-
2
-
-
0037354165
-
Oxidative stress-mediated hepatotoxicity of iron and copper: role of kupffer cells
-
Videla LA, Fernandez V, Tapia G, Varela P. Oxidative stress-mediated hepatotoxicity of iron and copper: role of kupffer cells. Biometals. 2003;16:103-11.
-
(2003)
Biometals.
, vol.16
, pp. 103-111
-
-
Videla, L.A.1
Fernandez, V.2
Tapia, G.3
Varela, P.4
-
3
-
-
0034869459
-
Oxidative stress-related molecules and liver fibrosis
-
Parola M, Robino G. Oxidative stress-related molecules and liver fibrosis. J Hepatol. 2001;35:297-306.
-
(2001)
J Hepatol.
, vol.35
, pp. 297-306
-
-
Parola, M.1
Robino, G.2
-
4
-
-
0042384686
-
Iron-induced oxidant stress in alcoholic liver fibrogenesis
-
Pietrangelo A. Iron-induced oxidant stress in alcoholic liver fibrogenesis. Alcohol. 2003;30:121-9.
-
(2003)
Alcohol.
, vol.30
, pp. 121-129
-
-
Pietrangelo, A.1
-
5
-
-
1542376929
-
Glutathione metabolism and its implications for health
-
Wu G, Fang Y-Z, Yang S, Lupton JR, Turner ND. Glutathione metabolism and its implications for health. J Nutr. 2004;134:489-92.
-
(2004)
J Nutr.
, vol.134
, pp. 489-492
-
-
Wu, G.1
Fang, Y.-Z.2
Yang, S.3
Lupton, J.R.4
Turner, N.D.5
-
6
-
-
0025987977
-
Oxidative stress: from basic research to clinical application
-
Sies H. Oxidative stress: from basic research to clinical application. Am J Med. 1991;91:31S-8S.
-
(1991)
Am J Med.
, vol.91
, pp. 31S-38S
-
-
Sies, H.1
-
8
-
-
0025157647
-
The pathology of hepatic iron overload: a free radical-mediated process?
-
Bacon BR, Britton RS. The pathology of hepatic iron overload: a free radical-mediated process? Hepatology. 1990;11:127-37.
-
(1990)
Hepatology.
, vol.11
, pp. 127-137
-
-
Bacon, B.R.1
Britton, R.S.2
-
9
-
-
28444454447
-
Hepatotoxicity of iron overload: mechanisms of iron-induced hepatic fibrogenesis
-
Ramm GA, Ruddell RG. Hepatotoxicity of iron overload: mechanisms of iron-induced hepatic fibrogenesis. Semin Liver Dis. 2005;25:433-49.
-
(2005)
Semin Liver Dis.
, vol.25
, pp. 433-449
-
-
Ramm, G.A.1
Ruddell, R.G.2
-
10
-
-
0028099774
-
Morphologic observations in iron overload: an update
-
Iancu TC, Shiloh H. Morphologic observations in iron overload: an update. Adv Exp Med Biol. 1994;356:255-65.
-
(1994)
Adv Exp Med Biol.
, vol.356
, pp. 255-265
-
-
Iancu, T.C.1
Shiloh, H.2
-
11
-
-
41049114693
-
Lysosomes in iron metabolism, ageing and apoptosis
-
Kurz T, Terman A, Gustafsson B, Brunk UT. Lysosomes in iron metabolism, ageing and apoptosis. Histochem Cell Biol. 2008;129:389-406.
-
(2008)
Histochem Cell Biol.
, vol.129
, pp. 389-406
-
-
Kurz, T.1
Terman, A.2
Gustafsson, B.3
Brunk, U.T.4
-
12
-
-
0021856398
-
The role of iron in ferritin-and haemosiderin-mediated lipid peroxidation in liposomes
-
O'Connell MJ, Ward RJ, Baum H, Peters TJ. The role of iron in ferritin-and haemosiderin-mediated lipid peroxidation in liposomes. Biochem J. 1985;229:135-9.
-
(1985)
Biochem J.
, vol.229
, pp. 135-139
-
-
O'Connell, M.J.1
Ward, R.J.2
Baum, H.3
Peters, T.J.4
-
13
-
-
0017188972
-
Acid hydrolase activities and lysosomal integrity in liver biopsies from patients with iron overload
-
Peters TJ, Seymour CA. Acid hydrolase activities and lysosomal integrity in liver biopsies from patients with iron overload. Clin Sci Mol Med. 1976;50:75-8.
-
(1976)
Clin Sci Mol Med.
, vol.50
, pp. 75-78
-
-
Peters, T.J.1
Seymour, C.A.2
-
14
-
-
0018114375
-
Organelle pathology in primary and secondary haemochromatosis with special reference to lysosomal changes
-
Seymour CA, Peters TJ. Organelle pathology in primary and secondary haemochromatosis with special reference to lysosomal changes. Br J Haematol. 1978;40:239-53.
-
(1978)
Br J Haematol.
, vol.40
, pp. 239-253
-
-
Seymour, C.A.1
Peters, T.J.2
-
15
-
-
0021233287
-
Isolation of two lysosomal populations from iron-overloaded rat liver with different iron concentration and proteolytic activity
-
Hultcrantz R, Ahlberg J, Glaumann H. Isolation of two lysosomal populations from iron-overloaded rat liver with different iron concentration and proteolytic activity. Virchows Arch B Cell Pathol Incl Mol Pathol. 1984;47:55-65.
-
(1984)
Virchows Arch B Cell Pathol Incl Mol Pathol.
, vol.47
, pp. 55-65
-
-
Hultcrantz, R.1
Ahlberg, J.2
Glaumann, H.3
-
16
-
-
0022559519
-
Biliary excretion of iron from hepatocyte lysosomes in the rat. A major excretory pathway in experimental iron overload
-
LeSage GD, Kost LJ, Barham SS, LaRusso NF. Biliary excretion of iron from hepatocyte lysosomes in the rat. A major excretory pathway in experimental iron overload. J Clin Invest. 1986;77:90-7.
-
(1986)
J Clin Invest.
, vol.77
, pp. 90-97
-
-
LeSage, G.D.1
Kost, L.J.2
Barham, S.S.3
LaRusso, N.F.4
-
17
-
-
0027234615
-
Hepatic mitochondrial energy production in rats with chronic iron overload
-
Bacon BR, O'Neill R, Britton RS. Hepatic mitochondrial energy production in rats with chronic iron overload. Gastroenterology. 1993;105(4):1134-40.
-
(1993)
Gastroenterology.
, vol.105
, Issue.4
, pp. 1134-1140
-
-
Bacon, B.R.1
O'Neill, R.2
Britton, R.S.3
-
18
-
-
0022992599
-
Iron-induced peroxidative injury to isolated rat hepatic mitochondria
-
Bacon BR, O'Neill R, Park CH. Iron-induced peroxidative injury to isolated rat hepatic mitochondria. J Free Radic Biol Med. 1986;2:339-47.
-
(1986)
J Free Radic Biol Med.
, vol.2
, pp. 339-347
-
-
Bacon, B.R.1
O'Neill, R.2
Park, C.H.3
-
19
-
-
0141447370
-
Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis
-
Zhao M, Antunes F, Eaton JW, Brunk UT. Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis. Eur J Biochem. 2003;270:3778-86.
-
(2003)
Eur J Biochem.
, vol.270
, pp. 3778-3786
-
-
Zhao, M.1
Antunes, F.2
Eaton, J.W.3
Brunk, U.T.4
-
20
-
-
68949105901
-
Hydroxyl radical is produced via the Fenton reaction in submitochondrial particles under oxidative stress: implications for diseases associated with iron accumulation
-
Thomas C, Mackey MM, Diaz AA, Cox DP. Hydroxyl radical is produced via the Fenton reaction in submitochondrial particles under oxidative stress: implications for diseases associated with iron accumulation. Redox Rep. 2009;14:102-8.
-
(2009)
Redox Rep.
, vol.14
, pp. 102-108
-
-
Thomas, C.1
Mackey, M.M.2
Diaz, A.A.3
Cox, D.P.4
-
21
-
-
58149470840
-
Uncoupling and oxidative stress in liver mitochondria isolated from rats with acute iron overload
-
Pardo Andreu GL, Inada NM, Vercesi AE, Curti C. Uncoupling and oxidative stress in liver mitochondria isolated from rats with acute iron overload. Arch Toxicol. 2009;83:47-53.
-
(2009)
Arch Toxicol.
, vol.83
, pp. 47-53
-
-
Pardo Andreu, G.L.1
Inada, N.M.2
Vercesi, A.E.3
Curti, C.4
-
22
-
-
33645994183
-
Calcium, mitochondria and reperfusion injury: a pore way to die
-
Halestrap AP. Calcium, mitochondria and reperfusion injury: a pore way to die. Biochem Soc Trans. 2006;34:232-7.
-
(2006)
Biochem Soc Trans.
, vol.34
, pp. 232-237
-
-
Halestrap, A.P.1
-
23
-
-
1642347584
-
Iron-induced mitochondrial permeability transition in cultured hepatocytes
-
Rauen U, Petrat F, Sustmann R, de Groot H. Iron-induced mitochondrial permeability transition in cultured hepatocytes. J Hepatol. 2004;40:607-15.
-
(2004)
J Hepatol.
, vol.40
, pp. 607-615
-
-
Rauen, U.1
Petrat, F.2
Sustmann, R.3
de Groot, H.4
-
24
-
-
0025834853
-
Chronic dietary iron overload in rats results in impaired calcium sequestration by hepatic mitochondria and microsomes
-
Britton RS, O'Neill R, Bacon BR. Chronic dietary iron overload in rats results in impaired calcium sequestration by hepatic mitochondria and microsomes. Gastroenterology. 1991;101:806-11.
-
(1991)
Gastroenterology.
, vol.101
, pp. 806-811
-
-
Britton, R.S.1
O'Neill, R.2
Bacon, B.R.3
-
25
-
-
0024429957
-
Perturbation in liver mitochondrial Ca2+ homeostasis in experimental iron overload: a possible factor in cell injury
-
Masini A, Ceccarelli D, Trenti T, Corongiu FP, Muscatello U. Perturbation in liver mitochondrial Ca2+ homeostasis in experimental iron overload: a possible factor in cell injury. Biochim Biophys Acta. 1989;1014:133-40.
-
(1989)
Biochim Biophys Acta.
, vol.1014
, pp. 133-140
-
-
Masini, A.1
Ceccarelli, D.2
Trenti, T.3
Corongiu, F.P.4
Muscatello, U.5
-
26
-
-
16244379238
-
The permeability transition pore as a pathway for the release of mitochondrial DNA
-
Garcia N, Garcia JJ, Correa F, Chavez E. The permeability transition pore as a pathway for the release of mitochondrial DNA. Life Sci. 2005;76:2873-80.
