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Volumn 180, Issue 6, 2012, Pages 2386-2403

Connective tissue growth factor causes glaucoma by modifying the actin cytoskeleton of the trabecular meshwork

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CONNECTIVE TISSUE GROWTH FACTOR; FASUDIL; FIBRONECTIN;

EID: 84861584720     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.02.030     Document Type: Article
Times cited : (181)

References (94)
  • 3
    • 79954621581 scopus 로고    scopus 로고
    • Glaucoma
    • H.A. Quigley Glaucoma Lancet 377 2011 1367 1377
    • (2011) Lancet , vol.377 , pp. 1367-1377
    • Quigley, H.A.1
  • 4
    • 0032189334 scopus 로고    scopus 로고
    • The effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucoma
    • Collaborative Normal-Tension Glaucoma Study Group
    • Collaborative Normal-Tension Glaucoma Study Group The effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucoma Am J Ophthalmol 126 1998 498 505
    • (1998) Am J Ophthalmol , vol.126 , pp. 498-505
  • 5
    • 0032189255 scopus 로고    scopus 로고
    • Comparison of glaucomatous progression between untreated patients with normal-tension glaucoma and patients with therapeutically reduced intraocular pressures
    • Collaborative Normal-Tension Glaucoma Study Group
    • Collaborative Normal-Tension Glaucoma Study Group Comparison of glaucomatous progression between untreated patients with normal-tension glaucoma and patients with therapeutically reduced intraocular pressures Am J Ophthalmol 126 1998 487 497
    • (1998) Am J Ophthalmol , vol.126 , pp. 487-497
  • 7
    • 2942596469 scopus 로고    scopus 로고
    • The Ocular Hypertension Treatment Study: Topical medication delays or prevents primary open-angle glaucoma in African American individuals
    • E.J. Higginbotham, M.O. Gordon, J.A. Beiser, M.V. Drake, G.R. Bennett, M.R. Wilson, M.A. Kass The Ocular Hypertension Treatment Study: topical medication delays or prevents primary open-angle glaucoma in African American individuals Arch Ophthalmol 122 2004 813 820
    • (2004) Arch Ophthalmol , vol.122 , pp. 813-820
    • Higginbotham, E.J.1    Gordon, M.O.2    Beiser, J.A.3    Drake, M.V.4    Bennett, G.R.5    Wilson, M.R.6    Kass, M.A.7
  • 8
    • 0037251618 scopus 로고    scopus 로고
    • Factors for glaucoma progression and the effect of treatment: The early manifest glaucoma trial
    • M.C. Leske, A. Heijl, M. Hussein, B. Bengtsson, L. Hyman, E. Komaroff Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trial Arch Ophthalmol 121 2003 48 56
    • (2003) Arch Ophthalmol , vol.121 , pp. 48-56
    • Leske, M.C.1    Heijl, A.2    Hussein, M.3    Bengtsson, B.4    Hyman, L.5    Komaroff, E.6
  • 9
    • 0033808223 scopus 로고    scopus 로고
    • The advanced glaucoma intervention study (AGIS), 7: The relationship between control of intraocular pressure and visual field deterioration
    • The AGIS Investigators
    • The AGIS Investigators The advanced glaucoma intervention study (AGIS), 7: the relationship between control of intraocular pressure and visual field deterioration Am J Ophthalmol 130 2000 429 440
    • (2000) Am J Ophthalmol , vol.130 , pp. 429-440
  • 10
    • 0016240481 scopus 로고
    • Effect of intraocular pressure on rapid axoplasmic transport in monkey optic nerve
    • D.R. Anderson, A. Hendrickson Effect of intraocular pressure on rapid axoplasmic transport in monkey optic nerve Invest Ophthalmol 13 1974 771 783
    • (1974) Invest Ophthalmol , vol.13 , pp. 771-783
    • Anderson, D.R.1    Hendrickson, A.2
  • 14
    • 64249131959 scopus 로고    scopus 로고
    • The trabecular meshwork outflow pathways: Structural and functional aspects
    • E.R. Tamm The trabecular meshwork outflow pathways: structural and functional aspects Exp Eye Res 88 2009 648 655
    • (2009) Exp Eye Res , vol.88 , pp. 648-655
    • Tamm, E.R.1
  • 15
    • 64249083215 scopus 로고    scopus 로고
    • Uveoscleral outflow: A review
    • A. Alm, S.F. Nilsson Uveoscleral outflow: a review Exp Eye Res 88 2009 760 768
    • (2009) Exp Eye Res , vol.88 , pp. 760-768
    • Alm, A.1    Nilsson, S.F.2
  • 16
    • 31044448209 scopus 로고    scopus 로고
    • What controls aqueous humour outflow resistance?
