-
1
-
-
77956126894
-
Xanthomonas AvrBs3 family-type III effectors: discovery and function
-
Boch J, Bonas U (2010) Xanthomonas AvrBs3 family-type III effectors: discovery and function. Annu Rev Phytopathol 48: 419-436.
-
(2010)
Annu Rev Phytopathol
, vol.48
, pp. 419-436
-
-
Boch, J.1
Bonas, U.2
-
2
-
-
72149110399
-
Breaking the code of DNA binding specificity of TAL-type III effectors
-
Boch J, Scholze H, Schornack S, Landgraf A, Hahn S, Kay S, Lahaye T, Nickstadt A, Bonas U (2009) Breaking the code of DNA binding specificity of TAL-type III effectors. Science 326: 1509-1512.
-
(2009)
Science
, vol.326
, pp. 1509-1512
-
-
Boch, J.1
Scholze, H.2
Schornack, S.3
Landgraf, A.4
Hahn, S.5
Kay, S.6
Lahaye, T.7
Nickstadt, A.8
Bonas, U.9
-
4
-
-
0024690540
-
Genetic and structural characterization of the avirulence gene AvrBs3 from Xanthomonas campestris pv. vesicatoria
-
Bonas U, Stall RE, Staskawicz B (1989) Genetic and structural characterization of the avirulence gene AvrBs3 from Xanthomonas campestris pv. vesicatoria. Mol Gen Genet 218: 127-136.
-
(1989)
Mol Gen Genet
, vol.218
, pp. 127-136
-
-
Bonas, U.1
Stall, R.E.2
Staskawicz, B.3
-
5
-
-
0027264020
-
Resistance in tomato to Xanthomonas campestris pv vesicatoria is determined by alleles of the pepper-specific avirulence gene avrBs3
-
Bonas U, Conrads-Strauch J, Balbo I (1993) Resistance in tomato to Xanthomonas campestris pv vesicatoria is determined by alleles of the pepper-specific avirulence gene avrBs3. Mol Gen Genet 238: 261-269.
-
(1993)
Mol Gen Genet
, vol.238
, pp. 261-269
-
-
Bonas, U.1
Conrads-Strauch, J.2
Balbo, I.3
-
6
-
-
61649085865
-
Targeted transgene integration in plant cells using designed zinc finger nucleases
-
Cai CQ, Doyon Y, Ainley WM, Miller JC, Dekelver RC, Moehle EA, Rock JM, Lee YL, Garrison R, Schulenberg L et al (2009) Targeted transgene integration in plant cells using designed zinc finger nucleases. Plant Mol Biol 69: 699-709.
-
(2009)
Plant Mol Biol
, vol.69
, pp. 699-709
-
-
Cai, C.Q.1
Doyon, Y.2
Ainley, W.M.3
Miller, J.C.4
Dekelver, R.C.5
Moehle, E.A.6
Rock, J.M.7
Lee, Y.L.8
Garrison, R.9
Schulenberg, L.10
-
7
-
-
79960064013
-
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
-
Cermak T, Doyle EL, Christian M, Wang L, Zhang Y, Schmidt C, Baller JA, Somia NV, Bogdanove AJ, Voytas DF (2011) Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting. Nucleic Acids Res 39: e82.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Cermak, T.1
Doyle, E.L.2
Christian, M.3
Wang, L.4
Zhang, Y.5
Schmidt, C.6
Baller, J.A.7
Somia, N.V.8
Bogdanove, A.J.9
Voytas, D.F.10
-
8
-
-
78951479577
-
Targeting DNA double-strand breaks with TAL effector nucleases
-
Christian M, Cermak T, Doyle EL, Schmidt C, Zhang F, Hummel A, Bogdanove AJ, Voytas DF (2010) Targeting DNA double-strand breaks with TAL effector nucleases. Genetics 186: 757-761.