-
(2005)
Life Sci.
, vol.76
, pp. 2873-2880
-
-
Garcia, N.1
Garcia, J.J.2
Correa, F.3
Chavez, E.4
-
27
-
-
0037133219
-
Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats
-
Walter PB, Knutson MD, Paler-Martinez A, et al. Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats. Proc Natl Acad Sci USA. 2002;99:2264-9.
-
(2002)
Proc Natl Acad Sci USA.
, vol.99
, pp. 2264-2269
-
-
Walter, P.B.1
Knutson, M.D.2
Paler-Martinez, A.3
-
28
-
-
14644393025
-
Mangifera indica L. Extract (vimang) inhibits Fe2+-citrate-induced lipoperoxidation in isolated rat liver mitochondria
-
Pardo Andreu G, Delgado R, Velho J, et al. Mangifera indica L. Extract (vimang) inhibits Fe2+-citrate-induced lipoperoxidation in isolated rat liver mitochondria. Pharmacol Res. 2005;51:427-35.
-
(2005)
Pharmacol Res.
, vol.51
, pp. 427-435
-
-
Pardo Andreu, G.1
Delgado, R.2
Velho, J.3
-
29
-
-
9644294192
-
Oxidative stress and lipid peroxidation-derived DNA-lesions in inflammation driven carcinogenesis
-
Bartsch H, Nair J. Oxidative stress and lipid peroxidation-derived DNA-lesions in inflammation driven carcinogenesis. Cancer Detect Prev. 2004;28:385-91.
-
(2004)
Cancer Detect Prev.
, vol.28
, pp. 385-391
-
-
Bartsch, H.1
Nair, J.2
-
30
-
-
0027326559
-
Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes
-
Uchida K, Szweda LI, Chae HZ, Stadtman ER. Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes. Proc Natl Acad Sci USA. 1993;90:8742-6.
-
(1993)
Proc Natl Acad Sci USA.
, vol.90
, pp. 8742-8746
-
-
Uchida, K.1
Szweda, L.I.2
Chae, H.Z.3
Stadtman, E.R.4
-
31
-
-
0037082350
-
Role of malondialdehyde-acetaldehyde adducts in liver injury
-
Tuma DJ. Role of malondialdehyde-acetaldehyde adducts in liver injury. Free Radic Biol Med. 2002;32:303-8.
-
(2002)
Free Radic Biol Med.
, vol.32
, pp. 303-308
-
-
Tuma, D.J.1
-
32
-
-
0034976152
-
The chemistry and biological effects of malondialdehyde-acetaldehyde adducts
-
doi: 218S
-
Thiele GM, Worrall S, Tuma DJ, et al. The chemistry and biological effects of malondialdehyde-acetaldehyde adducts. Alcohol Clin Exp Res. 2001;25(5 Suppl ISBRA):218S-24S. doi: 218S .
-
(2001)
Alcohol Clin Exp Res.
, vol.25
, Issue.5
, pp. 218S-224S
-
-
Thiele, G.M.1
Worrall, S.2
Tuma, D.J.3
-
33
-
-
0035672819
-
Malondialdehyde-acetaldehyde-protein adducts increase secretion of chemokines by rat hepatic stellate cells
-
Kharbanda KK, Todero SL, Shubert KA, Sorrell MF, Tuma DJ. Malondialdehyde-acetaldehyde-protein adducts increase secretion of chemokines by rat hepatic stellate cells. Alcohol. 2001;25:123-8.
-
(2001)
Alcohol.
, vol.25
, pp. 123-128
-
-
Kharbanda, K.K.1
Todero, S.L.2
Shubert, K.A.3
Sorrell, M.F.4
Tuma, D.J.5
-
34
-
-
0036471578
-
Effect of malondialdehyde-acetaldehyde-protein adducts on the protein kinase C-dependent secretion of urokinase-type plasminogen activator in hepatic stellate cells
-
Kharbanda KK, Shubert KA, Wyatt TA, Sorrell MF, Tuma DJ. Effect of malondialdehyde-acetaldehyde-protein adducts on the protein kinase C-dependent secretion of urokinase-type plasminogen activator in hepatic stellate cells. Biochem Pharmacol. 2002;63:553-62.
-
(2002)
Biochem Pharmacol.
, vol.63
, pp. 553-562
-
-
Kharbanda, K.K.1
Shubert, K.A.2
Wyatt, T.A.3
Sorrell, M.F.4
Tuma, D.J.5
-
35
-
-
0031948085
-
Lipid peroxidation-induced etheno-DNA adducts in the liver of patients with the genetic metal storage disorders Wilson's disease and primary hemochromatosis
-
Nair J, Carmichael PL, Fernando RC, et al. Lipid peroxidation-induced etheno-DNA adducts in the liver of patients with the genetic metal storage disorders Wilson's disease and primary hemochromatosis. Cancer Epidemiol Biomarkers Prev. 1998;7:435-40.
-
(1998)
Cancer Epidemiol Biomarkers Prev.
, vol.7
, pp. 435-440
-
-
Nair, J.1
Carmichael, P.L.2
Fernando, R.C.3
-
36
-
-
0000707647
-
Increased p53 mutation load in nontumorous human liver of Wilson disease and hemochromatosis: oxyradical overload diseases
-
Hussain SP, Raja K, Amstad PA, et al. Increased p53 mutation load in nontumorous human liver of Wilson disease and hemochromatosis: oxyradical overload diseases. Proc Natl Acad Sci USA. 2000;97:12770-5.
-
(2000)
Proc Natl Acad Sci USA.
, vol.97
, pp. 12770-12775
-
-
Hussain, S.P.1
Raja, K.2
Amstad, P.A.3
-
37
-
-
0030797051
-
Formation, prevention, and repair of DNA damage by iron/hydrogen peroxide
-
Henle ES, Linn S. Formation, prevention, and repair of DNA damage by iron/hydrogen peroxide. J Biol Chem. 1997;272:19095-8.
-
(1997)
J Biol Chem.
, vol.272
, pp. 19095-19098
-
-
Henle, E.S.1
Linn, S.2
-
38
-
-
75749131647
-
Narrative review: fibrotic diseases: cellular and molecular mechanisms and novel therapies
-
Rosenbloom J, Castro SV, Jimenez SA. Narrative review: fibrotic diseases: cellular and molecular mechanisms and novel therapies. Ann Intern Med. 2010;152:159-66.
-
(2010)
Ann Intern Med.
, vol.152
, pp. 159-166
-
-
Rosenbloom, J.1
Castro, S.V.2
Jimenez, S.A.3
-
40
-
-
70449086055
-
The natural history of drug-induced liver injury
-
Bjornsson E. The natural history of drug-induced liver injury. Semin Liver Dis. 2009;29:357-63.
-
(2009)
Semin Liver Dis.
, vol.29
, pp. 357-363
-
-
Bjornsson, E.1
-
41
-
-
77951622187
-
Viral hepatocarcinogenesis
-
Tsai WL, Chung RT. Viral hepatocarcinogenesis. Oncogene. 2010;29:2309-24.
-
(2010)
Oncogene.
, vol.29
, pp. 2309-2324
-
-
Tsai, W.L.1
Chung, R.T.2
-
43
-
-
0031054425
-
Hepatic stellate cell activation in genetic haemochromatosis. Lobular distribution, effect of increasing hepatic iron and response to phlebotomy
-
Ramm GA, Crawford DH, Powell LW, et al. Hepatic stellate cell activation in genetic haemochromatosis. Lobular distribution, effect of increasing hepatic iron and response to phlebotomy. J Hepatol. 1997;26:584-92.
-
(1997)
J Hepatol.
, vol.26
, pp. 584-592
-
-
Ramm, G.A.1
Crawford, D.H.2
Powell, L.W.3
-
45
-
-
0037460697
-
Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis
-
Bridle KR, Frazer DM, Wilkins SJ, et al. Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet. 2003;361:669-73.
-
(2003)
Lancet.
, vol.361
, pp. 669-673
-
-
Bridle, K.R.1
Frazer, D.M.2
Wilkins, S.J.3
-
47
-
-
0022656390
-
Value of hepatic iron measurements in early hemochromatosis and determination of the critical iron level associated with fibrosis
-
Bassett ML, Halliday JW, Powell LW. Value of hepatic iron measurements in early hemochromatosis and determination of the critical iron level associated with fibrosis. Hepatology. 1986;6:24-9.
-
(1986)
Hepatology.
, vol.6
, pp. 24-29
-
-
Bassett, M.L.1
Halliday, J.W.2
Powell, L.W.3
-
48
-
-
0035124088
-
Is there a threshold of hepatic iron concentration that leads to cirrhosis in C282Y hemochromatosis?
-
Adams PC. Is there a threshold of hepatic iron concentration that leads to cirrhosis in C282Y hemochromatosis? Am J Gastroenterol. 2001;96:567-9.
-
(2001)
Am J Gastroenterol.
, vol.96
, pp. 567-569
-
-
Adams, P.C.1
-
49
-
-
32644445055
-
Screening for hemochromatosis in asymptomatic subjects with or without a family history
-
Powell LW, Dixon JL, Ramm GA, et al. Screening for hemochromatosis in asymptomatic subjects with or without a family history. Arch Intern Med. 2006;166:294-301.
-
(2006)
Arch Intern Med.
, vol.166
, pp. 294-301
-
-
Powell, L.W.1
Dixon, J.L.2
Ramm, G.A.3
-
50
-
-
84991119207
-
Kupffer cell iron overload induces intercellular adhesion molecule-1 expression on hepatocytes in genetic hemochromatosis
-
Stal P, Broome U, Scheynius A, Befrits R, Hultcrantz R. Kupffer cell iron overload induces intercellular adhesion molecule-1 expression on hepatocytes in genetic hemochromatosis. Hepatology. 1995;21:1308-16.
-
(1995)
Hepatology.
, vol.21
, pp. 1308-1316
-
-
Stal, P.1
Broome, U.2
Scheynius, A.3
Befrits, R.4
Hultcrantz, R.5
-
51
-
-
47149091490
-
Environmental and genetic modifiers of the progression to fibrosis and cirrhosis in hemochromatosis
-
Wood MJ, Powell LW, Ramm GA. Environmental and genetic modifiers of the progression to fibrosis and cirrhosis in hemochromatosis. Blood. 2008;111:4456-62.
-
(2008)
Blood.
, vol.111
, pp. 4456-4462
-
-
Wood, M.J.1
Powell, L.W.2
Ramm, G.A.3
-
54
-
-
0025600464
-
Malondialdehyde and 4-hydroxynonenal protein adducts in plasma and liver of rats with iron overload
-
Houglum K, Filip M, Witztum JL, Chojkier M. Malondialdehyde and 4-hydroxynonenal protein adducts in plasma and liver of rats with iron overload. J Clin Invest. 1990;86:1991-8.
-
(1990)
J Clin Invest.
