Differential expression of the CCN family members Cyr61, CTGF and Nov in human breast cancer

Endocrine-Related Cancer

Volumn 11, Issue 4, 2004, Pages 781-791

  Jiang, Wen G ^a   Watkins, Gareth ^a   Fodstad, Oystein ^b   Douglas Jones, Anthony ^a   Mokbel, Kefah ^c   Mansel, Robert E ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF SOUTH ALABAMA   (United States)

^c ST GEORGE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CONNECTIVE TISSUE GROWTH FACTOR; CYSTEINE RICH PROTEIN 61; MESSENGER RNA; NEPHROBLASTOMA OVEREXPRESSED PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER GROWTH; CANCER INHIBITION; CANCER INVASION; CANCER MORTALITY; CANCER RECURRENCE; CANCER SURVIVAL; CARCINOGENESIS; CELL ADHESION; CELL GROWTH; CELL MIGRATION; CELL STRAIN MCF 7; CELL TYPE; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA SEQUENCE; ENDOTHELIUM CELL; FIBROBLAST; FROZEN SECTION; GENE EXPRESSION; HORMONAL REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; METASTASIS POTENTIAL; NUCLEOTIDE SEQUENCE; OUTCOMES RESEARCH; POLYMERASE CHAIN REACTION; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; TISSUE LEVEL;

BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMEDIATE-EARLY PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; NEOPLASM STAGING; PROGNOSIS; RECEPTORS, ESTROGEN; RNA, MESSENGER; RNA, NEOPLASM; SURVIVAL ANALYSIS;

EID: 11244333091     PISSN: 13510088     EISSN: None     Source Type: Journal    
DOI: 10.1677/erc.1.00825     Document Type: Article

References (35)

