-
1
-
-
0037392317
-
Proposal for a unified ccn nomenclature
-
Brigstock DR, Goldschmeding R, Katsube K, Lam SCT, Lau LF, Lyons K, Naus C, Perbal B, Riser B, Takigawa M, Yeger H. Proposal for a unified CCN nomenclature. Mol Pathol 2003; 56: 127-8.
-
(2003)
Mol Pathol
, vol.56
, pp. 127-128
-
-
Brigstock, D.R.1
Goldschmeding, R.2
Katsube, K.3
Lam, S.C.T.4
Lau, L.F.5
Lyons, K.6
Naus, C.7
Perbal, B.8
Riser, B.9
Takigawa, M.10
Yeger, H.11
-
3
-
-
33845906843
-
All in the ccn family: Essential matricellular signaling modulators emerge from the bunker
-
Leask A, Abraham DJ. All in the CCN family: essential matricellular signaling modulators emerge from the bunker. J Cell Sci 2006; 119: 4803-10.
-
(2006)
J Cell Sci
, vol.119
, pp. 4803-4810
-
-
Leask, A.1
Abraham, D.J.2
-
4
-
-
33847627603
-
Ccn family proteins and angiogenesis: From embryo to adulthood
-
Kubota S, Takigawa M. CCN family proteins and angiogenesis: from embryo to adulthood. Angiogenesis 2007; 10: 1-11.
-
(2007)
Angiogenesis
, vol.10
, pp. 1-11
-
-
Kubota, S.1
Takigawa, M.2
-
5
-
-
82455198983
-
Taking aim at the extracellular matrix: Ccn proteins as emerging therapeutic targets
-
Jun JI, Lau LF. Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets. Nat Rev Drug Discov 2011; 10: 9459-63.
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 9459-9463
-
-
Jun, J.I.1
Lau, L.F.2
-
6
-
-
79960421230
-
Kallikrein-related peptidase 12 hydrolyzes matricellular proteins of the ccn family and modifies interactions of ccn1 and ccn5 with growth factors
-
Guillon-Munos A, Oikonomopoulou K, Michel N, Smith CR, Petit-Courty A, Canepa S, Reverdiau P, Heuzé-Vourc'h N, Diamandis EP, Courty Y. Kallikrein-related peptidase 12 hydrolyzes matricellular proteins of the CCN family and modifies interactions of CCN1 and CCN5 with growth factors. J Biol Chem 2011; 286: 25505-18.
-
(2011)
J Biol Chem
, vol.286
, pp. 25505-2518
-
-
Guillon-Munos, A.1
Oikonomopoulou, K.2
Michel, N.3
Smith, C.R.4
Petit-Courty, A.5
Canepa, S.6
Reverdiau, P.7
Heuzé-Vourc'h, N.8
Diamandis, E.P.9
Courty, Y.10
-
7
-
-
0037183997
-
Matrix metalloproteinases cleave connective tissue growth factor and reactivate angiogenic activity of vascular endothelial growth factor 165
-
Hashimoto G, Inoki I, Fujii Y, Aoki T, Ikeda E, Okada Y. Matrix metalloproteinases cleave connective tissue growth factor and reactivate angiogenic activity of vascular endothelial growth factor 165. J Biol Chem 2002; 277: 36288-95.
-
(2002)
J Biol Chem
, vol.277
, pp. 36288-362895
-
-
Hashimoto, G.1
Inoki, I.2
Fujii, Y.3
Aoki, T.4
Ikeda, E.5
Okada, Y.6
-
8
-
-
78649449540
-
Connective tissue growth factor is a substrate of adam28
-
Mochizuki S, Tanaka R, Shimoda M, Onuma J, Fujii Y, Jinno H, Okada Y. Connective tissue growth factor is a substrate of ADAM28. Biochem Biophys Res Commun 2010; 402: 651-7.
-
(2010)
Biochem Biophys Res Commun
, vol.402
, pp. 651-657
-
-
Mochizuki, S.1
Tanaka, R.2
Shimoda, M.3
Onuma, J.4
Fujii, Y.5
Jinno, H.6
Okada, Y.7
-
9
-
-
33947219834
-
Expression and physiological role of ccn4/wnt-induced secreted protein 1 mrna splicing variants in chondrocytes
-
Yanagita T, Kubota S, Kawaki H, Kawata K, Kondo S, Takano-Yamamoto T, Tanaka S, Takigawa M. Expression and physiological role of CCN4/Wnt-induced secreted protein 1 mRNA splicing variants in chondrocytes. FEBS J 2007; 274: 1655-65.
-
(2007)
FEBS J
, vol.274
, pp. 1655-1665
-
-
Yanagita, T.1
Kubota, S.2
Kawaki, H.3
Kawata, K.4
Kondo, S.5
Takano-Yamamoto, T.6
Tanaka, S.7
Takigawa, M.8
-
10
-
-
84857791001
-
Adhesion-modulating/matricellular ecm protein families: A structural, functional and evolutionary appraisal
-
Mosher DF, Adams JC. Adhesion-modulating/matricellular ECM protein families: a structural, functional and evolutionary appraisal. Matrix Biol 2012; 31: 155-61.
-
(2012)
Matrix Biol
, vol.31
, pp. 155-1561
-
-
Mosher, D.F.1
Adams, J.C.2
-
11
-
-
79959351079
-
First structural glimpse of ccn3 and ccn5 multifunctional signaling regulators elucidated by small angle x-ray scattering
-
Holbourn KP, Malfois M, Acharya KR. First structural glimpse of CCN3 and CCN5 multifunctional signaling regulators elucidated by small angle x-ray scattering. J Biol Chem 2011; 286: 22243-9.
-
(2011)
J Biol Chem
, vol.286
, pp. 22243-22249
-
-
Holbourn, K.P.1
Malfois, M.2
Acharya, K.R.3
-
12
-
-
84866344934
-
Roles of heterotypic ccn2/ctgf-ccn3/nov and homotypic ccn2-ccn2 interactions in expression of the differentiated phenotype of chondrocytes
-
Hoshijima M, Hattori T, Aoyama E, Nishida T, Yamashiro T, Takigawa M. Roles of heterotypic CCN2/CTGF-CCN3/NOV and homotypic CCN2-CCN2 interactions in expression of the differentiated phenotype of chondrocytes. FEBS J 2012; 279: 3584-97.
-
(2012)
FEBS J
, vol.279
, pp. 3584-3597
-
-
Hoshijima, M.1
Hattori, T.2
Aoyama, E.3
Nishida, T.4
Yamashiro, T.5
Takigawa, M.6
-
13
-
-
84862095866
-
Cyr61 induces il-6 production by fibroblast-like synoviocytes promoting th17 differentiation in rheumatoid arthritis
-
Lin J, Zhou Z, Huo R, Xiao L, Ouyang G, Wang L, Sun Y, Shen B, Li D, Li N. Cyr61 induces IL-6 production by fibroblast-like synoviocytes promoting Th17 differentiation in rheumatoid arthritis. J Immunol 2012; 188: 5776-84.
-
(2012)
J Immunol
, vol.188
, pp. 5776-5784
-
-
Lin, J.1
Zhou, Z.2
Huo, R.3
Xiao, L.4
Ouyang, G.5
Wang, L.6
Sun, Y.7
Shen, B.8
Li, D.9
Li, N.10
-
14
-
-
1542305557
-
Connective tissue growth factor (ccn2) induces adhesion of rat activated hepatic stellate cells by binding of its c-Terminal domain to integrin 〈(v)®(3) and heparan sulfate proteoglycan
-
Gao R, Brigstock DR. Connective tissue growth factor (CCN2) induces adhesion of rat activated hepatic stellate cells by binding of its C-Terminal domain to integrin 〈(v)®(3) and heparan sulfate proteoglycan. J Biol Chem 2004; 279: 8848-55.
-
(2004)
J Biol Chem
, vol.279
, pp. 8848-8855
-
-
Gao, R.1
Brigstock, D.R.2
-
15
-
-
84857154364
-
Tnf〈-induced apoptosis enabled by ccn1/cyr61: Pathways of reactive oxygen species generation and cytochrome c release
-
Juric V, Chen CC, Lau LF. TNF〈-induced apoptosis enabled by CCN1/CYR61: pathways of reactive oxygen species generation and cytochrome c release. PLoS One 2012; 7: e31303.
-
(2012)
PLoS One
, vol.7
-
-
Juric, V.1
Chen, C.C.2
Lau, L.F.3
-
16
-
-
77949674681
-
Cyr61/ ccn1 displays high-Affinity binding to the somatomedin b(1-44) domain of vitronectin
-
Francischetti IM, Kotsyfakis M, Andersen JF, Lukszo J. Cyr61/ CCN1 displays high-Affinity binding to the somatomedin B(1-44) domain of vitronectin. PLoS One 2010; 5: e9356.
-
(2010)
PLoS One
, vol.5
-
-
Francischetti, I.M.1
Kotsyfakis, M.2
Andersen, J.F.3
Lukszo, J.4
-
18
-
-
84870834470
-
Ctgf increases il-6 expression in human synovial fibroblasts through integrin-dependent signaling pathway
-
Liu SC, Hsu CJ, Chen HT, Tsou HK, Chuang SM, Tang CH. CTGF increases IL-6 expression in human synovial fibroblasts through integrin-dependent signaling pathway. PLoS One 2012; 7: e51097.
-
(2012)
PLoS One
, vol.7
-
-
Liu, S.C.1
Hsu, C.J.2
Chen, H.T.3
Tsou, H.K.4
Chuang, S.M.5
Tang, C.H.6
-
19
-
-
84869102065
-
Role of lrp1 in transport of ccn2 protein in chondrocytes
-
Kawata K, Kubota S, Eguchi T, Aoyama E, Moritani NH, Kondo S, Nishida T, Takigawa M. Role of LRP1 in transport of CCN2 protein in chondrocytes. J Cell Sci 2012; 125: 2965-72.
-
(2012)
J Cell Sci
, vol.125
, pp. 2965-2972
-
-
Kawata, K.1
Kubota, S.2
Eguchi, T.3
Aoyama, E.4
Moritani, N.H.5
Kondo, S.6
Nishida, T.7
Takigawa, M.8
-
20
-
-
66949129054
-
N-Terminal domains of ccn family 2/connective tissue growth factor bind to aggrecan
-
Aoyama E, Hattori T, Hoshijima M, Araki D, Nishida T, Kubota S, Takigawa M. N-Terminal domains of CCN family 2/connective tissue growth factor bind to aggrecan. Biochem J 2009; 420: 413-20.
-
(2009)
Biochem J
, vol.420
, pp. 413-420
-
-
Aoyama, E.1
Hattori, T.2
Hoshijima, M.3
Araki, D.4
Nishida, T.5
Kubota, S.6
Takigawa, M.7
-
21
-
-
80055016472
-
The role of ccn2 in cartilage and bone development
-
Kubota S, Takigawa M. The role of CCN2 in cartilage and bone development. J Cell Commun Signal 2011; 5: 209-17.
-
(2011)
J Cell Commun Signal
, vol.5
, pp. 209-517
-
-
Kubota, S.1
Takigawa, M.2
-
22
-
-
84880324961
-
A novel role of ccn2 in rank/rankl/opg signaling
-
Aoyama E, Kubota S, Nishida T, Takigawa M. A novel role of CCN2 in RANK/RANKL/OPG signaling. J Dent Res 2013; 92: Special issue A: 1329.