    • M. Johnson 'What controls aqueous humour outflow resistance?' Exp Eye Res 82 2006 545 557
    • (2006) Exp Eye Res , vol.82 , pp. 545-557
    • Johnson, M.1
  • 17
    • 64249161403 scopus 로고    scopus 로고
    • Structural changes of the trabecular meshwork in different kinds of glaucoma
    • O.Y. Tektas, E. Lütjen-Drecoll Structural changes of the trabecular meshwork in different kinds of glaucoma Exp Eye Res 88 2009 769 775
    • (2009) Exp Eye Res , vol.88 , pp. 769-775
    • Tektas, O.Y.1    Lütjen-Drecoll, E.2
  • 18
    • 0035679256 scopus 로고    scopus 로고
    • Ultrastructural localization of collagen IV, fibronectin, and laminin in the trabecular meshwork of normal and glaucomatous eyes
    • C.R. Hann, M.J. Springett, X. Wang, D.H. Johnson Ultrastructural localization of collagen IV, fibronectin, and laminin in the trabecular meshwork of normal and glaucomatous eyes Ophthalmic Res 33 2001 314 324
    • (2001) Ophthalmic Res , vol.33 , pp. 314-324
    • Hann, C.R.1    Springett, M.J.2    Wang, X.3    Johnson, D.H.4
  • 19
    • 0024543236 scopus 로고
    • Immunomicroscopical study of type VI collagen in the trabecular meshwork of normal and glaucomatous eyes
    • E. Lütjen-Drecoll, M. Rittig, J. Rauterberg, R. Jander, J. Mollenhauer Immunomicroscopical study of type VI collagen in the trabecular meshwork of normal and glaucomatous eyes Exp Eye Res 48 1989 139 147
    • (1989) Exp Eye Res , vol.48 , pp. 139-147
    • Lütjen-Drecoll, E.1    Rittig, M.2    Rauterberg, J.3    Jander, R.4    Mollenhauer, J.5
  • 21
    • 0030942119 scopus 로고    scopus 로고
    • Severity of optic nerve damage in eyes with POAG is correlated with changes in the trabecular meshwork
    • J. Gottanka, D.H. Johnson, P. Martus, E. Lütjen-Drecoll Severity of optic nerve damage in eyes with POAG is correlated with changes in the trabecular meshwork J Glaucoma 6 1997 123 132
    • (1997) J Glaucoma , vol.6 , pp. 123-132
    • Gottanka, J.1    Johnson, D.H.2    Martus, P.3    Lütjen-Drecoll, E.4
  • 22
    • 64249129112 scopus 로고    scopus 로고
    • The role of the actomyosin system in regulating trabecular fluid outflow
    • B. Tian, B.T. Gabelt, B. Geiger, P.L. Kaufman The role of the actomyosin system in regulating trabecular fluid outflow Exp Eye Res 88 2009 713 717
    • (2009) Exp Eye Res , vol.88 , pp. 713-717
    • Tian, B.1    Gabelt, B.T.2    Geiger, B.3    Kaufman, P.L.4
  • 24
    • 0034002380 scopus 로고    scopus 로고
    • The regulation of trabecular meshwork and ciliary muscle contractility
    • M. Wiederholt, H. Thieme, F. Stumpff The regulation of trabecular meshwork and ciliary muscle contractility Prog Retin Eye Res 19 2000 271 295
    • (2000) Prog Retin Eye Res , vol.19 , pp. 271-295
    • Wiederholt, M.1    Thieme, H.2    Stumpff, F.3
  • 25
    • 34249694646 scopus 로고    scopus 로고
    • Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma
    • V.P. Rao, D.L. Epstein Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma BioDrugs 21 2007 167 177
    • (2007) BioDrugs , vol.21 , pp. 167-177
    • Rao, V.P.1    Epstein, D.L.2
  • 27
    • 33750128159 scopus 로고    scopus 로고
    • Transforming growth factor-beta levels in human aqueous humor of glaucomatous, diabetic and uveitic eyes
    • S.H. Min, T.I. Lee, Y.S. Chung, H.K. Kim Transforming growth factor-beta levels in human aqueous humor of glaucomatous, diabetic and uveitic eyes Korean J Ophthalmol 20 2006 162 165
