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Volumn 4, Issue 5, 2013, Pages 477-494

The CCN family acting throughout the body: Recent research developments

Author keywords

CCN family; Fibrosis; Gene regulation; Malignancy; Matricellular protein

Indexed keywords

CCN PROTEIN;

EID: 84888625806     PISSN: 18685021     EISSN: 1868503X     Source Type: Journal    
DOI: 10.1515/bmc-2013-0018     Document Type: Article
Times cited : (59)

References (142)
  • 3
    • 33845906843 scopus 로고    scopus 로고
    • All in the ccn family: Essential matricellular signaling modulators emerge from the bunker
    • Leask A, Abraham DJ. All in the CCN family: essential matricellular signaling modulators emerge from the bunker. J Cell Sci 2006; 119: 4803-10.
    • (2006) J Cell Sci , vol.119 , pp. 4803-4810
    • Leask, A.1    Abraham, D.J.2
  • 4
    • 33847627603 scopus 로고    scopus 로고
    • Ccn family proteins and angiogenesis: From embryo to adulthood
    • Kubota S, Takigawa M. CCN family proteins and angiogenesis: from embryo to adulthood. Angiogenesis 2007; 10: 1-11.
    • (2007) Angiogenesis , vol.10 , pp. 1-11
    • Kubota, S.1    Takigawa, M.2
  • 5
    • 82455198983 scopus 로고    scopus 로고
    • Taking aim at the extracellular matrix: Ccn proteins as emerging therapeutic targets
    • Jun JI, Lau LF. Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets. Nat Rev Drug Discov 2011; 10: 9459-63.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 9459-9463
    • Jun, J.I.1    Lau, L.F.2
  • 7
    • 0037183997 scopus 로고    scopus 로고
    • Matrix metalloproteinases cleave connective tissue growth factor and reactivate angiogenic activity of vascular endothelial growth factor 165
    • Hashimoto G, Inoki I, Fujii Y, Aoki T, Ikeda E, Okada Y. Matrix metalloproteinases cleave connective tissue growth factor and reactivate angiogenic activity of vascular endothelial growth factor 165. J Biol Chem 2002; 277: 36288-95.
    • (2002) J Biol Chem , vol.277 , pp. 36288-362895
    • Hashimoto, G.1    Inoki, I.2    Fujii, Y.3    Aoki, T.4    Ikeda, E.5    Okada, Y.6
  • 9
    • 33947219834 scopus 로고    scopus 로고
    • Expression and physiological role of ccn4/wnt-induced secreted protein 1 mrna splicing variants in chondrocytes
    • Yanagita T, Kubota S, Kawaki H, Kawata K, Kondo S, Takano-Yamamoto T, Tanaka S, Takigawa M. Expression and physiological role of CCN4/Wnt-induced secreted protein 1 mRNA splicing variants in chondrocytes. FEBS J 2007; 274: 1655-65.
    • (2007) FEBS J , vol.274 , pp. 1655-1665
    • Yanagita, T.1    Kubota, S.2    Kawaki, H.3    Kawata, K.4    Kondo, S.5    Takano-Yamamoto, T.6    Tanaka, S.7    Takigawa, M.8
  • 10
    • 84857791001 scopus 로고    scopus 로고
    • Adhesion-modulating/matricellular ecm protein families: A structural, functional and evolutionary appraisal
    • Mosher DF, Adams JC. Adhesion-modulating/matricellular ECM protein families: a structural, functional and evolutionary appraisal. Matrix Biol 2012; 31: 155-61.
    • (2012) Matrix Biol , vol.31 , pp. 155-1561
    • Mosher, D.F.1    Adams, J.C.2
  • 11
    • 79959351079 scopus 로고    scopus 로고
    • First structural glimpse of ccn3 and ccn5 multifunctional signaling regulators elucidated by small angle x-ray scattering
    • Holbourn KP, Malfois M, Acharya KR. First structural glimpse of CCN3 and CCN5 multifunctional signaling regulators elucidated by small angle x-ray scattering. J Biol Chem 2011; 286: 22243-9.
    • (2011) J Biol Chem , vol.286 , pp. 22243-22249
    • Holbourn, K.P.1    Malfois, M.2    Acharya, K.R.3
  • 12
    • 84866344934 scopus 로고    scopus 로고
    • Roles of heterotypic ccn2/ctgf-ccn3/nov and homotypic ccn2-ccn2 interactions in expression of the differentiated phenotype of chondrocytes
    • Hoshijima M, Hattori T, Aoyama E, Nishida T, Yamashiro T, Takigawa M. Roles of heterotypic CCN2/CTGF-CCN3/NOV and homotypic CCN2-CCN2 interactions in expression of the differentiated phenotype of chondrocytes. FEBS J 2012; 279: 3584-97.
    • (2012) FEBS J , vol.279 , pp. 3584-3597
    • Hoshijima, M.1    Hattori, T.2    Aoyama, E.3    Nishida, T.4    Yamashiro, T.5    Takigawa, M.6
  • 13
    • 84862095866 scopus 로고    scopus 로고
    • Cyr61 induces il-6 production by fibroblast-like synoviocytes promoting th17 differentiation in rheumatoid arthritis
    • Lin J, Zhou Z, Huo R, Xiao L, Ouyang G, Wang L, Sun Y, Shen B, Li D, Li N. Cyr61 induces IL-6 production by fibroblast-like synoviocytes promoting Th17 differentiation in rheumatoid arthritis. J Immunol 2012; 188: 5776-84.
    • (2012) J Immunol , vol.188 , pp. 5776-5784
    • Lin, J.1    Zhou, Z.2    Huo, R.3    Xiao, L.4    Ouyang, G.5    Wang, L.6    Sun, Y.7    Shen, B.8    Li, D.9    Li, N.10
  • 14
    • 1542305557 scopus 로고    scopus 로고
    • Connective tissue growth factor (ccn2) induces adhesion of rat activated hepatic stellate cells by binding of its c-Terminal domain to integrin 〈(v)®(3) and heparan sulfate proteoglycan
    • Gao R, Brigstock DR. Connective tissue growth factor (CCN2) induces adhesion of rat activated hepatic stellate cells by binding of its C-Terminal domain to integrin 〈(v)®(3) and heparan sulfate proteoglycan. J Biol Chem 2004; 279: 8848-55.
    • (2004) J Biol Chem , vol.279 , pp. 8848-8855
    • Gao, R.1    Brigstock, D.R.2
  • 15
    • 84857154364 scopus 로고    scopus 로고
    • Tnf〈-induced apoptosis enabled by ccn1/cyr61: Pathways of reactive oxygen species generation and cytochrome c release
    • Juric V, Chen CC, Lau LF. TNF〈-induced apoptosis enabled by CCN1/CYR61: pathways of reactive oxygen species generation and cytochrome c release. PLoS One 2012; 7: e31303.