-
(2010)
Genetics
, vol.186
, pp. 757-761
-
-
Christian, M.1
Cermak, T.2
Doyle, E.L.3
Schmidt, C.4
Zhang, F.5
Hummel, A.6
Bogdanove, A.J.7
Voytas, D.F.8
-
9
-
-
44949155482
-
Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases
-
Doyon Y, McCammon JM, Miller JC, Faraji F, Ngo C, Katibah GE, Amora R, Hocking TD, Zhang L, Rebar EJ et al (2008) Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases. Nat Biotechnol 26: 702-708.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 702-708
-
-
Doyon, Y.1
McCammon, J.M.2
Miller, J.C.3
Faraji, F.4
Ngo, C.5
Katibah, G.E.6
Amora, R.7
Hocking, T.D.8
Zhang, L.9
Rebar, E.J.10
-
10
-
-
27744530147
-
Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells
-
Durai S, Mani M, Kandavelou K, Wu J, Porteus MH, Chandrasegaran S (2005) Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells. Nucleic Acids Res 33: 5978-5990.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 5978-5990
-
-
Durai, S.1
Mani, M.2
Kandavelou, K.3
Wu, J.4
Porteus, M.H.5
Chandrasegaran, S.6
-
12
-
-
79956261977
-
Transcriptional activators of human genes with programmable DNA-specificity
-
Geissler R, Scholze H, Hahn S, Streubel J, Bonas U, Behrens SE, Boch J (2011) Transcriptional activators of human genes with programmable DNA-specificity. PLoS One 6: e19509.
-
(2011)
PLoS One
, vol.6
-
-
Geissler, R.1
Scholze, H.2
Hahn, S.3
Streubel, J.4
Bonas, U.5
Behrens, S.E.6
Boch, J.7
-
13
-
-
79961185942
-
Heritable gene targeting in zebrafish using customized TALENs
-
Huang P, Xiao A, Zhou M, Zhu Z, Lin S, Zhang B (2011) Heritable gene targeting in zebrafish using customized TALENs. Nat Biotechnol 29: 699-700.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 699-700
-
-
Huang, P.1
Xiao, A.2
Zhou, M.3
Zhu, Z.4
Lin, S.5
Zhang, B.6
-
14
-
-
69049104003
-
Targeted manipulation of mammalian genomes using designed zinc finger nucleases
-
Kandavelou K, Ramalingam S, London V, Mani M, Wu J, Alexeev V, Civin CI, Chandrasegaran S (2009) Targeted manipulation of mammalian genomes using designed zinc finger nucleases. Biochem Biophys Res Commun 388: 56-61.
-
(2009)
Biochem Biophys Res Commun
, vol.388
, pp. 56-61
-
-
Kandavelou, K.1
Ramalingam, S.2
London, V.3
Mani, M.4
Wu, J.5
Alexeev, V.6
Civin, C.I.7
Chandrasegaran, S.8
-
15
-
-
78651270582
-
TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain
-
Li T, Huang S, Jiang WZ, Wright D, Spalding MH, Weeks DP, Yang B (2011a) TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain. Nucleic Acids Res 39: 359-372.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 359-372
-
-
Li, T.1
Huang, S.2
Jiang, W.Z.3
Wright, D.4
Spalding, M.H.5
Weeks, D.P.6
Yang, B.7
-
16
-
-
79960034141
-
Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes
-
Li T, Huang S, Zhao X, Wright DA, Carpenter S, Spalding MH, Weeks DP, Yang B (2011b) Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes. Nucleic Acids Res 39: 6315-6325.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 6315-6325
-
-
Li, T.1
Huang, S.2
Zhao, X.3
Wright, D.A.4
Carpenter, S.5
Spalding, M.H.6
Weeks, D.P.7
Yang, B.8
-
17
-
-
77956975564
-
RNA-directed DNA methylation: mechanisms and functions
-
Mahfouz MM (2010) RNA-directed DNA methylation: mechanisms and functions. Plant Signal Behav 5: 806-816.
-
(2010)
Plant Signal Behav
, vol.5
, pp. 806-816
-
-
Mahfouz, M.M.1
-
18
-
-
84863174983
-
TALE nucleases and next generation GM crops
-
Mahfouz MM, Li L (2011) TALE nucleases and next generation GM crops. GM Crop 2: 1236-1256.
