Contribution of transmembrane regions to ATP-gated P2X2 channel permeability dynamics

Journal of Biological Chemistry

Volumn 280, Issue 7, 2005, Pages 6118-6129

  Khakh, Baljit S ^a   Egan, Terrance M ^a,b  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; ELECTROPHYSIOLOGY; FLUORESCENCE; MATHEMATICAL MODELS; MICROSCOPIC EXAMINATION; MUTAGENESIS; PERTURBATION TECHNIQUES;

CHANNEL PERMEABILITY; FLUORESCENCE MICROSCOPY; ORGANIC CATIONS; PLASMA MEMBRANES;

ENZYMES;

ADENOSINE TRIPHOSPHATE; ALANINE; GLUTAMINE; GLYCINE; ISOLEUCINE; LEUCINE; LYSINE; PHENYLALANINE; SERINE; TRYPTOPHAN;

AMINO ACID SUBSTITUTION; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL MEMBRANE TRANSPORT; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; MEMBRANE CHANNEL; MUTATIONAL ANALYSIS; P2X 2 CHANNEL; PRIORITY JOURNAL; PROTEIN DOMAIN;

ADENOSINE TRIPHOSPHATE; ALANINE; AMINO ACID SEQUENCE; CALCIUM; CELL LINE; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; ELECTRIC CONDUCTIVITY; FLUORESCENT DYES; HUMANS; ION TRANSPORT; KINETICS; MOLECULAR SEQUENCE DATA; MOVEMENT; MUTAGENESIS; MUTATION; PROTEIN CONFORMATION; PROTEIN SUBUNITS; RECEPTORS, PURINERGIC P2;

EID: 14044274324     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M411324200     Document Type: Article

References (60)