    • (2012) PLoS One , vol.7
    • Juric, V.1    Chen, C.C.2    Lau, L.F.3
  • 16
    • 77949674681 scopus 로고    scopus 로고
    • Cyr61/ ccn1 displays high-Affinity binding to the somatomedin b(1-44) domain of vitronectin
    • Francischetti IM, Kotsyfakis M, Andersen JF, Lukszo J. Cyr61/ CCN1 displays high-Affinity binding to the somatomedin B(1-44) domain of vitronectin. PLoS One 2010; 5: e9356.
    • (2010) PLoS One , vol.5
    • Francischetti, I.M.1    Kotsyfakis, M.2    Andersen, J.F.3    Lukszo, J.4
  • 18
    • 84870834470 scopus 로고    scopus 로고
    • Ctgf increases il-6 expression in human synovial fibroblasts through integrin-dependent signaling pathway
    • Liu SC, Hsu CJ, Chen HT, Tsou HK, Chuang SM, Tang CH. CTGF increases IL-6 expression in human synovial fibroblasts through integrin-dependent signaling pathway. PLoS One 2012; 7: e51097.
    • (2012) PLoS One , vol.7
    • Liu, S.C.1    Hsu, C.J.2    Chen, H.T.3    Tsou, H.K.4    Chuang, S.M.5    Tang, C.H.6
  • 21
    • 80055016472 scopus 로고    scopus 로고
    • The role of ccn2 in cartilage and bone development
    • Kubota S, Takigawa M. The role of CCN2 in cartilage and bone development. J Cell Commun Signal 2011; 5: 209-17.
    • (2011) J Cell Commun Signal , vol.5 , pp. 209-517
    • Kubota, S.1    Takigawa, M.2
  • 22
    • 84880324961 scopus 로고    scopus 로고
    • A novel role of ccn2 in rank/rankl/opg signaling
    • Aoyama E, Kubota S, Nishida T, Takigawa M. A novel role of CCN2 in RANK/RANKL/OPG signaling. J Dent Res 2013; 92: Special issue A: 1329.
    • (2013) J Dent Res , vol.92 , Issue.A , pp. 1329
    • Aoyama, E.1    Kubota, S.2    Nishida, T.3    Takigawa, M.4
  • 26
    • 84870491182 scopus 로고    scopus 로고
    • Ccn2/ctgf binds to fibroblast growth factor receptor 2 and modulates its signaling
    • Aoyama E, Kubota S, Takigawa M. CCN2/CTGF binds to fibroblast growth factor receptor 2 and modulates its signaling. FEBS Lett 2012; 586: 4270-5.
    • (2012) FEBS Lett , vol.586 , pp. 4270-4275
    • Aoyama, E.1    Kubota, S.2    Takigawa, M.3
  • 27
    • 59449095447 scopus 로고    scopus 로고
    • Ccn family 2/connective tissue growth factor modulates bmp signalling as a signal conductor, which action regulates the proliferation and differentiation of chondrocytes
    • Maeda A, Nishida T, Aoyama E, Kubota S, Lyons KM, Kuboki T, Takigawa M. CCN family 2/connective tissue growth factor modulates BMP signalling as a signal conductor, which action regulates the proliferation and differentiation of chondrocytes. J Biochem 2009; 145: 207-16.
    • (2009) J Biochem , vol.145 , pp. 207-216
    • Maeda, A.1    Nishida, T.2    Aoyama, E.3    Kubota, S.4    Lyons, K.M.5    Kuboki, T.6    Takigawa, M.7
  • 28
    • 80054894825 scopus 로고    scopus 로고
    • Effect of ccn2 on fgf2-induced proliferation and mmp9 and mmp13 productions by chondrocytes
    • Nishida T, Kubota S, Aoyama E, Janune D, Maeda A, Takigawa M. Effect of CCN2 on FGF2-induced proliferation and MMP9 and MMP13 productions by chondrocytes. Endocrinology 2011; 182: 4232-41.
    • (2011) Endocrinology , vol.182 , pp. 4232-4241
    • Nishida, T.1    Kubota, S.2    Aoyama, E.3    Janune, D.4    Maeda, A.5    Takigawa, M.6
  • 29
    • 84864754659 scopus 로고    scopus 로고
    • Ccn2/ctgf regulates neovessel formation via targeting structurally conserved cystine knot motifs in multiple angiogenic regulators
    • Pi L, Shenoy AK, Liu J, Kim S, Nelson N, Xia H, Hauswirth WW, Petersen BE, Schultz GS, Scott EW. CCN2/CTGF regulates neovessel formation via targeting structurally conserved cystine knot motifs in multiple angiogenic regulators. FASEB J 2012; 26: 3365-79.
    • (2012) FASEB J , vol.26 , pp. 3365-3379
    • Pi, L.1    Shenoy, A.K.2    Liu, J.3    Kim, S.4    Nelson, N.5    Xia, H.6    Hauswirth, W.W.7    Petersen, B.E.8    Schultz, G.S.9    Scott, E.W.10
  • 31
    • 84872593277 scopus 로고    scopus 로고
    • Ccn4 induces il-6 production through 〈v®5 receptor, pi3k, akt, and nf-|b singling pathway in human synovial fibroblasts
    • Hou CH, Tang CH, Hsu CJ, Hou SM, Liu JF. CCN4 induces IL-6 production through 〈v®5 receptor, PI3K, Akt, and NF-|B singling pathway in human synovial fibroblasts. Arthritis Res Ther 2013; 15: R19.
    • (2013) Arthritis Res Ther , vol.15
    • Hou, C.H.1    Tang, C.H.2    Hsu, C.J.3    Hou, S.M.4    Liu, J.F.5
  • 32
    • 79961126182 scopus 로고    scopus 로고
    • Wisp2/ccn5 up-regulated in the central nervous system of gm3-only mice facilitates neurite formation in neuro2a cells via integrin-Akt signaling
    • Ohkawa Y, Ohmi Y, Tajima O, Yamauchi Y, Furukawa K, Furukawa K. Wisp2/CCN5 up-regulated in the central nervous system of GM3-only mice facilitates neurite formation in Neuro2a cells via integrin-Akt signaling. Biochem Biophys Res Commun 2011; 411: 483-9.
    • (2011) Biochem Biophys Res Commun , vol.411 , pp. 483-489
    • Ohkawa, Y.1    Ohmi, Y.2    Tajima, O.3    Yamauchi, Y.4    Furukawa, K.5    Furukawa, K.6
  • 34
    • 78650936271 scopus 로고    scopus 로고
    • Wisp-1/ccn4 regulates osteogenesis by enhancing bmp-2 activity
    • Ono M, Inkson CA, Kilts TM, Young MF. WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity. J Bone Miner Res 2011; 26: 193-208.
