-
2
-
-
67049145082
-
Regulatory role of CCN3 in melanoma cell interaction with the extracellular matrix
-
Vallacchi V, Rodolfo M. Regulatory role of CCN3 in melanoma cell interaction with the extracellular matrix. Cell Adh Migr 2009;3:7-10.
-
(2009)
Cell Adh Migr
, vol.3
, pp. 7-10
-
-
Vallacchi, V.1
Rodolfo, M.2
-
3
-
-
53149092430
-
The CCN family of proteins: Structure-function relationships
-
Holbourn KP, Acharya KR, Perbal B. The CCN family of proteins: structure-function relationships. Trends Biochem Sci 2008;33:461-73.
-
(2008)
Trends Biochem Sci
, vol.33
, pp. 461-473
-
-
Holbourn, K.P.1
Acharya, K.R.2
Perbal, B.3
-
4
-
-
82455198983
-
Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets
-
Jun JI, Lau LF. Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets. Nat Rev Drug Discov 2011;10:945-63.
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 945-963
-
-
Jun, J.I.1
Lau, L.F.2
-
5
-
-
37549015508
-
The CCN3 protein and cancer
-
Perbal B. The CCN3 protein and cancer. Adv Exp Med Biol 2006;587:23-40.
-
(2006)
Adv Exp Med Biol
, vol.587
, pp. 23-40
-
-
Perbal, B.1
-
7
-
-
42049085877
-
Inhibition of CCN6(Wnt-1-induced signaling protein 3) down-regulates E-cadherin in the breast epithelium through induction of snail and ZEB1
-
Huang W, Zhang Y, Varambally S, Chinnaiyan AM, Banerjee M, Merajver SD, et al. Inhibition of CCN6(Wnt-1-induced signaling protein 3) down-regulates E-cadherin in the breast epithelium through induction of snail and ZEB1. Am J Pathol 2008;172:893-904.
-
(2008)
Am J Pathol
, vol.172
, pp. 893-904
-
-
Huang, W.1
Zhang, Y.2
Varambally, S.3
Chinnaiyan, A.M.4
Banerjee, M.5
Merajver, S.D.6
-
8
-
-
2142646419
-
WISP3 (CCN6) is a secreted tumor-suppressor protein that modulates IGF signaling in inflammatory breast cancer
-
Kleer CG, Zhang Y, Pan Q, Merajver SD. WISP3 (CCN6) is a secreted tumor-suppressor protein that modulates IGF signaling in inflammatory breast cancer. Neoplasia 2004;6:179-85.
-
(2004)
Neoplasia
, vol.6
, pp. 179-185
-
-
Kleer, C.G.1
Zhang, Y.2
Pan, Q.3
Merajver, S.D.4
-
9
-
-
85047695306
-
WISP3 is a novel tumor suppressor gene of inflammatory breast cancer
-
Kleer CG, Zhang Y, Pan Q, van Golen KL,WuZF, Livant D, et al. WISP3 is a novel tumor suppressor gene of inflammatory breast cancer. Oncogene 2002;21:3172-80.
-
(2002)
Oncogene
, vol.21
, pp. 3172-3180
-
-
Kleer, C.G.1
Zhang, Y.2
Pan, Q.3
Van Golen, K.L.4
Wu, Z.F.5
Livant, D.6
-
10
-
-
67651151237
-
Matrix protein CCN1 is critical for prostate carcinoma cell proliferation and TRAIL-induced apoptosis
-
Franzen CA, Chen CC, Todorovic V, Juric V, Monzon RI, Lau LF. Matrix protein CCN1 is critical for prostate carcinoma cell proliferation and TRAIL-induced apoptosis. Mol Cancer Res 2009;7:1045-55.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1045-1055
-
-
Franzen, C.A.1
Chen, C.C.2
Todorovic, V.3
Juric, V.4
Monzon, R.I.5
Lau, L.F.6
-
11
-
-
47049116948
-
Involvement of hypoxia-inducing factor-1alpha-dependent plasminogen activator inhibitor-1 upregulation in Cyr61/CCN1-induced gastric cancer cell invasion
-
Lin MT, Kuo IH, Chang CC, Chu CY, Chen HY, Lin BR, et al. Involvement of hypoxia-inducing factor-1alpha-dependent plasminogen activator inhibitor-1 upregulation in Cyr61/CCN1-induced gastric cancer cell invasion. J Biol Chem 2008;283:15807-15.