1. Khakh, B. S. (2001) Nat. Rev. Neurosci. 2, 165-174
2. North, R. A. (2002) Physiol. Rev. 82, 1013-1067
3. Norenberg, W., and Illes, P. (2000) Naunyn-Schmiedeberg's Arch. Pharmacol. 362, 324-339
4. Pankratov, Y. V., Lalo, U. V., and Krishtal, O. A. (2002) J. Neurosci. 22, 8363-8369
5. Torres, G., Egan, T., and Voigt, M. (1999) J. Biol. Chem. 274, 6653-6659
6. Nicke, A., Baumert, H. G., Rettinger, J., Eichele, A., Lambrecht, G., Mutschler, E., and Schmalzing, G. (1998) EMBO J. 17, 3016-3028
7. Stoop, R., Thomas, S., Rassendren, F., Kawashima, E., Buell, G., Surprenant, A., and North, R. (1999) Mol. Pharmacol. 56, 973-981
8. Jiang, L. H., Kim, M., Spelta, V., Bo, X., Surprenant, A., and North, R. A. (2003) J. Neurosci. 23, 8903-8910
9. Aschrafi, A., Sadtler, S., Niculescu, C., Rettinger, J., and Schmalzing, G. (2004) J. Mol. Biol. 342, 333-343
10. Nicke, A., Rettinger, J., and Schmalzing, G. (2003) Mol. Pharmacol. 63, 243-252
11. Egan, T. M., Haines, W. R., and Voigt, M. M. (1998) J. Neurosci. 18, 2350-2359
12. Haines, W. R., Voigt, M. M., Migita, K., Torres, G. E., and Egan, T. M. (2001) J. Neurosci. 21, 5885-5892
13. Rassendren, F., Buell, G., Newbolt, A., North, R. A., and Surprenant, A. (1997) EMBO J. 16, 3446-3454
14. Jiang, L. H., Rassendren, F., Spelta, V., Surprenant, A., and North, R. A. (2001) J. Biol. Chem. 276, 14902-14908
15. Egan, T. M., and Khakh, B. S. (2004) J. Neurosci. 24, 3413-3420
16. Khakh, B. S., Bao, X., Labarca, C., and Lester, H. A. (1999) Nat. Neurosci. 2, 322-330
17. Virginio, C., MacKenzie, A., Rassendren, F. A., North, R. A., and Surprenant, A. (1999) Nat. Neurosci. 2, 315-321
18. Khakh, B. S., Smith, W. B., Chiu, C. S., Ju, D., Davidson, N., and Lester, H. A. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 5288-5293
19. Schlichter, R., Rodeau, J. L., and Hugel, S. (2002) FENS Abstr. 1, A081.017
20. Surprenant, A., Rassendren, F., Kawashima, E., North, R. A., and Buell, G. (1996) Science 272, 735-738
21. MacKenzie, A., Wilson, H. L., Kiss-Toth, E., Dower, S. K., North, R. A., and Surprenant, A. (2001) Immunity 15, 825-835
22. Khakh, B. S., and Lester, H. A. (1999) Neuron 23, 653-658
23. Smart, M. L., Panchal, R. G., Bowser, D. N., Williams, D. A., and Petrou, S. (2002) Am. J. Physiol. 283, C77-C84
24. Smart, M. L., Gu, B., Panchal, R. G., Wiley, J., Cromer, B., Williams, D. A., and Petrou, S. (2003) J. Biol. Chem. 278, 8853-8860
25. Nuttle, L. C., and Dubyak, G. R. (1994) J. Biol. Chem. 269, 13988-13996
26. Virginio, C., MacKenzie, A., North, R. A., and Surprenant, A. (1999) J. Physiol. (Lond.) 519, 335-346
27. Nakazawa, K., Fujimori, K., Takanaka, A., and Inoue, K. (1991) J. Physiol. (Lond.) 434, 647-660
28. Duan, S., Anderson, C. M., Keung, E. C., Chen, Y., Chen, Y., and Swanson, R. A. (2003) J. Neurosci. 23, 1320-1328
29. Hille, B. (2001) Ion Channels of Excitable Membranes, Sinauer Associates Inc., Sunderland, MA
30. Cockcroft, S., and Gomperts, B. D. (1979) Nature 279, 541-542
31. Fujiwara, Y., and Kubo, Y. (2004) J. Physiol. 558, 31-43
32. Spencer, R. H., and Rees, D. C. (2002) Annu. Rev. Biophys. Biomol. Struct. 31, 207-233
33. Eickhorst, A., Berson, A., Cockayne, D., Lester, H. A., and Khakh, B. S. (2002) J. Gen. Physiol. 120, 119-131
34. Fisher, J. A., Girdler, G., and Khakh, B. S. (2004) J. Neurosci. 24, 10475-10487
35. Doyle, D. A. (2004) Trends Neurosci. 27, 298-302
36. Steyer, J. A., and Almers, W. (2001) Nat. Rev. Mol. Cell. Biol. 2, 268-275
37. Riven, I., Kalmanzon, E., Segev, L., and Reuveny, E. (2003) Neuron 38, 225-235
38. Leite, J. F., Blanton, M. P., Shahgholi, M., Dougherty, D. A., and Lester, H. A. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 13054-13059
39. Haines, W. R., Migita, K., Cox, J. A., Egan, T. M., and Voigt, M. M. (2001) J. Biol. Chem. 276, 32793-32798
40. Li, Z., Migita, K., Samways, D. S., Voigt, M. M., and Egan, T. M. (2004) J. Neurosci. 24, 9378-9386
41. Dwyer, T. M., Adams, D. J., and Hille, B. (1980) J. Gen. Physiol. 75, 469-492
42. Migita, K., Haines, W. R., Voigt, M. M., and Egan, T. M. (2001) J. Biol. Chem. 276, 30934-30941
43. Brake, A. J., Wagenbach, M. J., and Julius, D. (1994) Nature 371, 519-523
44. Dahan, D. S., Dibas, M. I., Petersson, E. J., Auyeung, V. C., Chanda, B., Bezanilla, F., Dougherty, D. A., and Lester, H. A. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 10195-10200
45. Eskandari, S., Kreman, M., Kavanaugh, M. P., Wright, E. M., and Zampighi, G. A. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 8641-8646
46. Chaumont, S., Jiang, L. H., Penna, A., North, R. A., and Rassendren, F. (2004) J. Biol. Chem. 279, 29628-29638
47. Kobrinsky, E., Mirshahi, T., Zhang, H., Jin, T., and Logothetis, D. E. (2000) Nat. Cell Biol. 2, 507-514
48. Hirose, K., Kadowaki, S., Tanabe, M., Takeshima, H., and Iino, M. (1999) Science 284, 1527-1530
49. Kortemme, T., Kim, D. E., and Baker, D. (2004) Science's STKE 219, 12
50. Yifrach, O., and MacKinnon, R. (2002) Cell 111, 231-239
51. Hackos, D. H., Chang, T. H., and Swartz, K. J. (2002) J. Gen. Physiol. 119, 521-532
52. Li-Smerin, Y., and Swartz, K. J. (2001) J. Gen. Physiol. 117, 205-218
53. Collins, A., Chuang, H., Jan, Y. N., and Jan, J. Y. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 5456-5460
54. Roberts, J. A., and Evans, R. J. (2004) J. Biol. Chem. 279, 9043-9055
55. Spelta, V., Jiang, L. H., Bailey, R. J., Surprenant, A., and North, R. A. (2003) Br. J. Pharmacol. 138, 131-136
56. Khakh, B. S., Proctor, W. R., Dunwiddie, T. V., Labarca, C., and Lester, H. A. (1999) J. Neurosci 19, 7289-7299
57. Tsien, R. Y. (1998) Annu. Rev. Biochem. 67, 509-544
58. Bobanovic, L. K., Royle, S. J., and Murrell-Lagnado, R. D. (2002) J. Neurosci. 22, 4814-4824
59. Perozo, E., Cortes, D. M., Sompornpisut, P., Kloda, A., and Martinac, B. (2002) Nature 418, 942-948
60. Sukharev, S., Betanzos, M., Chiang, C. S., and Guy, H. R. (2001) Nature 409, 720-724