    • (2011) J Bone Miner Res , vol.26 , pp. 193-208
    • Ono, M.1    Inkson, C.A.2    Kilts, T.M.3    Young, M.F.4
  • 35
    • 84866356504 scopus 로고    scopus 로고
    • Ccn6 modulates bmp signaling via the smad-independent tak1/p38 pathway, acting to suppress metastasis of breast cancer
    • Pal A, Huang W, Li X, Toy KA, Nikolovska-Coleska Z, Kleer CG. CCN6 modulates BMP signaling via the Smad-independent TAK1/p38 pathway, acting to suppress metastasis of breast cancer. Cancer Res 2012; 72: 4818-28.
    • (2012) Cancer Res , vol.72 , pp. 4818-4828
    • Pal, A.1    Huang, W.2    Li, X.3    Toy, K.A.4    Nikolovska-Coleska, Z.5    Kleer, C.G.6
  • 36
    • 34948831652 scopus 로고    scopus 로고
    • The ccn family member wisp3, mutant in progressive pseudorheumatoid dysplasia, modulates bmp and wnt signaling
    • Nakamura Y, Weidinger G, Liang JO, Aquilina-Beck A, Tamai K, Moon RT, Warman ML. The CCN family member Wisp3, mutant in progressive pseudorheumatoid dysplasia, modulates BMP and Wnt signaling. J Clin Invest 2007; 117: 3075-86.
    • (2007) J Clin Invest , vol.117 , pp. 3075-3086
    • Nakamura, Y.1    Weidinger, G.2    Liang, J.O.3    Aquilina-Beck, A.4    Tamai, K.5    Moon, R.T.6    Warman, M.L.7
  • 37
    • 84877992436 scopus 로고    scopus 로고
    • Wisp3-igf1 interaction regulates chondrocyte hypertrophy
    • Repudi SR, Patra M, Sen M. WISP3-IGF1 interaction regulates chondrocyte hypertrophy. J Cell Sci 2013; 126: 1650-8.
    • (2013) J Cell Sci , vol.126 , pp. 1650-1658
    • Repudi, S.R.1    Patra, M.2    Sen, M.3
  • 40
    • 33750169244 scopus 로고    scopus 로고
    • Comparable response of ccn1 with ccn2 genes upon arthritis: An in vitro evaluation with a human chondrocytic cell line stimulated by a set of cytokines
    • Moritani NH, Kubota S, Sugahara T, Takigawa M. Comparable response of ccn1 with ccn2 genes upon arthritis: an in vitro evaluation with a human chondrocytic cell line stimulated by a set of cytokines. Cell Commun Signal 2005; 3: 6.
    • (2005) Cell Commun Signal , vol.3 , pp. 6
    • Moritani, N.H.1    Kubota, S.2    Sugahara, T.3    Takigawa, M.4
  • 41
    • 84866386719 scopus 로고    scopus 로고
    • Glucocorticoids induce ccn5/wisp-2 expression and attenuate invasion in oestrogen receptor-negative human breast cancer cells
    • Ferrand N, Stragier E, Redeuilh G, Sabbah M. Glucocorticoids induce CCN5/WISP-2 expression and attenuate invasion in oestrogen receptor-negative human breast cancer cells. Biochem J 2012; 447: 71-9.
    • (2012) Biochem J , vol.447 , pp. 71-79
    • Ferrand, N.1    Stragier, E.2    Redeuilh, G.3    Sabbah, M.4
  • 42
    • 33644643752 scopus 로고    scopus 로고
    • Dexamethasone induces connective tissue growth factor expression in renal tubular epithelial cells in a mouse strain-specific manner
    • Okada H, Kikuta T, Inoue T, Kanno Y, Ban S, Sugaya T, Takigawa M, Suzuki H. Dexamethasone induces connective tissue growth factor expression in renal tubular epithelial cells in a mouse strain-specific manner. Am J Pathol 2006; 168: 737-47.
    • (2006) Am J Pathol , vol.168 , pp. 737-747
    • Okada, H.1    Kikuta, T.2    Inoue, T.3    Kanno, Y.4    Ban, S.5    Sugaya, T.6    Takigawa, M.7    Suzuki, H.8
  • 43
    • 33644913383 scopus 로고    scopus 로고
    • Contrasting role of phospholipase c-©1 in the expression of immediate early genes induced by epidermal or platelet-derived growth factors
    • Liao HJ, de Los Santos J, Carpenter G. Contrasting role of phospholipase C-©1 in the expression of immediate early genes induced by epidermal or platelet-derived growth factors. Exp Cell Res 2006; 312: 807-16.
    • (2006) Exp Cell Res , vol.312 , pp. 807-816
    • Liao, H.J.1    De Los Santos, J.2    Carpenter, G.3
  • 44
    • 80055009055 scopus 로고    scopus 로고
    • Substance p induces ccn1 expression via histone deacetylase activity in human colonic epithelial cells
    • Koon HW, Shih DQ, Hing TC, Chen J, Ho S, Zhao D, Targan SR, Pothoulakis C. Substance P induces CCN1 expression via histone deacetylase activity in human colonic epithelial cells. Am J Pathol 2011; 179: 2315-26.
    • (2011) Am J Pathol , vol.179 , pp. 2315-2326
    • Koon, H.W.1    Shih, D.Q.2    Hing, T.C.3    Chen, J.4    Ho, S.5    Zhao, D.6    Targan, S.R.7    Pothoulakis, C.8
  • 45
    • 79956024624 scopus 로고    scopus 로고
    • Ccn1, a candidate target for zoledronic acid treatment in breast cancer
    • Espinoza I, Liu H, Busby R, Lupu R. CCN1, a candidate target for zoledronic acid treatment in breast cancer. Mol Cancer Ther 2011; 10: 732-41.
    • (2011) Mol Cancer Ther , vol.10 , pp. 732-741
    • Espinoza, I.1    Liu, H.2    Busby, R.3    Lupu, R.4
  • 46
    • 81455141243 scopus 로고    scopus 로고
    • Cigarette smokeinduced early growth response-1 regulates the expression of the cysteine-rich 61 in human skin dermal fibroblasts
    • Kim JN, Kim HJ, Jeong SH, Kye YC, Son SW. Cigarette smokeinduced early growth response-1 regulates the expression of the cysteine-rich 61 in human skin dermal fibroblasts. Exp Dermatol 2011; 20: 992-7.