-
(2013)
J Dent Res
, vol.92
, Issue.A
, pp. 1329
-
-
Aoyama, E.1
Kubota, S.2
Nishida, T.3
Takigawa, M.4
-
23
-
-
79551483244
-
Ctgf/ccn2 activates canonical wnt signalling in mesangial cells through lrp6: Implications for the pathogenesis of diabetic nephropathy
-
Rooney B, O'Donovan H, Gaffney A, Browne M, Faherty N, Curran SP, Sadlier D, Godson C, Brazil DP, Crean J. CTGF/CCN2 activates canonical Wnt signalling in mesangial cells through LRP6: implications for the pathogenesis of diabetic nephropathy. FEBS Lett 2011; 585: 531-8.
-
(2011)
FEBS Lett
, vol.585
, pp. 531-538
-
-
Rooney, B.1
O'Donovan, H.2
Gaffney, A.3
Browne, M.4
Faherty, N.5
Curran, S.P.6
Sadlier, D.7
Godson, C.8
Brazil, D.P.9
Crean, J.10
-
24
-
-
84872867267
-
Lrp-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by dkk-1
-
Ren S, Johnson BG, Kida Y, Ip C, Davidson KC, Lin SL, Kobayashi A, Lang RA, Hadjantonakis AK, Moon RT, Duffield JS. LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1. Proc Natl Acad Sci USA 2013; 110: 1440-5.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 1440-1445
-
-
Ren, S.1
Johnson, B.G.2
Kida, Y.3
Ip, C.4
Davidson, K.C.5
Lin, S.L.6
Kobayashi, A.7
Lang, R.A.8
Hadjantonakis, A.K.9
Moon, R.T.10
Duffield, J.S.11
-
25
-
-
84865492920
-
Hyperglycemia causes renal cell damage via ccn2-induced activation of the trka receptor
-
Fragiadaki M, Hill N, Hewitt R, Bou-Gharios G, Cook T, Tam FW, Domin J, Mason RM. Hyperglycemia causes renal cell damage via CCN2-induced activation of the TrkA receptor. Diabetes 2012; 61: 2280-8.
-
(2012)
Diabetes
, vol.61
, pp. 2280-2288
-
-
Fragiadaki, M.1
Hill, N.2
Hewitt, R.3
Bou-Gharios, G.4
Cook, T.5
Tam, F.W.6
Domin, J.7
Mason, R.M.8
-
26
-
-
84870491182
-
Ccn2/ctgf binds to fibroblast growth factor receptor 2 and modulates its signaling
-
Aoyama E, Kubota S, Takigawa M. CCN2/CTGF binds to fibroblast growth factor receptor 2 and modulates its signaling. FEBS Lett 2012; 586: 4270-5.
-
(2012)
FEBS Lett
, vol.586
, pp. 4270-4275
-
-
Aoyama, E.1
Kubota, S.2
Takigawa, M.3
-
27
-
-
59449095447
-
Ccn family 2/connective tissue growth factor modulates bmp signalling as a signal conductor, which action regulates the proliferation and differentiation of chondrocytes
-
Maeda A, Nishida T, Aoyama E, Kubota S, Lyons KM, Kuboki T, Takigawa M. CCN family 2/connective tissue growth factor modulates BMP signalling as a signal conductor, which action regulates the proliferation and differentiation of chondrocytes. J Biochem 2009; 145: 207-16.
-
(2009)
J Biochem
, vol.145
, pp. 207-216
-
-
Maeda, A.1
Nishida, T.2
Aoyama, E.3
Kubota, S.4
Lyons, K.M.5
Kuboki, T.6
Takigawa, M.7
-
28
-
-
80054894825
-
Effect of ccn2 on fgf2-induced proliferation and mmp9 and mmp13 productions by chondrocytes
-
Nishida T, Kubota S, Aoyama E, Janune D, Maeda A, Takigawa M. Effect of CCN2 on FGF2-induced proliferation and MMP9 and MMP13 productions by chondrocytes. Endocrinology 2011; 182: 4232-41.
-
(2011)
Endocrinology
, vol.182
, pp. 4232-4241
-
-
Nishida, T.1
Kubota, S.2
Aoyama, E.3
Janune, D.4
Maeda, A.5
Takigawa, M.6
-
29
-
-
84864754659
-
Ccn2/ctgf regulates neovessel formation via targeting structurally conserved cystine knot motifs in multiple angiogenic regulators
-
Pi L, Shenoy AK, Liu J, Kim S, Nelson N, Xia H, Hauswirth WW, Petersen BE, Schultz GS, Scott EW. CCN2/CTGF regulates neovessel formation via targeting structurally conserved cystine knot motifs in multiple angiogenic regulators. FASEB J 2012; 26: 3365-79.
-
(2012)
FASEB J
, vol.26
, pp. 3365-3379
-
-
Pi, L.1
Shenoy, A.K.2
Liu, J.3
Kim, S.4
Nelson, N.5
Xia, H.6
Hauswirth, W.W.7
Petersen, B.E.8
Schultz, G.S.9
Scott, E.W.10
-
30
-
-
84856184857
-
The wnt antagonist wif-1 interacts with ctgf and inhibits ctgf activity
-
Surmann-Schmitt C, Sasaki T, Hattori T, Eitzinger N, Schett G, von der Mark K, Stock M. The Wnt antagonist Wif-1 interacts with CTGF and inhibits CTGF activity. J Cell Physiol 2012; 227: 2207-16.
-
(2012)
J Cell Physiol
, vol.227
, pp. 2207-2216
-
-
Surmann-Schmitt, C.1
Sasaki, T.2
Hattori, T.3
Eitzinger, N.4
Schett, G.5
Von Der Mark, K.6
Stock, M.7
-
31
-
-
84872593277
-
Ccn4 induces il-6 production through 〈v®5 receptor, pi3k, akt, and nf-|b singling pathway in human synovial fibroblasts
-
Hou CH, Tang CH, Hsu CJ, Hou SM, Liu JF. CCN4 induces IL-6 production through 〈v®5 receptor, PI3K, Akt, and NF-|B singling pathway in human synovial fibroblasts. Arthritis Res Ther 2013; 15: R19.
-
(2013)
Arthritis Res Ther
, vol.15
-
-
Hou, C.H.1
Tang, C.H.2
Hsu, C.J.3
Hou, S.M.4
Liu, J.F.5
-
32
-
-
79961126182
-
Wisp2/ccn5 up-regulated in the central nervous system of gm3-only mice facilitates neurite formation in neuro2a cells via integrin-Akt signaling
-
Ohkawa Y, Ohmi Y, Tajima O, Yamauchi Y, Furukawa K, Furukawa K. Wisp2/CCN5 up-regulated in the central nervous system of GM3-only mice facilitates neurite formation in Neuro2a cells via integrin-Akt signaling. Biochem Biophys Res Commun 2011; 411: 483-9.
-
(2011)
Biochem Biophys Res Commun
, vol.411
, pp. 483-489
-
-
Ohkawa, Y.1
Ohmi, Y.2
Tajima, O.3
Yamauchi, Y.4
Furukawa, K.5
Furukawa, K.6
-
33
-
-
80054897689
-
Ccn6 enhances icam-1 expression and cell motility in human chondrosarcoma cells
-
Fong YC, Lin CY, Su YC, Chen WC, Tsai FJ, Tsai CH, Huang CY, Tang CH. CCN6 enhances ICAM-1 expression and cell motility in human chondrosarcoma cells. J Cell Physiol 2012; 227: 223-32.
-
(2012)
J Cell Physiol
, vol.227
, pp. 223-232
-
-
Fong, Y.C.1
Lin, C.Y.2
Su, Y.C.3
Chen, W.C.4
Tsai, F.J.5
Tsai, C.H.6
Huang, C.Y.7
Tang, C.H.8
-
34
-
-
78650936271
-
Wisp-1/ccn4 regulates osteogenesis by enhancing bmp-2 activity
-
Ono M, Inkson CA, Kilts TM, Young MF. WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity. J Bone Miner Res 2011; 26: 193-208.
-
(2011)
J Bone Miner Res
, vol.26
, pp. 193-208
-
-
Ono, M.1
Inkson, C.A.2
Kilts, T.M.3
Young, M.F.4
-
35
-
-
84866356504
-
Ccn6 modulates bmp signaling via the smad-independent tak1/p38 pathway, acting to suppress metastasis of breast cancer
-
Pal A, Huang W, Li X, Toy KA, Nikolovska-Coleska Z, Kleer CG. CCN6 modulates BMP signaling via the Smad-independent TAK1/p38 pathway, acting to suppress metastasis of breast cancer. Cancer Res 2012; 72: 4818-28.
-
(2012)
Cancer Res
, vol.72
, pp. 4818-4828
-
-
Pal, A.1
Huang, W.2
Li, X.3
Toy, K.A.4
Nikolovska-Coleska, Z.5
Kleer, C.G.6
-
36
-
-
34948831652
-
The ccn family member wisp3, mutant in progressive pseudorheumatoid dysplasia, modulates bmp and wnt signaling
-
Nakamura Y, Weidinger G, Liang JO, Aquilina-Beck A, Tamai K, Moon RT, Warman ML. The CCN family member Wisp3, mutant in progressive pseudorheumatoid dysplasia, modulates BMP and Wnt signaling. J Clin Invest 2007; 117: 3075-86.
-
(2007)
J Clin Invest
, vol.117
, pp. 3075-3086
-
-
Nakamura, Y.1
Weidinger, G.2
Liang, J.O.3
Aquilina-Beck, A.4
Tamai, K.5
Moon, R.T.6
Warman, M.L.7
-
37
-
-
84877992436
-
Wisp3-igf1 interaction regulates chondrocyte hypertrophy
-
Repudi SR, Patra M, Sen M. WISP3-IGF1 interaction regulates chondrocyte hypertrophy. J Cell Sci 2013; 126: 1650-8.
-
(2013)
J Cell Sci
, vol.126
, pp. 1650-1658
-
-
Repudi, S.R.1
Patra, M.2
Sen, M.3
-
39
-
-
79951517589
-
The ccn family: A new class of inflammation modulators?
-
Kular L, Pakradouni J, Kitabgi P, Laurent M, Martinerie C. The CCN family: a new class of inflammation modulators? Biochimie 2011; 93: 377-88.
-
(2011)
Biochimie
, vol.93
, pp. 377-388
-
-
Kular, L.1
Pakradouni, J.2
Kitabgi, P.3
Laurent, M.4
Martinerie, C.5
-
40
-
-
33750169244
-
Comparable response of ccn1 with ccn2 genes upon arthritis: An in vitro evaluation with a human chondrocytic cell line stimulated by a set of cytokines
-
Moritani NH, Kubota S, Sugahara T, Takigawa M. Comparable response of ccn1 with ccn2 genes upon arthritis: an in vitro evaluation with a human chondrocytic cell line stimulated by a set of cytokines. Cell Commun Signal 2005; 3: 6.
-
(2005)
Cell Commun Signal
, vol.3
, pp. 6
-
-
Moritani, N.H.1
Kubota, S.2
Sugahara, T.3
Takigawa, M.4
-
41
-
-
84866386719
-
Glucocorticoids induce ccn5/wisp-2 expression and attenuate invasion in oestrogen receptor-negative human breast cancer cells
-
Ferrand N, Stragier E, Redeuilh G, Sabbah M. Glucocorticoids induce CCN5/WISP-2 expression and attenuate invasion in oestrogen receptor-negative human breast cancer cells. Biochem J 2012; 447: 71-9.
