Curcumin inhibits thrombin-stimulated connective tissue growth factor (CTGF/CCN2) production through c-Jun NH2-terminal kinase suppression in human gingival fibroblasts

Journal of Periodontology

Volumn 83, Issue 12, 2012, Pages 1546-1553

  Chen, Yi Wen ^a   Yang, Wan Hsien ^a   Wong, Man Ying ^a   Chang, Hao Hueng ^a   Kuo, Mark Yen Ping ^a,b  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Connective tissue growth factor; Curcumin; Fibroblasts; Gingival overgrowth; Thrombin; Wound healing

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; CONNECTIVE TISSUE GROWTH FACTOR; CURCUMIN; ENZYME INHIBITOR; PROTEINASE ACTIVATED RECEPTOR; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; THROMBIN;

ARTICLE; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; FIBROBLAST; GINGIVA; GINGIVA OVERGROWTH; HUMAN; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

CELLS, CULTURED; CONNECTIVE TISSUE GROWTH FACTOR; CURCUMIN; ENZYME ACTIVATION; ENZYME INHIBITORS; FIBROBLASTS; GINGIVA; GINGIVAL OVERGROWTH; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE KINASE 5; MAP KINASE SIGNALING SYSTEM; REACTIVE OXYGEN SPECIES; RECEPTORS, PROTEINASE-ACTIVATED; THROMBIN;

EID: 84871085082     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2012.110641     Document Type: Article

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