HFE mutation and dietary iron content interact to increase ischemia/reperfusion injury of the heart in mice

Circulation Research

Volumn 92, Issue 11, 2003, Pages 1240-1246

  Turoczi, Tibor ^a   Jun, Li ^a   Cordis, Gerald ^a   Morris, James E ^b   Maulik, Nilanjana ^a   Stevens, Richard G ^a   Das, Dipak K ^a  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^b PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

Antioxidant enzymes; Hereditary hemochromatosis; Iron overload; Oxidative stress; Reactive oxygen species

Indexed keywords

CATALASE; ENZYME; GLUTATHIONE PEROXIDASE; HFE PROTEIN; IRON; MALONALDEHYDE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; ANTIOXIDANT; HFE PROTEIN, MOUSE; HLA ANTIGEN CLASS 1; MEMBRANE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; GENE MUTATION; GENETIC DISORDER; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART VENTRICLE FAILURE; HEMOCHROMATOSIS; INJURY SCALE; IRON INTAKE; IRON OVERLOAD; KNOCKOUT MOUSE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; REPERFUSION INJURY; ANIMAL; DIET; ENZYMOLOGY; GENETICS; HEART CONTRACTION; HEART MUSCLE; HEMODYNAMICS; METABOLISM; MOUSE MUTANT; MUTATION; ORAL DRUG ADMINISTRATION; PATHOLOGY; PATHOPHYSIOLOGY;

ADMINISTRATION, ORAL; ANIMALS; ANTIOXIDANTS; APOPTOSIS; DIET; HEMOCHROMATOSIS; HEMODYNAMIC PROCESSES; HISTOCOMPATIBILITY ANTIGENS CLASS I; IRON; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MUTATION; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; REACTIVE OXYGEN SPECIES;

EID: 0037704226     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000076890.59807.23     Document Type: Article

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