-
1
-
-
0028049495
-
Regulators of iron balance in humans
-
Finch C. Regulators of iron balance in humans. Blood 1994;84:1697-1702
-
(1994)
Blood
, vol.84
, pp. 1697-1702
-
-
Finch, C.1
-
2
-
-
0021474453
-
Role of the liver in normal iron metabolism
-
Bacon BR, Tavill AS. Role of the liver in normal iron metabolism. Semin Liver Dis 1984;4:181-192
-
(1984)
Semin Liver Dis
, vol.4
, pp. 181-192
-
-
Bacon, B.R.1
Tavill, A.S.2
-
3
-
-
0003117763
-
Iron storage disease
-
MacSween RNM, Anthony PP, Scheuer PJ, Burt AD, Portmann BC, eds. London, England: Churchill Livingstone
-
Searle J, Kerr JFR, Halliday JW, Powell LW. Iron storage disease In: MacSween RNM, Anthony PP, Scheuer PJ, Burt AD, Portmann BC, eds. Pathology of the Liver. 3rd ed. London, England: Churchill Livingstone; 1994:219-241
-
(1994)
Pathology of the Liver. 3rd Ed.
, pp. 219-241
-
-
Searle, J.1
Kerr, J.F.R.2
Halliday, J.W.3
Powell, L.W.4
-
4
-
-
0015239150
-
Effect of iron loading on non-heme iron compounds in different liver cell populations
-
Van Wyk CP, Linder-Horowitz M, Munro HN. Effect of iron loading on non-heme iron compounds in different liver cell populations. J Biol Chem 1971;246: 1025-1031
-
(1971)
J Biol Chem
, vol.246
, pp. 1025-1031
-
-
Van Wyk, C.P.1
Linder-Horowitz, M.2
Munro, H.N.3
-
5
-
-
0030608152
-
The ferritins: Molecular properties, iron storage function and cellular regulation
-
Harrison PM, Arosio P. The ferritins: molecular properties, iron storage function and cellular regulation. Biochim Biophys Acta 1996;1275:161-203
-
(1996)
Biochim Biophys Acta
, vol.1275
, pp. 161-203
-
-
Harrison, P.M.1
Arosio, P.2
-
7
-
-
0036400025
-
Ceruloplasmin metabolism and function
-
Hellman NE, Gitlin JD. Ceruloplasmin metabolism and function. Annu Rev Nutr 2002;22:439-458
-
(2002)
Annu Rev Nutr
, vol.22
, pp. 439-458
-
-
Hellman, N.E.1
Gitlin, J.D.2
-
8
-
-
0033693730
-
Haptoglobin: Function and polymorphism
-
Wassell J. Haptoglobin: function and polymorphism. Clin Lab 2000;46:547-552
-
(2000)
Clin Lab
, vol.46
, pp. 547-552
-
-
Wassell, J.1
-
9
-
-
0036259938
-
Hemopexin: Structure, function, and regulation
-
Tolosano E, Altruda F. Hemopexin: structure, function, and regulation. DNA Cell Biol 2002;21:297-306
-
(2002)
DNA Cell Biol
, vol.21
, pp. 297-306
-
-
Tolosano, E.1
Altruda, F.2
-
10
-
-
0037962795
-
The orchestration of body iron intake: How and where do enterocytes receive their cues?
-
Frazer DM, Anderson GJ. The orchestration of body iron intake: how and where do enterocytes receive their cues? Blood Cells Mol Dis 2003;30:288-297
-
(2003)
Blood Cells Mol Dis
, vol.30
, pp. 288-297
-
-
Frazer, D.M.1
Anderson, G.J.2
-
12
-
-
0032427653
-
Kupffer cell staining by an HFE-specific monoclonal antibody: Implications for hereditary haemochromatosis
-
Bastin JM, Jones M, O'Callaghan CA, Schimanski L, Mason DY, Townsend AR. Kupffer cell staining by an HFE-specific monoclonal antibody: implications for hereditary haemochromatosis. Br J Haematol 1998;103:931-941
-
(1998)
Br J Haematol
, vol.103
, pp. 931-941
-
-
Bastin, J.M.1
Jones, M.2
O'Callaghan, C.A.3
Schimanski, L.4
Mason, D.Y.5
Townsend, A.R.6
-
13
-
-
0842263988
-
Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes
-
Zhang AS, Xiong S, Tsukamoto H, Enns CA. Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes. Blood 2004;103:1509-1514
-
(2004)
Blood
, vol.103
, pp. 1509-1514
-
-
Zhang, A.S.1
Xiong, S.2
Tsukamoto, H.3
Enns, C.A.4
-
14
-
-
20044366342
-
Kupffer cells and macrophages are not required for hepatic hepcidin activation during iron overload
-
Montosi G, Corradini E, Garuti C, et al. Kupffer cells and macrophages are not required for hepatic hepcidin activation during iron overload. Hepatology 2005;41:545-552
-
(2005)
Hepatology
, vol.41
, pp. 545-552
-
-
Montosi, G.1
Corradini, E.2
Garuti, C.3
-
15
-
-
17844362181
-
Iron- and inflammation-induced hepcidin gene expression in mice is not mediated by Kupffer cells in vivo
-
Lou DQ, Lesbordes JC, Nicolas G, et al. Iron- and inflammation-induced hepcidin gene expression in mice is not mediated by Kupffer cells in vivo. Hepatology 2005;41:1056-1064
-
(2005)
Hepatology
, vol.41
, pp. 1056-1064
-
-
Lou, D.Q.1
Lesbordes, J.C.2
Nicolas, G.3
-
16
-
-
0028338934
-
Identification and characterization of a receptor for tissue ferritin on activated rat lipocytes
-
Ramm GA, Britton RS, O'Neill R, Bacon BR. Identification and characterization of a receptor for tissue ferritin on activated rat lipocytes. J Clin Invest 1994;94:9-15
-
(1994)
J Clin Invest
, vol.94
, pp. 9-15
-
-
Ramm, G.A.1
Britton, R.S.2
O'Neill, R.3
Bacon, B.R.4
-
17
-
-
28444496411
-
Regulation of liver iron metabolism
-
Templeton DM, ed. New York, NY: Marcel Dekker
-
Cairo G. Regulation of liver iron metabolism. In: Templeton DM, ed. Molecular and Cellular Iron Transport. New York, NY: Marcel Dekker; 2001:613-641
-
(2001)
Molecular and Cellular Iron Transport
, pp. 613-641
-
-
Cairo, G.1
-
18
-
-
0031833094
-
Regulation of transferrin function and expression: Review and update
-
Lok CN, Loh TT. Regulation of transferrin function and expression: review and update. Biol Signals Recept 1998;7: 157-178
-
(1998)
Biol Signals Recept
, vol.7
, pp. 157-178
-
-
Lok, C.N.1
Loh, T.T.2
-
19
-
-
0000960483
-
Uptake of transferrin-bound iron by mammalian cells
-
Templeton DM, ed. New York, NY: Marcel Dekker
-
Trinder D, Morgan E. Uptake of transferrin-bound iron by mammalian cells. In: Templeton DM, ed. Molecular and Cellular Iron Transport. New York, NY: Marcel Dekker; 2001:427-449
-
(2001)
Molecular and Cellular Iron Transport
, pp. 427-449
-
-
Trinder, D.1
Morgan, E.2
-
20
-
-
21244468617
-
Transport of non-transferrin-bound iron by hepatocytes
-
Templeton DM, ed. New York, NY: Marcel Dekker
-