-
(2012)
Biochem J
, vol.447
, pp. 71-79
-
-
Ferrand, N.1
Stragier, E.2
Redeuilh, G.3
Sabbah, M.4
-
42
-
-
33644643752
-
Dexamethasone induces connective tissue growth factor expression in renal tubular epithelial cells in a mouse strain-specific manner
-
Okada H, Kikuta T, Inoue T, Kanno Y, Ban S, Sugaya T, Takigawa M, Suzuki H. Dexamethasone induces connective tissue growth factor expression in renal tubular epithelial cells in a mouse strain-specific manner. Am J Pathol 2006; 168: 737-47.
-
(2006)
Am J Pathol
, vol.168
, pp. 737-747
-
-
Okada, H.1
Kikuta, T.2
Inoue, T.3
Kanno, Y.4
Ban, S.5
Sugaya, T.6
Takigawa, M.7
Suzuki, H.8
-
43
-
-
33644913383
-
Contrasting role of phospholipase c-©1 in the expression of immediate early genes induced by epidermal or platelet-derived growth factors
-
Liao HJ, de Los Santos J, Carpenter G. Contrasting role of phospholipase C-©1 in the expression of immediate early genes induced by epidermal or platelet-derived growth factors. Exp Cell Res 2006; 312: 807-16.
-
(2006)
Exp Cell Res
, vol.312
, pp. 807-816
-
-
Liao, H.J.1
De Los Santos, J.2
Carpenter, G.3
-
44
-
-
80055009055
-
Substance p induces ccn1 expression via histone deacetylase activity in human colonic epithelial cells
-
Koon HW, Shih DQ, Hing TC, Chen J, Ho S, Zhao D, Targan SR, Pothoulakis C. Substance P induces CCN1 expression via histone deacetylase activity in human colonic epithelial cells. Am J Pathol 2011; 179: 2315-26.
-
(2011)
Am J Pathol
, vol.179
, pp. 2315-2326
-
-
Koon, H.W.1
Shih, D.Q.2
Hing, T.C.3
Chen, J.4
Ho, S.5
Zhao, D.6
Targan, S.R.7
Pothoulakis, C.8
-
45
-
-
79956024624
-
Ccn1, a candidate target for zoledronic acid treatment in breast cancer
-
Espinoza I, Liu H, Busby R, Lupu R. CCN1, a candidate target for zoledronic acid treatment in breast cancer. Mol Cancer Ther 2011; 10: 732-41.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 732-741
-
-
Espinoza, I.1
Liu, H.2
Busby, R.3
Lupu, R.4
-
46
-
-
81455141243
-
Cigarette smokeinduced early growth response-1 regulates the expression of the cysteine-rich 61 in human skin dermal fibroblasts
-
Kim JN, Kim HJ, Jeong SH, Kye YC, Son SW. Cigarette smokeinduced early growth response-1 regulates the expression of the cysteine-rich 61 in human skin dermal fibroblasts. Exp Dermatol 2011; 20: 992-7.
-
(2011)
Exp Dermatol
, vol.20
, pp. 992-997
-
-
Kim, J.N.1
Kim, H.J.2
Jeong, S.H.3
Kye, Y.C.4
Son, S.W.5
-
47
-
-
84864320125
-
Angiotensin ii increases ctgf expression via mapks/tgf-®1/ traf6 pathway in atrial fibroblasts
-
Gu J, Liu X, Wang QX, Tan HW, Guo M, Jiang WF, Zhou L. Angiotensin II increases CTGF expression via MAPKs/TGF-®1/ TRAF6 pathway in atrial fibroblasts. Exp Cell Res 2012; 318: 2105-15.
-
(2012)
Exp Cell Res
, vol.318
, pp. 2105-215
-
-
Gu, J.1
Liu, X.2
Wang, Q.X.3
Tan, H.W.4
Guo, M.5
Jiang, W.F.6
Zhou, L.7
-
48
-
-
84871765176
-
A physiological role for connective tissue growth factor in early wound healing
-
Alfaro MP, Deskins DL, Wallus M, DasGupta J, Davidson JM, Nanney LB, A Guney M, Gannon M, Young PP. A physiological role for connective tissue growth factor in early wound healing. Lab Invest 2013; 93: 81-95.
-
(2013)
Lab Invest
, vol.93
, pp. 81-995
-
-
Alfaro, M.P.1
Deskins, D.L.2
Wallus, M.3
DasGupta, J.4
Davidson, J.M.5
Nanney, L.B.6
Guney, A.M.7
Gannon, M.8
Young, P.P.9
-
49
-
-
84861176253
-
Antiproliferative factor regulates connective tissue growth factor (ctgf/ccn2) expression in t24 bladder carcinoma cells
-
Matika CA, Wasilewski M, Arnott JA, Planey SL. Antiproliferative factor regulates connective tissue growth factor (CTGF/CCN2) expression in T24 bladder carcinoma cells. Mol Biol Cell 2012; 23: 1976-85.
-
(2012)
Mol Biol Cell
, vol.23
, pp. 1976-1985
-
-
Matika, C.A.1
Wasilewski, M.2
Arnott, J.A.3
Planey, S.L.4
-
50
-
-
84871953130
-
Thrombin-induced ccn2 expression in human lung fibroblasts requires the c-src/jak2/ stat3 pathway
-
Bai KJ, Chen BC, Pai HC, Weng CM, Yu CC, Hsu MJ, Yu MC, Ma HP, Wu CH, Hong CY, Kuo ML, Lin CH. Thrombin-induced CCN2 expression in human lung fibroblasts requires the c-Src/JAK2/ STAT3 pathway. J Leukoc Biol 2013; 93: 101-12.
-
(2013)
J Leukoc Biol
, vol.93
, pp. 101-112
-
-
Bai, K.J.1
Chen, B.C.2
Pai, H.C.3
Weng, C.M.4
Yu, C.C.5
Hsu, M.J.6
Yu, M.C.7
Ma, H.P.8
Wu, C.H.9
Hong, C.Y.10
Kuo, M.L.11
Lin, C.H.12
-
51
-
-
84866698740
-
Ifn-© and tnf-〈 synergize to inhibit ctgf expression in human lung endothelial cells
-
Laug R, Fehrholz M, Schütze N, Kramer BW, Krump-Konvalinkova V, Speer CP, Kunzmann S. IFN-© and TNF-〈 synergize to inhibit CTGF expression in human lung endothelial cells. PLoS One 2012; 7: e45430.
-
(2012)
PLoS One
, vol.7
-
-
Laug, R.1
Fehrholz, M.2
Schütze, N.3
Kramer, B.W.4
Krump-Konvalinkova, V.5
Speer, C.P.6
Kunzmann, S.7
-
52
-
-
84871085082
-
Curcumin inhibits thrombin-stimulated connective tissue growth factor (ctgf/ccn2) production through c-jun nh2-Terminal kinase suppression in human gingival fibroblasts
-
Chen YW, Yang WH, Wong MY, Chang HH, Yen-Ping Kuo M. Curcumin inhibits thrombin-stimulated connective tissue growth factor (CTGF/CCN2) production through c-Jun NH2-Terminal kinase suppression in human gingival fibroblasts. J Periodontol 2012; 83: 1546-53.
-
(2012)
J Periodontol
, vol.83
, pp. 1546-1553
-
-
Chen, Y.W.1
Yang, W.H.2
Wong, M.Y.3
Chang, H.H.4
Yen-Ping Kuo, M.5
-
53
-
-
84879164669
-
Curcumin inhibits tgf®1-induced ccn2 via src, jnk, and smad3 in gingiva
-
Yang WH, Kuo MY, Liu CM, Deng YT, Chang HH, Chang JZ. Curcumin inhibits TGF®1-induced CCN2 via Src, JNK, and Smad3 in gingiva. J Dent Res 2013; 92: 629-34.
-
(2013)
J Dent Res
, vol.92
, pp. 629-634
-
-
Yang, W.H.1
Kuo, M.Y.2
Liu, C.M.3
Deng, Y.T.4
Chang, H.H.5
Chang, J.Z.6
-
54
-
-
72449142340
-
Nicotine-induced ccn2: From smoking to periodontal fibrosis
-
Takeuchi H, Kubota S, Murakashi E, Zhou Y, Endo K, Ng PS, Takigawa M, Numabe Y. Nicotine-induced CCN2: from smoking to periodontal fibrosis. J Dent Res 2010; 89: 34-9.
-
(2010)
J Dent Res
, vol.89
, pp. 34-89
-
-
Takeuchi, H.1
Kubota, S.2
Murakashi, E.3
Zhou, Y.4
Endo, K.5
Ng, P.S.6
Takigawa, M.7
Numabe, Y.8
-
55
-
-
84055222551
-
Ccn2 promotes cigarette smoke-induced proliferation of rat pulmonary artery smooth muscle cells through upregulating cyclin d1 expression
-
Wang R, Xu YJ, Liu XS, Zeng DX, Xiang M. CCN2 promotes cigarette smoke-induced proliferation of rat pulmonary artery smooth muscle cells through upregulating cyclin D1 expression. J Cell Biochem 2012; 113: 349-59.
-
(2012)
J Cell Biochem
, vol.113
, pp. 349-359
-
-
Wang, R.1
Xu, Y.J.2
Liu, X.S.3
Zeng, D.X.4
Xiang, M.5
-
56
-
-
41149162565
-
Novel transcription-factor-like function of human matrix metalloproteinase 3 regulating the ctgf/ccn2 gene
-
Eguchi T, Kubota S, Kawata K, Mukudai Y, Uehara J, Ohgawara T, Ibaragi S, Sasaki A, Kuboki T, Takigawa M. Novel transcription-factor-like function of human matrix metalloproteinase 3 regulating the CTGF/CCN2 gene. Mol Cell Biol 2008; 28: 2391-413.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 2391-2413
-
-
Eguchi, T.1
Kubota, S.2
Kawata, K.3
Mukudai, Y.4
Uehara, J.5
Ohgawara, T.6
Ibaragi, S.7
Sasaki, A.8
Kuboki, T.9
Takigawa, M.10
-
57
-
-
84857539208
-
Mmp-3 provokes ctgf/ccn2 production independently of protease activity and dependently on dynamin-related endocytosis, which contributes to human dental pulp cell migration
-
Muromachi K, Kamio N, Narita T, Annen-Kamio M, Sugiya H, Matsushima K. MMP-3 provokes CTGF/CCN2 production independently of protease activity and dependently on dynamin-related endocytosis, which contributes to human dental pulp cell migration. J Cell Biochem 2012; 113: 1348-58.
-
(2012)
J Cell Biochem
, vol.113
, pp. 1348-1358
-
-
Muromachi, K.1
Kamio, N.2
Narita, T.3
Annen-Kamio, M.4
Sugiya, H.5
Matsushima, K.6
-
58
-
-
77958481136
-
The gene encoding the hematopoietic stem cell regulator ccn3/nov is under direct cytokine control through the transcription factors stat5a/b
-
Kimura A, Martin C, Robinson GW, Simone JM, Chen W, Wickre MC, O'Shea JJ, Hennighausen L. The gene encoding the hematopoietic stem cell regulator CCN3/NOV is under direct cytokine control through the transcription factors STAT5A/B. J Biol Chem 2010; 285: 32704-9.
-
(2010)
J Biol Chem
, vol.285
, pp. 32704-32709
-
-
Kimura, A.1
Martin, C.2
Robinson, G.W.3
Simone, J.M.4
Chen, W.5
Wickre, M.C.6
O'Shea, J.J.7
Hennighausen, L.8
-
59
-
-
84862001701
-
Inhibition of fibroblast growth by notch1 signaling is mediated by induction of wnt11-dependent wisp-1
-
Liu ZJ, Li Y, Tan Y, Xiao M, Zhang J, Radtke F, Velazquez OC. Inhibition of fibroblast growth by Notch1 signaling is mediated by induction of Wnt11-dependent WISP-1. PLoS One 2012; 7: e38811.
