Genome engineering at the Dawn of the golden age

Annual Review of Genomics and Human Genetics

Volumn 14, Issue , 2013, Pages 135-158

  Segal, David J ^a   Meckler, Joshua F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Animal models; Gene targeting; Meganuclease; TALEN; Targeted mutagenesis; Transcription activator like effector nuclease; ZFN; Zinc finger nuclease

Indexed keywords

DNA FRAGMENT; GUIDE RNA; NUCLEASE; THYMIDINE KINASE; ZINC FINGER NUCLEASE; ZINC FINGER PROTEIN;

DNA BINDING MOTIF; DNA CLEAVAGE; DNA END JOINING REPAIR; DNA MODIFICATION; DNA SEQUENCE; DNA TRANSFECTION; DOUBLE STRANDED DNA BREAK; EMBRYONIC STEM CELL; FRAMESHIFT MUTATION; GENE TARGETING; GENETIC ENGINEERING; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN GENETICS; HUMAN GENOME; INDEL MUTATION; MUTAGENESIS; MUTATION; NONHUMAN; PLURIPOTENT STEM CELL; POINT MUTATION; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; GENE TARGETING; GENETIC ENGINEERING; GENETIC THERAPY; GENOME; GENOME, HUMAN; HUMANS; MICE;

EID: 84884325112     PISSN: 15278204     EISSN: 1545293X     Source Type: Book Series    
DOI: 10.1146/annurev-genom-091212-153435     Document Type: Review

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