Parkes JG, Templeton DM. Transport of non-transferrin-bound iron by hepatocytes. In: Templeton DM, ed. Molecular and Cellular Iron Transport. New York, NY: Marcel Dekker; 2001:451-466
-
(2001)
Molecular and Cellular Iron Transport
, pp. 451-466
-
-
Parkes, J.G.1
Templeton, D.M.2
-
21
-
-
0023753632
-
The effects of an antibody to the rat transferrin receptor and of rat serum albumin on the uptake of diferric transferrin by rat hepatocytes
-
Trinder D, Morgan EH, Baker E. The effects of an antibody to the rat transferrin receptor and of rat serum albumin on the uptake of diferric transferrin by rat hepatocytes. Biochim Biophys Acta 1988;943:440-446
-
(1988)
Biochim Biophys Acta
, vol.943
, pp. 440-446
-
-
Trinder, D.1
Morgan, E.H.2
Baker, E.3
-
22
-
-
0025766932
-
Uptake and endocytic pathway of transferrin and iron in perfused rat liver
-
Goldenberg H, Seelos C, Chatwani S, Chegini S, Pumm R. Uptake and endocytic pathway of transferrin and iron in perfused rat liver. Biochim Biophys Acta 1991;1067:145-152
-
(1991)
Biochim Biophys Acta
, vol.1067
, pp. 145-152
-
-
Goldenberg, H.1
Seelos, C.2
Chatwani, S.3
Chegini, S.4
Pumm, R.5
-
23
-
-
0025972105
-
Specificity of hepatic iron uptake from plasma transferrin in the rat
-
Morgan EH. Specificity of hepatic iron uptake from plasma transferrin in the rat. Comp Biochem Physiol A 1991;99:91-95
-
(1991)
Comp Biochem Physiol A
, vol.99
, pp. 91-95
-
-
Morgan, E.H.1
-
25
-
-
0024579708
-
Regulation of the hepatic transferrin receptor in hereditary hemochromatosis
-
Lombard M, Bomford A, Hynes M, et al. Regulation of the hepatic transferrin receptor in hereditary hemochromatosis. Hepatology 1989;9:1-5
-
(1989)
Hepatology
, vol.9
, pp. 1-5
-
-
Lombard, M.1
Bomford, A.2
Hynes, M.3
-
26
-
-
0025151812
-
Effect of cellular iron concentration on iron uptake by hepatocytes
-
Trinder D, Batey RG, Morgan EH, Baker E. Effect of cellular iron concentration on iron uptake by hepatocytes. Am J Physiol 1990;259:G611-G617
-
(1990)
Am J Physiol
, vol.259
-
-
Trinder, D.1
Batey, R.G.2
Morgan, E.H.3
Baker, E.4
-
27
-
-
0024410452
-
Uptake and distribution of transferrin and iron in perfused, iron-deficient rat liver
-
Holmes JM, Morgan EH. Uptake and distribution of transferrin and iron in perfused, iron-deficient rat liver. Am J Physiol 1989;256:G1022-G1027
-
(1989)
Am J Physiol
, vol.256
-
-
Holmes, J.M.1
Morgan, E.H.2
-
28
-
-
4143051431
-
Transferrin receptor 1
-
Aisen P. Transferrin receptor 1. Int J Biochem Cell Biol 2004;36:2137-2143
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2137-2143
-
-
Aisen, P.1
-
29
-
-
4243153440
-
The transferrin receptor
-
Templeton DM, ed. New York, NY: Marcel Dekker
-
Enns CA. The transferrin receptor. In: Templeton DM, ed. Molecular and Cellular Iron Transport. New York, NY: Marcel Dekker; 2001:71-94
-
(2001)
Molecular and Cellular Iron Transport
, pp. 71-94
-
-
Enns, C.A.1
-
30
-
-
0026773665
-
Kinetic characterization of reductant dependent processes in iron mobilization from endocytic vesicles
-
Watkins JA, Altazan JD, Elder P, et al. Kinetic characterization of reductant dependent processes in iron mobilization from endocytic vesicles. Biochemistry 1992;31:5820-5830
-
(1992)
Biochemistry
, vol.31
, pp. 5820-5830
-
-
Watkins, J.A.1
Altazan, J.D.2
Elder, P.3
-
31
-
-
0025924788
-
A new role for the transferrin receptor in the release of iron from transferrin
-
Bali PK, Zak O, Aisen P. A new role for the transferrin receptor in the release of iron from transferrin. Biochemistry 1991;30:324-328
-
(1991)
Biochemistry
, vol.30
, pp. 324-328
-
-
Bali, P.K.1
Zak, O.2
Aisen, P.3
-
32
-
-
0036196205
-
Mechanisms of iron accumulation in hereditary hemochromatosis
-
Fleming RE, Sly WS. Mechanisms of iron accumulation in hereditary hemochromatosis. Annu Rev Physiol 2002;64:663-680
-
(2002)
Annu Rev Physiol
, vol.64
, pp. 663-680
-
-
Fleming, R.E.1
Sly, W.S.2
-
33
-
-
0032477866
-
NRAMP2 is mutated in the anemic Belgrade (b) rat: Evidence of a role for Nramp2 in endosomal iron transport
-
Fleming MD, Romano MA, Su MA, Garrick LM, Garrick MD, Andrews NC. NRAMP2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. Proc Natl Acad Sci USA 1998;95:1148-1153
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 1148-1153
-
-
Fleming, M.D.1
Romano, M.A.2
Su, M.A.3
Garrick, L.M.4
Garrick, M.D.5
Andrews, N.C.6
-
34
-
-
0022457270
-
Uptake and subcellular processing of 59Fe-125I-labelled transferrin by rat liver
-
Morgan EH, Smith GD, Peters TJ. Uptake and subcellular processing of 59Fe-125I-labelled transferrin by rat liver. Biochem J 1986;237:163-173
-
(1986)
Biochem J
, vol.237
, pp. 163-173
-
-
Morgan, E.H.1
Smith, G.D.2
Peters, T.J.3
-
35
-
-
0022448747
-
Subcellular localization of transferrin protein and iron in the perfused rat liver. Effect of Triton WR 1339, digitonin and temperature
-
Sibille J-C, Octave J-N, Schneider Y-J, Truet A, Crichton RR. Subcellular localization of transferrin protein and iron in the perfused rat liver. Effect of Triton WR 1339, digitonin and temperature. Eur J Biochem 1986;155:47-55
-
(1986)
Eur J Biochem
, vol.155
, pp. 47-55
-
-
Sibille, J.-C.1
Octave, J.-N.2
Schneider, Y.-J.3
Truet, A.4
Crichton, R.R.5
-
36
-
-
0023131423
-
Heterogeneous distribution of transferrin receptors on parenchymal and nonparenchymal liver cells: Biochemical and morphological evidence
-
Vogel W, Bomford A, Young S, Williams R. Heterogeneous distribution of transferrin receptors on parenchymal and nonparenchymal liver cells: biochemical and morphological evidence. Blood 1987;69:264-270
-
(1987)
Blood
, vol.69
, pp. 264-270
-
-
Vogel, W.1
Bomford, A.2
Young, S.3
Williams, R.4
-
37
-
-
0020597630
-
Transferrin receptors in human tissues: Their distribution and possible clinical relevance
-
