-
1
-
-
0032955556
-
Molecular medicine and hemochromatosis: At the crossroads
-
Bacon BR, Powell LW, Adams PC, Kresina TF, Hoofnagle JH. Molecular medicine and hemochromatosis: at the crossroads. Gastroenterology. 1999;116:193-207.
-
(1999)
Gastroenterology
, vol.116
, pp. 193-207
-
-
Bacon, B.R.1
Powell, L.W.2
Adams, P.C.3
Kresina, T.F.4
Hoofnagle, J.H.5
-
2
-
-
0037132786
-
Penetrance of 845G→A (C282Y) HFE hereditary haemochromatosis mutation in the USA
-
Beutler E, Felitti VJ, Koziol JA, Ho NJ, Gelbart T. Penetrance of 845G→A (C282Y) HFE hereditary haemochromatosis mutation in the USA. Lancet. 2002;359:211-218.
-
(2002)
Lancet
, vol.359
, pp. 211-218
-
-
Beutler, E.1
Felitti, V.J.2
Koziol, J.A.3
Ho, N.J.4
Gelbart, T.5
-
3
-
-
0033517343
-
A population-based study of the clinical expression of the hemochromatosis gene
-
Olynyk JK, Cullen DJ, Aquilia S, Rossi E, Summerville L, Powell LW. A population-based study of the clinical expression of the hemochromatosis gene. N Engl J Med. 1999;341:718-724.
-
(1999)
N Engl J Med
, vol.341
, pp. 718-724
-
-
Olynyk, J.K.1
Cullen, D.J.2
Aquilia, S.3
Rossi, E.4
Summerville, L.5
Powell, L.W.6
-
4
-
-
20244372858
-
Hemochromaotis and iron-overload screening in a racially diverse population
-
Adams PC, Reboussin DM, Barton JC, et al. Hemochromaotis and iron-overload screening in a racially diverse population. N Engl J Med. 2005;352:1769-1778.
-
(2005)
N Engl J Med
, vol.352
, pp. 1769-1778
-
-
Adams, P.C.1
Reboussin, D.M.2
Barton, J.C.3
-
5
-
-
22544455045
-
Use of community screening to prevent HFE-associated hereditary haemochromatosis
-
Delatycki MB, Allen KJ, Nisselle AE, et al. Use of community screening to prevent HFE-associated hereditary haemochromatosis. Lancet. 2005;366:314-316.
-
(2005)
Lancet
, vol.366
, pp. 314-316
-
-
Delatycki, M.B.1
Allen, K.J.2
Nisselle, A.E.3
-
6
-
-
0029913626
-
Long-term survival in patients with hereditary hemochromatosis
-
Niederau C, Fischer R, Purschel A, Stremmel W, Haussinger D, Strohmeyer G. Long-term survival in patients with hereditary hemochromatosis. Gastroenterology. 1996;110:1107-1119.
-
(1996)
Gastroenterology
, vol.110
, pp. 1107-1119
-
-
Niederau, C.1
Fischer, R.2
Purschel, A.3
Stremmel, W.4
Haussinger, D.5
Strohmeyer, G.6
-
7
-
-
17944369464
-
Screening for hemochromatosis: High prevalence and low morbidity in an unselected population of 65,238 persons
-
Asberg A, Hveem K, Thorstensen K, et al. Screening for hemochromatosis: high prevalence and low morbidity in an unselected population of 65,238 persons. Scand J Gastroenterol. 2001;36:1108-1115.
-
(2001)
Scand J Gastroenterol
, vol.36
, pp. 1108-1115
-
-
Asberg, A.1
Hveem, K.2
Thorstensen, K.3
-
8
-
-
3042832786
-
Frequency of the C282Y and H63D mutations of the hemochromatosis gene (HFE) in 2501 ethnic Danes
-
Milman N, Pedersen P, Ovesen L, Melsen GV, Fenger K. Frequency of the C282Y and H63D mutations of the hemochromatosis gene (HFE) in 2501 ethnic Danes. Ann Hematol. 2004;83:654-657.
-
(2004)
Ann Hematol
, vol.83
, pp. 654-657
-
-
Milman, N.1
Pedersen, P.2
Ovesen, L.3
Melsen, G.V.4
Fenger, K.5
-
9
-
-
0034707120
-
Disease-related conditions in relatives of patients with hemochromatosis
-
Bulaj ZJ, Ajoika RS, Phillips JD, et al. Disease-related conditions in relatives of patients with hemochromatosis. N Engl J Med. 2000;343:1529-1535.