-
(2008)
J Biol Chem
, vol.283
, pp. 15807-15815
-
-
Lin, M.T.1
Kuo, I.H.2
Chang, C.C.3
Chu, C.Y.4
Chen, H.Y.5
Lin, B.R.6
-
12
-
-
0032835343
-
A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype
-
van Golen KL, Davies S, Wu ZF, Wang Y, Bucana CD, Root H, et al. A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype. Clin Cancer Res 1999;5:2511-9.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2511-2519
-
-
Van Golen, K.L.1
Davies, S.2
Wu, Z.F.3
Wang, Y.4
Bucana, C.D.5
Root, H.6
-
13
-
-
47549090432
-
TGFbeta in cancer
-
Massague J. TGFbeta in cancer. Cell 2008;134:215-30.
-
(2008)
Cell
, vol.134
, pp. 215-230
-
-
Massague, J.1
-
14
-
-
77954862083
-
The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells
-
Taylor MA, Parvani JG, Schiemann WP. The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells. J Mammary Gland Biol Neoplasia 2010;15:169-90.
-
(2010)
J Mammary Gland Biol Neoplasia
, vol.15
, pp. 169-190
-
-
Taylor, M.A.1
Parvani, J.G.2
Schiemann, W.P.3
-
15
-
-
59449090107
-
TGF-beta-induced epithelial to mesenchymal transition
-
Xu J, Lamouille S, Derynck R. TGF-beta-induced epithelial to mesenchymal transition. Cell Res 2009;19:156-72.
-
(2009)
Cell Res
, vol.19
, pp. 156-172
-
-
Xu, J.1
Lamouille, S.2
Derynck, R.3
-
17
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-beta family signalling
-
Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 2003;425:577-84.
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
18
-
-
77649178841
-
The TAK1-TRAF6 signalling pathway
-
Landstrom M. The TAK1-TRAF6 signalling pathway. Int J Biochem Cell Biol 2010;42:585-9.
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 585-589
-
-
Landstrom, M.1
-
19
-
-
24944497786
-
Non-Smad TGF-beta signals
-
Moustakas A, Heldin CH. Non-Smad TGF-beta signals. J Cell Sci 2005;118:3573-84.
-
(2005)
J Cell Sci
, vol.118
, pp. 3573-3584
-
-
Moustakas, A.1
Heldin, C.H.2
-
20
-
-
52049111663
-
TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta
-
Yamashita M, Fatyol K, Jin C, Wang X, Liu Z, Zhang YE. TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta. Mol Cell 2008;31:918-24.
-
(2008)
Mol Cell
, vol.31
, pp. 918-924
-
-
Yamashita, M.1
Fatyol, K.2
Jin, C.3
Wang, X.4
Liu, Z.5
Zhang, Y.E.6
-
22
-
-
0037603113
-
Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
-
Debnath J, Muthuswamy SK, Brugge JS. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 2003;30:256-68.
-
(2003)
Methods
, vol.30
, pp. 256-268
-
-
Debnath, J.1
Muthuswamy, S.K.2
Brugge, J.S.3
-
23
-
-
0034010982
-
BMP-binding modules in chordin: A model for signalling regulation in the extracellular space
-
Larrain J, Bachiller D, Lu B, Agius E, Piccolo S, De Robertis EM. BMP-binding modules in chordin: a model for signalling regulation in the extracellular space. Development 2000;127:821-30.
-
(2000)
Development
, vol.127
, pp. 821-830
-
-
Larrain, J.1
Bachiller, D.2
Lu, B.3
Agius, E.4
Piccolo, S.5
De Robertis, E.M.6
-
24
-
-
0030598867
-
Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of chordin to BMP-4
-
Piccolo S, Sasai Y, Lu B, De Robertis EM. Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4. Cell 1996;86:589-98.
-
(1996)
Cell
, vol.86
, pp. 589-598
-
-
Piccolo, S.1
Sasai, Y.2
Lu, B.3
De Robertis, E.M.4
-
25
-
-
0141816752
-
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
-
Kleer CG, Cao Q, Varambally S, Shen R, Ota I, Tomlins SA, et al. EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells. Proc Natl Acad Sci U S A 2003;100:11606-11.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 11606-11611
-
-
Kleer, C.G.1
Cao, Q.2
Varambally, S.3
Shen, R.4
Ota, I.5
Tomlins, S.A.6
-
26
-
-
0038700565
-
Akt kinases in breast cancer and the results of adjuvant therapy
-
Stal O, Perez-Tenorio G, Akerberg L, Olsson B, Nordenskjold B, Skoog L, et al. Akt kinases in breast cancer and the results of adjuvant therapy. Breast Cancer Res 2003;5:R37-44.