, vol.86
, pp. 1991-1998
-
-
Houglum, K.1
Filip, M.2
Witztum, J.L.3
Chojkier, M.4
-
55
-
-
0030866199
-
Excess iron induces hepatic oxidative stress and transforming growth factor beta1 in genetic hemochromatosis
-
Houglum K, Ramm GA, Crawford DH, et al. Excess iron induces hepatic oxidative stress and transforming growth factor beta1 in genetic hemochromatosis. Hepatology. 1997;26:605-10.
-
(1997)
Hepatology.
, vol.26
, pp. 605-610
-
-
Houglum, K.1
Ramm, G.A.2
Crawford, D.H.3
-
56
-
-
0028956616
-
Molecular and cellular aspects of iron-induced hepatic cirrhosis in rodents
-
Pietrangelo A, Gualdi R, Casalgrandi G, Montosi G, Ventura E. Molecular and cellular aspects of iron-induced hepatic cirrhosis in rodents. J Clin Invest. 1995;95:1824-31.
-
(1995)
J Clin Invest.
, vol.95
, pp. 1824-1831
-
-
Pietrangelo, A.1
Gualdi, R.2
Casalgrandi, G.3
Montosi, G.4
Ventura, E.5
-
57
-
-
4444283611
-
Iron-induced interleukin-6 gene expression: possible mediation through the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways
-
Dai J, Huang C, Wu J, et al. Iron-induced interleukin-6 gene expression: possible mediation through the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways. Toxicology. 2004;203:199-209.
-
(2004)
Toxicology.
, vol.203
, pp. 199-209
-
-
Dai, J.1
Huang, C.2
Wu, J.3
-
58
-
-
0035990192
-
Iron overload decreases the protective effect of tumour necrosis factor-alpha on rat hepatocytes exposed to oxidative stress
-
Hagen K, Eckes K, Melefors O, Hultcrantz R. Iron overload decreases the protective effect of tumour necrosis factor-alpha on rat hepatocytes exposed to oxidative stress. Scand J Gastroenterol. 2002;37:725-31.
-
(2002)
Scand J Gastroenterol.
, vol.37
, pp. 725-731
-
-
Hagen, K.1
Eckes, K.2
Melefors, O.3
Hultcrantz, R.4
-
59
-
-
0032990360
-
Susceptibility of cultured rat hepatocytes to oxidative stress by peroxides and iron. The extracellular matrix affects the toxicity of tert-butyl hydroperoxide
-
Hagen K, Zhu C, Melefors O, Hultcrantz R. Susceptibility of cultured rat hepatocytes to oxidative stress by peroxides and iron. The extracellular matrix affects the toxicity of tert-butyl hydroperoxide. Int J Biochem Cell Biol. 1999;31:499-508.
-
(1999)
Int J Biochem Cell Biol.
, vol.31
, pp. 499-508
-
-
Hagen, K.1
Zhu, C.2
Melefors, O.3
Hultcrantz, R.4
-
60
-
-
33747605553
-
Cytochrome P450 2E1-dependent oxidant stress and upregulation of anti-oxidant defense in liver cells
-
Cederbaum AI. Cytochrome P450 2E1-dependent oxidant stress and upregulation of anti-oxidant defense in liver cells. J Gastroenterol Hepatol. 2006;21 Suppl 3:S22-5.
-
(2006)
J Gastroenterol Hepatol.
, vol.21
, pp. S22-S25
-
-
Cederbaum, A.I.1
-
61
-
-
21144435281
-
The molecular basis of ferroportin-linked hemochromatosis
-
De Domenico I, Ward DM, Nemeth E, et al. The molecular basis of ferroportin-linked hemochromatosis. Proc Natl Acad Sci USA. 2005;102:8955-60.
-
(2005)
Proc Natl Acad Sci USA.
, vol.102
, pp. 8955-8960
-
-
De Domenico, I.1
Ward, D.M.2
Nemeth, E.3
-
63
-
-
0042384695
-
Iron-dependent activation of NF-kappaB in kupffer cells: a priming mechanism for alcoholic liver disease
-
Xiong S, She H, Sung CK, Tsukamoto H. Iron-dependent activation of NF-kappaB in kupffer cells: a priming mechanism for alcoholic liver disease. Alcohol. 2003;30:107-13.
-
(2003)
Alcohol.
, vol.30
, pp. 107-113
-
-
Xiong, S.1
She, H.2
Sung, C.K.3
Tsukamoto, H.4
-
64
-
-
0030858597
-
Role of iron in NF-kappa B activation and cytokine gene expression by rat hepatic macrophages
-
Lin M, Rippe RA, Niemela O, Brittenham G, Tsukamoto H. Role of iron in NF-kappa B activation and cytokine gene expression by rat hepatic macrophages. Am J Physiol. 1997;272:G1355-1364.
-
(1997)
Am J Physiol.
, vol.272
, pp. G1355-G1364
-
-
Lin, M.1
Rippe, R.A.2
Niemela, O.3
Brittenham, G.4
Tsukamoto, H.5
-
65
-
-
0029144666
-
Roles of oxidative stress in activation of kupffer and Ito cells in liver fibrogenesis
-
Tsukamoto H, Rippe R, Niemela O, Lin M. Roles of oxidative stress in activation of kupffer and Ito cells in liver fibrogenesis. J Gastroenterol Hepatol. 1995;10 Suppl 1:S50-3.
-
(1995)
J Gastroenterol Hepatol.
, vol.10
, pp. S50-S53
-
-
Tsukamoto, H.1
Rippe, R.2
Niemela, O.3
Lin, M.4
-
66
-
-
0028235640
-
Interleukin-6 enhances hepatic transferrin uptake and ferritin expression in rats
-
Kobune M, Kohgo Y, Kato J, Miyazaki E, Niitsu Y. Interleukin-6 enhances hepatic transferrin uptake and ferritin expression in rats. Hepatology. 1994;19(6):1468-75.
-
(1994)
Hepatology.
, vol.19
, Issue.6
, pp. 1468-1475
-
-
Kobune, M.1
Kohgo, Y.2
Kato, J.3
Miyazaki, E.4
Niitsu, Y.5
-
67
-
-
0032401893
-
Expression and regulation of intercellular adhesion molecule-1 (ICAM-1) in organotypic cultures of rat liver tissue
-
Oudar O, Moreau A, Feldmann G, Scoazec JY. Expression and regulation of intercellular adhesion molecule-1 (ICAM-1) in organotypic cultures of rat liver tissue. J Hepatol. 1998;29:901-9.
-
(1998)
J Hepatol.
, vol.29
, pp. 901-909
-
-
Oudar, O.1
Moreau, A.2
Feldmann, G.3
Scoazec, J.Y.4
-
68
-
-
0037371516
-
ICAM-1 triggers liver regeneration through leukocyte recruitment and kupffer cell-dependent release of TNF-alpha/IL-6 in mice
-
Selzner N, Selzner M, Odermatt B, et al. ICAM-1 triggers liver regeneration through leukocyte recruitment and kupffer cell-dependent release of TNF-alpha/IL-6 in mice. Gastroenterology. 2003;124:692-700.
-
(2003)
Gastroenterology.
, vol.124
, pp. 692-700
-
-
Selzner, N.1
Selzner, M.2
Odermatt, B.3
-
69
-
-
0142151769
-
Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression
-
Canbay A, Feldstein AE, Higuchi H, et al. Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression. Hepatology. 2003;38:1188-98.
-
(2003)
Hepatology.
, vol.38
, pp. 1188-1198
-
-
Canbay, A.1
Feldstein, A.E.2
Higuchi, H.3
-
70
-
-
0029160569
-
Experimental liver cirrhosis induced by alcohol and iron
-
Tsukamoto H, Horne W, Kamimura S, et al. Experimental liver cirrhosis induced by alcohol and iron. J Clin Invest. 1995;96:620-30.
-
(1995)
J Clin Invest.
, vol.96
, pp. 620-630
-
-
Tsukamoto, H.1
Horne, W.2
Kamimura, S.3
-
71
-
-
0030465440
-
Role of kupffer cell-derived reactive oxygen intermediates in alcoholic liver disease in rats in vivo
-
Takeyama Y, Kamimura S, Kuroiwa A, et al. Role of kupffer cell-derived reactive oxygen intermediates in alcoholic liver disease in rats in vivo. Alcohol Clin Exp Res. 1996;20(9 Suppl):335A-9A.
-
(1996)
Alcohol Clin Exp Res.
, vol.20
, Issue.9
, pp. 335A-339A
-
-
Takeyama, Y.1
Kamimura, S.2
Kuroiwa, A.3
-
72
-
-
0842263988
-
Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes
-
Zhang AS, Xiong S, Tsukamoto H, Enns CA. Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes. Blood. 2004;103:1509-14.
-
(2004)
Blood.
, vol.103
, pp. 1509-1514
-
-
Zhang, A.S.1
Xiong, S.2
Tsukamoto, H.3
Enns, C.A.4
-
73
-
-
0027974170
-
TGF-beta and collagen-alpha 1 (I) gene expression are increased in hepatic acinar zone 1 of rats with iron overload
-
Houglum K, Bedossa P, Chojkier M. TGF-beta and collagen-alpha 1 (I) gene expression are increased in hepatic acinar zone 1 of rats with iron overload. Am J Physiol. 1994;267:G908-13.
-
(1994)
Am J Physiol.
, vol.267
, pp. G908-G913
-
-
Houglum, K.1
Bedossa, P.2
Chojkier, M.3
-
74
-
-
0020510215
-
Iron overload of spleen, liver and kidney as a consequence of hemolytic anaemia
-
Solecki R, von Zglinicki T, Muller HM, Clausing P. Iron overload of spleen, liver and kidney as a consequence of hemolytic anaemia. Exp Pathol. 1983;23:227-35.
-
(1983)
Exp Pathol.
, vol.23
, pp. 227-235
-
-
Solecki, R.1
von Zglinicki, T.2
Muller, H.M.3
Clausing, P.4
-
75
-
-
0037384989
-
Evidence for a sub-morphological inflammatory process in the liver in haemochromatosis
-
Bridle KR, Crawford DH, Fletcher LM, Smith JL, Powell LW, Ramm GA. Evidence for a sub-morphological inflammatory process in the liver in haemochromatosis. J Hepatol. 2003;38:426-33.
-
(2003)
J Hepatol.
, vol.38
, pp. 426-433
-
-
Bridle, K.R.1
Crawford, D.H.2
Fletcher, L.M.3
Smith, J.L.4
Powell, L.W.5
Ramm, G.A.6
-
76
-
-
0026601599
-
Liver pathology in genetic hemochromatosis: a review of 135 homozygous cases and their bioclinical correlations
-
Deugnier YM, Loreal O, Turlin B, et al. Liver pathology in genetic hemochromatosis: a review of 135 homozygous cases and their bioclinical correlations. Gastroenterology. 1992;102:2050-9.
