • Krusek J, Zemkova H (1994) Effect of ivermectin on gamma-aminobutyric acid-induced chloride currents in mouse hippocampal embryonic neurones. Eur J Pharmacol 259:121-128.
    • (1994) Eur J Pharmacol , vol.259 , pp. 121-128
    • Krusek, J.1    Zemkova, H.2
  • 32
    • 0032529842 scopus 로고    scopus 로고
    • Central P2X4 and P2X6 channel subunits coassemble into a novel heteromeric ATP receptor
    • Le KT, Babinski K, Séguéla P (1998a) Central P2X4 and P2X6 channel subunits coassemble into a novel heteromeric ATP receptor. J Neurosci 18:7152-7159.
    • (1998) J Neurosci , vol.18 , pp. 7152-7159
    • Le, K.T.1    Babinski, K.2    Séguéla, P.3
  • 33
    • 0032032383 scopus 로고    scopus 로고
    • Sensory presynaptic and widespread somatodendritic immunolocalization of central ionotropic P2X ATP receptors
    • Le KT, Villeneuve P, Ramjaun AR, McPherson PS, Beaudet A, Seguela P (1998b) Sensory presynaptic and widespread somatodendritic immunolocalization of central ionotropic P2X ATP receptors. Neuroscience 83:177-190.
    • (1998) Neuroscience , vol.83 , pp. 177-190
    • Le, K.T.1    Villeneuve, P.2    Ramjaun, A.R.3    McPherson, P.S.4    Beaudet, A.5    Seguela, P.6
  • 34
    • 0028982205 scopus 로고
    • Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons
    • Lewis C, Neidhart S, Holy C, North RA, Buell G, Surprenant A (1995) Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons [see comments]. Nature 377:432-435.
    • (1995) Nature , vol.377 , pp. 432-435
    • Lewis, C.1    Neidhart, S.2    Holy, C.3    North, R.A.4    Buell, G.5    Surprenant, A.6
  • 35
    • 0030967839 scopus 로고    scopus 로고
    • Cyclic nucleotide-gated channels: Structural basis of ligand efficacy and allosteric modulation
    • Li J, Zagotta WN, Lester HA (1997) Cyclic nucleotide-gated channels: structural basis of ligand efficacy and allosteric modulation. Q Rev Biophys 30:177-193.
    • (1997) Q Rev Biophys , vol.30 , pp. 177-193
    • Li, J.1    Zagotta, W.N.2    Lester, H.A.3
  • 36
    • 0032534964 scopus 로고    scopus 로고
    • Enhancement of neurotransmitter release induced by brain-derived neurotrophic factor in cultured hippocampal neurons
    • Li YX, Zhang Y, Lester HA, Schuman EM, Davidson N (1998) Enhancement of neurotransmitter release induced by brain-derived neurotrophic factor in cultured hippocampal neurons. J Neurosci 18:10231-10240.
    • (1998) J Neurosci , vol.18 , pp. 10231-10240
    • Li, Y.X.1    Zhang, Y.2    Lester, H.A.3    Schuman, E.M.4    Davidson, N.5
  • 37
    • 0030614993 scopus 로고    scopus 로고
    • Radiolabeling of the rat P2X4 purinoceptor: Evidence for allosteric interactions of purinoceptor antagonists and monovalent cations with P2X purinoceptors
    • Michel AD, Miller KJ, Lundstrom K, Buell GN, Humphrey PP (1997) Radiolabeling of the rat P2X4 purinoceptor: evidence for allosteric interactions of purinoceptor antagonists and monovalent cations with P2X purinoceptors. Mol Pharmacol 51:524-532.
    • (1997) Mol Pharmacol , vol.51 , pp. 524-532
    • Michel, A.D.1    Miller, K.J.2    Lundstrom, K.3    Buell, G.N.4    Humphrey, P.P.5
  • 39
    • 0030921149 scopus 로고    scopus 로고
    • Role of ATP in fast excitatory synaptic potentials in locus coeruleus neurones of the rat
    • Nieber K, Poelchen W, Illes P (1997) Role of ATP in fast excitatory synaptic potentials in locus coeruleus neurones of the rat. Br J Pharmacol 122:423-430.
    • (1997) Br J Pharmacol , vol.122 , pp. 423-430
    • Nieber, K.1    Poelchen, W.2    Illes, P.3
  • 40
    • 0030222204 scopus 로고    scopus 로고
    • Families of ion channels with two hydrophobic segments
    • North RA (1996) Families of ion channels with two hydrophobic segments. Curr Opin Cell Biol 8:474-483.
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 474-483
    • North, R.A.1
  • 41
    • 0028303241 scopus 로고
    • Differential activation of cation channels and non-selective pores by macrophage P2z purinergic receptors expressed in Xenopus oocytes
    • Nuttle LC, Dubyak GR (1994) Differential activation of cation channels and non-selective pores by macrophage P2z purinergic receptors expressed in Xenopus oocytes. J Biol Chem 269:13988-13996.
    • (1994) J Biol Chem , vol.269 , pp. 13988-13996
    • Nuttle, L.C.1    Dubyak, G.R.2
  • 42
    • 0032465105 scopus 로고    scopus 로고
    • A purinergic component of the excitatory postsynaptic current mediated by P2X receptors in the CA1 neurons of the rat hippocampus
    • Pankratov Y, Castro E, Miras-Portugal MT, Krishtal O (1998) A purinergic component of the excitatory postsynaptic current mediated by P2X receptors in the CA1 neurons of the rat hippocampus. Eur J Neurosci 10:3898-3902.