    • (2006) Korean J Ophthalmol , vol.20 , pp. 162-165
    • Min, S.H.1    Lee, T.I.2    Chung, Y.S.3    Kim, H.K.4
  • 28
    • 0036282046 scopus 로고    scopus 로고
    • Higher concentration of transforming growth factor-beta in aqueous humor of glaucomatous eyes and diabetic eyes
    • Y. Ochiai, H. Ochiai Higher concentration of transforming growth factor-beta in aqueous humor of glaucomatous eyes and diabetic eyes Jpn J Ophthalmol 46 2002 249 253
    • (2002) Jpn J Ophthalmol , vol.46 , pp. 249-253
    • Ochiai, Y.1    Ochiai, H.2
  • 29
    • 1842425818 scopus 로고    scopus 로고
    • The aqueous levels of TGF-beta2 in patients with glaucoma
    • A.A. Ozcan, N. Ozdemir, A. Canataroglu The aqueous levels of TGF-beta2 in patients with glaucoma Int Ophthalmol 25 2004 19 22
    • (2004) Int Ophthalmol , vol.25 , pp. 19-22
    • Ozcan, A.A.1    Ozdemir, N.2    Canataroglu, A.3
  • 30
    • 0035021939 scopus 로고    scopus 로고
    • Transforming growth factor-β2 levels in the aqueous humor in different types of glaucoma and the relation to filtering bleb development
    • G. Picht, U. Welge-Luessen, F. Grehn, E. Lütjen-Drecoll Transforming growth factor-β2 levels in the aqueous humor in different types of glaucoma and the relation to filtering bleb development Graefes Arch Clin Exp Ophthalmol 239 2001 199 207
    • (2001) Graefes Arch Clin Exp Ophthalmol , vol.239 , pp. 199-207
    • Picht, G.1    Welge-Luessen, U.2    Grehn, F.3    Lütjen-Drecoll, E.4
  • 31
    • 0028592628 scopus 로고
    • Aqueous humor in glaucomatous eyes contains an increased level of TGF-β2
    • R.C. Tripathi, J. Li, W.F.A. Chan, B.J. Tripathi Aqueous humor in glaucomatous eyes contains an increased level of TGF-β2 Exp Eye Res 58 1994 723 727
    • (1994) Exp Eye Res , vol.58 , pp. 723-727
    • Tripathi, R.C.1    Li, J.2    Chan, W.F.A.3    Tripathi, B.J.4
  • 32
    • 80054865277 scopus 로고    scopus 로고
    • Influence of race and age on aqueous humor levels of transforming growth factor-beta 2 in glaucomatous and nonglaucomatous eyes
    • R.H. Trivedi, M. Nutaitis, D. Vroman, C.E. Crosson Influence of race and age on aqueous humor levels of transforming growth factor-beta 2 in glaucomatous and nonglaucomatous eyes J Ocul Pharmacol Ther 27 2011 477 480
    • (2011) J Ocul Pharmacol Ther , vol.27 , pp. 477-480
    • Trivedi, R.H.1    Nutaitis, M.2    Vroman, D.3    Crosson, C.E.4
  • 33
    • 18644379971 scopus 로고    scopus 로고
    • Concentration of transforming growth factor beta2 in aqueous humor
    • N. Yamamoto, K. Itonaga, T. Marunouchi, K. Majima Concentration of transforming growth factor beta2 in aqueous humor Ophthalmic Res 37 2005 29 33
    • (2005) Ophthalmic Res , vol.37 , pp. 29-33
    • Yamamoto, N.1    Itonaga, K.2    Marunouchi, T.3    Majima, K.4
  • 34
    • 20544468453 scopus 로고    scopus 로고
    • Morphological changes in glaucomatous eyes and the role of TGFbeta2 for the pathogenesis of the disease
    • E. Lütjen-Drecoll Morphological changes in glaucomatous eyes and the role of TGFbeta2 for the pathogenesis of the disease Exp Eye Res 81 2005 1 4
    • (2005) Exp Eye Res , vol.81 , pp. 1-4
    • Lütjen-Drecoll, E.1
  • 35
    • 35848942149 scopus 로고    scopus 로고
    • What increases outflow resistance in primary open-angle glaucoma?