-
(2012)
PLoS One
, vol.7
-
-
Liu, Z.J.1
Li, Y.2
Tan, Y.3
Xiao, M.4
Zhang, J.5
Radtke, F.6
Velazquez, O.C.7
-
60
-
-
64149116677
-
Nitric oxide increases wnt-induced secreted protein-1 (wisp-1/ccn4) expression and function in colitis
-
Wang H, Zhang R, Wen S, McCafferty DM, Beck PL, MacNaughton WK. Nitric oxide increases Wnt-induced secreted protein-1 (WISP-1/CCN4) expression and function in colitis. J Mol Med (Berl) 2009; 87: 435-45.
-
(2009)
J Mol Med (Berl
, vol.87
, pp. 435-445
-
-
Wang, H.1
Zhang, R.2
Wen, S.3
McCafferty, D.M.4
Beck, P.L.5
MacNaughton, W.K.6
-
61
-
-
84865702908
-
The food contaminant and nephrotoxin ochratoxin a enhances wnt1 inducible signaling protein 1 and tumor necrosis factor-〈 expression in human primary proximal tubule cells
-
Hennemeier I, Humpf HU, Gekle M, Schwerdt G. The food contaminant and nephrotoxin ochratoxin A enhances Wnt1 inducible signaling protein 1 and tumor necrosis factor-〈 expression in human primary proximal tubule cells. Mol Nutr Food Res 2012; 56: 1375-84.
-
(2012)
Mol Nutr Food Res
, vol.56
, pp. 1375-1384
-
-
Hennemeier, I.1
Humpf, H.U.2
Gekle, M.3
Schwerdt, G.4
-
62
-
-
33847712503
-
Insulin-like growth factor-1 (igf-1) induces wisp-2/ccn5 via multiple molecular cross-Talks and is essential for mitogenic switch by igf-1 axis in estrogen receptor-positive breast tumor cells
-
Dhar K, Banerjee S, Dhar G, Sengupta K, Banerjee SK. Insulin-like growth factor-1 (IGF-1) induces WISP-2/CCN5 via multiple molecular cross-Talks and is essential for mitogenic switch by IGF-1 axis in estrogen receptor-positive breast tumor cells. Cancer Res 2007; 67: 1520-6.
-
(2007)
Cancer Res
, vol.67
, pp. 1520-1526
-
-
Dhar, K.1
Banerjee, S.2
Dhar, G.3
Sengupta, K.4
Banerjee, S.K.5
-
63
-
-
33746751471
-
Mechanical regulation of the cyr61/ccn1 and ctgf/ccn2 proteins
-
Chaqour B, Goppelt-Struebe M. Mechanical regulation of the Cyr61/CCN1 and CTGF/CCN2 proteins. FEBS J 2006; 273: 3639-49.
-
(2006)
FEBS J
, vol.273
, pp. 3639-3649
-
-
Chaqour, B.1
Goppelt-Struebe, M.2
-
64
-
-
84874105864
-
Promotion of ccn2 expression and osteoblastic differentiation by actin polymerization, which is induced by laminar fluid flow stress
-
Honjo T, Kubota S, Kamioka H, Sugawara Y, Ishihara Y, Yamashiro T, Takigawa M, Takano-Yamamoto T. Promotion of Ccn2 expression and osteoblastic differentiation by actin polymerization, which is induced by laminar fluid flow stress. J Cell Commun Signal 2012; 6: 225-32.
-
(2012)
J Cell Commun Signal
, vol.6
, pp. 225-632
-
-
Honjo, T.1
Kubota, S.2
Kamioka, H.3
Sugawara, Y.4
Ishihara, Y.5
Yamashiro, T.6
Takigawa, M.7
Takano-Yamamoto, T.8
-
65
-
-
80053591738
-
The effects of low-intensity pulsed ultrasound exposure on gingival cells
-
Shiraishi R, Masaki C, Toshinaga A, Okinaga T, Nishihara T, Yamanaka N, Nakamoto T, Hosokawa R. The effects of low-intensity pulsed ultrasound exposure on gingival cells. J Periodontol 2011; 82: 1498-503.
-
(2011)
J Periodontol
, vol.82
, pp. 1498-1503
-
-
Shiraishi, R.1
Masaki, C.2
Toshinaga, A.3
Okinaga, T.4
Nishihara, T.5
Yamanaka, N.6
Nakamoto, T.7
Hosokawa, R.8
-
66
-
-
84859977089
-
Ets-1 is essential for connective tissue growth factor (ctgf/ ccn2) induction by tgf-®1 in osteoblasts
-
Geisinger MT, Astaiza R, Butler T, Popoff SN, Planey SL, Arnott JA. Ets-1 is essential for connective tissue growth factor (CTGF/ CCN2) induction by TGF-®1 in osteoblasts. PLoS One 2012; 7: e35258.
-
(2012)
PLoS One
, vol.7
-
-
Geisinger, M.T.1
Astaiza, R.2
Butler, T.3
Popoff, S.N.4
Planey, S.L.5
Arnott, J.A.6
-
67
-
-
79961010787
-
Increases in p53 expression induce ctgf synthesis by mouse and human hepatocytes and result in liver fibrosis in mice
-
Kodama T, Takehara T, Hikita H, Shimizu S, Shigekawa M, Tsunematsu H, Li W, Miyagi T, Hosui A, Tatsumi T, Ishida H, Kanto T, Hiramatsu N, Kubota S, Takigawa M, Tomimaru Y, Tomokuni A, Nagano H, Doki Y, Mori M, Hayashi N. Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice. J Clin Invest 2011; 121: 3343-56.
-
(2011)
J Clin Invest
, vol.121
, pp. 3343-3356
-
-
Kodama, T.1
Takehara, T.2
Hikita, H.3
Shimizu, S.4
Shigekawa, M.5
Tsunematsu, H.6
Li, W.7
Miyagi, T.8
Hosui, A.9
Tatsumi, T.10
Ishida, H.11
Kanto, T.12
Hiramatsu, N.13
Kubota, S.14
Takigawa, M.15
Tomimaru, Y.16
Tomokuni, A.17
Nagano, H.18
Doki, Y.19
Mori, M.20
Hayashi, N.21
more..
-
68
-
-
77951162370
-
Foxo proteins mediate hypoxic induction of connective tissue growth factor in endothelial cells
-
Samarin J, Wessel J, Cicha I, Kroening S, Warnecke C, Goppelt-Struebe M. FoxO proteins mediate hypoxic induction of connective tissue growth factor in endothelial cells. J Biol Chem 2010; 285: 4328-36.
-
(2010)
J Biol Chem
, vol.285
, pp. 4328-4336
-
-
Samarin, J.1
Wessel, J.2
Cicha, I.3
Kroening, S.4
Warnecke, C.5
Goppelt-Struebe, M.6
-
69
-
-
79953310106
-
Taxol resistance in breast cancer cells is mediated by the hippo pathway component taz and its downstream transcriptional targets cyr61 and ctgf
-
Lai D, Ho KC, Hao Y, Yang X. Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF. Cancer Res 2011; 71: 2728-38.
-
(2011)
Cancer Res
, vol.71
, pp. 2728-2738
-
-
Lai, D.1
Ho, K.C.2
Hao, Y.3
Yang, X.4
-
70
-
-
49649116469
-
Gain of oncogenic function of p53 mutants induces invasive phenotypes in human breast cancer cells by silencing ccn5/wisp-2
-
Dhar G, Banerjee S, Dhar K, Tawfik O, Mayo MS, Vanveldhuizen PJ, Banerjee SK. Gain of oncogenic function of p53 mutants induces invasive phenotypes in human breast cancer cells by silencing CCN5/WISP-2. Cancer Res 2008; 68: 4580-7.
-
(2008)
Cancer Res
, vol.68
, pp. 4580-4587
-
-
Dhar, G.1
Banerjee, S.2
Dhar, K.3
Tawfik, O.4
Mayo, M.S.5
Vanveldhuizen, P.J.6
Banerjee, S.K.7
-
71
-
-
80051791754
-
Nephroblastoma overexpressed (nov/ccn3) gene: A paired-domain-specific pax3-fkhr transcription target that promotes survival and motility in alveolar rhabdomyosarcoma cells
-
Zhang Y, Wang C. Nephroblastoma overexpressed (NOV/CCN3) gene: a paired-domain-specific PAX3-FKHR transcription target that promotes survival and motility in alveolar rhabdomyosarcoma cells. Oncogene 2011; 30: 3549-62.
-
(2011)
Oncogene
, vol.30
, pp. 3549-3562
-
-
Zhang, Y.1
Wang, C.2
-
72
-
-
0034726967
-
Identification of an rna element that confers post-Transcriptional repression of connective tissue growth factor/hypertrophic chondrocyte specific 24 (ctgf/hcs24) gene: Similarities to retroviral rna-protein interactions
-
Kubota S, Kondo S, Eguchi T, Hattori T, Nakanishi T, Pomerantz RJ, Takigawa M. Identification of an RNA element that confers post-Transcriptional repression of connective tissue growth factor/hypertrophic chondrocyte specific 24 (ctgf/hcs24) gene: similarities to retroviral RNA-protein interactions. Oncogene 2000; 19: 4773-86.
-
(2000)
Oncogene
, vol.19
, pp. 4773-4786
-
-
Kubota, S.1
Kondo, S.2
Eguchi, T.3
Hattori, T.4
Nakanishi, T.5
Pomerantz, R.J.6
Takigawa, M.7
-
73
-
-
79951580936
-
Binding of glyceraldehyde-3-phosphate dehydrogenase to the cis-Acting element of structure-Anchored repression in ccn2 mrna
-
Kondo S, Kubota S, Mukudai Y, Nishida T, Yoshihama Y, Shirota T, Shintani S, Takigawa M. Binding of glyceraldehyde-3-phosphate dehydrogenase to the cis-Acting element of structure-Anchored repression in ccn2 mRNA. Biochem Biophys Res Commun 2011; 405: 382-7.
-
(2011)
Biochem Biophys Res Commun
, vol.405
, pp. 382-387
-
-
Kondo, S.1
Kubota, S.2
Mukudai, Y.3
Nishida, T.4
Yoshihama, Y.5
Shirota, T.6
Shintani, S.7
Takigawa, M.8
-
74
-
-
0034638612
-
Characterization of a mouse ctgf 3′-utr segment that mediates repressive regulation of gene expression
-
Kondo S, Kubota S, Eguchi T, Hattori T, Nakanishi T, Sugahara T, Takigawa M. Characterization of a mouse ctgf 3′-UTR segment that mediates repressive regulation of gene expression. Biochem Biophys Res Commun 2000; 278: 119-24.
-
(2000)
Biochem Biophys Res Commun
, vol.278
, pp. 119-124
-
-
Kondo, S.1
Kubota, S.2
Eguchi, T.3
Hattori, T.4
Nakanishi, T.5
Sugahara, T.6
Takigawa, M.7
-
75
-
-
52649104020
-
Posttranscriptional regulation of chicken ccn2 gene expression by nucleophosmin/ b23 during chondrocyte differentiation
-
Mukudai Y, Kubota S, Kawaki H, Kondo S, Eguchi T, Sumiyoshi K, Ohgawara T, Shimo T, Takigawa M. Posttranscriptional regulation of chicken ccn2 gene expression by nucleophosmin/ B23 during chondrocyte differentiation. Mol Cell Biol 2008; 28: 6134-47.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6134-6147
-
-
Mukudai, Y.1
Kubota, S.2
Kawaki, H.3
Kondo, S.4
Eguchi, T.5
Sumiyoshi, K.6
Ohgawara, T.7
Shimo, T.8
Takigawa, M.9
-
76
-
-
61749098633
-
Regulation of chondrocytic phenotype by micro rna 18a: Involvement of ccn2/ctgf as a major target gene
-
Ohgawara T, Kubota S, Kawaki H, Kondo S, Eguchi T, Kurio N, Aoyama E, Sasaki A, Takigawa M. Regulation of chondrocytic phenotype by micro RNA 18a: involvement of Ccn2/Ctgf as a major target gene. FEBS Lett 2009; 583: 1006-10.