    • (2011) Exp Dermatol , vol.20 , pp. 992-997
    • Kim, J.N.1    Kim, H.J.2    Jeong, S.H.3    Kye, Y.C.4    Son, S.W.5
  • 47
    • 84864320125 scopus 로고    scopus 로고
    • Angiotensin ii increases ctgf expression via mapks/tgf-®1/ traf6 pathway in atrial fibroblasts
    • Gu J, Liu X, Wang QX, Tan HW, Guo M, Jiang WF, Zhou L. Angiotensin II increases CTGF expression via MAPKs/TGF-®1/ TRAF6 pathway in atrial fibroblasts. Exp Cell Res 2012; 318: 2105-15.
    • (2012) Exp Cell Res , vol.318 , pp. 2105-215
    • Gu, J.1    Liu, X.2    Wang, Q.X.3    Tan, H.W.4    Guo, M.5    Jiang, W.F.6    Zhou, L.7
  • 49
    • 84861176253 scopus 로고    scopus 로고
    • Antiproliferative factor regulates connective tissue growth factor (ctgf/ccn2) expression in t24 bladder carcinoma cells
    • Matika CA, Wasilewski M, Arnott JA, Planey SL. Antiproliferative factor regulates connective tissue growth factor (CTGF/CCN2) expression in T24 bladder carcinoma cells. Mol Biol Cell 2012; 23: 1976-85.
    • (2012) Mol Biol Cell , vol.23 , pp. 1976-1985
    • Matika, C.A.1    Wasilewski, M.2    Arnott, J.A.3    Planey, S.L.4
  • 52
    • 84871085082 scopus 로고    scopus 로고
    • Curcumin inhibits thrombin-stimulated connective tissue growth factor (ctgf/ccn2) production through c-jun nh2-Terminal kinase suppression in human gingival fibroblasts
    • Chen YW, Yang WH, Wong MY, Chang HH, Yen-Ping Kuo M. Curcumin inhibits thrombin-stimulated connective tissue growth factor (CTGF/CCN2) production through c-Jun NH2-Terminal kinase suppression in human gingival fibroblasts. J Periodontol 2012; 83: 1546-53.
    • (2012) J Periodontol , vol.83 , pp. 1546-1553
    • Chen, Y.W.1    Yang, W.H.2    Wong, M.Y.3    Chang, H.H.4    Yen-Ping Kuo, M.5
  • 53
  • 55
    • 84055222551 scopus 로고    scopus 로고
    • Ccn2 promotes cigarette smoke-induced proliferation of rat pulmonary artery smooth muscle cells through upregulating cyclin d1 expression
    • Wang R, Xu YJ, Liu XS, Zeng DX, Xiang M. CCN2 promotes cigarette smoke-induced proliferation of rat pulmonary artery smooth muscle cells through upregulating cyclin D1 expression. J Cell Biochem 2012; 113: 349-59.
    • (2012) J Cell Biochem , vol.113 , pp. 349-359
    • Wang, R.1    Xu, Y.J.2    Liu, X.S.3    Zeng, D.X.4    Xiang, M.5
  • 57
    • 84857539208 scopus 로고    scopus 로고
    • Mmp-3 provokes ctgf/ccn2 production independently of protease activity and dependently on dynamin-related endocytosis, which contributes to human dental pulp cell migration
    • Muromachi K, Kamio N, Narita T, Annen-Kamio M, Sugiya H, Matsushima K. MMP-3 provokes CTGF/CCN2 production independently of protease activity and dependently on dynamin-related endocytosis, which contributes to human dental pulp cell migration. J Cell Biochem 2012; 113: 1348-58.
    • (2012) J Cell Biochem , vol.113 , pp. 1348-1358
    • Muromachi, K.1    Kamio, N.2    Narita, T.3    Annen-Kamio, M.4    Sugiya, H.5    Matsushima, K.6
  • 58
    • 77958481136 scopus 로고    scopus 로고
    • The gene encoding the hematopoietic stem cell regulator ccn3/nov is under direct cytokine control through the transcription factors stat5a/b
    • Kimura A, Martin C, Robinson GW, Simone JM, Chen W, Wickre MC, O'Shea JJ, Hennighausen L. The gene encoding the hematopoietic stem cell regulator CCN3/NOV is under direct cytokine control through the transcription factors STAT5A/B. J Biol Chem 2010; 285: 32704-9.
    • (2010) J Biol Chem , vol.285 , pp. 32704-32709
    • Kimura, A.1    Martin, C.2    Robinson, G.W.3    Simone, J.M.4    Chen, W.5    Wickre, M.C.6    O'Shea, J.J.7    Hennighausen, L.8
  • 59
    • 84862001701 scopus 로고    scopus 로고
    • Inhibition of fibroblast growth by notch1 signaling is mediated by induction of wnt11-dependent wisp-1
    • Liu ZJ, Li Y, Tan Y, Xiao M, Zhang J, Radtke F, Velazquez OC. Inhibition of fibroblast growth by Notch1 signaling is mediated by induction of Wnt11-dependent WISP-1. PLoS One 2012; 7: e38811.
    • (2012) PLoS One , vol.7
    • Liu, Z.J.1    Li, Y.2    Tan, Y.3    Xiao, M.4    Zhang, J.5    Radtke, F.6    Velazquez, O.C.7
  • 60
    • 64149116677 scopus 로고    scopus 로고
    • Nitric oxide increases wnt-induced secreted protein-1 (wisp-1/ccn4) expression and function in colitis
    • Wang H, Zhang R, Wen S, McCafferty DM, Beck PL, MacNaughton WK. Nitric oxide increases Wnt-induced secreted protein-1 (WISP-1/CCN4) expression and function in colitis. J Mol Med (Berl) 2009; 87: 435-45.
    • (2009) J Mol Med (Berl , vol.87 , pp. 435-445
    • Wang, H.1    Zhang, R.2    Wen, S.3    McCafferty, D.M.4    Beck, P.L.5    MacNaughton, W.K.6
  • 61
    • 84865702908 scopus 로고    scopus 로고
    • The food contaminant and nephrotoxin ochratoxin a enhances wnt1 inducible signaling protein 1 and tumor necrosis factor-〈 expression in human primary proximal tubule cells
    • Hennemeier I, Humpf HU, Gekle M, Schwerdt G. The food contaminant and nephrotoxin ochratoxin A enhances Wnt1 inducible signaling protein 1 and tumor necrosis factor-〈 expression in human primary proximal tubule cells. Mol Nutr Food Res 2012; 56: 1375-84.
    • (2012) Mol Nutr Food Res , vol.56 , pp. 1375-1384
    • Hennemeier, I.1    Humpf, H.U.2    Gekle, M.3    Schwerdt, G.4
  • 62
    • 33847712503 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 (igf-1) induces wisp-2/ccn5 via multiple molecular cross-Talks and is essential for mitogenic switch by igf-1 axis in estrogen receptor-positive breast tumor cells
    • Dhar K, Banerjee S, Dhar G, Sengupta K, Banerjee SK. Insulin-like growth factor-1 (IGF-1) induces WISP-2/CCN5 via multiple molecular cross-Talks and is essential for mitogenic switch by IGF-1 axis in estrogen receptor-positive breast tumor cells. Cancer Res 2007; 67: 1520-6.