-
(2003)
Breast Cancer Res
, vol.5
-
-
Stal, O.1
Perez-Tenorio, G.2
Akerberg, L.3
Olsson, B.4
Nordenskjold, B.5
Skoog, L.6
-
27
-
-
0004222021
-
Rosen's breast pathology
-
Rosen P, editor. 3rd ed. Philadelphia, PA: Lippincott Williams & Wilkins
-
Rosen PP. Rosen's breast pathology. In: Rosen P, editor. Rosen's breast pathology. 3rd ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2008. p. 325.
-
(2008)
Rosen's Breast Pathology
, pp. 325
-
-
Rosen, P.P.1
-
28
-
-
0030320654
-
The importance of the microenvironment in breast cancer progression: Recapitulation of mammary tumorigenesis using a unique human mammary epithelial cell model and a three-dimensional culture assay
-
Weaver VM, Fischer AH, Peterson OW, Bissell MJ. The importance of the microenvironment in breast cancer progression: recapitulation of mammary tumorigenesis using a unique human mammary epithelial cell model and a three-dimensional culture assay. Biochem Cell Biol 1996;74:833-51.
-
(1996)
Biochem Cell Biol
, vol.74
, pp. 833-851
-
-
Weaver, V.M.1
Fischer, A.H.2
Peterson, O.W.3
Bissell, M.J.4
-
29
-
-
79956105716
-
CCN6 (WISP3) decreases ZEB1-mediated EMT and invasion by attenuation of IGF-1 receptor signaling in breast cancer
-
Lorenzatti G, Huang W, Pal A, Cabanillas AM, Kleer CG. CCN6 (WISP3) decreases ZEB1-mediated EMT and invasion by attenuation of IGF-1 receptor signaling in breast cancer. J Cell Sci 2011;124:1752-8.
-
(2011)
J Cell Sci
, vol.124
, pp. 1752-1758
-
-
Lorenzatti, G.1
Huang, W.2
Pal, A.3
Cabanillas, A.M.4
Kleer, C.G.5
-
30
-
-
0036051343
-
Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta
-
Abreu JG, Ketpura NI, Reversade B, De Robertis EM. Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta. Nat Cell Biol 2002;4:599-604.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 599-604
-
-
Abreu, J.G.1
Ketpura, N.I.2
Reversade, B.3
De Robertis, E.M.4
-
31
-
-
54449100051
-
BMPER is an endothelial cell regulator and controls bone morphogenetic protein-4-dependent angiogenesis
-
Heinke J, Wehofsits L, Zhou Q, Zoeller C, Baar KM, Helbing T, et al. BMPER is an endothelial cell regulator and controls bone morphogenetic protein-4-dependent angiogenesis. Circ Res 2008;103:804-12.
-
(2008)
Circ Res
, vol.103
, pp. 804-812
-
-
Heinke, J.1
Wehofsits, L.2
Zhou, Q.3
Zoeller, C.4
Baar, K.M.5
Helbing, T.6
-
32
-
-
0043133835
-
BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation
-
Moser M, Binder O,WuY, Aitsebaomo J, Ren R, Bode C, et al.BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation. Mol Cell Biol 2003;23:5664-79.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5664-5679
-
-
Moser, M.1
Binder, O.2
Wu, Y.3
Aitsebaomo, J.4
Ren, R.5
Bode, C.6
-
33
-
-
0033619255
-
Silencing of TGF-beta signalling by the pseudoreceptor BAMBI
-
Onichtchouk D, Chen YG, Dosch R, Gawantka V, Delius H, Massague J, et al. Silencing of TGF-beta signalling by the pseudoreceptor BAMBI. Nature 1999;401:480-5.
-
(1999)
Nature
, vol.401
, pp. 480-485
-
-
Onichtchouk, D.1
Chen, Y.G.2
Dosch, R.3
Gawantka, V.4
Delius, H.5
Massague, J.6
-
34
-
-
1642523489
-
Helix-loop-helix proteins in mammary gland development and breast cancer
-
Desprez PY, Sumida T, Coppe JP. Helix-loop-helix proteins in mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia 2003;8:225-39.
-
(2003)
J Mammary Gland Biol Neoplasia
, vol.8
, pp. 225-239
-
-
Desprez, P.Y.1
Sumida, T.2
Coppe, J.P.3
-
35
-
-
0033531948
-
Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein-and activin-mediated growth arrest and apoptosis in B cells
-
Ishisaki A, Yamato K, Hashimoto S, Nakao A, Tamaki K, Nonaka K, et al. Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein-and activin-mediated growth arrest and apoptosis in B cells. J Biol Chem 1999;274:13637-42.