-
(1992)
Gastroenterology.
, vol.102
, pp. 2050-2059
-
-
Deugnier, Y.M.1
Loreal, O.2
Turlin, B.3
-
77
-
-
0035130677
-
Hepatic damage in C282Y homozygotes relates to low numbers of CD8+ cells in the liver lobuli
-
Cardoso EM, Hagen K, de Sousa M, Hultcrantz R. Hepatic damage in C282Y homozygotes relates to low numbers of CD8+ cells in the liver lobuli. Eur J Clin Invest. 2001;31:45-53.
-
(2001)
Eur J Clin Invest.
, vol.31
, pp. 45-53
-
-
Cardoso, E.M.1
Hagen, K.2
de Sousa, M.3
Hultcrantz, R.4
-
78
-
-
12644281617
-
Relative impact of HLA phenotype and CD4-CD8 ratios on the clinical expression of hemochromatosis
-
Porto G, Vicente C, Teixeira MA, et al. Relative impact of HLA phenotype and CD4-CD8 ratios on the clinical expression of hemochromatosis. Hepatology. 1997;25:397-402.
-
(1997)
Hepatology.
, vol.25
, pp. 397-402
-
-
Porto, G.1
Vicente, C.2
Teixeira, M.A.3
-
79
-
-
58949096547
-
Lymphotoxin-beta receptor signaling regulates hepatic stellate cell function and wound healing in a murine model of chronic liver injury
-
Ruddell RG, Knight B, Tirnitz-Parker JE, et al. Lymphotoxin-beta receptor signaling regulates hepatic stellate cell function and wound healing in a murine model of chronic liver injury. Hepatology. 2009;49:227-39.
-
(2009)
Hepatology.
, vol.49
, pp. 227-239
-
-
Ruddell, R.G.1
Knight, B.2
Tirnitz-Parker, J.E.3
-
80
-
-
0030017390
-
Chronic iron overload in rats induces oval cells in the liver
-
Smith PG, Yeoh GC. Chronic iron overload in rats induces oval cells in the liver. Am J Pathol. 1996;149:389-98.
-
(1996)
Am J Pathol.
, vol.149
, pp. 389-398
-
-
Smith, P.G.1
Yeoh, G.C.2
-
81
-
-
0027165898
-
Intralobular heterogeneity of perisinusoidal stellate cells in porcine liver
-
Wake K, Sato T. Intralobular heterogeneity of perisinusoidal stellate cells in porcine liver. Cell Tissue Res. 1993;273:227-37.
-
(1993)
Cell Tissue Res.
, vol.273
, pp. 227-237
-
-
Wake, K.1
Sato, T.2
-
82
-
-
0031594818
-
Zonal and regional differences identified from precision mapping of vitamin a-storing lipid droplets of the hepatic stellate cells in pig liver: a novel concept of addressing the intralobular area of heterogeneity
-
Zou Z, Ekataksin W, Wake K. Zonal and regional differences identified from precision mapping of vitamin a-storing lipid droplets of the hepatic stellate cells in pig liver: a novel concept of addressing the intralobular area of heterogeneity. Hepatology. 1998;27:1098-108.
-
(1998)
Hepatology.
, vol.27
, pp. 1098-1108
-
-
Zou, Z.1
Ekataksin, W.2
Wake, K.3
-
83
-
-
35948954244
-
Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver
-
Friedman SL. Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev. 2008;88:125-72.
-
(2008)
Physiol Rev.
, vol.88
, pp. 125-172
-
-
Friedman, S.L.1
-
84
-
-
33748798900
-
A role for serotonin (5-HT) in hepatic stellate cell function and liver fibrosis
-
Ruddell RG, Oakley F, Hussain Z, et al. A role for serotonin (5-HT) in hepatic stellate cell function and liver fibrosis. Am J Pathol. 2006;169:861-76.
-
(2006)
Am J Pathol.
, vol.169
, pp. 861-876
-
-
Ruddell, R.G.1
Oakley, F.2
Hussain, Z.3
-
85
-
-
0031149802
-
Bone morphogenetic protein-6 is expressed in nonparenchymal liver cells and upregulated by transforming growth factor-beta 1
-
Knittel T, Fellmer P, Muller L, Ramadori G. Bone morphogenetic protein-6 is expressed in nonparenchymal liver cells and upregulated by transforming growth factor-beta 1. Exp Cell Res. 1997;232:263-9.
-
(1997)
Exp Cell Res.
, vol.232
, pp. 263-269
-
-
Knittel, T.1
Fellmer, P.2
Muller, L.3
Ramadori, G.4
-
86
-
-
63449103712
-
BMP6 Is a key endogenous regulator of hepcidin expression and iron metabolism
-
Andriopoulos Jr B, Corradini E, Xia Y, et al. BMP6 Is a key endogenous regulator of hepcidin expression and iron metabolism. Nat Genet. 2009;41:482-7.
-
(2009)
Nat Genet.
, vol.41
, pp. 482-487
-
-
Andriopoulos, B.1
Corradini, E.2
Xia, Y.3
-
87
-
-
63449122819
-
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
-
Meynard D, Kautz L, Darnaud V, et al. Lack of the bone morphogenetic protein BMP6 induces massive iron overload. Nat Genet. 2009;41:478-81.
-
(2009)
Nat Genet.
, vol.41
, pp. 478-481
-
-
Meynard, D.1
Kautz, L.2
Darnaud, V.3
-
88
-
-
0028953697
-
Chronic iron overload causes activation of rat lipocytes in vivo
-
Ramm GA, Li SC, Li L, et al. Chronic iron overload causes activation of rat lipocytes in vivo. Am J Physiol. 1995;268:G451-458.
-
(1995)
Am J Physiol.
, vol.268
, pp. G451-G458
-
-
Ramm, G.A.1
Li, S.C.2
Li, L.3
-
89
-
-
0030854654
-
Hepatic stellate cell immunodetection and cirrhotic evolution of viral hepatitis in liver allografts
-
Guido M, Rugge M, Leandro G, Fiel IM, Thung SN. Hepatic stellate cell immunodetection and cirrhotic evolution of viral hepatitis in liver allografts. Hepatology. 1997;26:310-4.
-
(1997)
Hepatology.
, vol.26
, pp. 310-314
-
-
Guido, M.1
Rugge, M.2
Leandro, G.3
Fiel, I.M.4
Thung, S.N.5
-
90
-
-
0031837715
-
Evidence for altered hepatic matrix degradation in genetic haemochromatosis
-
George DK, Ramm GA, Powell LW, et al. Evidence for altered hepatic matrix degradation in genetic haemochromatosis. Gut. 1998;42:715-20.
-
(1998)
Gut.
, vol.42
, pp. 715-720
-
-
George, D.K.1
Ramm, G.A.2
Powell, L.W.3
-
91
-
-
0026720588
-
Human hepatic lipocytes synthesize tissue inhibitor of metalloproteinases-1. Implications for regulation of matrix degradation in liver
-
Iredale JP, Murphy G, Hembry RM, Friedman SL, Arthur MJ. Human hepatic lipocytes synthesize tissue inhibitor of metalloproteinases-1. Implications for regulation of matrix degradation in liver. J Clin Invest. 1992;90:282-7.
-
(1992)
J Clin Invest.
, vol.90
, pp. 282-287
-
-
Iredale, J.P.1
Murphy, G.2
Hembry, R.M.3
Friedman, S.L.4
Arthur, M.J.5
-
92
-
-
0037406902
-
Identification and characterization of the hepatic stellate cell transferrin receptor
-
Bridle KR, Crawford DH, Ramm GA. Identification and characterization of the hepatic stellate cell transferrin receptor. Am J Pathol. 2003;162:1661-7.
-
(2003)
Am J Pathol.
, vol.162
, pp. 1661-1667
-
-
Bridle, K.R.1
Crawford, D.H.2
Ramm, G.A.3
-
93
-
-
0028338934
-
Identification and characterization of a receptor for tissue ferritin on activated rat lipocytes
-
Ramm GA, Britton RS, O'Neill R, Bacon BR. Identification and characterization of a receptor for tissue ferritin on activated rat lipocytes. J Clin Invest. 1994;94:9-15.
-
(1994)
J Clin Invest.
, vol.94
, pp. 9-15
-
-
Ramm, G.A.1
Britton, R.S.2
O'Neill, R.3
Bacon, B.R.4
-
94
-
-
0035128122
-
Inhibition of the NA(+)/H(+) exchanger reduces rat hepatic stellate cell activity and liver fibrosis: an in vitro and in vivo study
-
Benedetti A, Di Sario A, Casini A, et al. Inhibition of the NA(+)/H(+) exchanger reduces rat hepatic stellate cell activity and liver fibrosis: an in vitro and in vivo study. Gastroenterology. 2001;120:545-56.
-
(2001)
Gastroenterology.
, vol.120
, pp. 545-556
-
-
Benedetti, A.1
Di Sario, A.2
Casini, A.3
-
95
-
-
0036775797
-
Effect of free iron on collagen synthesis, cell proliferation and MMP-2 expression in rat hepatic stellate cells
-
Gardi C, Arezzini B, Fortino V, Comporti M. Effect of free iron on collagen synthesis, cell proliferation and MMP-2 expression in rat hepatic stellate cells. Biochem Pharmacol. 2002;64:1139-45.
-
(2002)
Biochem Pharmacol.
, vol.64
, pp. 1139-1145
-
-
Gardi, C.1
Arezzini, B.2
Fortino, V.3
Comporti, M.4
-
96
-
-
0031800450
-
Hepatic stellate cells are not subjected to oxidant stress during iron-induced fibrogenesis in rodents
-
Montosi G, Garuti C, Martinelli S, Pietrangelo A. Hepatic stellate cells are not subjected to oxidant stress during iron-induced fibrogenesis in rodents. Hepatology. 1998;27:1611-22.
-
(1998)
Hepatology.
, vol.27
, pp. 1611-1622
-
-
Montosi, G.1
Garuti, C.2
Martinelli, S.3
Pietrangelo, A.4
-
97
-
-
0033839672
-
Changes in gene expression with iron loading and chelation in cardiac myocytes and non-myocytic fibroblasts
-
Parkes JG, Liu Y, Sirna JB, Templeton DM. Changes in gene expression with iron loading and chelation in cardiac myocytes and non-myocytic fibroblasts. J Mol Cell Cardiol. 2000;32:233-46.
-
(2000)
J Mol Cell Cardiol.
, vol.32
, pp. 233-246
-
-
Parkes, J.G.1
Liu, Y.2
Sirna, J.B.3
Templeton, D.M.4
-
98
-
-
25844475970
-
TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis
-
Chen TT, Li L, Chung DH, et al. TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis. J Exp Med. 2005;202(7):955-65.
-
(2005)
J Exp Med.
