Hepatotoxicity of iron overload: Mechanisms of iron-induced hepatic fibrogenesis

Seminars in Liver Disease

Volumn 25, Issue 4, 2005, Pages 433-449

  Ramm, Grant A ^a,b   Ruddell, Richard G ^b  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Hemochromatosis; Hepatic fibrosis; Hepatic stellate cell; Hepatotoxicity; Iron

Indexed keywords

CARRIER PROTEIN; COLLAGEN; CYTOKINE; HEMOJUVELIN; HEPCIDIN; IRON; IRON BINDING PROTEIN; LIVER PROTEIN; OXYGEN RADICAL; TRANSFERRIN RECEPTOR; TRANSFERRIN RECEPTOR 2;

APOPTOSIS; BIOACCUMULATION; CELL ACTIVATION; CELL INTERACTION; CELL ORGANELLE; CELL TRANSFORMATION; DNA DAMAGE; EXTRACELLULAR MATRIX; FIBROGENESIS; HEMOCHROMATOSIS; HUMAN; IMMUNOHISTOCHEMISTRY; INTESTINE ABSORPTION; IRON ABSORPTION; IRON METABOLISM; IRON OVERLOAD; IRON STORAGE; IRON TRANSPORT; LIPID MEMBRANE; LIPID PEROXIDATION; LIVER CELL DAMAGE; LIVER CIRRHOSIS; LIVER FIBROSIS; LIVER LYSOSOME; LIVER METABOLISM; LIVER MITOCHONDRION; LIVER NECROSIS; LIVER PARENCHYMA; LIVER TOXICITY; MYOFIBROBLAST; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; STELLATE CELL;

ANIMALS; DISEASE PROGRESSION; HEPATOCYTES; HUMANS; IRON; IRON OVERLOAD; LIVER CIRRHOSIS; RISK FACTORS;

EID: 28444454447     PISSN: 02728087     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-923315     Document Type: Review

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