-
(2000)
N Engl J Med
, vol.343
, pp. 1529-1535
-
-
Bulaj, Z.J.1
Ajoika, R.S.2
Phillips, J.D.3
-
10
-
-
0034056799
-
Population screening for hemochromatosis: A comparison of unbound iron-binding capacity, transferrin saturation, and C282Y genotyping in 5,211 voluntary blood donors
-
Adams PC, Kertesz AE, McLaren CE, Barr R, Bamford A, Chakrabarti S. Population screening for hemochromatosis: a comparison of unbound iron-binding capacity, transferrin saturation, and C282Y genotyping in 5,211 voluntary blood donors. Hepatology. 2000;31:1160-1164.
-
(2000)
Hepatology
, vol.31
, pp. 1160-1164
-
-
Adams, P.C.1
Kertesz, A.E.2
McLaren, C.E.3
Barr, R.4
Bamford, A.5
Chakrabarti, S.6
-
11
-
-
0030341599
-
Population screening for haemochromatosis: Expectations based on a study of relatives of symptomatic probands
-
Bradley LA, Haddow JE, Palomaki GE. Population screening for haemochromatosis: expectations based on a study of relatives of symptomatic probands. J Med Screen. 1996;3:171-177.
-
(1996)
J Med Screen
, vol.3
, pp. 171-177
-
-
Bradley, L.A.1
Haddow, J.E.2
Palomaki, G.E.3
-
13
-
-
0021215227
-
Diagnosis of hemochromatosis in young subjects: Predictive accuracy of biochemical screening tests
-
Bassett ML, Halliday JW, Ferris RA, Powell LW. Diagnosis of hemochromatosis in young subjects: predictive accuracy of biochemical screening tests. Gastroenterology. 1984;87:628-633.
-
(1984)
Gastroenterology
, vol.87
, pp. 628-633
-
-
Bassett, M.L.1
Halliday, J.W.2
Ferris, R.A.3
Powell, L.W.4
-
15
-
-
0022656390
-
Value of hepatic iron measurements in early haemochromatosis and determination of the critical iron concentration associated with fibrosis
-
Bassett ML, Halliday JW, Powell LW. Value of hepatic iron measurements in early haemochromatosis and determination of the critical iron concentration associated with fibrosis. Hepatology. 1986;6:24-29.
-
(1986)
Hepatology
, vol.6
, pp. 24-29
-
-
Bassett, M.L.1
Halliday, J.W.2
Powell, L.W.3
-
17
-
-
0002519237
-
Iron storage disease
-
Mac-Sween RM, Anthony PP, Scheuer PJ, eds. Edinburgh, Scotland: Churchill Livingstone
-
Searle JW, Kerr JFR, Halliday JW, Powell LW. Iron storage disease. In: Mac-Sween RM, Anthony PP, Scheuer PJ, eds. Pathology of the Liver. 2nd ed. Edinburgh, Scotland: Churchill Livingstone; 1987:257-272.
-
(1987)
Pathology of the Liver. 2nd Ed.
, pp. 257-272
-
-
Searle, J.W.1
Kerr, J.F.R.2
Halliday, J.W.3
Powell, L.W.4
-
18
-
-
0026072529
-
Classification of chronic viral hepatitis: A need for reassessment
-
Scheuer PJ. Classification of chronic viral hepatitis: a need for reassessment. J Hepatol. 1991;13:372-374.
-
(1991)
J Hepatol
, vol.13
, pp. 372-374
-
-
Scheuer, P.J.1
-
19
-
-
0036163634
-
Excess alcohol greatly increases the prevalence of cirrhosis in hereditary hemochromatosis
-
Fletcher LM, Dixon JL, Purdie DM, Powell LW, Crawford DH. Excess alcohol greatly increases the prevalence of cirrhosis in hereditary hemochromatosis. Gastroenterology. 2002;122:281-289.
-
(2002)
Gastroenterology
, vol.122
, pp. 281-289
-
-
Fletcher, L.M.1
Dixon, J.L.2
Purdie, D.M.3
Powell, L.W.4
Crawford, D.H.5
-
20
-
-
0015804314
-
Serum ferritin concentration and iron stores in normal subjects
-
Walters GO, Miller FM, Worwood M. Serum ferritin concentration and iron stores in normal subjects. J Clin Pathol. 1973;26:770-772.
-
(1973)
J Clin Pathol
, vol.26
, pp. 770-772
-
-
Walters, G.O.1
Miller, F.M.2
Worwood, M.3
-
21
-
-
4244142650
-
Physioanatomic considerations
-
Schiff ER, Sorrell MF, Maddrey WC, eds. Philadelphia, Pa: Lippincott-Raven Publishers
-
Wanless IR. Physioanatomic considerations. In: Schiff ER, Sorrell MF, Maddrey WC, eds. Schiff's Diseases of the Liver. 8th ed. Philadelphia, Pa: Lippincott-Raven Publishers; 1993:3-37.
-
(1993)
Schiff's Diseases of the Liver. 8th Ed.
