Curcumin inhibits TGFβ1-induced CCN2 via Src, JNK, and Smad3 in gingiva

Journal of Dental Research

Volumn 92, Issue 7, 2013, Pages 629-634

  Yang, W H ^a   Kuo, M Y P ^a   Liu, C M ^a   Deng, Y T ^a   Chang, H H ^a   Chang, J Z C ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

connective tissue growth factor; CTGF CCN2; curcumin; gingival overgrowth; TGF 1; transforming growth factor

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ANTHRA(1,9 CD)PYRAZOL 6(2H) ONE; ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONE; ANTHRACENE DERIVATIVE; CATECHIN; CONNECTIVE TISSUE GROWTH FACTOR; CTGF PROTEIN, HUMAN; CURCUMIN; DRUG DERIVATIVE; ENZYME INHIBITOR; EPIGALLOCATECHIN GALLATE; FLAVONOID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMIDAZOLE DERIVATIVE; MEVINOLIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; NONSTEROID ANTIINFLAMMATORY AGENT; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; SMAD3 PROTEIN; SMAD3 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CELL CULTURE; CELL MOTION; CTGF/CCN2; CULTURE TECHNIQUE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FIBROBLAST; GINGIVA; GINGIVA OVERGROWTH; HUMAN; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; TGFΒ1; TRANSFORMING GROWTH FACTOR Β;

CONNECTIVE TISSUE GROWTH FACTOR; CTGF/CCN2; CURCUMIN; GINGIVAL OVERGROWTH; TGFΒ1; TRANSFORMING GROWTH FACTOR Β;

ANTHRACENES; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CATECHIN; CELL CULTURE TECHNIQUES; CELL MOVEMENT; CELLS, CULTURED; CONNECTIVE TISSUE GROWTH FACTOR; CURCUMIN; ENZYME INHIBITORS; FIBROBLASTS; FLAVONOIDS; GINGIVA; GINGIVAL OVERGROWTH; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; IMIDAZOLES; LOVASTATIN; MAP KINASE KINASE 4; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PYRIDINES; PYRIMIDINES; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; SRC-FAMILY KINASES; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84879164669     PISSN: 00220345     EISSN: 15440591     Source Type: Journal    
DOI: 10.1177/0022034513488139     Document Type: Article

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