-
(2009)
FEBS Lett
, vol.583
, pp. 1006-1010
-
-
Ohgawara, T.1
Kubota, S.2
Kawaki, H.3
Kondo, S.4
Eguchi, T.5
Kurio, N.6
Aoyama, E.7
Sasaki, A.8
Takigawa, M.9
-
77
-
-
84873497493
-
Microrna-145 is downregulated in glial tumors and regulates glioma cell migration by targeting connective tissue growth factor
-
Lee HK, Bier A, Cazacu S, Finniss S, Xiang C, Twito H, Poisson LM, Mikkelsen T, Slavin S, Jacoby E, Yalon M, Toren A, Rempel SA, Brodie C. MicroRNA-145 is downregulated in glial tumors and regulates glioma cell migration by targeting connective tissue growth factor. PLoS One 2013; 8: e54652.
-
(2013)
PLoS One
, vol.8
-
-
Lee, H.K.1
Bier, A.2
Cazacu, S.3
Finniss, S.4
Xiang, C.5
Twito, H.6
Poisson, L.M.7
Mikkelsen, T.8
Slavin, S.9
Jacoby, E.10
Yalon, M.11
Toren, A.12
Rempel, S.A.13
Brodie, C.14
-
78
-
-
84880328286
-
Regulation of ccn1 via the 3′-untranslated region
-
Nakagawa Y, Minato M, Sumiyoshi K, Maeda A, Hara C, Murase Y, Nishida T, Kubota S, Takigawa M. Regulation of CCN1 via the 3′-untranslated region. J Cell Commun Signal 2013; 7: 207-17
-
(2013)
J Cell Commun Signal
, vol.7
, pp. 207-217
-
-
Nakagawa, Y.1
Minato, M.2
Sumiyoshi, K.3
Maeda, A.4
Hara, C.5
Murase, Y.6
Nishida, T.7
Kubota, S.8
Takigawa, M.9
-
79
-
-
78649772348
-
A coding rna segment that enhances the ribosomal recruitment of chicken ccn1 mrna
-
Mukudai Y, Kubota S, Eguchi T, Sumiyoshi K, Janune D, Kondo S, Shintani S, Takigawa M. A coding RNA segment that enhances the ribosomal recruitment of chicken ccn1 mRNA. J Cell Biochem 2010; 111: 1607-18.
-
(2010)
J Cell Biochem
, vol.111
, pp. 1607-1618
-
-
Mukudai, Y.1
Kubota, S.2
Eguchi, T.3
Sumiyoshi, K.4
Janune, D.5
Kondo, S.6
Shintani, S.7
Takigawa, M.8
-
80
-
-
84880324907
-
Novel role of mir-181a in cartilage metabolism
-
Sumiyoshi K, Kubota S, Ohgawara T, Kawata K, Kader TA, Nishida T, Ikeda N, Shimo T, Yamashiro T, Takigawa M. Novel role of miR-181a in cartilage metabolism. J Cell Biochem 2013; 114: 2094-100.
-
(2013)
J Cell Biochem
, vol.114
, pp. 2094-2100
-
-
Sumiyoshi, K.1
Kubota, S.2
Ohgawara, T.3
Kawata, K.4
Kader, T.A.5
Nishida, T.6
Ikeda, N.7
Shimo, T.8
Yamashiro, T.9
Takigawa, M.10
-
81
-
-
79953780809
-
Ccn5, a novel transcriptional repressor of the transforming growth factor ® signaling pathway
-
Sabbah M, Prunier C, Ferrand N, Megalophonos V, Lambein K, De Wever O, Nazaret N, Lachuer J, Dumont S, Redeuilh G. CCN5, a novel transcriptional repressor of the transforming growth factor ® signaling pathway. Mol Cell Biol 2011; 31: 1459-69.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 1459-1469
-
-
Sabbah, M.1
Prunier, C.2
Ferrand, N.3
Megalophonos, V.4
Lambein, K.5
De Wever, O.6
Nazaret, N.7
Lachuer, J.8
Dumont, S.9
Redeuilh, G.10
-
82
-
-
33846626061
-
Role of ccn2/ctgf/hcs24 in bone growth
-
Kubota S, Takigawa M. Role of CCN2/CTGF/Hcs24 in bone growth. Int Rev Cytol 2007; 257: 1-41.
-
(2007)
Int Rev Cytol
, vol.257
, pp. 1-41
-
-
Kubota, S.1
Takigawa, M.2
-
83
-
-
84880334077
-
Ccn2: A master regulator of the genesis of bone and cartilage
-
Takigawa M. CCN2: A master regulator of the genesis of bone and cartilage. J Cell Commun Signal 2013; 7: 191 -201.
-
(2013)
J Cell Commun Signal
, vol.7
, pp. 191-201
-
-
Takigawa, M.1
-
84
-
-
53149123334
-
Cooperative regulation of chondrocyte differentiation by ccn2 and ccn3 shown by a comprehensive analysis of the ccn family proteins in cartilage
-
Kawaki H, Kubota S, Suzuki A, Lazar N, Yamada T, Matsumura T, Ohgawara T, Maeda T, Perbal B, Lyons KM, Takigawa M. Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage. J Bone Miner Res 2008; 23: 1751-64.
-
(2008)
J Bone Miner Res
, vol.23
, pp. 1751-1764
-
-
Kawaki, H.1
Kubota, S.2
Suzuki, A.3
Lazar, N.4
Yamada, T.5
Matsumura, T.6
Ohgawara, T.7
Maeda, T.8
Perbal, B.9
Lyons, K.M.10
Takigawa, M.11
-
85
-
-
0038093327
-
Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development
-
Ivkovic S, Yoon BS, Popoff SN, Safadi FF, Libuda DE, Stephenson RC, Daluiski A, Lyons KM. Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development. Development 2003; 130: 2779-91.
-
(2003)
Development
, vol.130
, pp. 2779-2791
-
-
Ivkovic, S.1
Yoon, B.S.2
Popoff, S.N.3
Safadi, F.F.4
Libuda, D.E.5
Stephenson, R.C.6
Daluiski, A.7
Lyons, K.M.8
-
86
-
-
9144268023
-
Regeneration of defects in articular cartilage in rat knee joints by ccn2 (connective tissue growth factor)
-
Nishida T, Kubota S, Kojima S, Kuboki T, Nakao K, Kushibiki T, Tabata Y, Takigawa M. Regeneration of defects in articular cartilage in rat knee joints by CCN2 (connective tissue growth factor). J Bone Miner Res 2004; 19: 1308-19.
-
(2004)
J Bone Miner Res
, vol.19
, pp. 1308-1319
-
-
Nishida, T.1
Kubota, S.2
Kojima, S.3
Kuboki, T.4
Nakao, K.5
Kushibiki, T.6
Tabata, Y.7
Takigawa, M.8
-
87
-
-
45549107295
-
Promotion of bone regeneration by ccn2 incorporated into gelatin hydrogel
-
Kikuchi T, Kubota S, Asaumi K, Kawaki H, Nishida T, Kawata K, Mitani S, Tabata Y, Ozaki T, Takigawa M. Promotion of bone regeneration by CCN2 incorporated into gelatin hydrogel. Tissue Eng Part A 2008; 14: 1089-98.
-
(2008)
Tissue Eng Part A
, vol.14
, pp. 1089-1098
-
-
Kikuchi, T.1
Kubota, S.2
Asaumi, K.3
Kawaki, H.4
Nishida, T.5
Kawata, K.6
Mitani, S.7
Tabata, Y.8
Ozaki, T.9
Takigawa, M.10
-
88
-
-
80054831375
-
Differential roles of ccn family proteins during osteoblast differentiation: Involvement of smad and mapk signaling pathways
-
Kawaki H, Kubota S, Suzuki A, Suzuki M, Kohsaka K, Hoshi K, Fujii T, Lazar N, Ohgawara T, Maeda T, Perbal B, Takano-Yamamoto T, Takigawa M. Differential roles of CCN family proteins during osteoblast differentiation: involvement of Smad and MAPK signaling pathways. Bone 2011; 49: 975-9.
-
(2011)
Bone
, vol.49
, pp. 975-979
-
-
Kawaki, H.1
Kubota, S.2
Suzuki, A.3
Suzuki, M.4
Kohsaka, K.5
Hoshi, K.6
Fujii, T.7
Lazar, N.8
Ohgawara, T.9
Maeda, T.10
Perbal, B.11
Takano-Yamamoto, T.12
Takigawa, M.13
-
89
-
-
28144441980
-
New target genes for nov/ccn3 in chondrocytes: Tgf-beta2 and type x collagen
-
Lafont J, Jacques C, Le Dreau G, Calhabeu F, Thibout H, Dubois C, Berenbaum F, Laurent M, Martinerie C. New target genes for NOV/CCN3 in chondrocytes: TGF-beta2 and type X collagen. J Bone Miner Res 2005; 20: 2213-23.
-
(2005)
J Bone Miner Res
, vol.20
, pp. 2213-2223
-
-
Lafont, J.1
Jacques, C.2
Le Dreau, G.3
Calhabeu, F.4
Thibout, H.5
Dubois, C.6
Berenbaum, F.7
Laurent, M.8
Martinerie, C.9
-
90
-
-
84880050509
-
Ccn3 participates in bone regeneration as an inhibitory factor
-
Matsushita Y, Sakamoto K, Tamamura Y, Shibata Y, Minamizato T, Kihara T, Ito M, Katsube KI, Hiraoka S, Koseki H, Harada K, Yamaguchi A. CCN3 participates in bone regeneration as an inhibitory factor. J Biol Chem 2013; 288: 19973-85.
-
(2013)
J Biol Chem
, vol.288
, pp. 19973-19985
-
-
Matsushita, Y.1
Sakamoto, K.2
Tamamura, Y.3
Shibata, Y.4
Minamizato, T.5
Kihara, T.6
Ito, M.7
Katsube, K.I.8
Hiraoka, S.9
Koseki, H.10
Harada, K.11
Yamaguchi, A.12
-
91
-
-
80053236874
-
Novel effects of ccn3 that may direct the differentiation of chondrocytes
-
Janune D, Kubota S, Nishida T, Kawaki H, Perbal B, Iida S, Takigawa M. Novel effects of CCN3 that may direct the differentiation of chondrocytes. FEBS Lett 2011; 885: 3033-40.
-
(2011)
FEBS Lett
, vol.885
, pp. 3033-3040
-
-
Janune, D.1
Kubota, S.2
Nishida, T.3
Kawaki, H.4
Perbal, B.5
Iida, S.6
Takigawa, M.7
-
92
-
-
43149111611
-
Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the nov (ccn3) gene
-
Heath E, Tahri D, Andermarcher E, Schofield P, Fleming S, Boulter CA. Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) gene. Dev Biol 2008; 8: 18.