Gatter KC, Brown G, Trowbridge IS, Woolston RE, Mason DY. Transferrin receptors in human tissues: their distribution and possible clinical relevance. J Clin Pathol 1983;36:539-545
-
(1983)
J Clin Pathol
, vol.36
, pp. 539-545
-
-
Gatter, K.C.1
Brown, G.2
Trowbridge, I.S.3
Woolston, R.E.4
Mason, D.Y.5
-
38
-
-
0023943266
-
Immunoelectron microscopic localization of hepatic transferrin receptors in human liver with and without iron overload
-
De Vos R, Sciot R, van Eyken P, Desmet VJ. Immunoelectron microscopic localization of hepatic transferrin receptors in human liver with and without iron overload. Virchows Arch B Cell Pathol Incl Mol Pathol 1988;55:11-17
-
(1988)
Virchows Arch B Cell Pathol Incl Mol Pathol
, vol.55
, pp. 11-17
-
-
De Vos, R.1
Sciot, R.2
Van Eyken, P.3
Desmet, V.J.4
-
39
-
-
0031784423
-
Cellular expression and regulation of iron transport and storage proteins in genetic haemochromatosis
-
Basclain KA, Shiklin KB, Withers G, Reed WD, Jeffrey GP. Cellular expression and regulation of iron transport and storage proteins in genetic haemochromatosis. J Gastroenterol Hepatol 1998;13:624-634
-
(1998)
J Gastroenterol Hepatol
, vol.13
, pp. 624-634
-
-
Basclain, K.A.1
Shiklin, K.B.2
Withers, G.3
Reed, W.D.4
Jeffrey, G.P.5
-
40
-
-
0022481514
-
Liver endothelium mediates the uptake of iron-transferrin complex by hepatocytes
-
Tavassoli M, Kishimoto T, Soda R, Kataoka M, Harjes K. Liver endothelium mediates the uptake of iron-transferrin complex by hepatocytes. Exp Cell Res 1986;165:369-379
-
(1986)
Exp Cell Res
, vol.165
, pp. 369-379
-
-
Tavassoli, M.1
Kishimoto, T.2
Soda, R.3
Kataoka, M.4
Harjes, K.5
-
41
-
-
0037406902
-
Identification and characterization of the hepatic stellate cell transferrin receptor
-
Bridle KR, Crawford DHG, Ramm GA. Identification and characterization of the hepatic stellate cell transferrin receptor. Am J Pathol 2003;162:1661-1667
-
(2003)
Am J Pathol
, vol.162
, pp. 1661-1667
-
-
Bridle, K.R.1
Crawford, D.H.G.2
Ramm, G.A.3
-
42
-
-
0025360805
-
Immunolocalization of transferrin and transferrin receptor in mouse small intestinal absorptive cells
-
Levine DS, Woods JW. Immunolocalization of transferrin and transferrin receptor in mouse small intestinal absorptive cells. J Histochem Cytochem 1990;38:851-858
-
(1990)
J Histochem Cytochem
, vol.38
, pp. 851-858
-
-
Levine, D.S.1
Woods, J.W.2
-
43
-
-
0024437898
-
Change in transferrin receptor distribution in regenerating rat liver
-
Hirose-Kumagai A, Akamatsu N. Change in transferrin receptor distribution in regenerating rat liver. Biochem Biophys Res Commun 1989;164:1105-1112
-
(1989)
Biochem Biophys Res Commun
, vol.164
, pp. 1105-1112
-
-
Hirose-Kumagai, A.1
Akamatsu, N.2
-
44
-
-
0033826764
-
Iron regulatory proteins and the molecular control of mammalian iron metabolism
-
Eisenstein RS. Iron regulatory proteins and the molecular control of mammalian iron metabolism. Annu Rev Nutr 2000;20:627-662
-
(2000)
Annu Rev Nutr
, vol.20
, pp. 627-662
-
-
Eisenstein, R.S.1
-
45
-
-
0024953316
-
Transferrin receptor expression in normal, iron-deficient and iron-overloaded rats
-
Lu JP, Hayashi K, Awai M. Transferrin receptor expression in normal, iron-deficient and iron-overloaded rats. Acta Pathol Jpn 1989;39:759-764
-
(1989)
Acta Pathol Jpn
, vol.39
, pp. 759-764
-
-
Lu, J.P.1
Hayashi, K.2
Awai, M.3
-
46
-
-
0025303916
-
Transferrin receptor expression in rat liver: Immunohistochemical and biochemical analysis of the effect of age and iron storage
-
Sciot R, Verhoeven G, Van Eyken P, Cailleau J, Desmet VJ. Transferrin receptor expression in rat liver: immunohistochemical and biochemical analysis of the effect of age and iron storage. Hepatology 1990;11:416-427
-
(1990)
Hepatology
, vol.11
, pp. 416-427
-
-
Sciot, R.1
Verhoeven, G.2
Van Eyken, P.3
Cailleau, J.4
Desmet, V.J.5
-
47
-
-
0026321461
-
Regulation of hepatic transferrin, transferrin receptor and ferritin genes in human siderosis
-
Pietrangelo A, Rocchi E, Ferrari A, Ventura E, Cairo G. Regulation of hepatic transferrin, transferrin receptor and ferritin genes in human siderosis. Hepatology 1991;14:1083-1089
-
(1991)
Hepatology
, vol.14
, pp. 1083-1089
-
-
Pietrangelo, A.1
Rocchi, E.2
Ferrari, A.3
Ventura, E.4
Cairo, G.5
-
48
-
-
0022515085
-
The mechanisms of iron uptake by fetal rat hepatocytes in culture
-
Trinder D, Morgan EH, Baker E. The mechanisms of iron uptake by fetal rat hepatocytes in culture. Hepatology 1986;6:852-858
-
(1986)
Hepatology
, vol.6
, pp. 852-858
-
-
Trinder, D.1
Morgan, E.H.2
Baker, E.3
-
49
-
-
0021235870
-
Increase of transferrin receptors in regenerating rat liver cells after partial hepatectomy
-
Tei I, Makino Y, Kadoofuku T, Kanamura I, Konn K. Increase of transferrin receptors in regenerating rat liver cells after partial hepatectomy. Biochem Biophys Res Commun 1984;121:717-721
-
(1984)
Biochem Biophys Res Commun
, vol.121
, pp. 717-721
-
-
Tei, I.1
Makino, Y.2
Kadoofuku, T.3
Kanamura, I.4
Konn, K.5
-
50
-
-
0029953577
-
Transferrin receptor-independent uptake of differic transferrin by human hepatoma cells with antisense inhibition of receptor expression
-
Trinder D, Zak O, Aisen P. Transferrin receptor-independent uptake of differic transferrin by human hepatoma cells with antisense inhibition of receptor expression. Hepatology 1996;23:1512-1520
-
(1996)
Hepatology
, vol.23
, pp. 1512-1520
-
-
Trinder, D.1
Zak, O.2
Aisen, P.3
-
51
-
-
0033597780
-
Molecular cloning of transferrin receptor 2: A new member of the transferrin receptor-like family
-
Kawabata H, Yang R, Hirama T, et al. Molecular cloning of transferrin receptor 2: a new member of the transferrin receptor-like family. J Biol Chem 1999;274:20826-20832
-
(1999)
J Biol Chem
, vol.274
, pp. 20826-20832
-
-
Kawabata, H.1
Yang, R.2
Hirama, T.3
-
52
-
-
0141866926
-
Effects of cell proliferation on the uptake of transferrin-bound iron by human hepatoma cells