    • (1998) Eur J Neurosci , vol.10 , pp. 3898-3902
    • Pankratov, Y.1    Castro, E.2    Miras-Portugal, M.T.3    Krishtal, O.4
  • 43
    • 0344961387 scopus 로고    scopus 로고
    • Responses to ATP application on interneurons in hippocampal brain slices show prolonged desensitization
    • Proctor W, Dunwiddie T (1998) Responses to ATP application on interneurons in hippocampal brain slices show prolonged desensitization. Soc Neurosci Abstr 24:1602.
    • (1998) Soc Neurosci Abstr , vol.24 , pp. 1602
    • Proctor, W.1    Dunwiddie, T.2
  • 44
    • 85013539887 scopus 로고
    • Methods for expression of excitability proteins in Xenopus oocytes
    • (Narahashi T, ed), San Diego: Academic
    • Quick MW, Lester HA (1994) Methods for expression of excitability proteins in Xenopus oocytes. In: Ion channels of excitable cells, (Narahashi T, ed), pp 261-279. San Diego: Academic.
    • (1994) Ion Channels of Excitable Cells , pp. 261-279
    • Quick, M.W.1    Lester, H.A.2
  • 45
    • 0031754497 scopus 로고    scopus 로고
    • Receptors for purines and pyrimidines
    • Ralevic V, Burnstock G (1998) Receptors for purines and pyrimidines. Pharmacol Rev 50:413-492.
    • (1998) Pharmacol Rev , vol.50 , pp. 413-492
    • Ralevic, V.1    Burnstock, G.2
  • 46
    • 0029670647 scopus 로고    scopus 로고
    • A novel neuronal P2x ATP receptor ion channel with widespread distribution in the brain
    • Seguela P, Haghighi A, Soghomonian JJ, Cooper E (1996) A novel neuronal P2x ATP receptor ion channel with widespread distribution in the brain. J Neurosci 16:448-455.
    • (1996) J Neurosci , vol.16 , pp. 448-455
    • Seguela, P.1    Haghighi, A.2    Soghomonian, J.J.3    Cooper, E.4
  • 48
    • 0030814969 scopus 로고    scopus 로고
    • Different sensitivities to pH of ATP-induced currents at four cloned P2X receptors
    • Stoop R, Surprenant A, North RA (1997) Different sensitivities to pH of ATP-induced currents at four cloned P2X receptors. J Neurophysiol 78:1837-1840.
    • (1997) J Neurophysiol , vol.78 , pp. 1837-1840
    • Stoop, R.1    Surprenant, A.2    North, R.A.3
  • 49
    • 0028987118 scopus 로고
    • P2X receptors bring new structure to ligand-gated ion channels
    • Surprenant A, Buell G, North RA (1995) P2X receptors bring new structure to ligand-gated ion channels. Trends Neurosci 18:224-229.
    • (1995) Trends Neurosci , vol.18 , pp. 224-229
    • Surprenant, A.1    Buell, G.2    North, R.A.3
  • 50
    • 0029665112 scopus 로고    scopus 로고
    • The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)
    • Surprenant A, Rassendren F, Kawashima E, North RA, Buell G (1996) The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science 272:735-738.
    • (1996) Science , vol.272 , pp. 735-738
    • Surprenant, A.1    Rassendren, F.2    Kawashima, E.3    North, R.A.4    Buell, G.5
  • 51
    • 0032217176 scopus 로고    scopus 로고
    • Co-expression of P2X1 and P2X5 receptor subunits reveals a novel ATP-gated ion channel
    • Torres GE, Haines WR, Egan TM, Voigt MM (1998) Co-expression of P2X1 and P2X5 receptor subunits reveals a novel ATP-gated ion channel. Mol Pharmacol 54:989-993.
    • (1998) Mol Pharmacol , vol.54 , pp. 989-993
    • Torres, G.E.1    Haines, W.R.2    Egan, T.M.3    Voigt, M.M.4
  • 52
    • 0033525891 scopus 로고    scopus 로고
    • Hetero-oligomeric assembly of P2X receptor subunits. Specificities exist with regard to possible partners
    • Torres G, Egan T, Voigt M (1999) Hetero-oligomeric assembly of P2X receptor subunits. Specificities exist with regard to possible partners. J Biol Chem 274:6653-6659.
    • (1999) J Biol Chem , vol.274 , pp. 6653-6659
    • Torres, G.1    Egan, T.2    Voigt, M.3
  • 53
    • 0029801095 scopus 로고    scopus 로고
    • Treatment of onchocerciasis
    • Van Laethem Y, Lopez C (1996) Treatment of onchocerciasis. Drug 52:861-869.
    • (1996) Drug , vol.52 , pp. 861-869
    • Van Laethem, Y.1    Lopez, C.2
  • 55
    • 0031035165 scopus 로고    scopus 로고
    • Potentiation of ATP-responses at a recombinant P2x2 receptor by neurotransmitters and related substances
    • Wildman SS, King BF, Burnstock G (1997) Potentiation of ATP-responses at a recombinant P2x2 receptor by neurotransmitters and related substances. Br J Pharmacol 120:221-224.
    • (1997) Br J Pharmacol , vol.120 , pp. 221-224
    • Wildman, S.S.1    King, B.F.2    Burnstock, G.3
  • 56
    • 0031596639 scopus 로고    scopus 로고
    • 2+ modulation of ATP-responses at recombinant P2X2 receptors and its dependence on extracellular pH
    • 2+ modulation of ATP-responses at recombinant P2X2 receptors and its dependence on extracellular pH. Br J Pharmacol 123:1214-1220.
    • (1998) Br J Pharmacol , vol.123 , pp. 1214-1220
    • Wildman, S.S.1    King, B.F.2    Burnstock, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.