-
(2011)
GM Crop
, vol.2
, pp. 1236-1256
-
-
Mahfouz, M.M.1
Li, L.2
-
19
-
-
84855882014
-
Targeted transcriptional repression using a chimeric TALE-SRDX repressor protein
-
doi: 10. 1007/s11103-011-9866-x
-
Mahfouz MM, Li L, Piatek M, Fang X, Mansour H, Bangarusamy D, Zhu J-K (2011a) Targeted transcriptional repression using a chimeric TALE-SRDX repressor protein. Plant Mol Biol. doi: 10. 1007/s11103-011-9866-x.
-
(2011)
Plant Mol Biol
-
-
Mahfouz, M.M.1
Li, L.2
Piatek, M.3
Fang, X.4
Mansour, H.5
Bangarusamy, D.6
Zhu, J.-K.7
-
20
-
-
79952302385
-
De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks
-
Mahfouz MM, Li L, Shamimuzzaman M, Wibowo A, Fang X, Zhu JK (2011b) De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks. Proc Natl Acad Sci USA 108: 2623-2628.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 2623-2628
-
-
Mahfouz, M.M.1
Li, L.2
Shamimuzzaman, M.3
Wibowo, A.4
Fang, X.5
Zhu, J.K.6
-
21
-
-
23044460704
-
Binding of two zinc finger nuclease monomers to two specific sites is required for effective double-strand DNA cleavage
-
Mani M, Smith J, Kandavelou K, Berg JM, Chandrasegaran S (2005) Binding of two zinc finger nuclease monomers to two specific sites is required for effective double-strand DNA cleavage. Biochem Biophys Res Commun 334: 1191-1197.
-
(2005)
Biochem Biophys Res Commun
, vol.334
, pp. 1191-1197
-
-
Mani, M.1
Smith, J.2
Kandavelou, K.3
Berg, J.M.4
Chandrasegaran, S.5
-
22
-
-
34447319080
-
An improved zinc-finger nuclease architecture for highly specific genome editing
-
Miller JC, Holmes MC, Wang J, Guschin DY, Lee YL, Rupniewski I, Beausejour CM, Waite AJ, Wang NS, Kim KA et al (2007) An improved zinc-finger nuclease architecture for highly specific genome editing. Nat Biotechnol 25: 778-785.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 778-785
-
-
Miller, J.C.1
Holmes, M.C.2
Wang, J.3
Guschin, D.Y.4
Lee, Y.L.5
Rupniewski, I.6
Beausejour, C.M.7
Waite, A.J.8
Wang, N.S.9
Kim, K.A.10
-
23
-
-
79551685675
-
A TALE nuclease architecture for efficient genome editing
-
Miller JC, Tan S, Qiao G, Barlow KA, Wang J, Xia DF, Meng X, Paschon DE, Leung E, Hinkley SJ et al (2011) A TALE nuclease architecture for efficient genome editing. Nat Biotechnol 29: 143-148.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 143-148
-
-
Miller, J.C.1
Tan, S.2
Qiao, G.3
Barlow, K.A.4
Wang, J.5
Xia, D.F.6
Meng, X.7
Paschon, D.E.8
Leung, E.9
Hinkley, S.J.10
-
24
-
-
78650739853
-
Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors
-
Morbitzer R, Romer P, Boch J, Lahaye T (2010) Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors. Proc Natl Acad Sci USA 107: 21617-21622.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 21617-21622
-
-
Morbitzer, R.1
Romer, P.2
Boch, J.3
Lahaye, T.4
-
26
-
-
72149090954
-
A simple cipher governs DNA recognition by TAL effectors
-
Moscou MJ, Bogdanove AJ (2009) A simple cipher governs DNA recognition by TAL effectors. Science 326: 1501.
-
(2009)
Science
, vol.326
, pp. 1501
-
-
Moscou, M.J.1
Bogdanove, A.J.2
-
27
-
-
80053039555
-
A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
-
Mussolino C, Morbitzer R, Lutge F, Dannemann N, Lahaye T, Cathomen T (2011) A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity. Nucleic Acids Res 39(21): 9283-9293.