    • E.R. Tamm, R. Fuchshofer What increases outflow resistance in primary open-angle glaucoma? Surv Ophthalmol 52 Suppl 2 2007 S101 S104
    • (2007) Surv Ophthalmol , vol.52 , Issue.SUPPL. 2
    • Tamm, E.R.1    Fuchshofer, R.2
  • 36
    • 64249156465 scopus 로고    scopus 로고
    • Modulation of extracellular matrix turnover in the trabecular meshwork
    • R. Fuchshofer, E.R. Tamm Modulation of extracellular matrix turnover in the trabecular meshwork Exp Eye Res 88 2009 683 688
    • (2009) Exp Eye Res , vol.88 , pp. 683-688
    • Fuchshofer, R.1    Tamm, E.R.2
  • 37
    • 0036845687 scopus 로고    scopus 로고
    • Signaling mechanism of TGF-beta1-induced collagen contraction mediated by bovine trabecular meshwork cells
    • Y. Nakamura, S. Hirano, K. Suzuki, K. Seki, T. Sagara, T. Nishida Signaling mechanism of TGF-beta1-induced collagen contraction mediated by bovine trabecular meshwork cells Invest Ophthalmol Vis Sci 43 2002 3465 3472
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 3465-3472
    • Nakamura, Y.1    Hirano, S.2    Suzuki, K.3    Seki, K.4    Sagara, T.5    Nishida, T.6
  • 38
    • 0029936704 scopus 로고    scopus 로고
    • Transforming growth factor-β1 induces α-smooth muscle-actin expression in cultured human and monkey trabecular meshwork
    • E.R. Tamm, A. Siegner, A. Baur, E. Lütjen-Drecoll Transforming growth factor-β1 induces α-smooth muscle-actin expression in cultured human and monkey trabecular meshwork Exp Eye Res 62 1996 389 397
    • (1996) Exp Eye Res , vol.62 , pp. 389-397
    • Tamm, E.R.1    Siegner, A.2    Baur, A.3    Lütjen-Drecoll, E.4
  • 39
    • 67349178647 scopus 로고    scopus 로고
    • Connective tissue growth factor induces extracellular matrix deposition in human trabecular meshwork cells
    • B. Junglas, A.H. Yu, U. Welge-Lussen, E.R. Tamm, R. Fuchshofer Connective tissue growth factor induces extracellular matrix deposition in human trabecular meshwork cells Exp Eye Res 88 2009 1065 1075
    • (2009) Exp Eye Res , vol.88 , pp. 1065-1075
    • Junglas, B.1    Yu, A.H.2    Welge-Lussen, U.3    Tamm, E.R.4    Fuchshofer, R.5
  • 40
    • 0036838772 scopus 로고    scopus 로고
    • Pathogenesis of fibrosis: Role of TGF-β and CTGF
    • H. Ihn Pathogenesis of fibrosis: role of TGF-β and CTGF Curr Opin Rheumatol 14 2002 681 685
    • (2002) Curr Opin Rheumatol , vol.14 , pp. 681-685
    • Ihn, H.1
  • 41
    • 70849136597 scopus 로고    scopus 로고
    • Connective tissue growth factor-(CTGF. CCN2)-a marker, mediator and therapeutic target for renal fibrosis
    • M.K. Phanish, S.K. Winn, M.E. Dockrell Connective tissue growth factor-(CTGF. CCN2)-a marker, mediator and therapeutic target for renal fibrosis Nephron Exp Nephrol 114 2009 e83 e92
    • (2009) Nephron Exp Nephrol , vol.114
    • Phanish, M.K.1    Winn, S.K.2    Dockrell, M.E.3
  • 42
  • 43
  • 45
    • 74849101559 scopus 로고    scopus 로고
    • Norrin promotes vascular regrowth after oxygen-induced retinal vessel loss and suppresses retinopathy in mice
    • A. Ohlmann, R. Seitz, B. Braunger, D. Seitz, M.R. Bosl, E.R. Tamm Norrin promotes vascular regrowth after oxygen-induced retinal vessel loss and suppresses retinopathy in mice J Neurosci 30 2010 183 193
    • (2010) J Neurosci , vol.30 , pp. 183-193
    • Ohlmann, A.1    Seitz, R.2    Braunger, B.3    Seitz, D.4    Bosl, M.R.5    Tamm, E.R.6
  • 46
    • 0035065567 scopus 로고    scopus 로고
    • A simple polymerase chain reaction assay for genotyping the retinal degeneration mutation (Pdeb(rd1)) in FVB/N-derived transgenic mice
    • E. Gimenez, L. Montoliu A simple polymerase chain reaction assay for genotyping the retinal degeneration mutation (Pdeb(rd1)) in FVB/N-derived transgenic mice Lab Anim 35 2001 153 156
