Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance-associated promotion of Alzheimer's disease β-amyloid neuropathology

FASEB Journal

Volumn 19, Issue 14, 2005, Pages 2081-2082

  Zhao, Zhong ^a   Ho, Lap ^a   Wang, Jun ^a   Qin, Weiping ^a   Festa, Eugene D ^a   Mobbs, Charles ^b   Hof, Patrick ^b   Rocher, Anne ^b   Masur, Sandra ^b,c   Haroutunian, Vahram ^b   Pasinetti, Giulio Maria ^a,b,c,d  

^a Neuroinflammation Research Laboratories   (United States)

^b Department of Psychiatry ^*  (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; CONNECTIVE TISSUE GROWTH FACTOR; GAMMA SECRETASE; HUMAN RECOMBINANT CONNECTIVE TISSUE GROWTH FACTOR; INSULIN; INSULINASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN DISEASE; COGNITIVE DEFECT; DEMENTIA; ENZYME ACTIVITY; GENE EXPRESSION; INSULIN RESISTANCE; MOUSE; NEUROFIBRILLARY TANGLE; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; RISK FACTOR;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMAL FEED; ANIMALS; ASPARTIC ENDOPEPTIDASES; BRAIN; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENDOPEPTIDASES; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROSIS; GENE EXPRESSION REGULATION; GENOME; HUMANS; IMMEDIATE-EARLY PROTEINS; INSULIN; INSULIN RESISTANCE; INSULYSIN; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MODELS, BIOLOGICAL; NEUROFIBRILLARY TANGLES; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEPTIDES; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SENILE PLAQUES; SPECIES SPECIFICITY; TIME FACTORS;

ANIMALIA;

EID: 28744437870     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.05-4359fje     Document Type: Article

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