, pp. 3-37
-
-
Wanless, I.R.1
-
22
-
-
0003106681
-
Laboratory determinants of iron status
-
Brock JH, Halliday JW, Pippard MJ, Powell LW, eds. London, England: WB Saunders & Co
-
Worwood M. Laboratory determinants of iron status. In: Brock JH, Halliday JW, Pippard MJ, Powell LW, eds. Iron Metabolism in Health and Disease. London, England: WB Saunders & Co; 1994:449-476.
-
(1994)
Iron Metabolism in Health and Disease
, pp. 449-476
-
-
Worwood, M.1
-
23
-
-
0004160326
-
-
Oxford, England: Blackwell Scientific Publications
-
Bothwell TH, Charlton RW, Cook JD, Finch CA. Iron Metabolism in Man. Oxford, England: Blackwell Scientific Publications, 1979:89.
-
(1979)
Iron Metabolism in Man
, pp. 89
-
-
Bothwell, T.H.1
Charlton, R.W.2
Cook, J.D.3
Finch, C.A.4
-
24
-
-
1842579593
-
Hemochromatosis mutations in the general population: Iron overload progression rate
-
Andersen RV, Tybjaerg-Hansen A, Appleyard M, Birgens H, Nordestgaard BG. Hemochromatosis mutations in the general population: iron overload progression rate. Blood. 2004;103:2914-2919.
-
(2004)
Blood
, vol.103
, pp. 2914-2919
-
-
Andersen, R.V.1
Tybjaerg-Hansen, A.2
Appleyard, M.3
Birgens, H.4
Nordestgaard, B.G.5
-
25
-
-
0035678345
-
Clinically overt hereditary hemochromatosis in Denmark 1948-1985: Epidemiology, factors of significance for long-term survival, and causes of death in 179 patients
-
Milman N, Pedersen P, a Steig T, Byg KE, Graudal N, Fenger K. Clinically overt hereditary hemochromatosis in Denmark 1948-1985: epidemiology, factors of significance for long-term survival, and causes of death in 179 patients. Ann Hematol. 2001;80:737-744.
-
(2001)
Ann Hematol
, vol.80
, pp. 737-744
-
-
Milman, N.1
Pedersen, P.2
A Steig, T.3
Byg, K.E.4
Graudal, N.5
Fenger, K.6
-
26
-
-
1442282237
-
Evoluation of untreated hereditary hemochromatosis in the Busselton population: A 17-year study
-
Olynyk JK, Hagan SE, Cullen DJ, Beilby J, Whittall DE. Evoluation of untreated hereditary hemochromatosis in the Busselton population: a 17-year study. Mayo Clin Proc. 2004;79:309-313.
-
(2004)
Mayo Clin Proc
, vol.79
, pp. 309-313
-
-
Olynyk, J.K.1
Hagan, S.E.2
Cullen, D.J.3
Beilby, J.4
Whittall, D.E.5
-
27
-
-
0031030733
-
The relationship between iron overload, clinical symptoms, and age in 410 patients with genetic hemochromatosis
-
Adams PC, Deugnier Y, Moirand R, Brissot P. The relationship between iron overload, clinical symptoms, and age in 410 patients with genetic hemochromatosis. Hepatology. 1997;25:162-166.
-
(1997)
Hepatology
, vol.25
, pp. 162-166
-
-
Adams, P.C.1
Deugnier, Y.2
Moirand, R.3
Brissot, P.4
-
28
-
-
0035124088
-
Is there a threshold of hepatic iron concentration that leads to cirrhosis in C282Y hemochromatosis
-
Adams PC. Is there a threshold of hepatic iron concentration that leads to cirrhosis in C282Y hemochromatosis Am J Gastroenterol. 2001;96:567-569.
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 567-569
-
-
Adams, P.C.1
-
29
-
-
0026058496
-
Confirmation of the efficacy of hepatic tissue iron index in differentiating genetic haemochromatosis from alcoholic liver disease complicated by alcoholic haemosiderosis
-
Sallie RW, Reed WD, Shilkin KB. Confirmation of the efficacy of hepatic tissue iron index in differentiating genetic haemochromatosis from alcoholic liver disease complicated by alcoholic haemosiderosis. Gut. 1991;32:207-210.
-
(1991)
Gut
, vol.32
, pp. 207-210
-
-
Sallie, R.W.1
Reed, W.D.2
Shilkin, K.B.3
-
30
-
-
0141961623
-
Natural history of the C282Y homozygote for the hemochromatosis gene (HFE) with a normal serum ferritin level
-
Yamashita C, Adams PC. Natural history of the C282Y homozygote for the hemochromatosis gene (HFE) with a normal serum ferritin level. Clin Gastroenterol Hepatol. 2003;1:388-391.