    • (2001) Lab Anim , vol.35 , pp. 153-156
    • Gimenez, E.1    Montoliu, L.2
  • 47
    • 33847709462 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 is an antagonist of transforming growth factor-beta2 in human trabecular meshwork cells
    • R. Fuchshofer, A.H. Yu, U. Welge-Lüssen, E.R. Tamm Bone morphogenetic protein-7 is an antagonist of transforming growth factor-beta2 in human trabecular meshwork cells Invest Ophthalmol Vis Sci 48 2007 715 726
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 715-726
    • Fuchshofer, R.1    Yu, A.H.2    Welge-Lüssen, U.3    Tamm, E.R.4
  • 48
    • 0028123512 scopus 로고
    • Preliminary characterization of a transformed cell strain derived from human trabecular meshwork
    • I.-H. Pang, D.L. Shade, A.F. Clark, H.T. Steely, L. Desantis Preliminary characterization of a transformed cell strain derived from human trabecular meshwork Curr Eye Res 13 1994 51 63
    • (1994) Curr Eye Res , vol.13 , pp. 51-63
    • Pang, I.-H.1    Shade, D.L.2    Clark, A.F.3    Steely, H.T.4    Desantis, L.5
  • 49
    • 0029847454 scopus 로고    scopus 로고
    • Human and monkey trabecular meshwork accumulate alpha B-crystallin in response to heat shock and oxidative stress
    • E.R. Tamm, P. Russell, D.H. Johnson, J. Piatigorsky Human and monkey trabecular meshwork accumulate alpha B-crystallin in response to heat shock and oxidative stress Invest Ophthalmol Vis Sci 37 1996 2402 2413
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 2402-2413
    • Tamm, E.R.1    Russell, P.2    Johnson, D.H.3    Piatigorsky, J.4
  • 50
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • J. Vandesompele, K. De Preter, F. Pattyn, B. Poppe, N. Van Roy, A. De Paepe, F. Speleman Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes Genome Biol 3 2002 RESEARCH0034
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6    Speleman, F.7
  • 51
    • 0001166951 scopus 로고
    • A formaldehyde-glutaraldehyde fixative of high osmolality for use in electron-microscopy
    • M.J. Karnovsky A formaldehyde-glutaraldehyde fixative of high osmolality for use in electron-microscopy J Cell Biol 27 1965 137 138
    • (1965) J Cell Biol , vol.27 , pp. 137-138
    • Karnovsky, M.J.1
  • 52
    • 84907126089 scopus 로고
    • Embedding in epoxy resins for ultrathin sectioning in electron microscopy
    • K.C. Richardson, L. Jarret, H. Finke Embedding in epoxy resins for ultrathin sectioning in electron microscopy Stain Technol 35 1960 313 323
    • (1960) Stain Technol , vol.35 , pp. 313-323
    • Richardson, K.C.1    Jarret, L.2    Finke, H.3
  • 53
    • 43749123967 scopus 로고
    • Über das Paraphenylendiamin in der histologischen Färbetechnik und über eine neue Schnellfärbemethode der Nervenmarkscheide am Gefrierschnitt
    • W.H. Schultze Über das Paraphenylendiamin in der histologischen Färbetechnik und über eine neue Schnellfärbemethode der Nervenmarkscheide am Gefrierschnitt Zentralbl Pathol 36 1972 639 640
    • (1972) Zentralbl Pathol , vol.36 , pp. 639-640
    • Schultze, W.H.1
  • 54
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: Biochemistry and biology
    • A.B. Jaffe, A. Hall Rho GTPases: biochemistry and biology Annu Rev Cell Dev Biol 21 2005 247 269
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 55
    • 0026778133 scopus 로고
    • The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
    • A.J. Ridley, A. Hall The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors Cell 70 1992 389 399
    • (1992) Cell , vol.70 , pp. 389-399
    • Ridley, A.J.1    Hall, A.2
  • 56
    • 31144475398 scopus 로고    scopus 로고