, vol.202
, Issue.7
, pp. 955-965
-
-
Chen, T.T.1
Li, L.2
Chung, D.H.3
-
99
-
-
58149477863
-
Scara5 is a ferritin receptor mediating non-transferrin iron delivery
-
Li JY, Paragas N, Ned RM, et al. Scara5 is a ferritin receptor mediating non-transferrin iron delivery. Dev Cell. 2009;16:35-46.
-
(2009)
Dev Cell.
, vol.16
, pp. 35-46
-
-
Li, J.Y.1
Paragas, N.2
Ned, R.M.3
-
100
-
-
56749156761
-
Tim-2 is the receptor for H-ferritin on oligodendrocytes
-
Todorich B, Zhang X, Slagle-Webb B, Seaman WE, Connor JR. Tim-2 is the receptor for H-ferritin on oligodendrocytes. J Neurochem. 2008;107:1495-505.
-
(2008)
J Neurochem.
, vol.107
, pp. 1495-1505
-
-
Todorich, B.1
Zhang, X.2
Slagle-Webb, B.3
Seaman, W.E.4
Connor, J.R.5
-
101
-
-
77649268711
-
Binding and uptake of H-ferritin are mediated by human transferrin receptor-1
-
Li L, Fang CJ, Ryan JC, et al. Binding and uptake of H-ferritin are mediated by human transferrin receptor-1. Proc Natl Acad Sci USA. 2010;107:3505-10.
-
(2010)
Proc Natl Acad Sci USA.
, vol.107
, pp. 3505-3510
-
-
Li, L.1
Fang, C.J.2
Ryan, J.C.3
-
102
-
-
63349103637
-
Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells
-
Ruddell RG, Hoang-Le D, Barwood JM, et al. Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells. Hepatology. 2009;49:887-900.
-
(2009)
Hepatology.
, vol.49
, pp. 887-900
-
-
Ruddell, R.G.1
Hoang-Le, D.2
Barwood, J.M.3
-
103
-
-
0035816696
-
Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells
-
Kawada N, Kristensen DB, Asahina K, et al. Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells. J Biol Chem. 2001;276:25318-23.
-
(2001)
J Biol Chem.
, vol.276
, pp. 25318-25323
-
-
Kawada, N.1
Kristensen, D.B.2
Asahina, K.3
-
104
-
-
85047691361
-
Cytoglobin/STAP, its unique localization in splanchnic fibroblastlike cells and function in organ fibrogenesis
-
Nakatani K, Okuyama H, Shimahara Y, et al. Cytoglobin/STAP, its unique localization in splanchnic fibroblastlike cells and function in organ fibrogenesis. Lab Invest. 2004;84:91-101.
-
(2004)
Lab Invest.
, vol.84
, pp. 91-101
-
-
Nakatani, K.1
Okuyama, H.2
Shimahara, Y.3
-
105
-
-
33646888232
-
Cytoglobin overexpression protects against damage-induced fibrosis
-
Xu R, Harrison PM, Chen M, et al. Cytoglobin overexpression protects against damage-induced fibrosis. Mol Ther. 2006;13:1093-100.
-
(2006)
Mol Ther.
, vol.13
, pp. 1093-1100
-
-
Xu, R.1
Harrison, P.M.2
Chen, M.3
-
106
-
-
0027226140
-
Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen alpha 1 (I) gene expression in human liver fat-storing cells
-
Parola M, Pinzani M, Casini A, et al. Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen alpha 1 (I) gene expression in human liver fat-storing cells. Biochem Biophys Res Commun. 1993;194:1044-50.
-
(1993)
Biochem Biophys Res Commun.
, vol.194
, pp. 1044-1050
-
-
Parola, M.1
Pinzani, M.2
Casini, A.3
-
107
-
-
0031915552
-
Fibrogenic effect of oxidative stress on rat hepatic stellate cells
-
Svegliati Baroni G, D'Ambrosio L, Ferretti G, et al. Fibrogenic effect of oxidative stress on rat hepatic stellate cells. Hepatology. 1998;27:720-6.
-
(1998)
Hepatology.
, vol.27
, pp. 720-726
-
-
Svegliati Baroni, G.1
D'Ambrosio, L.2
Ferretti, G.3
-
108
-
-
0027753777
-
Oxidative stress, antioxidants, and alcoholic liver fibrogenesis
-
Tsukamoto H. Oxidative stress, antioxidants, and alcoholic liver fibrogenesis. Alcohol. 1993;10:465-7.
-
(1993)
Alcohol.
, vol.10
, pp. 465-467
-
-
Tsukamoto, H.1
-
109
-
-
0036139102
-
Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species
-
Nieto N, Friedman SL, Cederbaum AI. Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species. Hepatology. 2002;35:62-73.
-
(2002)
Hepatology.
, vol.35
, pp. 62-73
-
-
Nieto, N.1
Friedman, S.L.2
Cederbaum, A.I.3
-
110
-
-
0041488842
-
Modulation of stellate cell proliferation and gene expression by rat hepatocytes: effect of toxic iron overload
-
Parkes JG, Templeton DM. Modulation of stellate cell proliferation and gene expression by rat hepatocytes: effect of toxic iron overload. Toxicol Lett. 2003;144:225-33.
-
(2003)
Toxicol Lett.
, vol.144
, pp. 225-233
-
-
Parkes, J.G.1
Templeton, D.M.2
-
111
-
-
0036062649
-
Aldehydic products of lipid peroxidation do not directly activate rat hepatic stellate cells
-
Olynyk JK, Khan NA, Ramm GA, et al. Aldehydic products of lipid peroxidation do not directly activate rat hepatic stellate cells. J Gastroenterol Hepatol. 2002;17:785-90.
-
(2002)
J Gastroenterol Hepatol.
, vol.17
, pp. 785-790
-
-
Olynyk, J.K.1
Khan, N.A.2
Ramm, G.A.3
-
113
-
-
0036185832
-
Risk factors of fibrosis in alcohol-induced liver disease
-
Raynard B, Balian A, Fallik D, et al. Risk factors of fibrosis in alcohol-induced liver disease. Hepatology. 2002;35:635-8.
-
(2002)
Hepatology.
, vol.35
, pp. 635-638
-
-
Raynard, B.1
Balian, A.2
Fallik, D.3
-
114
-
-
28844482171
-
Steatosis is a cofactor in liver injury in hemochromatosis
-
Powell EE, Ali A, Clouston AD, et al. Steatosis is a cofactor in liver injury in hemochromatosis. Gastroenterology. 2005;129:1937-43.
-
(2005)
Gastroenterology.
, vol.129
, pp. 1937-1943
-
-
Powell, E.E.1
Ali, A.2
Clouston, A.D.3
-
115
-
-
0029876789
-
Vitamin E decreases hepatic levels of aldehyde-derived peroxidation products in rats with iron overload
-
Parkkila S, Niemela O, Britton RS, et al. Vitamin E decreases hepatic levels of aldehyde-derived peroxidation products in rats with iron overload. Am J Physiol. 1996;270:G376-84.
-
(1996)
Am J Physiol.
, vol.270
, pp. G376-G384
-
-
Parkkila, S.1
Niemela, O.2
Britton, R.S.3
-
116
-
-
33847149630
-
Iron overload in Hepc1(-/-) mice is not impairing glucose homeostasis
-
Ramey G, Faye A, Durel B, Viollet B, Vaulont S. Iron overload in Hepc1(-/-) mice is not impairing glucose homeostasis. FEBS Lett. 2007;581:1053-7.
-
(2007)
FEBS Lett.
, vol.581
, pp. 1053-1057
-
-
Ramey, G.1
Faye, A.2
Durel, B.3
Viollet, B.4
Vaulont, S.5
-
117
-
-
0027512675
-
Morphologic and functional evaluation of the exocrine pancreas in betathalassemia major
-
Gullo L, Corcioni E, Brancati C, et al. Morphologic and functional evaluation of the exocrine pancreas in betathalassemia major. Pancreas. 1993;8:176-80.
-
(1993)
Pancreas.
, vol.8
, pp. 176-180
-
-
Gullo, L.1
Corcioni, E.2
Brancati, C.3
-
118
-
-
0025933977
-
Transferrin receptors and selective iron deposition in pancreatic B cells of iron-overloaded rats
-
Lu JP, Hayashi K, Okada S, Awai M. Transferrin receptors and selective iron deposition in pancreatic B cells of iron-overloaded rats. Acta Pathol Jpn. 1991;41:647-52.
-
(1991)
Acta Pathol Jpn.
, vol.41
, pp. 647-652
-
-
Lu, J.P.1
Hayashi, K.2
Okada, S.3
Awai, M.4
-
119
-
-
43849091250
-
Pancreatic beta-cells express hepcidin, an iron-uptake regulatory peptide
-
Kulaksiz H, Fein E, Redecker P, et al. Pancreatic beta-cells express hepcidin, an iron-uptake regulatory peptide. J Endocrinol. 2008;197:241-9.
-
(2008)
J Endocrinol.
, vol.197
, pp. 241-249
-
-
Kulaksiz, H.1
Fein, E.2
Redecker, P.3
-
120
-
-
77952628680
-
Iron restriction improves type 2 diabetes mellitus in otsuka long-Evans Tokushima fatty rats
-
Minamiyama Y, Takemura S, Kodai S, et al. Iron restriction improves type 2 diabetes mellitus in otsuka long-Evans Tokushima fatty rats. Am J Physiol Endocrinol Metab. 2010;298:E1140-9.
-
(2010)
Am J Physiol Endocrinol Metab.
, vol.298
, pp. E1140-E1149
-
-
Minamiyama, Y.1
Takemura, S.2
Kodai, S.3
-
121
-
-
39649101196
-
Activation of peroxisome proliferator-activated receptor (PPAR)delta promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men
-
Riserus U, Sprecher D, Johnson T, et al. Activation of peroxisome proliferator-activated receptor (PPAR)delta promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men. Diabetes. 2008;57:332-9.
-
(2008)
Diabetes.
, vol.57
, pp. 332-339
-
-
Riserus, U.1
Sprecher, D.2
Johnson, T.3
-
122
-
-
45249089262
-
Oxidative stress: the vulnerable beta-cell
-
Lenzen S. Oxidative stress: the vulnerable beta-cell. Biochem Soc Trans. 2008;36:343-7.
-
(2008)
Biochem Soc Trans.
, vol.36
, pp. 343-347
-
-
Lenzen, S.1
-
123
-
-
34547702300
-
HFE genotypes in patients with chronic pancreatitis and pancreatic adenocarcinoma
-
Hucl T, Kylanpaa-Back ML, Witt H, et al. HFE genotypes in patients with chronic pancreatitis and pancreatic adenocarcinoma. Genet Med. 2007;9:479-83.
-
(2007)
Genet Med.