-
Lee AW, Oates PS, Trinder D. Effects of cell proliferation on the uptake of transferrin-bound iron by human hepatoma cells. Hepatology 2003;38:967-977
-
(2003)
Hepatology
, vol.38
, pp. 967-977
-
-
Lee, A.W.1
Oates, P.S.2
Trinder, D.3
-
53
-
-
8644221378
-
Transferrin receptor 2 mediates a biphasic pattern of transferrin uptake associated with ligand delivery to multivesicular bodies
-
Robb AD, Ericsson M, Wessling-Resnick M. Transferrin receptor 2 mediates a biphasic pattern of transferrin uptake associated with ligand delivery to multivesicular bodies. Am J Physiol Cell Physiol 2004;287:C1769-C1775
-
(2004)
Am J Physiol Cell Physiol
, vol.287
-
-
Robb, A.D.1
Ericsson, M.2
Wessling-Resnick, M.3
-
54
-
-
0034007995
-
Transferrin receptor 2: Continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis
-
Fleming RE, Migas MC, Holden CC, et al. Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis. Proc Natl Acad Sci USA 2000;97:2214-2219
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 2214-2219
-
-
Fleming, R.E.1
Migas, M.C.2
Holden, C.C.3
-
55
-
-
0037111572
-
Structural, functional, and tissue distribution analysis of human transferrin receptor-2 by murine monoclonal antibodies and polyclonal antiserum
-
Deaglio S, Capobianco A, Cali A, et al. Structural, functional, and tissue distribution analysis of human transferrin receptor-2 by murine monoclonal antibodies and polyclonal antiserum. Blood 2002;100:3782-3789
-
(2002)
Blood
, vol.100
, pp. 3782-3789
-
-
Deaglio, S.1
Capobianco, A.2
Cali, A.3
-
56
-
-
10244255021
-
Regulation of transferrin receptor 2 protein levels by transferrin
-
Robb A, Wessling-Resnick M. Regulation of transferrin receptor 2 protein levels by transferrin. Blood 2004;104:4294-4299
-
(2004)
Blood
, vol.104
, pp. 4294-4299
-
-
Robb, A.1
Wessling-Resnick, M.2
-
57
-
-
10244265904
-
Diferric transferrin regulates transferrin receptor 2 protein stability
-
Johnson MB, Enns CA. Diferric transferrin regulates transferrin receptor 2 protein stability. Blood 2004;104:4287-4293
-
(2004)
Blood
, vol.104
, pp. 4287-4293
-
-
Johnson, M.B.1
Enns, C.A.2
-
58
-
-
0034022636
-
The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22
-
Camaschella C, Roetto A, Cali A, et al. The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22. Nat Genet 2000;25:14-15
-
(2000)
Nat Genet
, vol.25
, pp. 14-15
-
-
Camaschella, C.1
Roetto, A.2
Cali, A.3
-
59
-
-
0036678091
-
Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis
-
Fleming RE, Ahmann JR, Migas MC, et al. Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis. Proc Natl Acad Sci USA 2002;99: 10653-10658
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10653-10658
-
-
Fleming, R.E.1
Ahmann, J.R.2
Migas, M.C.3
-
60
-
-
0025094141
-
The role of transferrin in the mechanism of cellular iron uptake
-
Thorstensen K, Romslo I. The role of transferrin in the mechanism of cellular iron uptake. Biochem J 1990;271: 1-10
-
(1990)
Biochem J
, vol.271
, pp. 1-10
-
-
Thorstensen, K.1
Romslo, I.2
-
61
-
-
0020679806
-
Transferrin binding and iron uptake in mouse hepatocytes
-
Cole ES, Glass J. Transferrin binding and iron uptake in mouse hepatocytes. Biochim Biophys Acta 1983;762:102-110
-
(1983)
Biochim Biophys Acta
, vol.762
, pp. 102-110
-
-
Cole, E.S.1
Glass, J.2
-
62
-
-
0023949731
-
Uptake of iron from transferrin by isolated rat hepatocytes. A redox-mediated plasma membrane process?
-
Thorstensen K, Romslo I. Uptake of iron from transferrin by isolated rat hepatocytes. A redox-mediated plasma membrane process? J Biol Chem 1988;263:8844-8850
-
(1988)
J Biol Chem
, vol.263
, pp. 8844-8850
-
-
Thorstensen, K.1
Romslo, I.2
-
63
-
-
0030761075
-
Inhibition of uptake of transferrin-bound iron by human hepatoma cells by nontransferrin-bound iron
-
Trinder D, Morgan E. Inhibition of uptake of transferrin-bound iron by human hepatoma cells by nontransferrin-bound iron. Hepatology 1997;26:691-698
-
(1997)
Hepatology
, vol.26
, pp. 691-698
-
-
Trinder, D.1
Morgan, E.2
-
64
-
-
0032053475
-
Ferric citrate uptake by cultured rat hepatocytes is inhibited in the presence of transferrin
-
Graham RM, Morgan EH, Baker E. Ferric citrate uptake by cultured rat hepatocytes is inhibited in the presence of transferrin. Eur J Biochem 1998;253:139-145
-
(1998)
Eur J Biochem
, vol.253
, pp. 139-145
-
-
Graham, R.M.1
Morgan, E.H.2
Baker, E.3
-
65
-
-
0030755366
-
Cloning and characterization of a mammalian proton-coupled metal-ion transporter
-
Gunshin H, Mackenzie B, Berger UV, et al. Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 1997;388:482-488
-
(1997)
Nature
, vol.388
, pp. 482-488
-
-
Gunshin, H.1
Mackenzie, B.2
Berger, U.V.3
-
66
-
-
0023219279
-
Anemia of the Belgrade rat: Evidence for defective membrane transport of iron
-
Bowen BJ, Morgan EH. Anemia of the Belgrade rat: evidence for defective membrane transport of iron. Blood 1987;70:38-44
-
(1987)
Blood
, vol.70
, pp. 38-44
-
-
Bowen, B.J.1
Morgan, E.H.2
-
67
-
-
0034786537
-
Cloning and gastrointestinal expression of hephaestin: Relationship to other iron transport proteins
-
Frazer DM, Vulpe CD, McKie AT, et al. Cloning and gastrointestinal expression of hephaestin: relationship to other iron transport proteins. Am J Physiol 2001;281:G931-G939
-
(2001)
Am J Physiol
, vol.281
-
-
Frazer, D.M.1
Vulpe, C.D.2
McKie, A.T.3
-
68
-
-
0034070941
-
Localisation of divalent metal transporter 1 (DMT1) to the microvillus membrane of rat duodenal enterocytes in iron deficiency, but to hepatocytes in iron overload
-
Trinder D, Oates PS, Thomas C, Sadlier J, Morgan EH. Localisation of divalent metal transporter 1 (DMT1) to the microvillus membrane of rat duodenal enterocytes in iron deficiency, but to hepatocytes in iron overload. Gut 2000;46:270-276