    • Viral gene therapy strategies: From basic science to clinical application
    • L.S. Young, P.F. Searle, D. Onion, V. Mautner Viral gene therapy strategies: from basic science to clinical application J Pathol 208 2006 299 318
    • (2006) J Pathol , vol.208 , pp. 299-318
    • Young, L.S.1    Searle, P.F.2    Onion, D.3    Mautner, V.4
  • 57
    • 0029893374 scopus 로고    scopus 로고
    • Developmental regulation of the chicken βb1-crystallin promoter in transgenic mice
    • M.K. Duncan, X. Li, H. Ogino, K. Yasuda, J. Piatigorsky Developmental regulation of the chicken βB1-crystallin promoter in transgenic mice Mech Dev 57 1996 79 89
    • (1996) Mech Dev , vol.57 , pp. 79-89
    • Duncan, M.K.1    Li, X.2    Ogino, H.3    Yasuda, K.4    Piatigorsky, J.5
  • 59
    • 0035066006 scopus 로고    scopus 로고
    • Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632
    • P.V. Rao, P.F. Deng, J. Kumar, D.L. Epstein Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632 Invest Ophthalmol Vis Sci 42 2001 1029 1037
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 1029-1037
    • Rao, P.V.1    Deng, P.F.2    Kumar, J.3    Epstein, D.L.4
  • 60
    • 0035971161 scopus 로고    scopus 로고
    • The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts
    • C.C. Chen, N. Chen, L.F. Lau The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts J Biol Chem 276 2001 10443 10452
    • (2001) J Biol Chem , vol.276 , pp. 10443-10452
    • Chen, C.C.1    Chen, N.2    Lau, L.F.3
  • 64
    • 52449129589 scopus 로고    scopus 로고
    • CCN2 (Connective Tissue Growth Factor) is essential for extracellular matrix production and integrin signaling in chondrocytes
    • T. Nishida, H. Kawaki, R.M. Baxter, R.A. Deyoung, M. Takigawa, K.M. Lyons CCN2 (Connective Tissue Growth Factor) is essential for extracellular matrix production and integrin signaling in chondrocytes J Cell Commun Signal 1 2007 45 58
    • (2007) J Cell Commun Signal , vol.1 , pp. 45-58
    • Nishida, T.1    Kawaki, H.2    Baxter, R.M.3    Deyoung, R.A.4    Takigawa, M.5    Lyons, K.M.6
  • 65
    • 80052516404 scopus 로고    scopus 로고
    • Connective tissue growth factor modulates podocyte actin cytoskeleton and extracellular matrix synthesis and is induced in podocytes upon injury
    • R. Fuchshofer, S. Ullmann, L.F. Zeilbeck, M. Baumann, B. Junglas, E.R. Tamm Connective tissue growth factor modulates podocyte actin cytoskeleton and extracellular matrix synthesis and is induced in podocytes upon injury Histochem Cell Biol 136 2011 301 319
    • (2011) Histochem Cell Biol , vol.136 , pp. 301-319
    • Fuchshofer, R.1    Ullmann, S.2    Zeilbeck, L.F.3    Baumann, M.4    Junglas, B.5    Tamm, E.R.6
  • 66
    • 34848907421 scopus 로고    scopus 로고
    • Actin up: Regulation of podocyte structure and function by components of the actin cytoskeleton
    • C. Faul, K. Asanuma, E. Yanagida-Asanuma, K. Kim, P. Mundel Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton Trends Cell Biol 17 2007 428 437
    • (2007) Trends Cell Biol , vol.17 , pp. 428-437
    • Faul, C.1    Asanuma, K.2    Yanagida-Asanuma, E.3    Kim, K.4    Mundel, P.5
  • 67
    • 33749235728 scopus 로고    scopus 로고
    • Regulation of connective tissue growth factor expression in the aqueous humor outflow pathway
    • S.M. Chudgar, P. Deng, R. Maddala, D.L. Epstein, P.V. Rao Regulation of connective tissue growth factor expression in the aqueous humor outflow pathway Mol Vis 12 2006 1117 1126
    • (2006) Mol Vis , vol.12 , pp. 1117-1126
    • Chudgar, S.M.1    Deng, P.2    Maddala, R.3    Epstein, D.L.4    Rao, P.V.5
  • 68
    • 0035965308 scopus 로고    scopus 로고
