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Volumn 31, Issue 3-4, 1999, Pages 499-508

Susceptibility of cultured rat hepatocytes to oxidative stress by peroxides and iron. The extracellular matrix affects the toxicity of tert-butyl hydroperoxide

Author keywords

Collagen; Extracellular matrix; Glutathione; Iron; Oxidative stress; Rat hepatocytes

Indexed keywords

COLLAGEN; DEFEROXAMINE; FERRITIN; GLUTATHIONE; IRON; LACTATE DEHYDROGENASE; MALONALDEHYDE; MANGANESE SUPEROXIDE DISMUTASE; PEROXIDE; SUPEROXIDE; TERT BUTYL HYDROPEROXIDE;

EID: 0032990360     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(98)00115-0     Document Type: Article
Times cited : (17)

References (19)
  • 3
    • 0026065734 scopus 로고
    • Iron mediates production of a neutrophil chemoattractant by rat hepatocytes metabolizing ethanol
    • Hultcrantz R., Bissell D.M., Roll F.J. Iron mediates production of a neutrophil chemoattractant by rat hepatocytes metabolizing ethanol. J. Clin. Invest. 87:1991;45-49.
    • (1991) J. Clin. Invest. , vol.87 , pp. 45-49
    • Hultcrantz, R.1    Bissell, D.M.2    Roll, F.J.3
  • 4
    • 0025243552 scopus 로고
    • Liver cell damage and lysosomal iron storage in patients with idiopathic hemochromatosis. A light and electron microscopic study
    • Stål P., Hultcrantz R., Glaumann H. Liver cell damage and lysosomal iron storage in patients with idiopathic hemochromatosis. A light and electron microscopic study. J. Hepatol. 11:1990;172-180.
    • (1990) J. Hepatol. , vol.11 , pp. 172-180
    • Stål, P.1    Hultcrantz, R.2    Glaumann, H.3
  • 5
    • 33746521801 scopus 로고
    • The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies
    • Friedman S.L. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies. NEJM. 24:1993;1828-1835.
    • (1993) NEJM , vol.24 , pp. 1828-1835
    • Friedman, S.L.1
  • 6
    • 0026322220 scopus 로고
    • Reduced and oxidized glutathione contents in adult rat hepatocytes under various culture conditions
    • Mertens K., Roigers V., Sonck W., Vercruysse A. Reduced and oxidized glutathione contents in adult rat hepatocytes under various culture conditions. Cell Biol. Toxicol. 7:1991;101-110.
    • (1991) Cell Biol. Toxicol. , vol.7 , pp. 101-110
    • Mertens, K.1    Roigers, V.2    Sonck, W.3    Vercruysse, A.4
  • 7
    • 0028334997 scopus 로고
    • The role of thiols in mitochondrial susceptibility to iron and tert-butyl hydroperoxide-mediated toxicity in cultured mouse hepatocytes
    • Shertzer H.G., Bannenberg G.L., Zhu H., Liu R.-M., Moldeus P. The role of thiols in mitochondrial susceptibility to iron and tert-butyl hydroperoxide-mediated toxicity in cultured mouse hepatocytes. Chem. Res. Toxicol. 7:1994;358-366.
    • (1994) Chem. Res. Toxicol. , vol.7 , pp. 358-366
    • Shertzer, H.G.1    Bannenberg, G.L.2    Zhu, H.3    Liu, R.-M.4    Moldeus, P.5
  • 8
    • 0030863299 scopus 로고    scopus 로고
    • Nutrient deprivation of cultured rat hepatocytes increases the desferrioxamine-available iron pool and augments the sensitivity to hydrogen peroxide
    • Öllinger K., Roberg K. Nutrient deprivation of cultured rat hepatocytes increases the desferrioxamine-available iron pool and augments the sensitivity to hydrogen peroxide. J. Biol. Chem. 272(38):1997;23707-23711.
    • (1997) J. Biol. Chem. , vol.272 , Issue.38 , pp. 23707-23711
    • Öllinger, K.1    Roberg, K.2
  • 9
    • 0025358379 scopus 로고
    • Prevention of hepatocyte injury and lipid peroxidation by iron chelators and α-tocopherol in isolated iron-loaded rat hepatocytes
    • Sharma B.K., Bacon B.R., Britton R.S., Park C.H., Magiera C.J., O'Neill R., Dalton N., Smanik P., Speroff T. Prevention of hepatocyte injury and lipid peroxidation by iron chelators and α-tocopherol in isolated iron-loaded rat hepatocytes. Hepatology. 12(1):1990;31-39.
    • (1990) Hepatology , vol.12 , Issue.1 , pp. 31-39