-
(2003)
Clin Gastroenterol Hepatol
, vol.1
, pp. 388-391
-
-
Yamashita, C.1
Adams, P.C.2
-
31
-
-
0025146396
-
Factors affecting the concentrations of ferritin in serum in a healthy Australian population
-
Leggett BA, Brown NN, Bryant SJ, Duplock L, Powell LW, Halliday JW. Factors affecting the concentrations of ferritin in serum in a healthy Australian population. Clin Chem. 1990;36:1350-1355.
-
(1990)
Clin Chem
, vol.36
, pp. 1350-1355
-
-
Leggett, B.A.1
Brown, N.N.2
Bryant, S.J.3
Duplock, L.4
Powell, L.W.5
Halliday, J.W.6
-
32
-
-
1642494711
-
Serum ferritin level predicts advanced hepatic fibrosis among U.S. patients with phenotypic hemochromatosis
-
Morrison ED, Brandhagen DJ, Phatak PD, et al. Serum ferritin level predicts advanced hepatic fibrosis among U.S. patients with phenotypic hemochromatosis. Ann Intern Med. 2003;138:627-633.
-
(2003)
Ann Intern Med
, vol.138
, pp. 627-633
-
-
Morrison, E.D.1
Brandhagen, D.J.2
Phatak, P.D.3
-
33
-
-
0031707469
-
Noninvasive prediction of fibrosis in C282Y homozygous hemochromatosis
-
Guyader D, Jacquelinet C, Moirand R, et al. Noninvasive prediction of fibrosis in C282Y homozygous hemochromatosis. Gastroenterology. 1998;115:929-936.
-
(1998)
Gastroenterology
, vol.115
, pp. 929-936
-
-
Guyader, D.1
Jacquelinet, C.2
Moirand, R.3
-
34
-
-
10744225120
-
Digenic inheritance of mutations in HAMP and HFE results in different types of haemochromatosis
-
Merryweather-Clarke AT, Cadet E, Bomford A, et al. Digenic inheritance of mutations in HAMP and HFE results in different types of haemochromatosis. Hum Mol Genet. 2003;12:2241-2247.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2241-2247
-
-
Merryweather-Clarke, A.T.1
Cadet, E.2
Bomford, A.3
-
35
-
-
9144252017
-
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
-
Papanikolaou G, Samuels ME, Ludwig EH, et al. Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nat Genet. 2004;36:77-82.
-
(2004)
Nat Genet
, vol.36
, pp. 77-82
-
-
Papanikolaou, G.1
Samuels, M.E.2
Ludwig, E.H.3
-
36
-
-
1642367900
-
HAMP as a modifier gene that increases the phenotypic expression of the HFE pC282Y homozygous genotype
-
Jacolot S, Le Gac G, Scotet V, Quere I, Mura C, Ferec C. HAMP as a modifier gene that increases the phenotypic expression of the HFE pC282Y homozygous genotype. Blood. 2004;103:2835-2840.
-
(2004)
Blood
, vol.103
, pp. 2835-2840
-
-
Jacolot, S.1
Le Gac, G.2
Scotet, V.3
Quere, I.4
Mura, C.5
Ferec, C.6
-
37
-
-
4544314123
-
The recently identified type 2A juvenile haemochromatosis gene (HJV), a second candidate modifier of the C282Y homozygous phenotype
-
Le Gac G, Scotet V, Ka C, et al. The recently identified type 2A juvenile haemochromatosis gene (HJV), a second candidate modifier of the C282Y homozygous phenotype. Hum Mol Genet. 2004;13:1913-1918.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 1913-1918
-
-
Le Gac, G.1
Scotet, V.2
Ka, C.3
-
39
-
-
25144486612
-
Prediction of progression to cirrhosis by a glutathione S-transferase P1 polymorphism in subjects with hereditary hemochromatosis
-
Stickel F, Oesterreicher CH, Datz C, et al. Prediction of progression to cirrhosis by a glutathione S-transferase P1 polymorphism in subjects with hereditary hemochromatosis. Arch Intern Med. 2005;165:1815-1817.
-
(2005)
Arch Intern Med
, vol.165
, pp. 1815-1817
-
-
Stickel, F.1
Oesterreicher, C.H.2
Datz, C.3
-
40
-
-
21344463609
-
TGF-beta1 codon 25 gene polymorphism is associated with cirrhosis in patients with hereditary hemochromatosis
-
Oesterreicher CH, Datz C, Stickel F, et al. TGF-beta1 codon 25 gene polymorphism is associated with cirrhosis in patients with hereditary hemochromatosis. Cytokine. 2005;31:142-148.
-
(2005)
Cytokine
, vol.31
, pp. 142-148
-
-
Oesterreicher, C.H.1
Datz, C.2
Stickel, F.3
|