CCN4 induces IL-6 production through αvβ5 receptor, PI3K, Akt, and NF-κB singling pathway in human synovial fibroblasts

Arthritis Research and Therapy

Volumn 15, Issue 1, 2013, Pages

  Hou, Chun Han ^a   Tang, Chih Hsin ^b,c   Hsu, Chin Jung ^c,d   Hou, Sheng Mon ^e   Liu, Ju Fang ^e  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^e SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHAVBETA5 INTEGRIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; NEUTRALIZING ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG; WNT INDUCIBLE SIGNALING PATHWAY PROTEIN 1; WNT PROTEIN; CCN PROTEIN; IL6 PROTEIN, HUMAN; ONCOPROTEIN; VITRONECTIN RECEPTOR; WISP1 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; INTRACELLULAR SIGNALING; OSTEOARTHRITIS; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; BIOSYNTHESIS; CELL CULTURE; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; SIGNAL TRANSDUCTION; SYNOVIUM;

BLOTTING, WESTERN; CCN INTERCELLULAR SIGNALING PROTEINS; CELLS, CULTURED; FIBROBLASTS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; NF-KAPPA B; OSTEOARTHRITIS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, VITRONECTIN; SIGNAL TRANSDUCTION; SYNOVIAL MEMBRANE; TRANSFECTION;

EID: 84872593277     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar4151     Document Type: Article

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