Hyperglycemia causes renal cell damage via CCN2-induced activation of the TrkA receptor: Implications for diabetic nephropathy

Diabetes

Volumn 61, Issue 9, 2012, Pages 2280-2288

  Fragiadaki, Maria ^a   Hill, Nicola ^a   Hewitt, Reiko ^a   Bou Gharios, George ^a   Cook, Terence ^a   Tam, Frederick W ^a   Domin, Jan ^a,b   Mason, Roger M ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF BEDFORDSHIRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXYGEN; PROTEIN TYROSINE KINASE A; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SNAIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DIABETIC NEPHROPATHY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERGLYCEMIA; HYPOXIA; KIDNEY CELL; KIDNEY DISEASE; KIDNEY FAILURE; KIDNEY INJURY; MESANGIUM CELL; MOUSE; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RENAL CELL DAMAGE;

ANIMALS; ANOXIA; CONNECTIVE TISSUE GROWTH FACTOR; DIABETIC NEPHROPATHIES; HUMANS; HYPERGLYCEMIA; KIDNEY; MAP KINASE SIGNALING SYSTEM; MESANGIAL CELLS; MICE; PHOSPHORYLATION; RECEPTOR, TRKA; REPERFUSION INJURY; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84865492920     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-1138     Document Type: Article

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