    • Fibroblasts in mechanically stressed collagen lattices assume a "synthetic" phenotype
    • D. Kessler, S. Dethlefsen, I. Haase, M. Plomann, F. Hirche, T. Krieg, B. Eckes Fibroblasts in mechanically stressed collagen lattices assume a "synthetic" phenotype J Biol Chem 276 2001 36575 36585
    • (2001) J Biol Chem , vol.276 , pp. 36575-36585
    • Kessler, D.1    Dethlefsen, S.2    Haase, I.3    Plomann, M.4    Hirche, F.5    Krieg, T.6    Eckes, B.7
  • 69
    • 0036346511 scopus 로고    scopus 로고
    • Mechanical stress is required for high-level expression of connective tissue growth factor
    • C. Schild, B. Trueb Mechanical stress is required for high-level expression of connective tissue growth factor Exp Cell Res 274 2002 83 91
    • (2002) Exp Cell Res , vol.274 , pp. 83-91
    • Schild, C.1    Trueb, B.2
  • 70
    • 1642587806 scopus 로고    scopus 로고
    • Three members of the connective tissue growth factor family CCN are differentially regulated by mechanical stress
    • C. Schild, B. Trueb Three members of the connective tissue growth factor family CCN are differentially regulated by mechanical stress Biochim Biophys Acta 1691 2004 33 40
    • (2004) Biochim Biophys Acta , vol.1691 , pp. 33-40
    • Schild, C.1    Trueb, B.2
  • 71
    • 35348945277 scopus 로고    scopus 로고
    • A single bout of exercise with high mechanical loading induces the expression of Cyr61/CCN1 and CTGF/CCN2 in human skeletal muscle
    • R. Kivela, H. Kyrolainen, H. Selanne, P.V. Komi, H. Kainulainen, V. Vihko A single bout of exercise with high mechanical loading induces the expression of Cyr61/CCN1 and CTGF/CCN2 in human skeletal muscle J Appl Physiol 103 2007 1395 1401
    • (2007) J Appl Physiol , vol.103 , pp. 1395-1401
    • Kivela, R.1    Kyrolainen, H.2    Selanne, H.3    Komi, P.V.4    Kainulainen, H.5    Vihko, V.6
  • 72
    • 0141750631 scopus 로고    scopus 로고
    • Cyclic tensile strain and cyclic hydrostatic pressure differentially regulate expression of hypertrophic markers in primary chondrocytes
    • M. Wong, M. Siegrist, K. Goodwin Cyclic tensile strain and cyclic hydrostatic pressure differentially regulate expression of hypertrophic markers in primary chondrocytes Bone 33 2003 685 693
    • (2003) Bone , vol.33 , pp. 685-693
    • Wong, M.1    Siegrist, M.2    Goodwin, K.3
  • 74
    • 0035907365 scopus 로고    scopus 로고
    • Static pressure regulates connective tissue growth factor expression in human mesangial cells
    • K. Hishikawa, B.S. Oemar, T. Nakaki Static pressure regulates connective tissue growth factor expression in human mesangial cells J Biol Chem 276 2001 16797 16803
    • (2001) J Biol Chem , vol.276 , pp. 16797-16803
    • Hishikawa, K.1    Oemar, B.S.2    Nakaki, T.3
  • 75
    • 0033957976 scopus 로고    scopus 로고
    • Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis
    • B.L. Riser, M. Denichilo, P. Cortes, C. Baker, J.M. Grondin, J. Yee, R.G. Narins Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis J Am Soc Nephrol 11 2000 25 38
    • (2000) J Am Soc Nephrol , vol.11 , pp. 25-38
    • Riser, B.L.1    Denichilo, M.2    Cortes, P.3    Baker, C.4    Grondin, J.M.5    Yee, J.6    Narins, R.G.7
  • 77
    • 0035159094 scopus 로고    scopus 로고
    • Alpha-smooth muscle actin expression upregulates fibroblast contractile activity
    • B. Hinz, G. Celetta, J.J. Tomasek, G. Gabbiani, C. Chaponnier Alpha-smooth muscle actin expression upregulates fibroblast contractile activity Mol Biol Cell 12 2001 2730 2741
    • (2001) Mol Biol Cell , vol.12 , pp. 2730-2741
    • Hinz, B.1    Celetta, G.2    Tomasek, J.J.3    Gabbiani, G.4    Chaponnier, C.5
  • 78
