Cytoglobin/STAP, its unique localization in splanchnic fibroblast-like cells and function in organ fibrogenesis

Laboratory Investigation

Volumn 84, Issue 1, 2004, Pages 91-101

  Nakatani, Kazuki ^a   Okuyama, Hiroaki ^b   Shimahara, Yasuyuki ^b   Saeki, Shigeru ^c   Kim, Dong Ho ^c   Nakajima, Yuji ^a   Seki, Shuichi ^a   Kawada, Norifumi ^a   Yoshizato, Katsutoshi ^d,e  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c Osaka Prefecture University   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Collagen 1(1); Fibroblasts; NIH 3T3 cells; PDGF; Stellate cells; TGF ; Vitamin A

Indexed keywords

COLLAGEN TYPE 1; GLOBIN; HEMOGLOBIN; HEMOPROTEIN; MESSENGER RNA; MYOGLOBIN; PROTEIN CYTOGLOBIN; PROTEIN NEUROGLOBIN; PROTEIN STAP; RETINOL; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; PEROXIDASE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; PLATELET-DERIVED GROWTH FACTOR BB; STAAP PROTEIN, RAT; TGFB1 PROTEIN, MOUSE; TGFB1 PROTEIN, RAT; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; BLOOD CELL; CELL CULTURE; CELL LINEAGE; CELL STRAIN 3T3; CONTROLLED STUDY; ENDOTHELIUM CELL; EPITHELIUM CELL; FIBROBLAST; FIBROGENESIS; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; SKIN FIBROBLAST; ANIMAL; CHEMICALLY INDUCED DISORDER; CHRONIC DISEASE; DISEASE MODEL; DRUG EFFECT; ENZYMOLOGY; FIBROSIS; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC TRANSFECTION; GENETICS; GERMFREE ANIMAL; KIDNEY DISEASE; KUPFFER CELL; METABOLISM; MOUSE; PANCREAS; PANCREATITIS; PATHOLOGY; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE; WISTAR RAT;

ANIMALS; BIOLOGICAL MARKERS; CHRONIC DISEASE; COLLAGEN TYPE I; DISEASE MODELS, ANIMAL; FIBROSIS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GLOBINS; HEMEPROTEINS; KIDNEY DISEASES; KUPFFER CELLS; MALE; MICE; NIH 3T3 CELLS; PANCREAS; PANCREATITIS; PEROXIDASES; PLATELET-DERIVED GROWTH FACTOR; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RNA, MESSENGER; SPECIFIC PATHOGEN-FREE ORGANISMS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; VITAMIN A;

EID: 85047691361     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.3700013     Document Type: Article

References (51)

