Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases

Nucleic Acids Research

Volumn 40, Issue 13, 2012, Pages 6367-6379

  Daboussi, Fayza ^a   Zaslavskiy, Mikhail ^a   Poirot, Laurent ^a   Loperfido, Mariana ^b,c   Gouble, Agnès ^a   Guyot, Valerie ^a   Leduc, Sophie ^a   Galetto, Roman ^a   Grizot, Sylvestre ^a   Oficjalska, Danusia ^a   Perez, Christophe ^a   Delacôte, Fabien ^a   Dupuy, Aurélie ^a,e   Chion Sotinel, Isabelle ^a   Le Clerre, Diane ^a   Lebuhotel, Céline ^a   Danos, Olivier ^d   Lemaire, Frédéric ^a   Oussedik, Kahina ^a   Cédrone, Frédéric ^a   Epinat, Jean Charles ^a   Smith, Julianne ^a   Yáñez Muñoz, Rafael J ^f   Dickson, George ^f   Popplewell, Linda ^f   Koo, Taeyoung ^f   Vandendriessche, Thierry ^b,c   Chuah, Marinee K ^b,c   Duclert, Aymeric ^a   Duchateau, Philippe ^a   Pâques, Frédéric ^a   more..

^a 8 rue de la Croix Jarry   (France)

^b FREE UNIVERSITY OF BRUSSELS   (Belgium)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d INSERM   (France)

^e INSTITUT GUSTAVE ROUSSY   (France)

^f UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE;

ANIMAL CELL; ARTICLE; CHROMOSOME; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME SUBSTRATE; EPIGENETICS; GENE LOCUS; GENE TARGETING; GENETIC ENGINEERING; HUMAN; HUMAN CELL; MUTAGENESIS; NONHUMAN; PREDICTION; PRIORITY JOURNAL;

ANIMALS; CELL LINE; CHO CELLS; CHROMOSOMAL POSITION EFFECTS; CRICETINAE; CRICETULUS; DNA RESTRICTION ENZYMES; GENE TARGETING; GENETIC ENGINEERING; GENOME, HUMAN; HUMANS; MUTAGENESIS;

EID: 84862745388     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks268     Document Type: Article

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