    • (2007) Cancer Res , vol.67 , pp. 1520-1526
    • Dhar, K.1    Banerjee, S.2    Dhar, G.3    Sengupta, K.4    Banerjee, S.K.5
  • 63
    • 33746751471 scopus 로고    scopus 로고
    • Mechanical regulation of the cyr61/ccn1 and ctgf/ccn2 proteins
    • Chaqour B, Goppelt-Struebe M. Mechanical regulation of the Cyr61/CCN1 and CTGF/CCN2 proteins. FEBS J 2006; 273: 3639-49.
    • (2006) FEBS J , vol.273 , pp. 3639-3649
    • Chaqour, B.1    Goppelt-Struebe, M.2
  • 66
    • 84859977089 scopus 로고    scopus 로고
    • Ets-1 is essential for connective tissue growth factor (ctgf/ ccn2) induction by tgf-®1 in osteoblasts
    • Geisinger MT, Astaiza R, Butler T, Popoff SN, Planey SL, Arnott JA. Ets-1 is essential for connective tissue growth factor (CTGF/ CCN2) induction by TGF-®1 in osteoblasts. PLoS One 2012; 7: e35258.
    • (2012) PLoS One , vol.7
    • Geisinger, M.T.1    Astaiza, R.2    Butler, T.3    Popoff, S.N.4    Planey, S.L.5    Arnott, J.A.6
  • 68
    • 77951162370 scopus 로고    scopus 로고
    • Foxo proteins mediate hypoxic induction of connective tissue growth factor in endothelial cells
    • Samarin J, Wessel J, Cicha I, Kroening S, Warnecke C, Goppelt-Struebe M. FoxO proteins mediate hypoxic induction of connective tissue growth factor in endothelial cells. J Biol Chem 2010; 285: 4328-36.
    • (2010) J Biol Chem , vol.285 , pp. 4328-4336
    • Samarin, J.1    Wessel, J.2    Cicha, I.3    Kroening, S.4    Warnecke, C.5    Goppelt-Struebe, M.6
  • 69
    • 79953310106 scopus 로고    scopus 로고
    • Taxol resistance in breast cancer cells is mediated by the hippo pathway component taz and its downstream transcriptional targets cyr61 and ctgf
    • Lai D, Ho KC, Hao Y, Yang X. Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF. Cancer Res 2011; 71: 2728-38.
    • (2011) Cancer Res , vol.71 , pp. 2728-2738
    • Lai, D.1    Ho, K.C.2    Hao, Y.3    Yang, X.4
  • 70
    • 49649116469 scopus 로고    scopus 로고
    • Gain of oncogenic function of p53 mutants induces invasive phenotypes in human breast cancer cells by silencing ccn5/wisp-2
    • Dhar G, Banerjee S, Dhar K, Tawfik O, Mayo MS, Vanveldhuizen PJ, Banerjee SK. Gain of oncogenic function of p53 mutants induces invasive phenotypes in human breast cancer cells by silencing CCN5/WISP-2. Cancer Res 2008; 68: 4580-7.
    • (2008) Cancer Res , vol.68 , pp. 4580-4587
    • Dhar, G.1    Banerjee, S.2    Dhar, K.3    Tawfik, O.4    Mayo, M.S.5    Vanveldhuizen, P.J.6    Banerjee, S.K.7
  • 71
    • 80051791754 scopus 로고    scopus 로고
    • Nephroblastoma overexpressed (nov/ccn3) gene: A paired-domain-specific pax3-fkhr transcription target that promotes survival and motility in alveolar rhabdomyosarcoma cells
    • Zhang Y, Wang C. Nephroblastoma overexpressed (NOV/CCN3) gene: a paired-domain-specific PAX3-FKHR transcription target that promotes survival and motility in alveolar rhabdomyosarcoma cells. Oncogene 2011; 30: 3549-62.
    • (2011) Oncogene , vol.30 , pp. 3549-3562
    • Zhang, Y.1    Wang, C.2
  • 72
    • 0034726967 scopus 로고    scopus 로고
    • Identification of an rna element that confers post-Transcriptional repression of connective tissue growth factor/hypertrophic chondrocyte specific 24 (ctgf/hcs24) gene: Similarities to retroviral rna-protein interactions
    • Kubota S, Kondo S, Eguchi T, Hattori T, Nakanishi T, Pomerantz RJ, Takigawa M. Identification of an RNA element that confers post-Transcriptional repression of connective tissue growth factor/hypertrophic chondrocyte specific 24 (ctgf/hcs24) gene: similarities to retroviral RNA-protein interactions. Oncogene 2000; 19: 4773-86.
    • (2000) Oncogene , vol.19 , pp. 4773-4786
    • Kubota, S.1    Kondo, S.2    Eguchi, T.3    Hattori, T.4    Nakanishi, T.5    Pomerantz, R.J.6    Takigawa, M.7
  • 82
    • 33846626061 scopus 로고    scopus 로고
    • Role of ccn2/ctgf/hcs24 in bone growth
    • Kubota S, Takigawa M. Role of CCN2/CTGF/Hcs24 in bone growth. Int Rev Cytol 2007; 257: 1-41.
    • (2007) Int Rev Cytol , vol.257 , pp. 1-41
    • Kubota, S.1    Takigawa, M.2
  • 83
    • 84880334077 scopus 로고    scopus 로고
    • Ccn2: A master regulator of the genesis of bone and cartilage
    • Takigawa M. CCN2: A master regulator of the genesis of bone and cartilage. J Cell Commun Signal 2013; 7: 191 -201.
    • (2013) J Cell Commun Signal , vol.7 , pp. 191-201
    • Takigawa, M.1
  • 92
    • 43149111611 scopus 로고    scopus 로고
    • Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the nov (ccn3) gene
    • Heath E, Tahri D, Andermarcher E, Schofield P, Fleming S, Boulter CA. Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) gene. Dev Biol 2008; 8: 18.
    • (2008) Dev Biol , vol.8 , pp. 18
    • Heath, E.1    Tahri, D.2    Andermarcher, E.3    Schofield, P.4    Fleming, S.5    Boulter, C.A.6
  • 93
  • 94
    • 84855825971 scopus 로고    scopus 로고
    • Molecular differentiation between osteophytic and articular cartilage-clues for a transient and permanent chondrocyte phenotype
    • Gelse K, Ekici AB, Cipa F, Swoboda B, Carl HD, Olk A, Hennig FF, Klinger P. Molecular differentiation between osteophytic and articular cartilage -clues for a transient and permanent chondrocyte phenotype. Osteoarthritis Cartilage 2012; 20: 162-71.