-
(2000)
Gut
, vol.46
, pp. 270-276
-
-
Trinder, D.1
Oates, P.S.2
Thomas, C.3
Sadlier, J.4
Morgan, E.H.5
-
69
-
-
0036566143
-
Expression of the two mRNA isoforms of the iron transporter Nramp2/DMT1 in mice and function of the iron responsive element
-
Tchernitchko D, Bourgeois M, Martin ME, Beaumont C. Expression of the two mRNA isoforms of the iron transporter Nramp2/DMT1 in mice and function of the iron responsive element. Biochem J 2002;363:449-455
-
(2002)
Biochem J
, vol.363
, pp. 449-455
-
-
Tchernitchko, D.1
Bourgeois, M.2
Martin, M.E.3
Beaumont, C.4
-
70
-
-
0038392370
-
Influence of parenteral iron preparations on non-transferrin bound iron uptake, the iron regulatory protein and the expression of ferritin and the divalent metal transporter DMT-1 in HepG2 human hepatoma cells
-
Scheiber-Mojdehkar B, Sturm B, Plank L, Kryzer I, Goldenberg H. Influence of parenteral iron preparations on non-transferrin bound iron uptake, the iron regulatory protein and the expression of ferritin and the divalent metal transporter DMT-1 in HepG2 human hepatoma cells. Biochem Pharmacol 2003;65:1973-1978
-
(2003)
Biochem Pharmacol
, vol.65
, pp. 1973-1978
-
-
Scheiber-Mojdehkar, B.1
Sturm, B.2
Plank, L.3
Kryzer, I.4
Goldenberg, H.5
-
71
-
-
17944388628
-
Nature of nontransferrin-bound iron
-
Hider RC. Nature of nontransferrin-bound iron. Eur J Clin Invest 2002;32(suppl 1):50-54
-
(2002)
Eur J Clin Invest
, vol.32
, Issue.SUPPL. 1
, pp. 50-54
-
-
Hider, R.C.1
-
72
-
-
0027360042
-
Studies on familial hypotransferrinemia: Unique clinical course and molecular pathology
-
Hayashi A, Wada Y, Suzuki T, Shimizu A. Studies on familial hypotransferrinemia: unique clinical course and molecular pathology. Am J Hum Genet 1993;53:201-213
-
(1993)
Am J Hum Genet
, vol.53
, pp. 201-213
-
-
Hayashi, A.1
Wada, Y.2
Suzuki, T.3
Shimizu, A.4
-
73
-
-
0023522698
-
Hereditary hypotransferrinemia with hemosiderosis, a murine disorder resembling human atransferrinemia
-
Bernstein SE. Hereditary hypotransferrinemia with hemosiderosis, a murine disorder resembling human atransferrinemia. J Lab Clin Med 1987;110:690-705
-
(1987)
J Lab Clin Med
, vol.110
, pp. 690-705
-
-
Bernstein, S.E.1
-
74
-
-
0011938460
-
Tissue distribution and clearance kinetics of non-transferrin-bound iron in the hypotransferrinemic mouse: A rodent model for hemochromatosis
-
Craven CM, Alexander J, Eldridge M, Kushner JP, Bernstein S, Kaplan J. Tissue distribution and clearance kinetics of non-transferrin-bound iron in the hypotransferrinemic mouse: a rodent model for hemochromatosis. Proc Natl Acad Sci USA 1987;84:3457-3461
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 3457-3461
-
-
Craven, C.M.1
Alexander, J.2
Eldridge, M.3
Kushner, J.P.4
Bernstein, S.5
Kaplan, J.6
-
75
-
-
0023007268
-
Characterization of non-transferrin-bound iron clearance by rat liver
-
Wright TL, Brissot P, Ma W-L, Weisinger RA. Characterization of non-transferrin-bound iron clearance by rat liver. J Biol Chem 1986;261:10909-10914
-
(1986)
J Biol Chem
, vol.261
, pp. 10909-10914
-
-
Wright, T.L.1
Brissot, P.2
Ma, W.-L.3
Weisinger, R.A.4
-
76
-
-
0028244452
-
Uptake of non-transferrin-bound iron by both reductive and nonreductive processes is modulated by intracellular iron
-
Randell EW, Parkes JG, Olivieri NF, Templeton DM. Uptake of non-transferrin-bound iron by both reductive and nonreductive processes is modulated by intracellular iron. J Biol Chem 1994;269:16046-16053
-
(1994)
J Biol Chem
, vol.269
, pp. 16046-16053
-
-
Randell, E.W.1
Parkes, J.G.2
Olivieri, N.F.3
Templeton, D.M.4
-
77
-
-
0032510294
-
Characterisation of non-transferrin-bound iron (ferric citrate) uptake by rat hepatoytes in culture
-
Baker E, Baker SM, Morgan EH. Characterisation of non-transferrin-bound iron (ferric citrate) uptake by rat hepatoytes in culture. Biochim Biophys Acta 1998;1380:21-30
-
(1998)
Biochim Biophys Acta
, vol.1380
, pp. 21-30
-
-
Baker, E.1
Baker, S.M.2
Morgan, E.H.3
-
78
-
-
0030697289
-
Functional expression cloning and characterization of SFT, a stimulator of Fe transport
-
Gutierrez JA, Yu J, Rivera S, Wessling-Resnick M. Functional expression cloning and characterization of SFT, a stimulator of Fe transport. J Cell Biol 1997;139:895-905
-
(1997)
J Cell Biol
, vol.139
, pp. 895-905
-
-
Gutierrez, J.A.1
Yu, J.2
Rivera, S.3
Wessling-Resnick, M.4
-
79
-
-
4444226451
-
Nontransferrin-bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosis
-
Chua AC, Olynyk JK, Leedman PJ, Trinder D. Nontransferrin-bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosis. Blood 2004;104:1519-1525
-
(2004)
Blood
, vol.104
, pp. 1519-1525
-
-
Chua, A.C.1
Olynyk, J.K.2
Leedman, P.J.3
Trinder, D.4
-
80
-
-
0032567459
-
Expression of SFT (stimulator of Fe transport) is enhanced by iron chelation in HeLa cells and by hemochromatosis in liver
-
Yu J, Yu ZK, Wessling-Resnick M. Expression of SFT (stimulator of Fe transport) is enhanced by iron chelation in HeLa cells and by hemochromatosis in liver. J Biol Chem 1998;273:34675-34678
-
(1998)
J Biol Chem
, vol.273
, pp. 34675-34678
-
-
Yu, J.1
Yu, Z.K.2
Wessling-Resnick, M.3
-
81
-
-
4544246612
-
CD163: A regulated hemoglobin scavenger receptor with a role in the anti-inflammatory response
-
Moestrup SK, Moller HJ. CD163: a regulated hemoglobin scavenger receptor with a role in the anti-inflammatory response. Ann Med 2004;36:347-354
-
(2004)
Ann Med
, vol.36
, pp. 347-354
-
-
Moestrup, S.K.1
Moller, H.J.2
-
82
-
-
0035843134
-
Identification of the haemoglobin scavenger receptor
-
Kristiansen M, Graversen JH, Jacobsen C, et al. Identification of the haemoglobin scavenger receptor. Nature 2001;409:198-201
-
(2001)
Nature
, vol.409
, pp. 198-201
-
-
Kristiansen, M.1
Graversen, J.H.2
Jacobsen, C.3
-
84
-
-
0032530341