, vol.9
, pp. 479-483
-
-
Hucl, T.1
Kylanpaa-Back, M.L.2
Witt, H.3
-
124
-
-
0027957740
-
In vitro inhibition of insulin release by blood mononuclear cells from insulin-dependent diabetic and healthy subjects: synergistic action of IL-1 and TNF
-
Ablamunits V, Baranova F, Mandrup-Poulsen T, Nerup J. In vitro inhibition of insulin release by blood mononuclear cells from insulin-dependent diabetic and healthy subjects: synergistic action of IL-1 and TNF. Cell Transplant. 1994;3:55-60.
-
(1994)
Cell Transplant.
, vol.3
, pp. 55-60
-
-
Ablamunits, V.1
Baranova, F.2
Mandrup-Poulsen, T.3
Nerup, J.4
-
125
-
-
0030481409
-
Interleukin-1-beta, tumour necrosis factor-alpha, islet-cell antibody, and insulin secretion in children with thalassemia major on long-term blood transfusion
-
el Nawawy A, Soliman AT, el Azzouni O, et al. Interleukin-1-beta, tumour necrosis factor-alpha, islet-cell antibody, and insulin secretion in children with thalassemia major on long-term blood transfusion. J Trop Pediatr. 1996;42:362-4.
-
(1996)
J Trop Pediatr.
, vol.42
, pp. 362-364
-
-
el Nawawy, A.1
Soliman, A.T.2
el Azzouni, O.3
-
126
-
-
33744468286
-
Insulin resistance and beta cell function in chronically transfused patients of thalassemia major
-
Suvarna J, Ingle H, Deshmukh CT. Insulin resistance and beta cell function in chronically transfused patients of thalassemia major. Indian Pediatr. 2006;43:393-400.
-
(2006)
Indian Pediatr.
, vol.43
, pp. 393-400
-
-
Suvarna, J.1
Ingle, H.2
Deshmukh, C.T.3
-
127
-
-
0346665875
-
Insulin sensitivity and beta-cell secretion in thalassaemia major with secondary haemochromatosis: assessment by oral glucose tolerance test
-
Cario H, Holl RW, Debatin KM, Kohne E. Insulin sensitivity and beta-cell secretion in thalassaemia major with secondary haemochromatosis: assessment by oral glucose tolerance test. Eur J Pediatr. 2003;162:139-46.
-
(2003)
Eur J Pediatr.
, vol.162
, pp. 139-146
-
-
Cario, H.1
Holl, R.W.2
Debatin, K.M.3
Kohne, E.4
-
128
-
-
0033545541
-
Rising incidence of hepatocellular carcinoma in the United States
-
El-Serag HB, Mason AC. Rising incidence of hepatocellular carcinoma in the United States. N Engl J Med. 1999;340:745-50.
-
(1999)
N Engl J Med.
, vol.340
, pp. 745-750
-
-
El-Serag, H.B.1
Mason, A.C.2
-
129
-
-
1842426695
-
Increased survival of cirrhotic patients with a hepatocellular carcinoma detected during surveillance
-
Sangiovanni A, Del Ninno E, Fasani P, et al. Increased survival of cirrhotic patients with a hepatocellular carcinoma detected during surveillance. Gastroenterology. 2004;126:1005-14.
-
(2004)
Gastroenterology.
, vol.126
, pp. 1005-1014
-
-
Sangiovanni, A.1
Del Ninno, E.2
Fasani, P.3
-
130
-
-
10744232491
-
Cancer risk in patients with hereditary hemochromatosis and in their first-degree relatives
-
Elmberg M, Hultcrantz R, Ekbom A, et al. Cancer risk in patients with hereditary hemochromatosis and in their first-degree relatives. Gastroenterology. 2003;125:1733-41.
-
(2003)
Gastroenterology.
, vol.125
, pp. 1733-1741
-
-
Elmberg, M.1
Hultcrantz, R.2
Ekbom, A.3
-
131
-
-
7044222320
-
Iron, hemochromatosis, and hepatocellular carcinoma
-
Kowdley KV. Iron, hemochromatosis, and hepatocellular carcinoma. Gastroenterology. 2004;127(5 Suppl 1):S79-86.
-
(2004)
Gastroenterology.
, vol.127
, Issue.5
, pp. S79-S86
-
-
Kowdley, K.V.1
-
132
-
-
12344253925
-
Relation of hemochromatosis with hepatocellular carcinoma: epidemiology, natural history, pathophysiology, screening, treatment, and prevention
-
Harrison SA, Bacon BR. Relation of hemochromatosis with hepatocellular carcinoma: epidemiology, natural history, pathophysiology, screening, treatment, and prevention. Med Clin North Am. 2005;89:391-409.
-
(2005)
Med Clin North Am.
, vol.89
, pp. 391-409
-
-
Harrison, S.A.1
Bacon, B.R.2
-
133
-
-
0021823718
-
Cohort study of internal malignancy in genetic hemochromatosis and other chronic nonalcoholic liver diseases
-
Bradbear RA, Bain C, Siskind V, et al. Cohort study of internal malignancy in genetic hemochromatosis and other chronic nonalcoholic liver diseases. J Natl Cancer Inst. 1985;75:81-4.
-
(1985)
J Natl Cancer Inst.
, vol.75
, pp. 81-84
-
-
Bradbear, R.A.1
Bain, C.2
Siskind, V.3
-
134
-
-
0026609144
-
Survival and prognostic factors in 212 Italian patients with genetic hemochromatosis
-
Fargion S, Mandelli C, Piperno A, et al. Survival and prognostic factors in 212 Italian patients with genetic hemochromatosis. Hepatology. 1992;15:655-9.
-
(1992)
Hepatology.
, vol.15
, pp. 655-659
-
-
Fargion, S.1
Mandelli, C.2
Piperno, A.3
-
135
-
-
0022368621
-
Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis
-
Niederau C, Fischer R, Sonnenberg A, et al. Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis. N Engl J Med. 1985;313:1256-62.
-
(1985)
N Engl J Med.
, vol.313
, pp. 1256-1262
-
-
Niederau, C.1
Fischer, R.2
Sonnenberg, A.3
-
137
-
-
0036210375
-
Generation and characterization of p53 null transformed hepatic progenitor cells: oval cells give rise to hepatocellular carcinoma
-
Dumble ML, Croager EJ, Yeoh GC, Quail EA. Generation and characterization of p53 null transformed hepatic progenitor cells: oval cells give rise to hepatocellular carcinoma. Carcinogenesis. 2002;23:435-45.
-
(2002)
Carcinogenesis.
, vol.23
, pp. 435-445
-
-
Dumble, M.L.1
Croager, E.J.2
Yeoh, G.C.3
Quail, E.A.4
-
138
-
-
51249111742
-
C-kit inhibition by imatinib mesylate attenuates progenitor cell expansion and inhibits liver tumor formation in mice
-
Knight B, Tirnitz-Parker JE, Olynyk JK. C-kit inhibition by imatinib mesylate attenuates progenitor cell expansion and inhibits liver tumor formation in mice. Gastroenterology. 2008;135:969-79.
-
(2008)
Gastroenterology.
, vol.135
, pp. 969-979
-
-
Knight, B.1
Tirnitz-Parker, J.E.2
Olynyk, J.K.3
-
139
-
-
7744220635
-
MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer
-
Shachaf CM, Kopelman AM, Arvanitis C, et al. MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer. Nature. 2004;431:1112-7.
-
(2004)
Nature.
, vol.431
, pp. 1112-1117
-
-
Shachaf, C.M.1
Kopelman, A.M.2
Arvanitis, C.3
-
140
-
-
9144224804
-
Hepatocellular carcinoma in the thalassaemia syndromes
-
Borgna-Pignatti C, Vergine G, Lombardo T, et al. Hepatocellular carcinoma in the thalassaemia syndromes. Br J Haematol. 2004;124:114-7.
-
(2004)
Br J Haematol.
, vol.124
, pp. 114-117
-
-
Borgna-Pignatti, C.1
Vergine, G.2
Lombardo, T.3
-
141
-
-
0031748209
-
Dietary iron overload as a risk factor for hepatocellular carcinoma in black Africans
-
Mandishona E, MacPhail AP, Gordeuk VR, et al. Dietary iron overload as a risk factor for hepatocellular carcinoma in black Africans. Hepatology. 1998;27:1563-6.
-
(1998)
Hepatology.
, vol.27
, pp. 1563-1566
-
-
Mandishona, E.1
MacPhail, A.P.2
Gordeuk, V.R.3
-
142
-
-
33746565965
-
Chronic iron overload stimulates hepatocyte proliferation and cyclin D1 expression in rodent liver
-
Brown KE, Mathahs MM, Broadhurst KA, Weydert J. Chronic iron overload stimulates hepatocyte proliferation and cyclin D1 expression in rodent liver. Transl Res. 2006;148:55-62.
-
(2006)
Transl Res.
, vol.148
, pp. 55-62
-
-
Brown, K.E.1
Mathahs, M.M.2
Broadhurst, K.A.3
Weydert, J.4
-
143
-
-
0343471371
-
Iron may induce both DNA synthesis and repair in rat hepatocytes stimulated by EGF/pyruvate
-
Chenoufi N, Loreal O, Drenou B, et al. Iron may induce both DNA synthesis and repair in rat hepatocytes stimulated by EGF/pyruvate. J Hepatol. 1997;26:650-8.
-
(1997)
J Hepatol.
, vol.26
, pp. 650-658
-
-
Chenoufi, N.1
Loreal, O.2
Drenou, B.3
-
144
-
-
0025332680
-
Effect of iron and desferoxamine on cell growth and in vitro ferritin synthesis in human hepatoma cell lines
-
Hann HW, Stahlhut MW, Hann CL. Effect of iron and desferoxamine on cell growth and in vitro ferritin synthesis in human hepatoma cell lines. Hepatology. 1990;11:566-9.
-
(1990)
Hepatology.
, vol.11
, pp. 566-569
-
-
Hann, H.W.1
Stahlhut, M.W.2
Hann, C.L.3
-
145
-
-
0035824070
-
Oxidative stress and p53 mutations in the carcinogenesis of iron overload-associated hepatocellular carcinoma
-
Marrogi AJ, Khan MA, van Gijssel HE, et al. Oxidative stress and p53 mutations in the carcinogenesis of iron overload-associated hepatocellular carcinoma. J Natl Cancer Inst. 2001;93:1652-5.
-
(2001)
J Natl Cancer Inst.
, vol.93
, pp. 1652-1655
-
-
Marrogi, A.J.1
Khan, M.A.2
van Gijssel, H.E.3
-
146
-
-
0032990244
-
p53 Mutations in British patients with hepatocellular carcinoma: clustering in genetic hemochromatosis
-
Vautier G, Bomford AB, Portmann BC, et al. p53 Mutations in British patients with hepatocellular carcinoma: clustering in genetic hemochromatosis. Gastroenterology. 1999;117:154-60.