    • (2012) Osteoarthritis Cartilage , vol.20 , pp. 162-171
    • Gelse, K.1    Ekici, A.B.2    Cipa, F.3    Swoboda, B.4    Carl, H.D.5    Olk, A.6    Hennig, F.F.7    Klinger, P.8
  • 96
    • 33750480252 scopus 로고    scopus 로고
    • The matricellular protein ccn1 is essential for cardiac development
    • Mo FE, Lau LF. The matricellular protein CCN1 is essential for cardiac development. Circ Res 2006; 99: 961-9.
    • (2006) Circ Res , vol.99 , pp. 961-969
    • Mo, F.E.1    Lau, L.F.2
  • 98
    • 33244456090 scopus 로고    scopus 로고
    • Hypoxic regulation of stability of connective tissue growth factor/ccn2 mrna by 3′-untranslated region interacting with a cellular protein in human chondrosarcoma cells
    • Kondo S, Kubota S, Mukudai Y, Moritani N, Nishida T, Matsushita H, Matsumoto S, Sugahara T, Takigawa M. Hypoxic regulation of stability of connective tissue growth factor/CCN2 mRNA by 3′-untranslated region interacting with a cellular protein in human chondrosarcoma cells. Oncogene 2006; 25: 1099-110.
    • (2006) Oncogene , vol.25 , pp. 1099-1110
    • Kondo, S.1    Kubota, S.2    Mukudai, Y.3    Moritani, N.4    Nishida, T.5    Matsushita, H.6    Matsumoto, S.7    Sugahara, T.8    Takigawa, M.9
  • 100
    • 79956105716 scopus 로고    scopus 로고
    • Ccn6 (wisp3) decreases zeb1-mediated emt and invasion by attenuation of igf-1 receptor signaling in breast cancer
    • Lorenzatti G, Huang W, Pal A, Cabanillas AM, Kleer CG. CCN6 (WISP3) decreases ZEB1-mediated EMT and invasion by attenuation of IGF-1 receptor signaling in breast cancer. J Cell Sci 2011; 124: 1752-8.
    • (2011) J Cell Sci , vol.124 , pp. 1752-1758
    • Lorenzatti, G.1    Huang, W.2    Pal, A.3    Cabanillas, A.M.4    Kleer, C.G.5
  • 101
    • 84863085243 scopus 로고    scopus 로고
    • On how ccn6 suppresses breast cancer growth and invasion
    • Huang W, Pal A, Kleer CG. On how CCN6 suppresses breast cancer growth and invasion. J Cell Commun Signal 2012; 6: 5-10.
    • (2012) J Cell Commun Signal , vol.6 , pp. 5-10
    • Huang, W.1    Pal, A.2    Kleer, C.G.3
  • 105
    • 84888620186 scopus 로고    scopus 로고
    • Ccn2/ctgf attenuates myocardial hypertrophy and cardiac dysfunction upon chronic pressure-overload. Int j cardiol. 2013. In press. 106. Sumiyoshi k, kubota s, furuta ra, yasui k, aoyama e, kawaki h, kawata k, ohgawara t, yamashiro t, takigawa m. Thrombopoietic-mesenchymal interaction that may facilitate both endochondral ossification and platelet maturation via ccn2
    • Gravning J, Ahmed MS, von Lueder TG, Edvardsen T, Attramadal H. CCN2/CTGF attenuates myocardial hypertrophy and cardiac dysfunction upon chronic pressure-overload. Int J Cardiol. 2013. in press. 106. Sumiyoshi K, Kubota S, Furuta RA, Yasui K, Aoyama E, Kawaki H, Kawata K, Ohgawara T, Yamashiro T, Takigawa M. Thrombopoietic-mesenchymal interaction that may facilitate both endochondral ossification and platelet maturation via CCN2. J Cell Commun Signal 2010; 4: 5-14.
    • (2010) J Cell Commun Signal , vol.4 , pp. 5-14
    • Gravning, J.1    Ahmed, M.S.2    Von Lueder, T.G.3    Edvardsen, T.4    Attramadal, H.5
  • 106
    • 34247623492 scopus 로고    scopus 로고
    • Nov (ccn3) functions as a regulator of human hematopoietic stem or progenitor cells
    • Gupta R, Hong D, Iborra F, Sarno S, Enver T. NOV (CCN3) functions as a regulator of human hematopoietic stem or progenitor cells. Science 2007; 316: 590-3.
    • (2007) Science , vol.316 , pp. 590-593
    • Gupta, R.1    Hong, D.2    Iborra, F.3    Sarno, S.4    Enver, T.5
  • 107
    • 60849137834 scopus 로고    scopus 로고
    • Ccn3 -A key regulator of the hematopoietic compartment
    • McCallum L, Irvine AE. CCN3 -A key regulator of the hematopoietic compartment. Blood Rev 2009; 23: 79-85.
    • (2009) Blood Rev , vol.23 , pp. 79-85
    • McCallum, L.1    Irvine, A.E.2
  • 108
    • 0033542768 scopus 로고    scopus 로고
    • Immunohistochemical localization of connective tissue growth factor in the rat central nervous system
    • Kondo Y, Nakanishi T, Takigawa M, Ogawa N. Immunohistochemical localization of connective tissue growth factor in the rat central nervous system. Brain Res 1999; 834: 146-51.
    • (1999) Brain Res , vol.834 , pp. 146-151
    • Kondo, Y.1    Nakanishi, T.2    Takigawa, M.3    Ogawa, N.4
  • 111
    • 28744437870 scopus 로고    scopus 로고
    • Connective tissue growth factor (ctgf) expression in the brain is a downstream effector of insulin resistance-Associated promotion of alzheimer's disease beta-Amyloid neuropathology
    • Zhao Z, Ho L, Wang J, Qin W, Festa ED, Mobbs C, Hof P, Rocher A, Masur S, Haroutunian V, Pasinetti GM. Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance-Associated promotion of Alzheimer's disease beta-Amyloid neuropathology. FASEB J 2005; 19: 2081-2.
    • (2005) FASEB J , vol.19 , pp. 2081-2082
    • Zhao, Z.1    Ho, L.2    Wang, J.3    Qin, W.4    Festa, E.D.5    Mobbs, C.6    Hof, P.7    Rocher, A.8    Masur, S.9    Haroutunian, V.10    Pasinetti, G.M.11
  • 113
    • 84873052754 scopus 로고    scopus 로고
    • Tuberous sclerosis protein 2 (tsc2) modulates ccn4 cytoprotection during apoptotic amyloid toxicity in microglia
    • Shang YC, Chong ZZ, Wang S, Maiese K. Tuberous sclerosis protein 2 (TSC2) modulates CCN4 cytoprotection during apoptotic amyloid toxicity in microglia. Curr Neurovasc Res 2013; 10: 29-38.