-
Increased susceptibility in Hp knockout mice during acute hemolysis
-
Lim SK, Kim H, Lim SK, et al. Increased susceptibility in Hp knockout mice during acute hemolysis. Blood 1998;92: 1870-1877
-
(1998)
Blood
, vol.92
, pp. 1870-1877
-
-
Lim, S.K.1
Kim, H.2
Lim, S.K.3
-
85
-
-
0025764614
-
The murine haemopexin receptor. Evidence that the haemopexin-binding site resides on a 20 kDa subunit and that receptor recycling is regulated by protein kinase C
-
Smith A, Farooqui SM, Morgan WT. The murine haemopexin receptor. Evidence that the haemopexin-binding site resides on a 20 kDa subunit and that receptor recycling is regulated by protein kinase C. Biochem J 1991;276:417-425
-
(1991)
Biochem J
, vol.276
, pp. 417-425
-
-
Smith, A.1
Farooqui, S.M.2
Morgan, W.T.3
-
86
-
-
27144551314
-
Identification of the receptor scavenging hemopexin-heme complexes
-
Hvidberg V, Maniecki MB, Jacobsen C, Hojrup P, Moller HJ, Moestrup SK. Identification of the receptor scavenging hemopexin-heme complexes. Blood 2005;106:2572-2579
-
(2005)
Blood
, vol.106
, pp. 2572-2579
-
-
Hvidberg, V.1
Maniecki, M.B.2
Jacobsen, C.3
Hojrup, P.4
Moller, H.J.5
Moestrup, S.K.6
-
87
-
-
0034836428
-
LRP: A multifunctional scavenger and signaling receptor
-
Herz J, Strickland DK. LRP: a multifunctional scavenger and signaling receptor. J Clin Invest 2001;108:779-784
-
(2001)
J Clin Invest
, vol.108
, pp. 779-784
-
-
Herz, J.1
Strickland, D.K.2
-
88
-
-
0033485566
-
Defective recovery and severe renal damage after acute hemolysis in hemopexin-deficient mice
-
Tolosano E, Hirsch E, Patrucco E, et al. Defective recovery and severe renal damage after acute hemolysis in hemopexin-deficient mice. Blood 1999;94:3906-3914
-
(1999)
Blood
, vol.94
, pp. 3906-3914
-
-
Tolosano, E.1
Hirsch, E.2
Patrucco, E.3
-
89
-
-
0003240658
-
Cellular iron processing and storage: The role of ferritin
-
Brock JH, Halliday JW, Pippard MJ, Powell LW, eds. London, England: WB Saunders
-
Halliday JW, Ramm GA, Powell LW. Cellular iron processing and storage: the role of ferritin. In: Brock JH, Halliday JW, Pippard MJ, Powell LW, eds. Iron Metabolism in Health and Disease. London, England: WB Saunders; 1994:97-121
-
(1994)
Iron Metabolism in Health and Disease
, pp. 97-121
-
-
Halliday, J.W.1
Ramm, G.A.2
Powell, L.W.3
-
90
-
-
0019799496
-
Regulation of plasma ferritin by the isolated perfused rat liver
-
Mack U, Cooksley WG, Ferris RA, Powell LW, Halliday JW. Regulation of plasma ferritin by the isolated perfused rat liver. Br J Haematol 1981;47:403-412
-
(1981)
Br J Haematol
, vol.47
, pp. 403-412
-
-
Mack, U.1
Cooksley, W.G.2
Ferris, R.A.3
Powell, L.W.4
Halliday, J.W.5
-
91
-
-
0026705752
-
Functional roles of the ferritin receptors of human liver, hepatoma, lymphoid and erythroid cells
-
Moss D, Fargion S, Fracanzani AL, et al. Functional roles of the ferritin receptors of human liver, hepatoma, lymphoid and erythroid cells. J Inorg Biochem 1992;47:219-227
-
(1992)
J Inorg Biochem
, vol.47
, pp. 219-227
-
-
Moss, D.1
Fargion, S.2
Fracanzani, A.L.3
-
92
-
-
0027957998
-
Pathways of intracellular trafficking and release of ferritin by the liver in vivo: The effect of chloroquine and cytochalasin D
-
Ramm GA, Powell LW, Halliday JW. Pathways of intracellular trafficking and release of ferritin by the liver in vivo: the effect of chloroquine and cytochalasin D. Hepatology 1994;19:504-513
-
(1994)
Hepatology
, vol.19
, pp. 504-513
-
-
Ramm, G.A.1
Powell, L.W.2
Halliday, J.W.3
-
93
-
-
0023912979
-
Interaction between isolated hepatocytes and Kupffer cells in iron metabolism: A possible role for ferritin as an iron carrier protein
-
Sibille JC, Kondo H, Aisen P. Interaction between isolated hepatocytes and Kupffer cells in iron metabolism: a possible role for ferritin as an iron carrier protein. Hepatology 1998;8:296-301
-
(1998)
Hepatology
, vol.8
, pp. 296-301
-
-
Sibille, J.C.1
Kondo, H.2
Aisen, P.3
-
94
-
-
0344154421
-
Labile iron pool: The main determinant of cellular response to oxidative stress
-
Kruszewski M. Labile iron pool: the main determinant of cellular response to oxidative stress. Mutat Res 2003;531:81-92
-
(2003)
Mutat Res
, vol.531
, pp. 81-92
-
-
Kruszewski, M.1
-
95
-
-
19444375830
-
Ferritins: Structural and functional aspects
-
Templeton DM, ed. New York, NY: Marcel Dekker
-
Arosio P, Levi S. Ferritins: structural and functional aspects. In: Templeton DM, ed. Molecular and Cellular Iron Transport. New York, NY: Marcel Dekker; 2001:125-154
-
(2001)
Molecular and Cellular Iron Transport
, pp. 125-154
-
-
Arosio, P.1
Levi, S.2
-
96
-
-
0025267143
-
Biological and ultrastructural aspects of iron overload: An overview
-
Iancu TC. Biological and ultrastructural aspects of iron overload: an overview. Pediatr Pathol 1990;10:281-296
-
(1990)
Pediatr Pathol
, vol.10
, pp. 281-296
-
-
Iancu, T.C.1
-
97
-
-
0030846248
-
Ultrastructural sequences during liver iron overload in genetic hemochromatosis
-
Iancu TC, Deugnier Y, Halliday JW, Powell LW, Brissot P. Ultrastructural sequences during liver iron overload in genetic hemochromatosis. J Hepatol 1997;27:628-638
-
(1997)
J Hepatol
, vol.27
, pp. 628-638
-
-
Iancu, T.C.1
Deugnier, Y.2
Halliday, J.W.3
Powell, L.W.4
Brissot, P.5
-
98
-
-
0025663287
-
Analysis of iron-containing compounds in different compartments of the rat liver after iron loading
-
Ringeling PL, Cleton MI, Huijskes-Heins MI, Seip MJ, de Bruijn WC, van Eijk HG. Analysis of iron-containing compounds in different compartments of the rat liver after iron loading. Biol Met 1990;3:176-182
-
(1990)
Biol Met
, vol.3
, pp. 176-182
-
-
Ringeling, P.L.1
Cleton, M.I.2
Huijskes-Heins, M.I.3
Seip, M.J.4
De Bruijn, W.C.5
Van Eijk, H.G.6
-
99
-
-
0023655608
-
Siderosomal ferritin. The missing link between ferritin and haemosiderin?