-
(2008)
Dev Biol
, vol.8
, pp. 18
-
-
Heath, E.1
Tahri, D.2
Andermarcher, E.3
Schofield, P.4
Fleming, S.5
Boulter, C.A.6
-
93
-
-
84862021148
-
Novel and recurrent mutations of wisp3 in two chinese families with progressive pseudorheumatoid dysplasia
-
Sun J, Xia W, He S, Zhao Z, Nie M, Li M, Jiang Y, Xing X, Wang O, Meng X, Zhou X. Novel and recurrent mutations of WISP3 in two Chinese families with progressive pseudorheumatoid dysplasia. PLoS One 2012; 7: e38643.
-
(2012)
PLoS One
, vol.7
-
-
Sun, J.1
Xia, W.2
He, S.3
Zhao, Z.4
Nie, M.5
Li, M.6
Jiang, Y.7
Xing, X.8
Wang, O.9
Meng, X.10
Zhou, X.11
-
94
-
-
84855825971
-
Molecular differentiation between osteophytic and articular cartilage-clues for a transient and permanent chondrocyte phenotype
-
Gelse K, Ekici AB, Cipa F, Swoboda B, Carl HD, Olk A, Hennig FF, Klinger P. Molecular differentiation between osteophytic and articular cartilage -clues for a transient and permanent chondrocyte phenotype. Osteoarthritis Cartilage 2012; 20: 162-71.
-
(2012)
Osteoarthritis Cartilage
, vol.20
, pp. 162-171
-
-
Gelse, K.1
Ekici, A.B.2
Cipa, F.3
Swoboda, B.4
Carl, H.D.5
Olk, A.6
Hennig, F.F.7
Klinger, P.8
-
95
-
-
35649008827
-
Wisp3 suppresses insulin-like growth factor signaling in human chondrocytes
-
Cui RR, Huang J, Yi L, Xie H, Zhou HD, Yuan LQ, Wang M, Peng YQ, Luo XH, Liao EY. WISP3 suppresses insulin-like growth factor signaling in human chondrocytes. Mol Cell Endocrinol 2007; 279: 1-8.
-
(2007)
Mol Cell Endocrinol
, vol.279
, pp. 1-8
-
-
Cui, R.R.1
Huang, J.2
Yi, L.3
Xie, H.4
Zhou, H.D.5
Yuan, L.Q.6
Wang, M.7
Peng, Y.Q.8
Luo, X.H.9
Liao, E.Y.10
-
96
-
-
33750480252
-
The matricellular protein ccn1 is essential for cardiac development
-
Mo FE, Lau LF. The matricellular protein CCN1 is essential for cardiac development. Circ Res 2006; 99: 961-9.
-
(2006)
Circ Res
, vol.99
, pp. 961-969
-
-
Mo, F.E.1
Lau, L.F.2
-
97
-
-
0036892032
-
Cyr61 (ccn1) is essential for placental development and vascular integrity
-
Mo FE, Muntean AG, Chen CC, Stolz DB, Watkins SC, Lau LF. CYR61 (CCN1) is essential for placental development and vascular integrity. Mol Cell Biol 2002; 22: 8709-20.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 8709-8720
-
-
Mo, F.E.1
Muntean, A.G.2
Chen, C.C.3
Stolz, D.B.4
Watkins, S.C.5
Lau, L.F.6
-
98
-
-
33244456090
-
Hypoxic regulation of stability of connective tissue growth factor/ccn2 mrna by 3′-untranslated region interacting with a cellular protein in human chondrosarcoma cells
-
Kondo S, Kubota S, Mukudai Y, Moritani N, Nishida T, Matsushita H, Matsumoto S, Sugahara T, Takigawa M. Hypoxic regulation of stability of connective tissue growth factor/CCN2 mRNA by 3′-untranslated region interacting with a cellular protein in human chondrosarcoma cells. Oncogene 2006; 25: 1099-110.
-
(2006)
Oncogene
, vol.25
, pp. 1099-1110
-
-
Kondo, S.1
Kubota, S.2
Mukudai, Y.3
Moritani, N.4
Nishida, T.5
Matsushita, H.6
Matsumoto, S.7
Sugahara, T.8
Takigawa, M.9
-
99
-
-
33745497854
-
Pathogenic role of connective tissue growth factor (ctgf/ccn2) in osteolytic metastasis of breast cancer
-
Shimo T, Kubota S, Yoshioka N, Ibaragi S, Isowa S, Eguchi T, Sasaki A, Takigawa M. Pathogenic role of connective tissue growth factor (CTGF/CCN2) in osteolytic metastasis of breast cancer. J Bone Miner Res 2006; 21: 1045-59.
-
(2006)
J Bone Miner Res
, vol.21
, pp. 1045-1059
-
-
Shimo, T.1
Kubota, S.2
Yoshioka, N.3
Ibaragi, S.4
Isowa, S.5
Eguchi, T.6
Sasaki, A.7
Takigawa, M.8
-
100
-
-
79956105716
-
Ccn6 (wisp3) decreases zeb1-mediated emt and invasion by attenuation of igf-1 receptor signaling in breast cancer
-
Lorenzatti G, Huang W, Pal A, Cabanillas AM, Kleer CG. CCN6 (WISP3) decreases ZEB1-mediated EMT and invasion by attenuation of IGF-1 receptor signaling in breast cancer. J Cell Sci 2011; 124: 1752-8.
-
(2011)
J Cell Sci
, vol.124
, pp. 1752-1758
-
-
Lorenzatti, G.1
Huang, W.2
Pal, A.3
Cabanillas, A.M.4
Kleer, C.G.5
-
101
-
-
84863085243
-
On how ccn6 suppresses breast cancer growth and invasion
-
Huang W, Pal A, Kleer CG. On how CCN6 suppresses breast cancer growth and invasion. J Cell Commun Signal 2012; 6: 5-10.
-
(2012)
J Cell Commun Signal
, vol.6
, pp. 5-10
-
-
Huang, W.1
Pal, A.2
Kleer, C.G.3
-
102
-
-
77950868711
-
Ccn3 inhibits neointimal hyperplasia through modulation of smooth muscle cell growth and migration
-
Shimoyama T, Hiraoka S, Takemoto M, Koshizaka M, Tokuyama H, Tokuyama T, Watanabe A, Fujimoto M, Kawamura H, Sato S, Tsurutani Y, Saito Y, Perbal B, Koseki H, Yokote K. CCN3 inhibits neointimal hyperplasia through modulation of smooth muscle cell growth and migration. Arterioscler Thromb Vasc Biol 2010; 30: 675-82.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 675-682
-
-
Shimoyama, T.1
Hiraoka, S.2
Takemoto, M.3
Koshizaka, M.4
Tokuyama, H.5
Tokuyama, T.6
Watanabe, A.7
Fujimoto, M.8
Kawamura, H.9
Sato, S.10
Tsurutani, Y.11
Saito, Y.12
Perbal, B.13
Koseki, H.14
Yokote, K.15
-
103
-
-
41449097556
-
Plasma connective tissue growth factor is a novel potential biomarker of cardiac dysfunction in patients with chronic heart failure
-
Koitabashi N, Arai M, Niwano K, Watanabe A, Endoh M, Suguta M, Yokoyama T, Tada H, Toyama T, Adachi H, Naito S, Oshima S, Nishida T, Kubota S, Takigawa M, Kurabayashi M. Plasma connective tissue growth factor is a novel potential biomarker of cardiac dysfunction in patients with chronic heart failure. Eur J Heart Fail 2008; 10: 373-9.
-
(2008)
Eur J Heart Fail
, vol.10
, pp. 373-379
-
-
Koitabashi, N.1
Arai, M.2
Niwano, K.3
Watanabe, A.4
Endoh, M.5
Suguta, M.6
Yokoyama, T.7
Tada, H.8
Toyama, T.9
Adachi, H.10
Naito, S.11
Oshima, S.12
Nishida, T.13
Kubota, S.14
Takigawa, M.15
Kurabayashi, M.16
-
104
-
-
34548413245
-
Wnt-induced secreted protein-1 is a prohypertrophic and profibrotic growth factor
-
Colston JT, de la Rosa SD, Koehler M, Gonzales K, Mestril R, Freeman GL, Bailey SR, Chandrasekar B. Wnt-induced secreted protein-1 is a prohypertrophic and profibrotic growth factor. Am J Physiol Heart Circ Physiol 2007; 293: H1839-46.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
-
-
Colston, J.T.1
De La Rosa, S.D.2
Koehler, M.3
Gonzales, K.4
Mestril, R.5
Freeman, G.L.6
Bailey, S.R.7
Chandrasekar, B.8
-
105
-
-
84888620186
-
Ccn2/ctgf attenuates myocardial hypertrophy and cardiac dysfunction upon chronic pressure-overload. Int j cardiol. 2013. In press. 106. Sumiyoshi k, kubota s, furuta ra, yasui k, aoyama e, kawaki h, kawata k, ohgawara t, yamashiro t, takigawa m. Thrombopoietic-mesenchymal interaction that may facilitate both endochondral ossification and platelet maturation via ccn2
-
Gravning J, Ahmed MS, von Lueder TG, Edvardsen T, Attramadal H. CCN2/CTGF attenuates myocardial hypertrophy and cardiac dysfunction upon chronic pressure-overload. Int J Cardiol. 2013. in press. 106. Sumiyoshi K, Kubota S, Furuta RA, Yasui K, Aoyama E, Kawaki H, Kawata K, Ohgawara T, Yamashiro T, Takigawa M. Thrombopoietic-mesenchymal interaction that may facilitate both endochondral ossification and platelet maturation via CCN2. J Cell Commun Signal 2010; 4: 5-14.
-
(2010)
J Cell Commun Signal
, vol.4
, pp. 5-14
-
-
Gravning, J.1
Ahmed, M.S.2
Von Lueder, T.G.3
Edvardsen, T.4
Attramadal, H.5
-
106
-
-
34247623492
-
Nov (ccn3) functions as a regulator of human hematopoietic stem or progenitor cells
-
Gupta R, Hong D, Iborra F, Sarno S, Enver T. NOV (CCN3) functions as a regulator of human hematopoietic stem or progenitor cells. Science 2007; 316: 590-3.
-
(2007)
Science
, vol.316
, pp. 590-593
-
-
Gupta, R.1
Hong, D.2
Iborra, F.3
Sarno, S.4
Enver, T.5
-
107
-
-
60849137834
-
Ccn3 -A key regulator of the hematopoietic compartment
-
McCallum L, Irvine AE. CCN3 -A key regulator of the hematopoietic compartment. Blood Rev 2009; 23: 79-85.
-
(2009)
Blood Rev
, vol.23
, pp. 79-85
-
-
McCallum, L.1
Irvine, A.E.2
-
108
-
-
0033542768
-
Immunohistochemical localization of connective tissue growth factor in the rat central nervous system
-
Kondo Y, Nakanishi T, Takigawa M, Ogawa N. Immunohistochemical localization of connective tissue growth factor in the rat central nervous system. Brain Res 1999; 834: 146-51.
-
(1999)
Brain Res
, vol.834
, pp. 146-151
-
-
Kondo, Y.1
Nakanishi, T.2
Takigawa, M.3
Ogawa, N.4
-
109
-
-
18644362231
-
Tyrosine kinase-Type receptor erbb4 in chondrocytes: Interaction with connective tissue growth factor and distribution in cartilage
-
Nawachi K, Inoue M, Kubota S, Nishida T, Yosimichi G, Nakanishi T, Kanyama M, Kuboki T, Yatani H, Yamaai T, Takigawa M. Tyrosine kinase-Type receptor ErbB4 in chondrocytes: interaction with connective tissue growth factor and distribution in cartilage. FEBS Lett 2002; 528: 109-13.