1. Kawada N, Kristensen DB, Asahina K, et al. Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells. J Biol Chem 2001;276:25318-25323.
2. Burmester T, Ebner B, Weich B, et al. Cytoglobin: a novel globin type ubiquitously expressed in vertebrate tissues. Mol Biol Evol 2002;19:416-421.
3. Pesce A, Bolognesi M, Bocedi A, et al. Neuroglobin and cytoglobin. Fresh blood for the vertebrate globin family. EMBO reports 2002;3:1146-1151.
4. Trent III JT, Hargrove MS. A ubiquitously expressed human hexacoordinate hemoglobin. J Biol Chem 2002;277:19538-19545.
5. Kawada N. The hepatic perisinusoidal stellate cell. Histol Histopathol 1997;12:1069-1080.
6. Asahina K, Kawada N, Kristensen DB, et al. Characterization of human stellate cell activation-associated protein and its expression in human liver. Biochim Biophys Acta 2002;1577:471-475.
7. Yamada E, Hirosawa K. The possible existence of a vitamin A-storing cell system. Cell Struct Funct 1976;1:201-204.
8. Wake K. Perisinusoidal stellate cells (fat-storing cells, interstitial cells, lipocytes), their related structure in and around the liver sinusoids, and vitamin A-storing cells in extrahepatic organs. Int Rev Cytol 1980;66:303-353.
9. Komuro T. Re-evaluation of fibroblasts and fibroblast-like cells. Anat Embryol 1990;182:103-112.
10. Burdmann EA, Andoh TF, Nast CC, et al. Prevention of experimental cyclosporin-induced interstitial fibrosis by losartan and enalapril. Am J Physiol 1995;269:F491-F499.
11. Brenan M, Puklavec M. The MRC OX-62 antigen: a useful marker in the purification of rat veiled cells with the biochemical properties of an integrin. J Exp Med 1992;175:1457-1465.
12. Brissette-Storkus CS, Kettel JC, Whitham TF, et al. Flt-3 ligand (FL) drives differentiation of rat bone marrow-derived dendritic cells expressing OX62 and/or CD161 (NKR-P1). J Leukocyte Biol 2002;71:941-949.
13. Tao LH, Enzan H, Hayashi Y, et al. Appearance of denuded hepatic stellate cells and their subsequent myofibroblast-like transformation during the early stage of biliary fibrosis in the rat. Med Electron Microsc 2000;33:217-230.
14. Vannucchi MG, Corsani L, Faussone-Pellegrini MS. Substance P immunoreactive nerves and interstitial cells of Cajal in the rat and guinea-pig ileum. A histochemical and quantitative study. Neurosci Lett 1999;268:49-52.
15. Nishihara E, Nagayama Y, Inoue S, et al. Ontogenetic changes in the expression of estrogen receptor alpha and beta in rat pituitary gland detected by immunohistochemistry. Endocrinology 2000;141:615-620.
16. Nakatani K, Seki S, Kawada N, et al. Expression of SPARC by activated hepatic stellate cells and its correlation with the stages of fibrogenesis in human chronic hepatitis. Virchows Archiv 2002;441:466-474.
17. Nakatani K, Seki S, Kawada N, et al. Expression of neural cell adhesion molecule (N-CAM) in perisinusoidal stellate cells of the human liver. Cell Tissue Res 1996;283:159-165.
18. Kobayashi S, Seki S, Kawada N, et al. Apoptosis of T cells in the hepatic fibrotic tissue of the rat: a possible inducing role of hepatic myofibroblast-like cells. Cell Tissue Res 2003;311:353-364.
19. Ikeda K, Wakahara T, Wang YQ, et al. In vitro migratory potential of rat quiescent hepatic stellate cells and its augmentation by cell activation. Hepatology 1999;29:1760-1767.
20. Le Hir M, Kaissling B. Distribution of 5'-nucleotidase in the renal interstitium of the rat. Cell Tissue Res 1989;258:177-182.
21. Kaissling B, Hegyi I, Loffing J, et al. Morphology of interstitial cells in the healthy kidney. Anat Embryol 1996;193:303-318.
22. Tisher CC, Madsen KM. Anatomy of the kidney, In: Brenner BM (ed). Brenner and Rector's the Kidney, 6th edn W.B. Saunders: Philadelphia, 2000, 3-67.
23. Kawada N, Kuroki T, Kobayashi K, et al. Expression of heat-shock protein 47 in mouse liver. Cell Tissue Res 1996;284:341-346.
24. Nagata K. Hsp47: a collagen-specific molecular chaperone. Trends Biochem Sci 1996;21:22-26.