    • (2013) Curr Neurovasc Res , vol.10 , pp. 29-138
    • Shang, Y.C.1    Chong, Z.Z.2    Wang, S.3    Maiese, K.4
  • 114
    • 84874256781 scopus 로고    scopus 로고
    • Regulation of pancreatic function by connective tissue growth factor (ctgf, ccn2)
    • Charrier A, Brigstock DR. Regulation of pancreatic function by connective tissue growth factor (CTGF, CCN2). Cytokine Growth Factor Rev 2013; 24: 59-68.
    • (2013) Cytokine Growth Factor Rev , vol.24 , pp. 59-268
    • Charrier, A.1    Brigstock, D.R.2
  • 115
    • 84891371068 scopus 로고    scopus 로고
    • Cysteine-rich protein 61 (ccn1) and connective tissue growth factor (ccn2) at the crosshairs of ocular neovascular and fibrovascular disease therapy
    • Yan L, Chaqour B. Cysteine-rich protein 61 (CCN1) and connective tissue growth factor (CCN2) at the crosshairs of ocular neovascular and fibrovascular disease therapy. J Cell Commun Signal 2013. in press.
    • J Cell Commun Signal 2013. in press
    • Yan, L.1    Chaqour, B.2
  • 117
    • 84864307725 scopus 로고    scopus 로고
    • Ccn2 in orofacial development and remodeling
    • Kubota S. CCN2 in orofacial development and remodeling. Jpn Dent Sci Rev 2012; 48: 101-13.
    • (2012) Jpn Dent Sci Rev , vol.48 , pp. 101-113
    • Kubota, S.1
  • 119
    • 77954243065 scopus 로고    scopus 로고
    • The matricellular protein ccn1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing
    • Jun JI, Lau LF. The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing. Nat Cell Biol 2010; 12: 676-85.
    • (2010) Nat Cell Biol , vol.12 , pp. 676-685
    • Jun, J.I.1    Lau, L.F.2
  • 121
    • 70849136597 scopus 로고    scopus 로고
    • Connective tissue growth factor-(ctgf ccn2)-A marker, mediator and therapeutic target for renal fibrosis
    • Phanish MK, Winn SK, Dockrell ME. Connective tissue growth factor-(CTGF, CCN2) -A marker, mediator and therapeutic target for renal fibrosis. Nephron Exp Nephrol 2010; 114: e83-92.
    • (2010) Nephron Exp Nephrol , vol.114
    • Phanish, M.K.1    Winn, S.K.2    Dockrell, M.E.3
  • 122
    • 79953215255 scopus 로고    scopus 로고
    • The matricellular protein cysteine-rich protein 61 (ccn1/cyr61) enhances physiological adaptation of retinal vessels and reduces pathological neovascularization associated with ischemic retinopathy
    • Hasan A, Pokeza N, Shaw L, Lee HS, Lazzaro D, Chintala H, Rosenbaum D, Grant MB, Chaqour B. The matricellular protein cysteine-rich protein 61 (CCN1/Cyr61) enhances physiological adaptation of retinal vessels and reduces pathological neovascularization associated with ischemic retinopathy. J Biol Chem 2011; 286: 9542-54.
    • (2011) J Biol Chem , vol.286 , pp. 9542-9554
    • Hasan, A.1    Pokeza, N.2    Shaw, L.3    Lee, H.S.4    Lazzaro, D.5    Chintala, H.6    Rosenbaum, D.7    Grant, M.B.8    Chaqour, B.9
  • 123
    • 65649136944 scopus 로고    scopus 로고
    • Ccn3 (nov) is a negative regulator of ccn2 (ctgf) and a novel endogenous inhibitor of the fibrotic pathway in an in vitro model of renal disease
    • Riser BL, Najmabadi F, Perbal B, Peterson DR, Rambow JA, Riser ML, Sukowski E, Yeger H, Riser SC. CCN3 (NOV) is a negative regulator of CCN2 (CTGF) and a novel endogenous inhibitor of the fibrotic pathway in an in vitro model of renal disease. Am J Pathol 2009; 174: 1725-34.
    • (2009) Am J Pathol , vol.174 , pp. 1725-1734
    • Riser, B.L.1    Najmabadi, F.2    Perbal, B.3    Peterson, D.R.4    Rambow, J.A.5    Riser, M.L.6    Sukowski, E.7    Yeger, H.8    Riser, S.C.9
  • 125
    • 80052809211 scopus 로고    scopus 로고
    • Ccn6 as a profibrotic mediator that stimulates the proliferation of lung fibroblasts via the integrin ®1/focal adhesion kinase pathway
    • Batmunkh R, Nishioka Y, Aono Y, Azuma M, Kinoshita K, Kishi J, Makino H, Kishi M, Takezaki A, Sone S. CCN6 as a profibrotic mediator that stimulates the proliferation of lung fibroblasts via the integrin ®1/focal adhesion kinase pathway. J Med Invest 2011; 58: 188-96.
    • (2011) J Med Invest , vol.58 , pp. 188-196
    • Batmunkh, R.1    Nishioka, Y.2    Aono, Y.3    Azuma, M.4    Kinoshita, K.5    Kishi, J.6    Makino, H.7    Kishi, M.8    Takezaki, A.9    Sone, S.10
  • 126
    • 84878975251 scopus 로고    scopus 로고
    • Matricellular protein ccn1 promotes regression of liver fibrosis through induction of cellular senescence in hepatic myofibroblasts
    • Kim KH, Chen CC, Monzon RI, Lau LF. Matricellular protein CCN1 promotes regression of liver fibrosis through induction of cellular senescence in hepatic myofibroblasts. Mol Cell Biol 2013; 33: 2078-90.
    • (2013) Mol Cell Biol , vol.33 , pp. 2078-2090
    • Kim, K.H.1    Chen, C.C.2    Monzon, R.I.3    Lau, L.F.4
  • 128
    • 84874549076 scopus 로고    scopus 로고
    • Ctgf induces monocyte chemoattractant protein-1 expression to enhance monocyte migration in human synovial fibroblasts
    • Liu SC, Hsu CJ, Fong YC, Chuang SM, Tang CH. CTGF induces monocyte chemoattractant protein-1 expression to enhance monocyte migration in human synovial fibroblasts. Biochim Biophys Acta 2013; 1833: 1114-24.