-
(2002)
FEBS Lett
, vol.528
, pp. 109-113
-
-
Nawachi, K.1
Inoue, M.2
Kubota, S.3
Nishida, T.4
Yosimichi, G.5
Nakanishi, T.6
Kanyama, M.7
Kuboki, T.8
Yatani, H.9
Yamaai, T.10
Takigawa, M.11
-
110
-
-
84875471193
-
Cyr61, a matricellular protein, is needed for dendritic arborization of hippocampal neurons
-
Malik AR, Urbanska M, Gozdz A, Swiech LJ, Nagalski A, Perycz M, Blazejczyk M, Jaworski J. Cyr61, a matricellular protein, is needed for dendritic arborization of hippocampal neurons. J Biol Chem 2013; 288: 8544-59.
-
(2013)
J Biol Chem
, vol.288
, pp. 8544-8559
-
-
Malik, A.R.1
Urbanska, M.2
Gozdz, A.3
Swiech, L.J.4
Nagalski, A.5
Perycz, M.6
Blazejczyk, M.7
Jaworski, J.8
-
111
-
-
28744437870
-
Connective tissue growth factor (ctgf) expression in the brain is a downstream effector of insulin resistance-Associated promotion of alzheimer's disease beta-Amyloid neuropathology
-
Zhao Z, Ho L, Wang J, Qin W, Festa ED, Mobbs C, Hof P, Rocher A, Masur S, Haroutunian V, Pasinetti GM. Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance-Associated promotion of Alzheimer's disease beta-Amyloid neuropathology. FASEB J 2005; 19: 2081-2.
-
(2005)
FASEB J
, vol.19
, pp. 2081-2082
-
-
Zhao, Z.1
Ho, L.2
Wang, J.3
Qin, W.4
Festa, E.D.5
Mobbs, C.6
Hof, P.7
Rocher, A.8
Masur, S.9
Haroutunian, V.10
Pasinetti, G.M.11
-
112
-
-
72149128454
-
Nov/ccn3 promotes maturation of cerebellar granule neuron precursors
-
Le Dréau G, Nicot A, Bénard M, Thibout H, Vaudry D, Martinerie C, Laurent M. NOV/CCN3 promotes maturation of cerebellar granule neuron precursors. Mol Cell Neurosci 2010; 43: 60-71.
-
(2010)
Mol Cell Neurosci
, vol.43
, pp. 60-471
-
-
Le Dréau, G.1
Nicot, A.2
Bénard, M.3
Thibout, H.4
Vaudry, D.5
Martinerie, C.6
Laurent, M.7
-
113
-
-
84873052754
-
Tuberous sclerosis protein 2 (tsc2) modulates ccn4 cytoprotection during apoptotic amyloid toxicity in microglia
-
Shang YC, Chong ZZ, Wang S, Maiese K. Tuberous sclerosis protein 2 (TSC2) modulates CCN4 cytoprotection during apoptotic amyloid toxicity in microglia. Curr Neurovasc Res 2013; 10: 29-38.
-
(2013)
Curr Neurovasc Res
, vol.10
, pp. 29-138
-
-
Shang, Y.C.1
Chong, Z.Z.2
Wang, S.3
Maiese, K.4
-
114
-
-
84874256781
-
Regulation of pancreatic function by connective tissue growth factor (ctgf, ccn2)
-
Charrier A, Brigstock DR. Regulation of pancreatic function by connective tissue growth factor (CTGF, CCN2). Cytokine Growth Factor Rev 2013; 24: 59-68.
-
(2013)
Cytokine Growth Factor Rev
, vol.24
, pp. 59-268
-
-
Charrier, A.1
Brigstock, D.R.2
-
115
-
-
84891371068
-
Cysteine-rich protein 61 (ccn1) and connective tissue growth factor (ccn2) at the crosshairs of ocular neovascular and fibrovascular disease therapy
-
Yan L, Chaqour B. Cysteine-rich protein 61 (CCN1) and connective tissue growth factor (CCN2) at the crosshairs of ocular neovascular and fibrovascular disease therapy. J Cell Commun Signal 2013. in press.
-
J Cell Commun Signal 2013. in press
-
-
Yan, L.1
Chaqour, B.2
-
116
-
-
84867410774
-
Temporal and spatial expression of ccn3 during retina development
-
Maryvonne L, Gwenvaël le D, Xavier G, Cécile LE, Amélie S, Olivier G, Cécile M, Maria M. Temporal and spatial expression of CCN3 during retina development. Dev Neurobiol 2012; 72: 1363-75.
-
(2012)
Dev Neurobiol
, vol.72
, pp. 1363-1375
-
-
Maryvonne, L.1
Gwenvaël Le, D.2
Xavier, G.3
Cécile, L.E.4
Amélie, S.5
Olivier, G.6
Cécile, M.7
Maria, M.8
-
117
-
-
84864307725
-
Ccn2 in orofacial development and remodeling
-
Kubota S. CCN2 in orofacial development and remodeling. Jpn Dent Sci Rev 2012; 48: 101-13.
-
(2012)
Jpn Dent Sci Rev
, vol.48
, pp. 101-113
-
-
Kubota, S.1
-
118
-
-
84874935003
-
Anti-fibrotic effect of ccn3 accompanied by altered gene expression profile of the ccn family
-
Abd El Kader T, Kubota S, Janune D, Nishida T, Hattori T, Aoyama E, Perbal B, Kuboki T, Takigawa M. Anti-fibrotic effect of CCN3 accompanied by altered gene expression profile of the CCN family. J Cell Commun Signal 2013; 7: 11-8.
-
(2013)
J Cell Commun Signal
, vol.7
, pp. 11-18
-
-
Abd El Kader, T.1
Kubota, S.2
Janune, D.3
Nishida, T.4
Hattori, T.5
Aoyama, E.6
Perbal, B.7
Kuboki, T.8
Takigawa, M.9
-
119
-
-
77954243065
-
The matricellular protein ccn1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing
-
Jun JI, Lau LF. The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing. Nat Cell Biol 2010; 12: 676-85.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 676-685
-
-
Jun, J.I.1
Lau, L.F.2
-
120
-
-
35348876638
-
Expression of ccn1 (cyr61) in developing, normal, and diseased human kidney
-
Sawai K, Mukoyama M, Mori K, Kasahara M, Koshikawa M, Yokoi H, Yoshioka T, Ogawa Y, Sugawara A, Nishiyama H, Yamada S, Kuwahara T, Saleem MA, Shiota K, Ogawa O, Miyazato M, Kangawa K, Nakao K. Expression of CCN1 (CYR61) in developing, normal, and diseased human kidney. Am J Physiol Renal Physiol 2007; 293: F1363-72.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
-
-
Sawai, K.1
Mukoyama, M.2
Mori, K.3
Kasahara, M.4
Koshikawa, M.5
Yokoi, H.6
Yoshioka, T.7
Ogawa, Y.8
Sugawara, A.9
Nishiyama, H.10
Yamada, S.11
Kuwahara, T.12
Saleem, M.A.13
Shiota, K.14
Ogawa, O.15
Miyazato, M.16
Kangawa, K.17
Nakao, K.18
-
121
-
-
70849136597
-
Connective tissue growth factor-(ctgf ccn2)-A marker, mediator and therapeutic target for renal fibrosis
-
Phanish MK, Winn SK, Dockrell ME. Connective tissue growth factor-(CTGF, CCN2) -A marker, mediator and therapeutic target for renal fibrosis. Nephron Exp Nephrol 2010; 114: e83-92.
-
(2010)
Nephron Exp Nephrol
, vol.114
-
-
Phanish, M.K.1
Winn, S.K.2
Dockrell, M.E.3
-
122
-
-
79953215255
-
The matricellular protein cysteine-rich protein 61 (ccn1/cyr61) enhances physiological adaptation of retinal vessels and reduces pathological neovascularization associated with ischemic retinopathy
-
Hasan A, Pokeza N, Shaw L, Lee HS, Lazzaro D, Chintala H, Rosenbaum D, Grant MB, Chaqour B. The matricellular protein cysteine-rich protein 61 (CCN1/Cyr61) enhances physiological adaptation of retinal vessels and reduces pathological neovascularization associated with ischemic retinopathy. J Biol Chem 2011; 286: 9542-54.
-
(2011)
J Biol Chem
, vol.286
, pp. 9542-9554
-
-
Hasan, A.1
Pokeza, N.2
Shaw, L.3
Lee, H.S.4
Lazzaro, D.5
Chintala, H.6
Rosenbaum, D.7
Grant, M.B.8
Chaqour, B.9
-
123
-
-
65649136944
-
Ccn3 (nov) is a negative regulator of ccn2 (ctgf) and a novel endogenous inhibitor of the fibrotic pathway in an in vitro model of renal disease
-
Riser BL, Najmabadi F, Perbal B, Peterson DR, Rambow JA, Riser ML, Sukowski E, Yeger H, Riser SC. CCN3 (NOV) is a negative regulator of CCN2 (CTGF) and a novel endogenous inhibitor of the fibrotic pathway in an in vitro model of renal disease. Am J Pathol 2009; 174: 1725-34.
-
(2009)
Am J Pathol
, vol.174
, pp. 1725-1734
-
-
Riser, B.L.1
Najmabadi, F.2
Perbal, B.3
Peterson, D.R.4
Rambow, J.A.5
Riser, M.L.6
Sukowski, E.7
Yeger, H.8
Riser, S.C.9
-
124
-
-
65249088418
-
Wnt1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis
-
Königshoff M, Kramer M, Balsara N, Wilhelm J, Amarie OV, Jahn A, Rose F, Fink L, Seeger W, Schaefer L, Günther A, Eickelberg O. WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis. J Clin Invest 2009; 119: 772-87.
-
(2009)
J Clin Invest
, vol.119
, pp. 772-787
-
-
Königshoff, M.1
Kramer, M.2
Balsara, N.3
Wilhelm, J.4
Amarie, O.V.5
Jahn, A.6
Rose, F.7
Fink, L.8
Seeger, W.9
Schaefer, L.10
Günther, A.11
Eickelberg, O.12
-
125
-
-
80052809211
-
Ccn6 as a profibrotic mediator that stimulates the proliferation of lung fibroblasts via the integrin ®1/focal adhesion kinase pathway
-
Batmunkh R, Nishioka Y, Aono Y, Azuma M, Kinoshita K, Kishi J, Makino H, Kishi M, Takezaki A, Sone S. CCN6 as a profibrotic mediator that stimulates the proliferation of lung fibroblasts via the integrin ®1/focal adhesion kinase pathway. J Med Invest 2011; 58: 188-96.
-
(2011)
J Med Invest
, vol.58
, pp. 188-196
-
-
Batmunkh, R.1
Nishioka, Y.2
Aono, Y.3
Azuma, M.4
Kinoshita, K.5
Kishi, J.6
Makino, H.7
Kishi, M.8
Takezaki, A.9
Sone, S.10
-
126
-
-
84878975251
-
Matricellular protein ccn1 promotes regression of liver fibrosis through induction of cellular senescence in hepatic myofibroblasts
-
Kim KH, Chen CC, Monzon RI, Lau LF. Matricellular protein CCN1 promotes regression of liver fibrosis through induction of cellular senescence in hepatic myofibroblasts. Mol Cell Biol 2013; 33: 2078-90.