-
Andrews SC, Treffry A, Harrison PM. Siderosomal ferritin. The missing link between ferritin and haemosiderin? Biochem J 1987;245:439-446
-
(1987)
Biochem J
, vol.245
, pp. 439-446
-
-
Andrews, S.C.1
Treffry, A.2
Harrison, P.M.3
-
100
-
-
0036182252
-
Denatured H-ferritin subunit is a major constituent of haemosiderin in the liver of patients with iron overload
-
Miyazaki E, Kato J, Kobune M, et al. Denatured H-ferritin subunit is a major constituent of haemosiderin in the liver of patients with iron overload. Gut 2002;50:413-419
-
(2002)
Gut
, vol.50
, pp. 413-419
-
-
Miyazaki, E.1
Kato, J.2
Kobune, M.3
-
101
-
-
45149142068
-
Hepatocyte iron release in rats
-
Beguin Y, Huebers HA, Weber G, Eng M, Finch CA. Hepatocyte iron release in rats. J Lab Clin Med 1989;113:346-354
-
(1989)
J Lab Clin Med
, vol.113
, pp. 346-354
-
-
Beguin, Y.1
Huebers, H.A.2
Weber, G.3
Eng, M.4
Finch, C.A.5
-
102
-
-
0033861745
-
A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation
-
McKie AT, Marciani P, Rolfs A, et al. A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. Mol Cell 2000;5:299-309
-
(2000)
Mol Cell
, vol.5
, pp. 299-309
-
-
McKie, A.T.1
Marciani, P.2
Rolfs, A.3
-
103
-
-
0034677467
-
Postional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
-
Donovan A, Brownlie A, Zhou Y, et al. Postional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature 2000;403:776-781
-
(2000)
Nature
, vol.403
, pp. 776-781
-
-
Donovan, A.1
Brownlie, A.2
Zhou, Y.3
-
104
-
-
0034733635
-
A novel mammalian iron-regulated protein involved in intracellular iron metabolism
-
Abboud S, Haile DJ. A novel mammalian iron-regulated protein involved in intracellular iron metabolism. J Biol Chem 2000;275:19906-19912
-
(2000)
J Biol Chem
, vol.275
, pp. 19906-19912
-
-
Abboud, S.1
Haile, D.J.2
-
105
-
-
1442306702
-
Non-HFE hemochromatosis
-
Pietrangelo A. Non-HFE hemochromatosis. Hepatology 2004;39:21-29
-
(2004)
Hepatology
, vol.39
, pp. 21-29
-
-
Pietrangelo, A.1
-
106
-
-
20444416123
-
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis
-
Donovan A, Lima CA, Pinkus JL, et al. The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metab 2005;1:191-200
-
(2005)
Cell Metab
, vol.1
, pp. 191-200
-
-
Donovan, A.1
Lima, C.A.2
Pinkus, J.L.3
-
107
-
-
1842504248
-
Aceruloplasminemia: An inherited neurodegenerative disease with impairment of iron homeostasis
-
Xu X, Pin S, Gathinji M, Fuchs R, Harris ZL. Aceruloplasminemia: an inherited neurodegenerative disease with impairment of iron homeostasis. Ann N Y Acad Sci 2004;1012:299-305
-
(2004)
Ann N Y Acad Sci
, vol.1012
, pp. 299-305
-
-
Xu, X.1
Pin, S.2
Gathinji, M.3
Fuchs, R.4
Harris, Z.L.5
-
108
-
-
0032875387
-
Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux
-
Harris ZL, Durley AP, Man TK, Gitlin JD. Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux. Proc Natl Acad Sci USA 1999;96:10812-10817
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10812-10817
-
-
Harris, Z.L.1
Durley, A.P.2
Man, T.K.3
Gitlin, J.D.4
-
109
-
-
14544298717
-
Hepcidin-a regulator of intestinal iron absorption and iron recycling by macrophages
-
Ganz T. Hepcidin-a regulator of intestinal iron absorption and iron recycling by macrophages. Best Pract Res Clin Haematol 2005;18:171-182
-
(2005)
Best Pract Res Clin Haematol
, vol.18
, pp. 171-182
-
-
Ganz, T.1
-
110
-
-
13544252463
-
Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia
-
Rivera S, Liu L, Nemeth E, Gabayan V, Sorensen OE, Ganz T. Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia. Blood 2005;105:1797-1802
-
(2005)
Blood
, vol.105
, pp. 1797-1802
-
-
Rivera, S.1
Liu, L.2
Nemeth, E.3
Gabayan, V.4
Sorensen, O.E.5
Ganz, T.6
-
111
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth E, Tuttle MS, Powelson J, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 2004;306:2090-2093
-
(2004)
Science
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
-
112
-
-
0025086248
-
Biliary excretion of iron in healthy man and in patients with alcoholic cirrhosis of the liver
-
Raedsch R, Stiehl A, Walker S, et al. Biliary excretion of iron in healthy man and in patients with alcoholic cirrhosis of the liver. Clin Chim Acta 1990;193:49-54
-
(1990)
Clin Chim Acta
, vol.193
, pp. 49-54
-
-
Raedsch, R.1
Stiehl, A.2
Walker, S.3
-
113
-
-
0024392124
-
Biliary excretion of iron and ferritin in idiopathic hemochromatosis
-
Hultcrantz R, Angelin B, Bjorn-Rasmussen E, Ewerth S, Einarsson K. Biliary excretion of iron and ferritin in idiopathic hemochromatosis. Gastroenterology 1989;96:1539-1545
-
(1989)
Gastroenterology
, vol.96
, pp. 1539-1545
-
-
Hultcrantz, R.1
Angelin, B.2
Bjorn-Rasmussen, E.3
Ewerth, S.4
Einarsson, K.5
-
114
-
-
0022559519
-
Biliary excretion of iron from hepatocyte lysosomes in the rat. A major excretory pathway in experimental iron overload
-
LeSage GD, Kost LJ, Barham SS, LaRusso NF. Biliary excretion of iron from hepatocyte lysosomes in the rat. A major excretory pathway in experimental iron overload. J Clin Invest 1986;77:90-97
-
(1986)
J Clin Invest
, vol.77
, pp. 90-97
-
-
Lesage, G.D.1
Kost, L.J.2
Barham, S.S.3
Larusso, N.F.4
-
115
-
-
0022624950
-
Ultrastructural evidence for the presence of ferritin-iron in the biliary system of patients with iron overload
-
Cleton MI, Sindram JW, Rademakers LH, Zuyderhoudt FM, De Bruijn WC, Marx JJ. Ultrastructural evidence for the presence of ferritin-iron in the biliary system of patients with iron overload. Hepatology 1986;6:30-35
-
(1986)
Hepatology
, vol.6
, pp. 30-35
-
-
Cleton, M.I.1
Sindram, J.W.2
Rademakers, L.H.3
Zuyderhoudt, F.M.4
De Bruijn, W.C.5
Marx, J.J.6
-
116
-
-
0028907384
-
Translocation of different forms of transferrin from blood to bile in the rat
-
Regoeczi E, Chindemi PA. Translocation of different forms of transferrin from blood to bile in the rat. Hepatology 1995;21:1063-1069
-
(1995)
Hepatology
, vol.21
, pp. 1063-1069
-
-
Regoeczi, E.1
Chindemi, P.A.2
-
117
-
-
0030913415
-
Intestinal absorption and enterohepatic cycling of biliary iron originating from plasma non-transferrin-bound iron in rats
-
Brissot P, Bolder U, Schteingart CD, Arnaud J, Hofmann AF. Intestinal absorption and enterohepatic cycling of biliary iron originating from plasma non-transferrin-bound iron in rats. Hepatology 1997;25:1457-1461
-
(1997)
Hepatology
, vol.25
, pp. 1457-1461
-
-
Brissot, P.1
