Highly efficient generation of heritable zebrafish gene mutations using homo-and heterodimeric TALENs

Nucleic Acids Research

Volumn 40, Issue 16, 2012, Pages 8001-8010

  Cade, Lindsay ^a   Reyon, Deepak ^a,b,c   Hwang, Woong Y ^a   Tsai, Shengdar Q ^a,b,c   Patel, Samir ^a   Khayter, Cyd ^a,b   Joung, J Keith ^a,b,c   Sander, Jeffry D ^a,b,c   Peterson, Randall T ^a,d   Yeh, Jing Ruey Joanna ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Center for Cancer Research   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HETERODIMER TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; HOMODIMER TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; MESSENGER RNA; NUCLEASE; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; GENE DISRUPTION; GENE INACTIVATION; GENE MUTATION; GENE SEQUENCE; GENE TARGETING; GENETIC ANALYSIS; GERM LINE; HEREDITY; INDEL MUTATION; MUTAGENESIS; MUTATION RATE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOMATIC MUTATION; ZEBRA FISH;

ALLELES; ANIMALS; BASE SEQUENCE; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DIMERIZATION; DNA-BINDING PROTEINS; GENE KNOCKOUT TECHNIQUES; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; TRANS-ACTIVATORS; ZEBRAFISH;

DANIO RERIO;

EID: 84866072998     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks518     Document Type: Article

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