-
(2013)
Mol Cell Biol
, vol.33
, pp. 2078-2090
-
-
Kim, K.H.1
Chen, C.C.2
Monzon, R.I.3
Lau, L.F.4
-
127
-
-
81355149683
-
Ctgf/ccn-2 over-expression can directly induce features of skeletal muscle dystrophy
-
Morales MG, Cabello-Verrugio C, Santander C, Cabrera D, Goldschmeding R, Brandan E. CTGF/CCN-2 over-expression can directly induce features of skeletal muscle dystrophy. J Pathol 2011; 225: 490-501.
-
(2011)
J Pathol
, vol.225
, pp. 490-4501
-
-
Morales, M.G.1
Cabello-Verrugio, C.2
Santander, C.3
Cabrera, D.4
Goldschmeding, R.5
Brandan, E.6
-
128
-
-
84874549076
-
Ctgf induces monocyte chemoattractant protein-1 expression to enhance monocyte migration in human synovial fibroblasts
-
Liu SC, Hsu CJ, Fong YC, Chuang SM, Tang CH. CTGF induces monocyte chemoattractant protein-1 expression to enhance monocyte migration in human synovial fibroblasts. Biochim Biophys Acta 2013; 1833: 1114-24.
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 1114-1124
-
-
Liu, S.C.1
Hsu, C.J.2
Fong, Y.C.3
Chuang, S.M.4
Tang, C.H.5
-
129
-
-
60149091505
-
Cyr61 increases migration and mmp-13 expression via 〈v®3 integrin, fak, erk and ap-1-dependent pathway in human chondrosarcoma cells
-
Tan TW, Yang WH, Lin YT, Hsu SF, Li TM, Kao ST, Chen WC, Fong YC, Tang CH. Cyr61 increases migration and MMP-13 expression via 〈v®3 integrin, FAK, ERK and AP-1-dependent pathway in human chondrosarcoma cells. Carcinogenesis 2009; 30: 258-68.
-
(2009)
Carcinogenesis
, vol.30
, pp. 258-268
-
-
Tan, T.W.1
Yang, W.H.2
Lin, Y.T.3
Hsu, S.F.4
Li, T.M.5
Kao, S.T.6
Chen, W.C.7
Fong, Y.C.8
Tang, C.H.9
-
130
-
-
0036262188
-
Connective tissue growth factor increased by hypoxia may initiate angiogenesis in collaboration with matrix metalloproteinases
-
Kondo S, Kubota S, Shimo T, Nishida T, Yosimichi G, Eguchi T, Sugahara T, Takigawa M. Connective tissue growth factor increased by hypoxia may initiate angiogenesis in collaboration with matrix metalloproteinases. Carcinogenesis 2002; 23: 769-76.
-
(2002)
Carcinogenesis
, vol.23
, pp. 769-776
-
-
Kondo, S.1
Kubota, S.2
Shimo, T.3
Nishida, T.4
Yosimichi, G.5
Eguchi, T.6
Sugahara, T.7
Takigawa, M.8
-
131
-
-
80053135249
-
Ccn3 increases cell motility and mmp-13 expression in human chondrosarcoma through integrindependent pathway
-
Tzeng HE, Chen JC, Tsai CH, Kuo CC, Hsu HC, Hwang WL, Fong YC, Tang CH. CCN3 increases cell motility and MMP-13 expression in human chondrosarcoma through integrindependent pathway. J Cell Physiol 2011; 226: 3181-9.
-
(2011)
J Cell Physiol
, vol.226
, pp. 3181-3189
-
-
Tzeng, H.E.1
Chen, J.C.2
Tsai, C.H.3
Kuo, C.C.4
Hsu, H.C.5
Hwang, W.L.6
Fong, Y.C.7
Tang, C.H.8
-
132
-
-
0038175548
-
Overexpression of wisp-1 down-regulated motility and invasion of lung cancer cells through inhibition of rac activation
-
Soon LL, Yie TA, Shvarts A, Levine AJ, Su F, Tchou-Wong KM. Overexpression of WISP-1 down-regulated motility and invasion of lung cancer cells through inhibition of Rac activation. J Biol Chem 2003; 278: 11465-70.
-
(2003)
J Biol Chem
, vol.278
, pp. 11465-11470
-
-
Soon, L.L.1
Yie, T.A.2
Shvarts, A.3
Levine, A.J.4
Su, F.5
Tchou-Wong, K.M.6
-
133
-
-
54749145426
-
Ccn5/wisp-2 expression in breast adenocarcinoma is associated with less frequent progression of the disease and suppresses the invasive phenotypes of tumor cells
-
Banerjee S, Dhar G, Haque I, Kambhampati S, Mehta S, Sengupta K, Tawfik O, Phillips TA, Banerjee SK. CCN5/WISP-2 expression in breast adenocarcinoma is associated with less frequent progression of the disease and suppresses the invasive phenotypes of tumor cells. Cancer Res 2008; 68: 7606-12.
-
(2008)
Cancer Res
, vol.68
, pp. 7606-7612
-
-
Banerjee, S.1
Dhar, G.2
Haque, I.3
Kambhampati, S.4
Mehta, S.5
Sengupta, K.6
Tawfik, O.7
Phillips, T.A.8
Banerjee, S.K.9
-
134
-
-
0037474701
-
Suppressive effect of overexpressed connective tissue growth factor on tumor cell growth in a human oral squamous cell carcinoma-derived cell line
-
Moritani NH, Kubota S, Nishida T, Kawaki H, Kondo S, Sugahara T, Takigawa M. Suppressive effect of overexpressed connective tissue growth factor on tumor cell growth in a human oral squamous cell carcinoma-derived cell line. Cancer Lett 2003; 192: 205-14.
-
(2003)
Cancer Lett
, vol.192
, pp. 205-214
-
-
Moritani, N.H.1
Kubota, S.2
Nishida, T.3
Kawaki, H.4
Kondo, S.5
Sugahara, T.6
Takigawa, M.7
-
135
-
-
84880301279
-
Ccn3 promotes prostate cancer bone metastasis by modulating the tumor-bone microenvironment through rankl-dependent pathway
-
Chen PC, Cheng HC, Tang CH. CCN3 promotes prostate cancer bone metastasis by modulating the tumor-bone microenvironment through RANKL-dependent pathway. Carcinogenesis 2013; 34: 1669-79.
-
(2013)
Carcinogenesis
, vol.34
, pp. 1669-1679
-
-
Chen, P.C.1
Cheng, H.C.2
Tang, C.H.3
-
136
-
-
11244333091
-
Differential expression of the ccn family members cyr61, ctgf and nov in human breast cancer
-
Jiang WG, Watkins G, Fodstad O, Douglas-Jones A, Mokbel K, Mansel RE. Differential expression of the CCN family members Cyr61, CTGF and Nov in human breast cancer. Endocr Relat Cancer 2004; 11: 781-91.
-
(2004)
Endocr Relat Cancer
, vol.11
, pp. 781-791
-
-
Jiang, W.G.1
Watkins, G.2
Fodstad, O.3
Douglas-Jones, A.4
Mokbel, K.5
Mansel, R.E.6
-
137
-
-
79959244877
-
Ccn3 impairs osteoblast and stimulates osteoclast differentiation to favor breast cancer metastasis to bone
-
Ouellet V, Tiedemann K, Mourskaia A, Fong JE, Tran-Thanh D, Amir E, Clemons M, Perbal B, Komarova SV, Siegel PM. CCN3 impairs osteoblast and stimulates osteoclast differentiation to favor breast cancer metastasis to bone. Am J Pathol 2011; 178: 2377-88.
-
(2011)
Am J Pathol
, vol.178
, pp. 2377-2388
-
-
Ouellet, V.1
Tiedemann, K.2
Mourskaia, A.3
Fong, J.E.4
Tran-Thanh, D.5
Amir, E.6
Clemons, M.7
Perbal, B.8
Komarova, S.V.9
Siegel, P.M.10
-
138
-
-
84870044156
-
Connective tissue growth factor regulates retinal neovascularization through p53 proteindependent transactivation of the matrix metalloproteinase (mmp)-2 gene
-
Chintala H, Liu H, Parmar R, Kamalska M, Kim YJ, Lovett D, Grant MB, Chaqour B. Connective tissue growth factor regulates retinal neovascularization through p53 proteindependent transactivation of the matrix metalloproteinase (MMP)-2 gene. J Biol Chem 2012; 287: 40570-85.
-
(2012)
J Biol Chem
, vol.287
, pp. 40570-40585
-
-
Chintala, H.1
Liu, H.2
Parmar, R.3
Kamalska, M.4
Kim, Y.J.5
Lovett, D.6
Grant, M.B.7
Chaqour, B.8
-
139
-
-
0036481769
-
Connective tissue growth factor binds vascular endothelial growth factor (vegf) and inhibits vegf-induced angiogenesis
-
Inoki I, Shiomi T, Hashimoto G, Enomoto H, Nakamura H, Makino K, Ikeda E, Takata S, Kobayashi K, Okada Y. Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis. FASEB J 2002; 16: 219-21.
-
(2002)
FASEB J
, vol.16
, pp. 219-221
-
-
Inoki, I.1
Shiomi, T.2
Hashimoto, G.3
Enomoto, H.4
Nakamura, H.5
Makino, K.6
Ikeda, E.7
Takata, S.8
Kobayashi, K.9
Okada, Y.10
-
140
-
-
84874929596
-
Vitreous timp-1 levels associate with neovascularization and tgf-®2 levels but not with fibrosis in the clinical course of proliferative diabetic retinopathy
-
Van Geest RJ, Klaassen I, Lesnik-Oberstein SY, Tan HS, Mura M, Goldschmeding R, Van Noorden CJ, Schlingemann RO. Vitreous TIMP-1 levels associate with neovascularization and TGF-®2 levels but not with fibrosis in the clinical course of proliferative diabetic retinopathy. J Cell Commun Signal 2013; 7: 1-9.
-
(2013)
J Cell Commun Signal
, vol.7
, pp. 1-9
-
-
Van Geest, R.J.1
Klaassen, I.2
Lesnik-Oberstein, S.Y.3
Tan, H.S.4
Mura, M.5
Goldschmeding, R.6
Van Noorden, C.J.7
Schlingemann, R.O.8
-
141
-
-
1442348817
-
Accumulation of nh2-Terminal fragment of connective tissue growth factor in the vitreous of patients with proliferative diabetic retinopathy
-
Hinton DR, Spee C, He S, Weitz S, Usinger W, LaBree L, Oliver N, Lim JI. Accumulation of NH2-Terminal fragment of connective tissue growth factor in the vitreous of patients with proliferative diabetic retinopathy. Diabetes Care 2004; 27: 758-64.
-
(2004)
Diabetes Care
, vol.27
, pp. 758-764
-
-
Hinton, D.R.1
Spee, C.2
He, S.3
Weitz, S.4
Usinger, W.5
LaBree, L.6
Oliver, N.7
Lim, J.I.8
-
142
-
-
84861584720
-
Connective tissue growth factor causes glaucoma by modifying the actin cytoskeleton of the trabecular meshwork
-
Junglas B, Kuespert S, Seleem AA, Struller T, Ullmann S, Bösl M, Bosserhoff A, Köstler J, Wagner R, Tamm ER, Fuchshofer R. Connective tissue growth factor causes glaucoma by modifying the actin cytoskeleton of the trabecular meshwork. Am J Pathol 2012; 180: 2386-2403.
-
(2012)
Am J Pathol
, vol.180
, pp. 2386-2403
-
-
Junglas, B.1
Kuespert, S.2
Seleem, A.A.3
Struller, T.4
Ullmann, S.5
Bösl, M.6
Bosserhoff, A.7
Köstler, J.8
Wagner, R.9
Tamm, E.R.10
Fuchshofer, R.11
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