-
(1999)
Gastroenterology.
, vol.117
, pp. 154-160
-
-
Vautier, G.1
Bomford, A.B.2
Portmann, B.C.3
-
147
-
-
34548675357
-
Antiproliferative and apoptotic effects in rat and human hepatoma cell cultures of the orally active iron chelator ICL670 compared to CP20: a possible relationship with polyamine metabolism
-
Lescoat G, Chantrel-Groussard K, Pasdeloup N, et al. Antiproliferative and apoptotic effects in rat and human hepatoma cell cultures of the orally active iron chelator ICL670 compared to CP20: a possible relationship with polyamine metabolism. Cell Prolif. 2007;40:755-67.
-
(2007)
Cell Prolif.
, vol.40
, pp. 755-767
-
-
Lescoat, G.1
Chantrel-Groussard, K.2
Pasdeloup, N.3
-
148
-
-
35848936696
-
Overexpression of myocyte enhancer factor 2 and histone hyperacetylation in hepatocellular carcinoma
-
Bai X, Wu L, Liang T, et al. Overexpression of myocyte enhancer factor 2 and histone hyperacetylation in hepatocellular carcinoma. J Cancer Res Clin Oncol. 2008;134:83-91.
-
(2008)
J Cancer Res Clin Oncol.
, vol.134
, pp. 83-91
-
-
Bai, X.1
Wu, L.2
Liang, T.3
-
149
-
-
2142853611
-
Role of hepatic stellate cells in the angiogenesis of hepatoma
-
Jung JO, Gwak GY, Lim YS, Kim CY, Lee HS. Role of hepatic stellate cells in the angiogenesis of hepatoma. Korean J Gastroenterol. 2003;42:142-8.
-
(2003)
Korean J Gastroenterol.
, vol.42
, pp. 142-148
-
-
Jung, J.O.1
Gwak, G.Y.2
Lim, Y.S.3
Kim, C.Y.4
Lee, H.S.5
-
150
-
-
33751009660
-
Upregulation of the tumor suppressor gene menin in hepatocellular carcinomas and its significance in fibrogenesis
-
Zindy PJ, L'Helgoualc'h A, Bonnier D, et al. Upregulation of the tumor suppressor gene menin in hepatocellular carcinomas and its significance in fibrogenesis. Hepatology. 2006;44:1296-307.
-
(2006)
Hepatology.
, vol.44
, pp. 1296-1307
-
-
Zindy, P.J.1
L'Helgoualc'h, A.2
Bonnier, D.3
-
151
-
-
0029882435
-
Rat liver ferritin selectively inhibits expression of alpha-smooth muscle actin in cultured rat lipocytes
-
Ramm GA, Britton RS, O'Neill R, Kohn HD, Bacon BR. Rat liver ferritin selectively inhibits expression of alpha-smooth muscle actin in cultured rat lipocytes. Am J Physiol. 1996;270:G370-5.
-
(1996)
Am J Physiol.
, vol.270
, pp. G370-G375
-
-
Ramm, G.A.1
Britton, R.S.2
O'Neill, R.3
Kohn, H.D.4
Bacon, B.R.5
-
152
-
-
0030982967
-
Evidence that "myofibroblast-like" cells are the cellular source of capsular collagen in hepatocellular carcinoma
-
Ooi LP, Crawford DH, Gotley DC, et al. Evidence that "myofibroblast-like" cells are the cellular source of capsular collagen in hepatocellular carcinoma. J Hepatol. 1997;26:798-807.
-
(1997)
J Hepatol.
, vol.26
, pp. 798-807
-
-
Ooi, L.P.1
Crawford, D.H.2
Gotley, D.C.3
-
153
-
-
0035042301
-
Role of myofibroblasts in tumour encapsulation of hepatocellular carcinoma in haemochromatosis
-
Bridle KR, Crawford DH, Powell LW, Ramm GA. Role of myofibroblasts in tumour encapsulation of hepatocellular carcinoma in haemochromatosis. Liver. 2001;21:96-104.
-
(2001)
Liver.
, vol.21
, pp. 96-104
-
-
Bridle, K.R.1
Crawford, D.H.2
Powell, L.W.3
Ramm, G.A.4
-
154
-
-
33845420396
-
The role of cytokines in hepatocellular carcinoma
-
Budhu A, Wang XW. The role of cytokines in hepatocellular carcinoma. J Leukoc Biol. 2006;80:1197-213.
-
(2006)
J Leukoc Biol.
, vol.80
, pp. 1197-1213
-
-
Budhu, A.1
Wang, X.W.2
-
156
-
-
63949086950
-
The immunosuppressive tumor microenvironment in hepatocellular carcinoma
-
Pang YL, Zhang HG, Peng JR, et al. The immunosuppressive tumor microenvironment in hepatocellular carcinoma. Cancer Immunol Immunother. 2009;58(6):887-86.
-
(2009)
Cancer Immunol Immunother.
, vol.58
, Issue.6
, pp. 886-887
-
-
Pang, Y.L.1
Zhang, H.G.2
Peng, J.R.3
-
157
-
-
55249097842
-
Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients
-
Cai L, Zhang Z, Zhou L, et al. Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients. Clin Immunol. 2008;129:428-37.
-
(2008)
Clin Immunol.
, vol.129
, pp. 428-437
-
-
Cai, L.1
Zhang, Z.2
Zhou, L.3
-
158
-
-
0036893626
-
Peripheral lymphocytes and intracellular cytokines in C282Y homozygous hemochromatosis patients
-
Fabio G, Zarantonello M, Mocellin C, et al. Peripheral lymphocytes and intracellular cytokines in C282Y homozygous hemochromatosis patients. J Hepatol. 2002;37:753-61.
-
(2002)
J Hepatol.
, vol.37
, pp. 753-761
-
-
Fabio, G.1
Zarantonello, M.2
Mocellin, C.3
-
159
-
-
0026584553
-
Effect of transferrin, lactoferrin and chelated iron on human T-lymphocytes
-
Djeha A, Brock JH. Effect of transferrin, lactoferrin and chelated iron on human T-lymphocytes. Br J Haematol. 1992;80:235-41.
-
(1992)
Br J Haematol.
, vol.80
, pp. 235-241
-
-
Djeha, A.1
Brock, J.H.2
-
161
-
-
0023803172
-
Iron inhibits the nonspecific tumoricidal activity of macrophages. A possible contributory mechanism for neoplasia in hemochromatosis
-
Green R, Esparza I, Schreiber R. Iron inhibits the nonspecific tumoricidal activity of macrophages. A possible contributory mechanism for neoplasia in hemochromatosis. Ann N Y Acad Sci. 1988;526:301-9.
-
(1988)
Ann N Y Acad Sci.
, vol.526
, pp. 301-309
-
-
Green, R.1
Esparza, I.2
Schreiber, R.3
-
163
-
-
0019434645
-
Iron and the sex difference in heart disease risk
-
Sullivan JL. Iron and the sex difference in heart disease risk. Lancet. 1981;1:1293-4.
-
(1981)
Lancet.
, vol.1
, pp. 1293-1294
-
-
Sullivan, J.L.1
-
164
-
-
0026800818
-
High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men
-
Salonen JT, Nyyssonen K, Korpela H, et al. High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men. Circulation. 1992;86:803-11.
-
(1992)
Circulation.
, vol.86
, pp. 803-811
-
-
Salonen, J.T.1
Nyyssonen, K.2
Korpela, H.3
-
165
-
-
33645230958
-
Serum ferritin, cardiovascular risk factors and ischaemic heart diseases: a prospective analysis in the SU.VI.MAX (SUpplementation en VItamines et mineraux AntioXydants) cohort
-
Galan P, Noisette N, Estaquio C, et al. Serum ferritin, cardiovascular risk factors and ischaemic heart diseases: a prospective analysis in the SU.VI.MAX (SUpplementation en VItamines et mineraux AntioXydants) cohort. Public Health Nutr. 2006;9:70-4.
-
(2006)
Public Health Nutr.
, vol.9
, pp. 70-74
-
-
Galan, P.1
Noisette, N.2
Estaquio, C.3
-
166
-
-
0029938109
-
Iron and heart disease: the epidemiologic data
-
Sempos CT, Looker AC, Gillum RF. Iron and heart disease: the epidemiologic data. Nutr Rev. 1996;54:73-84.
-
(1996)
Nutr Rev.
, vol.54
, pp. 73-84
-
-
Sempos, C.T.1
Looker, A.C.2
Gillum, R.F.3
-
167
-
-
0024565931
-
The iron paradigm of ischemic heart disease
-
Sullivan JL. The iron paradigm of ischemic heart disease. Am Heart J. 1989;117:1177-88.
-
(1989)
Am Heart J.
, vol.117
, pp. 1177-1188
-
-
Sullivan, J.L.1
-
168
-
-
0029848123
-
The iron hypothesis -does iron cause atherosclerosis?
-
Meyers DG. The iron hypothesis -does iron cause atherosclerosis? Clin Cardiol. 1996;19:925-9.
-
(1996)
Clin Cardiol.
, vol.19
, pp. 925-929
-
-
Meyers, D.G.1
-
169
-
-
0036206226
-
Body iron stores and coronary heart disease
-
Ma J, Stampfer MJ. Body iron stores and coronary heart disease. Clin Chem. 2002;48:601-3.
-
(2002)
Clin Chem.
, vol.48
, pp. 601-603
-
-
Ma, J.1
Stampfer, M.J.2
-
170
-
-
0027323409
-
High stored iron and the risk of ischemic heart disease
-
Walker AR, Walker BF, Labadarios D. High stored iron and the risk of ischemic heart disease. Circulation. 1993;88:807-8.
-
(1993)
Circulation.
, vol.88
, pp. 807-808
-
-
Walker, A.R.1
Walker, B.F.2
Labadarios, D.3
-
172
-
-
0025711619
-
Risk factors for coronary heart disease in the Indians of Durban
-
Seedat YK, Mayet FG, Khan S, Somers SR, Joubert G. Risk factors for coronary heart disease in the Indians of Durban. S Afr Med J. 1990;78:447-54.
-
(1990)
S Afr Med J.
, vol.78
, pp. 447-454
-
-
Seedat, Y.K.1
Mayet, F.G.2
Khan, S.3
Somers, S.R.4
Joubert, G.5
-
173
-
-
0037291356
-
Ageing exacerbates the cardiotoxicity of hydrogen peroxide through the Fenton reaction in rats
-
Tanguy S, de Leiris J, Besse S, Boucher F. Ageing exacerbates the cardiotoxicity of hydrogen peroxide through the Fenton reaction in rats. Mech Ageing Dev. 2003;124:229-35.
-
(2003)
Mech Ageing Dev.