-
(1999)
J Biol Chem
, vol.274
, pp. 13637-13642
-
-
Ishisaki, A.1
Yamato, K.2
Hashimoto, S.3
Nakao, A.4
Tamaki, K.5
Nonaka, K.6
-
36
-
-
33845906843
-
All in the CCN family: Essential matricellular signaling modulators emerge from the bunker
-
Leask A, Abraham DJ. All in the CCN family: essential matricellular signaling modulators emerge from the bunker. J Cell Sci 2006;119:4803-10.
-
(2006)
J Cell Sci
, vol.119
, pp. 4803-4810
-
-
Leask, A.1
Abraham, D.J.2
-
37
-
-
34948831652
-
The CCN family member Wisp3, mutant in progressive pseudorheumatoid dysplasia, modulates BMP and Wnt signaling
-
Nakamura Y, Weidinger G, Liang JO, Aquilina-Beck A, Tamai K, Moon RT, et al. The CCN family member Wisp3, mutant in progressive pseudorheumatoid dysplasia, modulates BMP and Wnt signaling. J Clin Invest 2007;117:3075-86.
-
(2007)
J Clin Invest
, vol.117
, pp. 3075-3086
-
-
Nakamura, Y.1
Weidinger, G.2
Liang, J.O.3
Aquilina-Beck, A.4
Tamai, K.5
Moon, R.T.6
-
38
-
-
0029149656
-
Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse
-
Winnier G, Blessing M, Labosky PA, Hogan BL. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev 1995;9:2105-16.
-
(1995)
Genes Dev
, vol.9
, pp. 2105-2116
-
-
Winnier, G.1
Blessing, M.2
Labosky, P.A.3
Hogan, B.L.4
-
39
-
-
79961006281
-
Human ovarian carcinoma-associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production
-
McLean K, Gong Y, Choi Y, Deng N, Yang K, Bai S, et al. Human ovarian carcinoma-associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production. J Clin Invest 2011;121:3206-19.
-
(2011)
J Clin Invest
, vol.121
, pp. 3206-3219
-
-
McLean, K.1
Gong, Y.2
Choi, Y.3
Deng, N.4
Yang, K.5
Bai, S.6
-
40
-
-
12544259720
-
Bone morphogenic proteins are overexpressed in malignant melanoma and promote cell invasion and migration
-
Rothhammer T, Poser I, Soncin F, Bataille F, Moser M, Bosserhoff AK. Bone morphogenic proteins are overexpressed in malignant melanoma and promote cell invasion and migration. Cancer Res 2005;65:448-56.
-
(2005)
Cancer Res
, vol.65
, pp. 448-456
-
-
Rothhammer, T.1
Poser, I.2
Soncin, F.3
Bataille, F.4
Moser, M.5
Bosserhoff, A.K.6
-
41
-
-
0141594935
-
From developmental disorder to heritable cancer: It's all in the BMP/TGF-beta family
-
Waite KA, Eng C. From developmental disorder to heritable cancer: it's all in the BMP/TGF-beta family. Nat Rev Genet 2003;4:763-73.
-
(2003)
Nat Rev Genet
, vol.4
, pp. 763-773
-
-
Waite, K.A.1
Eng, C.2
-
42
-
-
84863419728
-
TAK1 inhibition promotes apoptosis in KRAS-dependent colon cancers
-
Singh A, Sweeney MF, Yu M, Burger A, Greninger P, Benes C, et al. TAK1 inhibition promotes apoptosis in KRAS-dependent colon cancers. Cell 2012;148:639-50.
-
(2012)
Cell
, vol.148
, pp. 639-650
-
-
Singh, A.1
Sweeney, M.F.2
Yu, M.3
Burger, A.4
Greninger, P.5
Benes, C.6
-
43
-
-
79961223562
-
Modulation of pancreatic cancer chemoresistance by inhibition of TAK1
-
Melisi D, Xia Q, Paradiso G, Ling J, Moccia T, Carbone C, et al. Modulation of pancreatic cancer chemoresistance by inhibition of TAK1. J Natl Cancer Inst 2011;103:1190-204.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 1190-1204
-
-
Melisi, D.1
Xia, Q.2
Paradiso, G.3
Ling, J.4
Moccia, T.5
Carbone, C.6
|