-
(2011)
Nucleic Acids Res
, vol.39
, Issue.21
, pp. 9283-9293
-
-
Mussolino, C.1
Morbitzer, R.2
Lutge, F.3
Dannemann, N.4
Lahaye, T.5
Cathomen, T.6
-
28
-
-
84934444085
-
Design and testing of zinc finger nucleases for use in mammalian cells
-
Porteus M (2008) Design and testing of zinc finger nucleases for use in mammalian cells. Methods Mol Biol 435: 47-61.
-
(2008)
Methods Mol Biol
, vol.435
, pp. 47-61
-
-
Porteus, M.1
-
29
-
-
61449266636
-
Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels
-
Pruett-Miller SM, Reading DW, Porter SN, Porteus MH (2009) Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels. PLoS Genet 5: e1000376.
-
(2009)
PLoS Genet
, vol.5
-
-
Pruett-Miller, S.M.1
Reading, D.W.2
Porter, S.N.3
Porteus, M.H.4
-
30
-
-
42949083192
-
Unexpected failure rates for modular assembly of engineered zinc fingers
-
Ramirez CL, Foley JE, Wright DA, Muller-Lerch F, Rahman SH, Cornu TI, Winfrey RJ, Sander JD, Fu F, Townsend JA et al (2008) Unexpected failure rates for modular assembly of engineered zinc fingers. Nat Methods 5: 374-375.
-
(2008)
Nat Methods
, vol.5
, pp. 374-375
-
-
Ramirez, C.L.1
Foley, J.E.2
Wright, D.A.3
Muller-Lerch, F.4
Rahman, S.H.5
Cornu, T.I.6
Winfrey, R.J.7
Sander, J.D.8
Fu, F.9
Townsend, J.A.10
-
31
-
-
73949106226
-
A single plant resistance gene promoter engineered to recognize multiple TAL effectors from disparate pathogens
-
Romer P, Recht S, Lahaye T (2009) A single plant resistance gene promoter engineered to recognize multiple TAL effectors from disparate pathogens. Proc Natl Acad Sci USA 106: 20526-20531.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 20526-20531
-
-
Romer, P.1
Recht, S.2
Lahaye, T.3
-
32
-
-
77955737033
-
Promoter elements of rice susceptibility genes are bound and activated by specific TAL effectors from the bacterial blight pathogen, Xanthomonas oryzae pv. oryzae
-
Romer P, Recht S, Strauss T, Elsaesser J, Schornack S, Boch J, Wang S, Lahaye T (2010) Promoter elements of rice susceptibility genes are bound and activated by specific TAL effectors from the bacterial blight pathogen, Xanthomonas oryzae pv. oryzae. New Phytol 187: 1048-1057.
-
(2010)
New Phytol
, vol.187
, pp. 1048-1057
-
-
Romer, P.1
Recht, S.2
Strauss, T.3
Elsaesser, J.4
Schornack, S.5
Boch, J.6
Wang, S.7
Lahaye, T.8
-
33
-
-
34547605763
-
Zinc finger targeter (ZiFiT): an engineered zinc finger/target site design tool
-
Sander JD, Zaback P, Joung JK, Voytas DF, Dobbs D (2007) Zinc finger targeter (ZiFiT): an engineered zinc finger/target site design tool. Nucleic Acids Res 35: W599-W605.