, vol.124
, pp. 229-235
-
-
Tanguy, S.1
de Leiris, J.2
Besse, S.3
Boucher, F.4
-
174
-
-
0025059610
-
Role of iron on membrane phospholipid breakdown in ischemic-reperfused rat heart
-
Liu XK, Prasad MR, Engelman RM, Jones RM, Das DK. Role of iron on membrane phospholipid breakdown in ischemic-reperfused rat heart. Am J Physiol. 1990;259:H1101-1107.
-
(1990)
Am J Physiol.
, vol.259
, pp. H1101-H1107
-
-
Liu, X.K.1
Prasad, M.R.2
Engelman, R.M.3
Jones, R.M.4
Das, D.K.5
-
175
-
-
0025607756
-
The effect of desferal on rat heart mitochondrial function, iron content, and xanthine dehydrogenase/oxidase conversion during ischemia-reperfusion
-
van Jaarsveld H, Potgieter GM, Kuyl JM, Barnard HC, Barnard SP. The effect of desferal on rat heart mitochondrial function, iron content, and xanthine dehydrogenase/oxidase conversion during ischemia-reperfusion. Clin Biochem. 1990;23:509-13.
-
(1990)
Clin Biochem.
, vol.23
, pp. 509-513
-
-
van Jaarsveld, H.1
Potgieter, G.M.2
Kuyl, J.M.3
Barnard, H.C.4
Barnard, S.P.5
-
176
-
-
33745633060
-
Reduction of infarct size in a rat model of regional myocardial ischemia and reperfusion by the synthetic peptide DAHK
-
Bar-Or D, McDonald MC, Thiemermann C. Reduction of infarct size in a rat model of regional myocardial ischemia and reperfusion by the synthetic peptide DAHK. Crit Care Med. 2006;34:1955-9.
-
(2006)
Crit Care Med.
, vol.34
, pp. 1955-1959
-
-
Bar-Or, D.1
McDonald, M.C.2
Thiemermann, C.3
-
177
-
-
0026649212
-
Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions
-
Smith C, Mitchinson MJ, Aruoma OI, Halliwell B. Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions. Biochem J. 1992;286:901-5.
-
(1992)
Biochem J.
, vol.286
, pp. 901-905
-
-
Smith, C.1
Mitchinson, M.J.2
Aruoma, O.I.3
Halliwell, B.4
-
178
-
-
0003714337
-
Elemental changes in atherosclerotic lesions using nuclear microscopy
-
Thong PS, Selley M, Watt F. Elemental changes in atherosclerotic lesions using nuclear microscopy. Cell Mol Biol. 1996;42:103-10.
-
(1996)
Cell Mol Biol.
, vol.42
, pp. 103-110
-
-
Thong, P.S.1
Selley, M.2
Watt, F.3
-
179
-
-
34548429748
-
Macrophage iron, hepcidin, and atherosclerotic plaque stability
-
Sullivan JL. Macrophage iron, hepcidin, and atherosclerotic plaque stability. Exp Biol Med (Maywood). 2007;232:1014-20.
-
(2007)
Exp Biol Med (Maywood).
, vol.232
, pp. 1014-1020
-
-
Sullivan, J.L.1
-
180
-
-
55649092852
-
Heart protection by ischemic preconditioning: a novel pathway initiated by iron and mediated by ferritin
-
Chevion M, Leibowitz S, Aye NN, et al. Heart protection by ischemic preconditioning: a novel pathway initiated by iron and mediated by ferritin. J Mol Cell Cardiol. 2008;45:839-45.
-
(2008)
J Mol Cell Cardiol.
, vol.45
, pp. 839-845
-
-
Chevion, M.1
Leibowitz, S.2
Aye, N.N.3
-
181
-
-
0842264960
-
Myocardial ferritin content is closely related to the degree of ischaemia
-
Loncar R, Flesche CW, Deussen A. Myocardial ferritin content is closely related to the degree of ischaemia. Acta Physiol Scand. 2004;180:21-8.
-
(2004)
Acta Physiol Scand.
, vol.180
, pp. 21-28
-
-
Loncar, R.1
Flesche, C.W.2
Deussen, A.3
-
182
-
-
25144437020
-
Serum ferritin in stroke: a marker of increased body iron stores or stroke severity?
-
Millerot E, Prigent-Tessier AS, Bertrand NM, et al. Serum ferritin in stroke: a marker of increased body iron stores or stroke severity? J Cereb Blood Flow Metab. 2005;25:1386-93.
-
(2005)
J Cereb Blood Flow Metab.
, vol.25
, pp. 1386-1393
-
-
Millerot, E.1
Prigent-Tessier, A.S.2
Bertrand, N.M.3
-
183
-
-
33746224376
-
Pro-inflammatory states and IGF-I level in ischemic heart disease with low or high serum iron
-
Lee SD, Huang CY, Shu WT, et al. Pro-inflammatory states and IGF-I level in ischemic heart disease with low or high serum iron. Clin Chim Acta. 2006;370:50-6.
-
(2006)
Clin Chim Acta.
, vol.370
, pp. 50-56
-
-
Lee, S.D.1
Huang, C.Y.2
Shu, W.T.3
-
184
-
-
0023626933
-
Improvement of postischemic myocardial function and metabolism induced by administration of deferoxamine at the time of reflow: the role of iron in the pathogenesis of reperfusion injury
-
Ambrosio G, Zweier JL, Jacobus WE, Weisfeldt ML, Flaherty JT. Improvement of postischemic myocardial function and metabolism induced by administration of deferoxamine at the time of reflow: the role of iron in the pathogenesis of reperfusion injury. Circulation. 1987;76:906-15.
-
(1987)
Circulation.
, vol.76
, pp. 906-915
-
-
Ambrosio, G.1
Zweier, J.L.2
Jacobus, W.E.3
Weisfeldt, M.L.4
Flaherty, J.T.5
-
185
-
-
33845680256
-
Dexrazoxane prevents myocardial ischemia/reperfusion-induced oxidative stress in the rat heart
-
Ramu E, Korach A, Houminer E, et al. Dexrazoxane prevents myocardial ischemia/reperfusion-induced oxidative stress in the rat heart. Cardiovasc Drugs Ther. 2006;20:343-8.
-
(2006)
Cardiovasc Drugs Ther.
, vol.20
, pp. 343-348
-
-
Ramu, E.1
Korach, A.2
Houminer, E.3
-
186
-
-
0037232582
-
Deferoxamine enhances neovascularization and recovery of ischemic skeletal muscle in an experimental sheep model
-
Chekanov VS, Nikolaychik V, Maternowski MA, et al. Deferoxamine enhances neovascularization and recovery of ischemic skeletal muscle in an experimental sheep model. Ann Thorac Surg. 2003;75:184-9.
-
(2003)
Ann Thorac Surg.
, vol.75
, pp. 184-189
-
-
Chekanov, V.S.1
Nikolaychik, V.2
Maternowski, M.A.3
-
187
-
-
33646351076
-
Role of L-type Ca2+ channels in iron transport and ironoverload cardiomyopathy
-
Oudit GY, Trivieri MG, Khaper N, Liu PP, Backx PH. Role of L-type Ca2+ channels in iron transport and ironoverload cardiomyopathy. J Mol Med. 2006;84:349-64.
-
(2006)
J Mol Med.
, vol.84
, pp. 349-364
-
-
Oudit, G.Y.1
Trivieri, M.G.2
Khaper, N.3
Liu, P.P.4
Backx, P.H.5
-
188
-
-
0141461407
-
L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy
-
Oudit GY, Sun H, Trivieri MG, et al. L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy. Nat Med. 2003;9:1187-94.
-
(2003)
Nat Med.
, vol.9
, pp. 1187-1194
-
-
Oudit, G.Y.1
Sun, H.2
Trivieri, M.G.3
-
189
-
-
0041421288
-
Dietary iron restriction increases plaque stability in apolipoprotein-e-deficient mice
-
Lee HT, Chiu LL, Lee TS, Tsai HL, Chau LY. Dietary iron restriction increases plaque stability in apolipoprotein-e-deficient mice. J Biomed Sci. 2003;10:510-7.
-
(2003)
J Biomed Sci.
, vol.10
, pp. 510-517
-
-
Lee, H.T.1
Chiu, L.L.2
Lee, T.S.3
Tsai, H.L.4
Chau, L.Y.5
-
190
-
-
15944403231
-
The iron chelator desferrioxamine inhibits atherosclerotic lesion development and decreases lesion iron concentrations in the cholesterol-fed rabbit
-
Minqin R, Rajendran R, Pan N, et al. The iron chelator desferrioxamine inhibits atherosclerotic lesion development and decreases lesion iron concentrations in the cholesterol-fed rabbit. Free Radic Biol Med. 2005;38:1206-11.
-
(2005)
Free Radic Biol Med.
, vol.38
, pp. 1206-1211
-
-
Minqin, R.1
Rajendran, R.2
Pan, N.3
-
191
-
-
0042328308
-
The prevalence of haemochromatosis gene mutations in the west of Scotland and their relation to ischaemic heart disease
-
Campbell S, George DK, Robb SD, et al. The prevalence of haemochromatosis gene mutations in the west of Scotland and their relation to ischaemic heart disease. Heart. 2003;89:1023-6.
-
(2003)
Heart.
, vol.89
, pp. 1023-1026
-
-
Campbell, S.1
George, D.K.2
Robb, S.D.3
-
192
-
-
46349085839
-
HFE C282Y homozygotes have reduced low-density lipoprotein cholesterol: the atherosclerosis risk in communities (ARIC) study
-
Pankow JS, Boerwinkle E, Adams PC, et al. HFE C282Y homozygotes have reduced low-density lipoprotein cholesterol: the atherosclerosis risk in communities (ARIC) study. Transl Res. 2008;152:3-10.
-
(2008)
Transl Res.
, vol.152
, pp. 3-10
-
-
Pankow, J.S.1
Boerwinkle, E.2
Adams, P.C.3
-
193
-
-
0037109598
-
Prevalence of coronary heart disease associated with HFE mutations in adults attending a health appraisal center
-
Waalen J, Felitti V, Gelbart T, Ho NJ, Beutler E. Prevalence of coronary heart disease associated with HFE mutations in adults attending a health appraisal center. Am J Med. 2002;113:472-9.
-
(2002)
Am J Med.
, vol.113
, pp. 472-479
-
-
Waalen, J.1
Felitti, V.2
Gelbart, T.3
Ho, N.J.4
Beutler, E.5
-
194
-
-
0037704226
-
HFE mutation and dietary iron content interact to increase ischemia/reperfusion injury of the heart in mice
-
Turoczi T, Jun L, Cordis G, et al. HFE mutation and dietary iron content interact to increase ischemia/reperfusion injury of the heart in mice. Circ Res. 2003;92:1240-6.
-
(2003)
Circ Res.
, vol.92
, pp. 1240-1246
-
-
Turoczi, T.1
Jun, L.2
Cordis, G.3
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