    • 0035152098 scopus 로고    scopus 로고
    • The fibronexus in reactive and tumoral myofibroblasts: Further characterisation by electron microscopy
    • B. Eyden The fibronexus in reactive and tumoral myofibroblasts: further characterisation by electron microscopy Histol Histopathol 16 2001 57 70
    • (2001) Histol Histopathol , vol.16 , pp. 57-70
    • Eyden, B.1
  • 79
    • 0142027011 scopus 로고    scopus 로고
    • Mechanisms of force generation and transmission by myofibroblasts
    • B. Hinz, G. Gabbiani Mechanisms of force generation and transmission by myofibroblasts Curr Opin Biotechnol 14 2003 538 546
    • (2003) Curr Opin Biotechnol , vol.14 , pp. 538-546
    • Hinz, B.1    Gabbiani, G.2
  • 81
    • 2942568661 scopus 로고    scopus 로고
    • The mouse anterior chamber angle and trabecular meshwork develop without cell death
    • R.S. Smith, A. Zabaleta, O.V. Savinova, S.W. John The mouse anterior chamber angle and trabecular meshwork develop without cell death BMC Dev Biol 1 2001 3
    • (2001) BMC Dev Biol , vol.1 , pp. 3
    • Smith, R.S.1    Zabaleta, A.2    Savinova, O.V.3    John, S.W.4
  • 85
    • 79251516379 scopus 로고    scopus 로고
    • Rho-associated kinase-dependent contraction of stress fibres and the organization of focal adhesions
    • K. Katoh, Y. Kano, Y. Noda Rho-associated kinase-dependent contraction of stress fibres and the organization of focal adhesions J R Soc Interface 8 2011 305 311
    • (2011) J R Soc Interface , vol.8 , pp. 305-311
    • Katoh, K.1    Kano, Y.2    Noda, Y.3
  • 86
    • 36248969983 scopus 로고    scopus 로고
    • Actin stress fibres
    • S. Pellegrin, H. Mellor Actin stress fibres J Cell Sci 120 2007 3491 3499
    • (2007) J Cell Sci , vol.120 , pp. 3491-3499
    • Pellegrin, S.1    Mellor, H.2
  • 87
    • 77749254700 scopus 로고    scopus 로고
    • Mechanistic basis of Rho GTPase-induced extracellular matrix synthesis in trabecular meshwork cells
    • P.P. Pattabiraman, P.V. Rao Mechanistic basis of Rho GTPase-induced extracellular matrix synthesis in trabecular meshwork cells Am J Physiol Cell Physiol 298 2010 C749 C763
    • (2010) Am J Physiol Cell Physiol , vol.298
    • Pattabiraman, P.P.1    Rao, P.V.2
  • 90
    • 44649105940 scopus 로고    scopus 로고
    • Transgenic mice expressing the Tyr437His mutant of human myocilin protein develop glaucoma
    • Y. Zhou, O. Grinchuk, S.I. Tomarev Transgenic mice expressing the Tyr437His mutant of human myocilin protein develop glaucoma Invest Ophthalmol Vis Sci 49 2008 1932 1939
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 1932-1939
    • Zhou, Y.1    Grinchuk, O.2    Tomarev, S.I.3
  • 92
    • 80054998108 scopus 로고    scopus 로고
    • Ocular hypotensive effect of the rho kinase inhibitor AR-12286 in patients with glaucoma and ocular hypertension
    • R.D. Williams, G.D. Novack, T. Van Haarlem, C. Kopczynski Ocular hypotensive effect of the rho kinase inhibitor AR-12286 in patients with glaucoma and ocular hypertension Am J Ophthalmol 152 2011 834 841
    • (2011) Am J Ophthalmol , vol.152 , pp. 834-841
    • Williams, R.D.1    Novack, G.D.2    Van Haarlem, T.3    Kopczynski, C.4
  • 94
    • 0000723422 scopus 로고
    • Age-related loss of α-smooth muscle actin in normal and glaucomatous human trabecular meshwork of different age groups
    • C. Flügel, E. Tamm, E. Lütjen-Drecoll, F.H. Stefani Age-related loss of α-smooth muscle actin in normal and glaucomatous human trabecular meshwork of different age groups J Glaucoma 1 1992 165 173
    • (1992) J Glaucoma , vol.1 , pp. 165-173
    • Flügel, C.1    Tamm, E.2    Lütjen-Drecoll, E.3    Stefani, F.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.