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Sander, J.D.1
Zaback, P.2
Joung, J.K.3
Voytas, D.F.4
Dobbs, D.5
-
34
-
-
77954295352
-
ZiFiT (zinc finger targeter): an updated zinc finger engineering tool
-
Sander JD, Maeder ML, Reyon D, Voytas DF, Joung JK, Dobbs D (2010) ZiFiT (zinc finger targeter): an updated zinc finger engineering tool. Nucleic Acids Res 38: W462-W468.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Sander, J.D.1
Maeder, M.L.2
Reyon, D.3
Voytas, D.F.4
Joung, J.K.5
Dobbs, D.6
-
35
-
-
79961192836
-
Targeted gene disruption in somatic zebrafish cells using engineered TALENs
-
Sander JD, Cade L, Khayter C, Reyon D, Peterson RT, Joung JK, Yeh JR (2011) Targeted gene disruption in somatic zebrafish cells using engineered TALENs. Nat Biotechnol 29: 697-698.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 697-698
-
-
Sander, J.D.1
Cade, L.2
Khayter, C.3
Reyon, D.4
Peterson, R.T.5
Joung, J.K.6
Yeh, J.R.7
-
36
-
-
79551687772
-
TAL effectors are remote controls for gene activation
-
Scholze H, Boch J (2011) TAL effectors are remote controls for gene activation. Curr Opin Microbiol 14: 47-53.
-
(2011)
Curr Opin Microbiol
, vol.14
, pp. 47-53
-
-
Scholze, H.1
Boch, J.2
-
37
-
-
79961196358
-
Knockout rats generated by embryo microinjection of TALENs
-
Tesson L, Usal C, Menoret S, Leung E, Niles BJ, Remy S, Santiago Y, Vincent AI, Meng X, Zhang L et al (2011) Knockout rats generated by embryo microinjection of TALENs. Nat Biotechnol 29: 695-696.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 695-696
-
-
Tesson, L.1
Usal, C.2
Menoret, S.3
Leung, E.4
Niles, B.J.5
Remy, S.6
Santiago, Y.7
Vincent, A.I.8
Meng, X.9
Zhang, L.10
-
38
-
-
79956280633
-
Assembly of designer TAL effectors by golden gate cloning
-
Weber E, Gruetzner R, Werner S, Engler C, Marillonnet S (2011) Assembly of designer TAL effectors by golden gate cloning. PLoS One 6: e19722.
-
(2011)
PLoS One
, vol.6
-
-
Weber, E.1
Gruetzner, R.2
Werner, S.3
Engler, C.4
Marillonnet, S.5
-
39
-
-
77953285393
-
Genome editing in plant cells by zinc finger nucleases
-
Weinthal D, Tovkach A, Zeevi V, Tzfira T (2010) Genome editing in plant cells by zinc finger nucleases. Trends Plant Sci 15(6): 308-321.
-
(2010)
Trends Plant Sci
, vol.15
, Issue.6
, pp. 308-321
-
-
Weinthal, D.1
Tovkach, A.2
Zeevi, V.3
Tzfira, T.4
-
40
-
-
79960558872
-
Targeted genome editing across species using ZFNs and TALENs
-
Wood AJ, Lo TW, Zeitler B, Pickle CS, Ralston EJ, Lee AH, Amora R, Miller JC, Leung E, Meng X et al (2011) Targeted genome editing across species using ZFNs and TALENs. Science 333: 307.
-
(2011)
Science
, vol.333
, pp. 307
-
-
Wood, A.J.1
Lo, T.W.2
Zeitler, B.3
Pickle, C.S.4
Ralston, E.J.5
Lee, A.H.6
Amora, R.7
Miller, J.C.8
Leung, E.9
Meng, X.10
-
41
-
-
77955395799
-
High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases
-
Zhang F, Maeder ML, Unger-Wallace E, Hoshaw JP, Reyon D, Christian M, Li X, Pierick CJ, Dobbs D, Peterson T et al (2010) High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases. Proc Natl Acad Sci USA 107: 12028-12033.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 12028-12033
-
-
Zhang, F.1
Maeder, M.L.2
Unger-Wallace, E.3
Hoshaw, J.P.4
Reyon, D.5
Christian, M.6
Li, X.7
Pierick, C.J.8
Dobbs, D.9
Peterson, T.10
-
42
-
-
79751487297
-
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription
-
Zhang F, Cong L, Lodato S, Kosuri S, Church GM, Arlotta P (2011) Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription. Nat Biotechnol 29: 149-153.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 149-153
-
-
Zhang, F.1
Cong, L.2
Lodato, S.3
Kosuri, S.4
Church, G.M.5
Arlotta, P.6
|