    • (2013) Biochim Biophys Acta , vol.1833 , pp. 1114-1124
    • Liu, S.C.1    Hsu, C.J.2    Fong, Y.C.3    Chuang, S.M.4    Tang, C.H.5
  • 129
    • 60149091505 scopus 로고    scopus 로고
    • Cyr61 increases migration and mmp-13 expression via 〈v®3 integrin, fak, erk and ap-1-dependent pathway in human chondrosarcoma cells
    • Tan TW, Yang WH, Lin YT, Hsu SF, Li TM, Kao ST, Chen WC, Fong YC, Tang CH. Cyr61 increases migration and MMP-13 expression via 〈v®3 integrin, FAK, ERK and AP-1-dependent pathway in human chondrosarcoma cells. Carcinogenesis 2009; 30: 258-68.
    • (2009) Carcinogenesis , vol.30 , pp. 258-268
    • Tan, T.W.1    Yang, W.H.2    Lin, Y.T.3    Hsu, S.F.4    Li, T.M.5    Kao, S.T.6    Chen, W.C.7    Fong, Y.C.8    Tang, C.H.9
  • 130
    • 0036262188 scopus 로고    scopus 로고
    • Connective tissue growth factor increased by hypoxia may initiate angiogenesis in collaboration with matrix metalloproteinases
    • Kondo S, Kubota S, Shimo T, Nishida T, Yosimichi G, Eguchi T, Sugahara T, Takigawa M. Connective tissue growth factor increased by hypoxia may initiate angiogenesis in collaboration with matrix metalloproteinases. Carcinogenesis 2002; 23: 769-76.
    • (2002) Carcinogenesis , vol.23 , pp. 769-776
    • Kondo, S.1    Kubota, S.2    Shimo, T.3    Nishida, T.4    Yosimichi, G.5    Eguchi, T.6    Sugahara, T.7    Takigawa, M.8
  • 131
    • 80053135249 scopus 로고    scopus 로고
    • Ccn3 increases cell motility and mmp-13 expression in human chondrosarcoma through integrindependent pathway
    • Tzeng HE, Chen JC, Tsai CH, Kuo CC, Hsu HC, Hwang WL, Fong YC, Tang CH. CCN3 increases cell motility and MMP-13 expression in human chondrosarcoma through integrindependent pathway. J Cell Physiol 2011; 226: 3181-9.
    • (2011) J Cell Physiol , vol.226 , pp. 3181-3189
    • Tzeng, H.E.1    Chen, J.C.2    Tsai, C.H.3    Kuo, C.C.4    Hsu, H.C.5    Hwang, W.L.6    Fong, Y.C.7    Tang, C.H.8
  • 132
    • 0038175548 scopus 로고    scopus 로고
    • Overexpression of wisp-1 down-regulated motility and invasion of lung cancer cells through inhibition of rac activation
    • Soon LL, Yie TA, Shvarts A, Levine AJ, Su F, Tchou-Wong KM. Overexpression of WISP-1 down-regulated motility and invasion of lung cancer cells through inhibition of Rac activation. J Biol Chem 2003; 278: 11465-70.
    • (2003) J Biol Chem , vol.278 , pp. 11465-11470
    • Soon, L.L.1    Yie, T.A.2    Shvarts, A.3    Levine, A.J.4    Su, F.5    Tchou-Wong, K.M.6
  • 133
    • 54749145426 scopus 로고    scopus 로고
    • Ccn5/wisp-2 expression in breast adenocarcinoma is associated with less frequent progression of the disease and suppresses the invasive phenotypes of tumor cells
    • Banerjee S, Dhar G, Haque I, Kambhampati S, Mehta S, Sengupta K, Tawfik O, Phillips TA, Banerjee SK. CCN5/WISP-2 expression in breast adenocarcinoma is associated with less frequent progression of the disease and suppresses the invasive phenotypes of tumor cells. Cancer Res 2008; 68: 7606-12.
    • (2008) Cancer Res , vol.68 , pp. 7606-7612
    • Banerjee, S.1    Dhar, G.2    Haque, I.3    Kambhampati, S.4    Mehta, S.5    Sengupta, K.6    Tawfik, O.7    Phillips, T.A.8    Banerjee, S.K.9
  • 134
    • 0037474701 scopus 로고    scopus 로고
    • Suppressive effect of overexpressed connective tissue growth factor on tumor cell growth in a human oral squamous cell carcinoma-derived cell line
    • Moritani NH, Kubota S, Nishida T, Kawaki H, Kondo S, Sugahara T, Takigawa M. Suppressive effect of overexpressed connective tissue growth factor on tumor cell growth in a human oral squamous cell carcinoma-derived cell line. Cancer Lett 2003; 192: 205-14.
    • (2003) Cancer Lett , vol.192 , pp. 205-214
    • Moritani, N.H.1    Kubota, S.2    Nishida, T.3    Kawaki, H.4    Kondo, S.5    Sugahara, T.6    Takigawa, M.7
  • 135
    • 84880301279 scopus 로고    scopus 로고
    • Ccn3 promotes prostate cancer bone metastasis by modulating the tumor-bone microenvironment through rankl-dependent pathway
    • Chen PC, Cheng HC, Tang CH. CCN3 promotes prostate cancer bone metastasis by modulating the tumor-bone microenvironment through RANKL-dependent pathway. Carcinogenesis 2013; 34: 1669-79.
    • (2013) Carcinogenesis , vol.34 , pp. 1669-1679
    • Chen, P.C.1    Cheng, H.C.2    Tang, C.H.3
  • 138
    • 84870044156 scopus 로고    scopus 로고
    • Connective tissue growth factor regulates retinal neovascularization through p53 proteindependent transactivation of the matrix metalloproteinase (mmp)-2 gene
    • Chintala H, Liu H, Parmar R, Kamalska M, Kim YJ, Lovett D, Grant MB, Chaqour B. Connective tissue growth factor regulates retinal neovascularization through p53 proteindependent transactivation of the matrix metalloproteinase (MMP)-2 gene. J Biol Chem 2012; 287: 40570-85.
    • (2012) J Biol Chem , vol.287 , pp. 40570-40585
    • Chintala, H.1    Liu, H.2    Parmar, R.3    Kamalska, M.4    Kim, Y.J.5    Lovett, D.6    Grant, M.B.7    Chaqour, B.8
  • 141
    • 1442348817 scopus 로고    scopus 로고
    • Accumulation of nh2-Terminal fragment of connective tissue growth factor in the vitreous of patients with proliferative diabetic retinopathy
    • Hinton DR, Spee C, He S, Weitz S, Usinger W, LaBree L, Oliver N, Lim JI. Accumulation of NH2-Terminal fragment of connective tissue growth factor in the vitreous of patients with proliferative diabetic retinopathy. Diabetes Care 2004; 27: 758-64.
    • (2004) Diabetes Care , vol.27 , pp. 758-764
    • Hinton, D.R.1    Spee, C.2    He, S.3    Weitz, S.4    Usinger, W.5    LaBree, L.6    Oliver, N.7    Lim, J.I.8


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