Bolder, U.2
Schteingart, C.D.3
Arnaud, J.4
Hofmann, A.F.5
-
118
-
-
0035896581
-
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
-
Pigeon C, Ilyin G, Courselaud B, et al. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem 2001;276:7811-7819
-
(2001)
J Biol Chem
, vol.276
, pp. 7811-7819
-
-
Pigeon, C.1
Ilyin, G.2
Courselaud, B.3
-
119
-
-
0035902605
-
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
-
Nicolas G, Bennoun M, Devaux I, et al. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci USA 2001;98:8780-8785
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8780-8785
-
-
Nicolas, G.1
Bennoun, M.2
Devaux, I.3
-
120
-
-
2342425296
-
Changes in the expression of intestinal iron transport and hepatic regulatory molecules explain the enhanced iron absorption associated with pregnancy in the rat
-
Millard KN, Frazer DM, Wilkins SJ, Anderson GJ. Changes in the expression of intestinal iron transport and hepatic regulatory molecules explain the enhanced iron absorption associated with pregnancy in the rat. Gut 2004;53:655-660
-
(2004)
Gut
, vol.53
, pp. 655-660
-
-
Millard, K.N.1
Frazer, D.M.2
Wilkins, S.J.3
Anderson, G.J.4
-
121
-
-
0036791486
-
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
-
Nicolas G, Chauvet C, Viatte L, et al. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest 2002;110:1037-1044
-
(2002)
J Clin Invest
, vol.110
, pp. 1037-1044
-
-
Nicolas, G.1
Chauvet, C.2
Viatte, L.3
-
122
-
-
20244388240
-
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
-
Roetto A, Papanikolaou G, Politou M, et al. Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis. Nat Genet 2003;33:21-22
-
(2003)
Nat Genet
, vol.33
, pp. 21-22
-
-
Roetto, A.1
Papanikolaou, G.2
Politou, M.3
-
123
-
-
9344224529
-
A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
-
Feder JN, Gnirke A, Thomas W, et al. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet 1996;13:399-408
-
(1996)
Nat Genet
, vol.13
, pp. 399-408
-
-
Feder, J.N.1
Gnirke, A.2
Thomas, W.3
-
124
-
-
4744340782
-
Pathogenesis of hereditary hemochromatosis
-
Fleming RE, Britton RS, Waheed A, Sly WS, Bacon BR. Pathogenesis of hereditary hemochromatosis. Clin Liver Dis 2004;8:755-773
-
(2004)
Clin Liver Dis
, vol.8
, pp. 755-773
-
-
Fleming, R.E.1
Britton, R.S.2
Waheed, A.3
Sly, W.S.4
Bacon, B.R.5
-
125
-
-
0038312385
-
Decreased liver hepcidin expression in the Hfe knockout mouse
-
Ahmad KA, Ahmann JR, Migas MC, et al. Decreased liver hepcidin expression in the Hfe knockout mouse. Blood Cells Mol Dis 2002;29:361-366
-
(2002)
Blood Cells Mol Dis
, vol.29
, pp. 361-366
-
-
Ahmad, K.A.1
Ahmann, J.R.2
Migas, M.C.3
-
126
-
-
0037460697
-
Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis
-
Bridle KR, Frazer DM, Wilkins SJ, et al. Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet 2003;361:669-673
-
(2003)
Lancet
, vol.361
, pp. 669-673
-
-
Bridle, K.R.1
Frazer, D.M.2
Wilkins, S.J.3
-
128
-
-
13544250486
-
Hepcidin is decreased in TFR2 hemochromatosis
-
Nemeth E, Roetto A, Garozzo G, Ganz T, Camaschella C. Hepcidin is decreased in TFR2 hemochromatosis. Blood 2005;105:1803-1806
-
(2005)
Blood
, vol.105
, pp. 1803-1806
-
-
Nemeth, E.1
Roetto, A.2
Garozzo, G.3
Ganz, T.4
Camaschella, C.5
-
129
-
-
9144252017
-
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
-
Papanikolaou G, Samuels ME, Ludwig EH, et al. Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nat Genet 2004;36:77-82
-
(2004)
Nat Genet
, vol.36
, pp. 77-82
-
-
Papanikolaou, G.1
Samuels, M.E.2
Ludwig, E.H.3
-
130
-
-
0742322861
-
Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system
-
Niederkofler V, Salie R, Sigrist M, Arber S. Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system. J Neurosci 2004;24:808-818
-
(2004)
J Neurosci
, vol.24
, pp. 808-818
-
-
Niederkofler, V.1
Salie, R.2
Sigrist, M.3
Arber, S.4
-
131
-
-
20244375259
-
DRAGON, a bone morphogenetic protein co-receptor
-
Samad TA, Rebbapragada A, Bell E, et al. DRAGON, a bone morphogenetic protein co-receptor. J Biol Chem 2005;280:14122-14129
-
(2005)
J Biol Chem
, vol.280
, pp. 14122-14129
-
-
Samad, T.A.1
Rebbapragada, A.2
Bell, E.3
-
132
-
-
0037111732
-
Inappropriate expression of hepcidin is associated with iron refractory anemia: Implications for the anemia of chronic disease
-
Weinstein DA, Roy CN, Fleming MD, Loda MF, Wolfsdorf JI, Andrews NC. Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease. Blood 2002;100:3776-3781
-
(2002)
Blood
, vol.100
, pp. 3776-3781
-
-
Weinstein, D.A.1
Roy, C.N.2
Fleming, M.D.3
Loda, M.F.4
Wolfsdorf, J.I.5
Andrews, N.C.6
-
133
-
-
0036670737
-
Relationship between intestinal iron-transporter expression, hepatic hepcidin levels and the control of iron absorption
-
Anderson GJ, Frazer DM, Wilkins SJ, et al. Relationship between intestinal iron-transporter expression, hepatic hepcidin levels and the control of iron absorption. Biochem Soc Trans 2002;30:724-726
-
(2002)
Biochem Soc Trans
, vol.30
, pp. 724-726
-
-
Anderson, G.J.1
Frazer, D.M.2
Wilkins, S.J.3
-
134
-
-
3442875926
-
Increased hepcidin expression and hypoferraemia associated with an acute phase response are not affected by inactivation of HFE
-
Frazer DM, Wilkins SJ, Millard KN, McKie AT, Vulpe CD, Anderson GJ. Increased hepcidin expression and hypoferraemia associated with an acute phase response are not affected by inactivation of HFE. Br J Haematol 2004;126:434-436
-
(2004)
Br J Haematol
, vol.126
, pp. 434-436
-
-
Frazer, D.M.1
Wilkins, S.J.2
Millard, K.N.3
McKie, A.T.4
Vulpe, C.D.5
Anderson, G.J.6
-
135
-
-
3042636759
-
The IL-6- and lipopolysaccharide-induced transcription of hepcidin in HFE-, transferrin receptor 2-, and beta 2-microglobulin-deficient hepatocytes
-
Lee P, Peng H, Gelbart T, Beutler E. The IL-6- and lipopolysaccharide- induced transcription of hepcidin in HFE-, transferrin receptor 2-, and beta 2-microglobulin-deficient hepatocytes. Proc Natl Acad Sci USA 2004;101:9263-9265
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9263-9265
-
-
Lee, P.1
Peng, H.2
Gelbart, T.3
Beutler, E.4
-
136
-
-
2442426523
-
An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice
-
Roy CN, Custodio AO, de Graaf J, et al. An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice. Nat Genet 2004;36:481-485
-
(2004)
Nat Genet
, vol.36
, pp. 481-485
-
-
Roy, C.N.1
Custodio, A.O.2
De Graaf, J.3
|