Iron-dependent activation of NF-κB in Kupffer cells: A priming mechanism for alcoholic liver disease

Alcohol

Volumn 30, Issue 2, 2003, Pages 107-113

  Xiong, Shigang ^a   She, Hongyun ^a   Sung, Chin K ^a   Tsukamoto, Hidekazu ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Alcoholic liver disease (ALD); Chelatable iron; Hepatic macrophages; I kappa B kinase (IKK); Nuclear factor kappa B (NF B)

Indexed keywords

CYTOKINE; DEFERIPRONE; FERROUS ION; I KAPPA B ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; IRON; IRON CHELATE; IRON COMPLEX; IRON REGULATORY FACTOR; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1; NITRIC OXIDE; NUCLEAR PROTEIN; PEROXYNITRITE; PROTEIN KINASE P60; TUMOR NECROSIS FACTOR ALPHA;

ALCOHOL LIVER CIRRHOSIS; ALCOHOL LIVER DISEASE; BIOACCUMULATION; BLOOD TRANSFUSION; CELL ACTIVITY; CELL CULTURE; CELL DAMAGE; CELL FUNCTION; CELL ISOLATION; CELLULAR DISTRIBUTION; CONFERENCE PAPER; DISEASE EXACERBATION; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HYPOTHESIS; IN VITRO STUDY; IRON ABSORPTION; IRON STORAGE; IRON THERAPY; KUPFFER CELL; LIPOPHILICITY; LIVER CELL; MACROPHAGE; MOLECULAR WEIGHT; MONOCYTE; NONHUMAN; OXIDATION REDUCTION REACTION; PATHOGENESIS; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; REDUCTION; SIGNAL TRANSDUCTION; TARGET CELL; THALASSEMIA; UPREGULATION;

EID: 0042384695     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-8329(03)00100-9     Document Type: Conference Paper

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