1. Babic AM, Kireeva ML, Kolesnikova TV & Lau LF 1998 CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth. PNAS 95 6355-6360.
2. Brigstock DR 2003 The CCN family, a new stimulus package. Journal of Endocrinology 178 169-175.
3. Davies G, Jiang WG & Mason MD 2000 Cell-cell adhesion and signalling intermediates in human prostate cancer. Journal of Urology 163 985-992.
4. Gupta N, Wang H, McLeod TL, Naus CC, Kyurkchiev S, Advani S, Yu J, Perbal B & Weichselbaum RR 2001 Inhibition of glioma cell growth and tumorigenic potential by CCN3 (NOV). Molecular Pathology 54 293-299.
5. Hishikawa K, Oemar BS, Tanner FC, Nakaki T, Luscher TF & Fujii T 1999 Connective tissue growth factor induces apoptosis in human breast cancer cell line MCF-7. Journal of Biological Chemistry 274 37461-37466.
6. Jiang WG, Watkins G, Lane J, Douglas-Jones A, Cunnick GH, Mokbel M & Mansel RE 2003a Prognostic value of Rho familty and and rho-GDIs in breast cancer. Clinical Cancer Research 9 6432-6440.
7. Jiang WG, Douglas-Jones A & Mansel RE 2003b Level of expression of PPAR-gamma and its co-activator (PPAR-GCA) in human breast cancer. International Journal of Cancer 106 752-757.
8. Jiang WG, Grimshaw D, Lane J, Martin TA, Parr C, Davies G, Laterra J & Mansel RE 2003c Retroviral hammerhead transgenes to cMET and HGF/SF inhibited growth of breast tumour, induced by fibroblasts. Clinical Cancer Research 9 4274-4281.
9. Jiang WG, Watkins G, Douglas-Jones A & Mansel RE 2004 Psoriasin (S100A7) is aberrantly expressed in human breast cancer and is related to clinical outcomes. International Journal of Oncology 25 81-86.
10. King JAC, Ofori-Acquah AF, Stevens T, Al-Mehdi AB, Fodstad O & Jiang WG 2004 Prognostic value of ALCAM in human breast cancer. Breast Cancer Research 6 R478-R487.
11. Koliopanos A, Friess H, di Mola FF, Tang WH, Kubulus D, Brigstock D, Zimmermann A & Buchler MW 2002 Connective tissue growth factor gene expression alters tumor progression in esophageal cancer. World Journal of Surgery 26 420-427.
12. Kothapalli D & Grotendorst GR 2000 CTGF modulates cell cycle progression in cAMP-arrested NRK fibroblasts. Journal of Cellular Physiology 182 119-126.
13. Leu SJ, Lam SC & Lau LF 2002 Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells. Journal of Biological Chemistry 277 46248-46255.
14. Liu C, Liu XJ, Crowe PD, Kelner GS, Fan J, Barry G, Manu F, Ling N, De Souza EB & Maki RA 1999 Nephroblastoma overexpressed gene (NOV) codes for a growth factor that induces protein tyrosine phosphorylation. Gene 238 471-478.
15. Manara MC, Perbal B, Benini S, Strammiello R, Cerisano V, Perdichizzi S, Serra M, Astolfi A, Bertoni F, Alami J, et al. 2002 The expression of ccn3(nov) gene in musculoskeletal tumors. American Journal of Pathology 160 849-859.
16. Martinerie C, Gicquel C, Louvel A, Laurent M, Schofield PN & Le Bouc Y 2001 Altered expression of novH is associated with human adrenocortical tumorigenesis. Journal of Clinical Endocrinology and Metabolism 86 3929-3940.
17. Mo FE, Muntean AG, Chen CC, Stolz DB, Watkins SC & Lau LF 2002 CYR61 (CCN1) is essential for placental development and vascular integrity. Molecular and Cellular Biology 22 8709-8720.
18. Moritani NH, Kubota S, Nishida T, Kawaki H, Kondo S, Sugahara T & Takigawa M 2003 Suppressive effect of overexpressed connective tissue growth factor on tumor cell growth in a human oral squamous cell carcinoma-derived cell line. Cancer Letters 192 205-214.
19. Nazarenko IA, Bhatnagar SK & Hohman RJ 1997 A closed tube format for amplification and detection of DNA based on energy transfer. Nucleic Acids Research 25 2516-2521.
20. Pan LH, Beppu T, Kurose A, Yamauchi K, Sugawara A, Suzuki M, Ogawa A & Sawai T 2002 Neoplastic cells and proliferating endothelial cells express connective tissue growth factor (CTGF) in glioblastoma. Neurology Research 24 677-683.
21. Parr C & Jiang WG 2004 The Notch receptors, Notch-1 and Notch-2, in human breast cancers. International Journal of Molecular Medicine (In Press).
22. Perbel B 2004 CCN proteins: multifunctional signalling regulators. Lancet 363 62-64.
23. Pilarsky CP, Schmidt U, Eissrich C, Stade J, Froschermaier SE, Haase M, Faller G, Kirchner TW & Wirth MP 1998 Expression of the extracellular matrix signaling molecule Cyr61 is downregulated in prostate cancer. Prostate 36 85-91.
24. Sampath D, Winneker RC & Zhang Z 2001 Cyr61, a member of the CCN family, is required for MCF-7 cell proliferation: regulation by 17beta-estradiol and overexpression in human breast cancer. Endocrinology 142 2540-2548.
25. Sampath D, Winneker RC & Zhang Z 2002 The angiogenic factor Cyr61 is induced by the progestin R5020 and is necessary for mammary adenocarcinoma cell growth. Endocrine 18 147-159.
26. Stanhope-Baker P & Williams BR 2000 Identification of connective tissue growth factor as a target of WT1 transcriptional regulation. Journal of Biological Chemistry 275 38139-38150.
27. Tong X, Xie D, O'Kelly J, Miller CW, Muller-Tidow C & Koeffler HP 2001 Cyr61, a member of CCN family, is a tumor suppressor in non-small cell lung cancer. Journal of Biological Chemistry 276 47709-47714.
28. Tsai MS, Hornby AE, Lakins J, Lupu R 2000 Expression and function of CYR61, an angiogenic factor, in breast cancer cell lines and tumor biopsies. Cancer Research 60 5603-5607.
29. Tsai MS, Bogart DF, Castaneda JM, Li P & Lupu R 2002a Cyr61 promotes breast tumorigenesis and cancer progression. Oncogene 21 8178-8185.
30. Tsai MS, Bogart DF, Li P, Mehmi I, Lupu R 2002b Expression and regulation of Cyr61 in human breast cancer cell lines. Oncogens 21 964-973.
31. Wasenius VM, Hemmer S, Kettunen E, Knuutila S, Franssila K & Joensuu H 2003 Hepatocyte growth factor receptor, matrix metalloproteinase-11, tissue inhibitor of metalloproteinase-1, and fibronectin are up-regulated in papillary thyroid carcinoma: a cDNA and tissue microarray study. Clinical Cancer Research 9 68-75.
32. Wenger C, Ellenrieder V, Alber B, Lacher U, Menke A, Hameister H, Wilda M, Iwamura T, Beger HG, Adler G, Gress TM 1999 Expression and differential regulation of connective tissue growth factor in pancreatic cancer cells. Oncogene 18 1073-1080.
33. Xie D, Nakachi K, Wang H, Elashoff R & Koeffler HP 2001a Elevated levels of connective tissue growth factor, WISP-1, and CYR61 in primary breast cancers associated with more advanced features. Cancer Research 61 8917-8923.
34. Xie D, Miller CW, O'Kelly J, Nakachi K, Sakashita A, Said JW, Gornbein J & Koeffler HP 2001b Breast cancer. Cyr61 is overexpressed, estrogen-inducible, and associated with more advanced disease. Journal of Biological Chemistry 276 14187-14194.
35. Ye L, Martin TA, Parr C, Harrison G, Mansel RE & Jiang WG 2003 Biphasic effects of 17-β-oestradiol on expression of occludin and transendothelial resistance (TER) and paracellular permeability in human vascular endothelial cells. Journal of Cellular Physiology 196 362-369.