25. Sogawa M, Matsumoto T, Yamagami H, et al. A murine model of granulomatous colitis with mesenteric lymphadenitis induced by mycobacterial cord factor. Virchows Arch 2003;442:151-158.
26. Yamamoto T, Yamamoto K, Kawasaki K, et al. Immunoelectron microscopic demonstration of Thy-1 antigen on the surfaces of mesangial cells in the rat glomerulus. Nephron 1986;43:293-298.
27. Yaoita E, Yamamoto T, Takashima N, et al. Visceral epithelial cells in rat glomerular cell culture. Eur J Cell Biol 1995;67:136-144.
28. Ardaillou R, Ronco P, Rondeau E, et al. Biology of renal cells in culture, In: Brenner BM (ed) Brenner and Rector's the Kidney, 6th edn. W.B. Saunders: Philadelphia, 2000, 93-191.
29. Skalli O, Ropraz P, Trzeciak A, et al. A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol 1986;103:2787-2796.
30. Komuro T, Seki K, Horiguchi K. Ultrastructural characterization of the interstitial cells of Cajal. Arch Histol Cytol 199;62:295-316.
31. Ohashi K, Kim JH, Kara H, et al. WBN/Kob rats. A new spontaneously occurring model of chronic pancreatitis. Int J Pancreatol 1990;6:231-247.
32. Kakinuma C, Suda K, Shibutani Y. Histopathological and biochemical studies on pancreatic fibrosis in WBN/Kob rats. Virchows Arch 1999;434:83-89.
33. Pinzani M, Marra F. Cytokine receptors and signaling in hepatic stellate cells. Semin Liver Dis 2001;21:397-416.
34. Kristensen DB, Kawada N, Imamura K, et al. Proteome analysis of rat hepatic stellate cells. Hepatology 2000;32:268-277.
35. Apte MV, Haber PS, Applegate TL, et al. Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture. Gut 1998;43:128-133.
36. Bachem MG, Schneider E, Gross H, et al. Identification, culture, and characterization of pancreatic stellate cells in rats and humans. Gastroenterology 1998;115:421-432.
37. Nagy NE, Holven KB, Roos N, et al. Storage of vitamin A in extrahepatic stellate cells in normal rats. J Lipid Res 1997;38:645-658.
38. Kusumoto Y, Fujita T. Vitamin A uptake cells distributed in the liver and other organs of the rat. Arch Histol Jap 1977;40:121-136.
39. Yamamoto M, Enzan H, Hara H, et al. Fluorescence and electron microscopic studies on the perivascular mesenchymal cells and fibroblasts after vitamin A administration. Acta Pathol Jap 1978;28:513-521.
40. Wake K. The sternzellen of von Kuppfer-after 106 years, In: Knook DL, Wisse E, (eds) Sinusoidal Liver Cells. Elsevier Biomedical Press: The Netherlands, 1982, 1-12.
41. Wake K. One hundred years of sinusoidal cells in the liver. Acta Anat Nippon 1997;72:407-423.
42. Bauer P, Wake K. Mesangial cells of the lamprey, Lampetra japonica, store vitamin A. Arch Histol Cytol 1996;59:71-78.
43. Haber PS, Keogh GW, Apte MV, et al. Activation of pancreatic stellate cells in human and experimental pancreatic fibrosis. Am J Pathol 1999;155:1087-1095.
44. Schürch W, Seemayer TA, Gabbiani G. Myofibroblast, In: Sternberg SS (ed). Histology for Pathologists, 2nd edn. Lippincott-Raven Publishers: Philadelphia, 1997, pp 129-165.
45. Badid C, Mounier N, Costa AMA, et al. Role of myofibroblasts during normal tissue repair and excessive scarring: interest of their assessment in nephropathies. Histol Histopathol 2000;15:269-280.
46. Zeisberg M, Strutz F, Müller GA. Role of fibroblast activation in inducing interstitial fibrosis. J Nephrol 2000;13:S111-S120.
47. Geuens E, Brouns I, Flamez D, et al. A globin in the nucleus. J Biol Chem 2000;278:30417-30420.
48. Ridley AJ, Hall A. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 1992;70:389-399.
49. Luttrell LM. Big G, little G: G proteins and actin cytoskeletal reorganization. Mol Cell 2002;9:1152-1154.
50. Olivo C, Vanni C, Mancini P, et al. Distinct involvement of cdc42 and RhoA GTPases in actin organization and cell shape in untransformed and Dbl oncogene transformed NIH3T3 cells. Oncogene 2000;19:1428-1436.
51. Verma A, Davis GE, Ihler GM. Formation of stress fibres in human endothelial cells infected with Bartonella bacilliformis is associated with altered morphology, impaired migration and defects in cell morphogenesis. Cell Microbiol 2001;3:169-180.