    • Sharma, B.K.1    Bacon, B.R.2    Britton, R.S.3    Park, C.H.4    Magiera, C.J.5    O'Neill, R.6    Dalton, N.7    Smanik, P.8    Speroff, T.9
  • 10
    • 0030272970 scopus 로고    scopus 로고
    • Hepatotoxicity induced by iron overload and alcohol. Studies on the role of chelatable iron, cytochrome P450 2E1 and lipid peroxidation
    • Stål P., Johansson I., Ingelman-Sundberg M., Hagen K., Hultcrantz R. Hepatotoxicity induced by iron overload and alcohol. Studies on the role of chelatable iron, cytochrome P450 2E1 and lipid peroxidation. J. Hepatol. 25:1996;538-546.
    • (1996) J. Hepatol. , vol.25 , pp. 538-546
    • Stål, P.1    Johansson, I.2    Ingelman-Sundberg, M.3    Hagen, K.4    Hultcrantz, R.5
  • 11
    • 0027435650 scopus 로고
    • Chronic feeding of carbonyl-iron and TMH-ferrocene in rats. Comparison of two iron-overload models with different iron absorption
    • Nielsen P., Heinelt S., Dullmann J. Chronic feeding of carbonyl-iron and TMH-ferrocene in rats. Comparison of two iron-overload models with different iron absorption. Comp. Biochem. Physiol. C. 106(2):1993;429-436.
    • (1993) Comp. Biochem. Physiol. C , vol.106 , Issue.2 , pp. 429-436
    • Nielsen, P.1    Heinelt, S.2    Dullmann, J.3
  • 12
    • 0020039871 scopus 로고
    • Studies on the rat liver following iron overload. Biochemical studies after iron mobilization
    • Hultcrantz R., Glaumann H. Studies on the rat liver following iron overload. Biochemical studies after iron mobilization. Lab. Invest. 46:1982;383-393.
    • (1982) Lab. Invest. , vol.46 , pp. 383-393
    • Hultcrantz, R.1    Glaumann, H.2
  • 13
    • 0021712273 scopus 로고
    • Free malonaldehyde determination in tissues by high-perfomance liquid chromatography
    • Csallany A.S., Guan D.M., Manwaring J.D., Addis P.B. Free malonaldehyde determination in tissues by high-perfomance liquid chromatography. Anal. Biochem. 142:1984;277-283.
    • (1984) Anal. Biochem. , vol.142 , pp. 277-283
    • Csallany, A.S.1    Guan, D.M.2    Manwaring, J.D.3    Addis, P.B.4
  • 14
    • 0027052233 scopus 로고
    • Loss of suppression of GSH synthesis at low cell density in primary cultures of rat hepatocytes
    • Lu S.C., Ge J.-L. Loss of suppression of GSH synthesis at low cell density in primary cultures of rat hepatocytes. Am. J. Physiol. 263(Cell Physiol. 32):1992;C1181-C1189.
    • (1992) Am. J. Physiol. , vol.263 , Issue.CELL PHYSIOL. 32
    • Lu, S.C.1    Ge, J.-L.2
  • 15
    • 0023090714 scopus 로고
    • Support of cultured hepatocytes by a laminin-rich gel: Evidence for a functionally significant subendothelial matrix in normal rat liver
    • Bissell D.M., Arenson D.M., Maher J.J., Roll F.J. Support of cultured hepatocytes by a laminin-rich gel: evidence for a functionally significant subendothelial matrix in normal rat liver. J. Clin. Invest. 79:1987;801-812.
    • (1987) J. Clin. Invest. , vol.79 , pp. 801-812
    • Bissell, D.M.1    Arenson, D.M.2    Maher, J.J.3    Roll, F.J.4
  • 16
    • 0023607035 scopus 로고
    • Hepatic heme synthesis in a new model of experimental hemochromatosis: Studies in rat fed finely divided elemental iron
    • Bonkovsky H.L., Healey J.F., Lincoln B., Bacon B.R., Bishop D.F., Elder G.H. Hepatic heme synthesis in a new model of experimental hemochromatosis: Studies in rat fed finely divided elemental iron. Hepatology. 7:1987;1195-1203.
    • (1987) Hepatology , vol.7 , pp. 1195-1203
    • Bonkovsky, H.L.1    Healey, J.F.2    Lincoln, B.3    Bacon, B.R.4    Bishop, D.F.5    Elder, G.H.6
  • 17
    • 0026803380 scopus 로고
    • Evaluation of iron binding and peroxide-mediated toxicity in rat hepatocytes
    • Shertzer H.G., Bannenberg G.L., Moldeus P. Evaluation of iron binding and peroxide-mediated toxicity in rat hepatocytes. Biochem. Pharmacol. 44(7):1992;1367-1373.
    • (1992) Biochem. Pharmacol. , vol.44 , Issue.7 , pp. 1367-1373
    • Shertzer, H.G.1    Bannenberg, G.L.2    Moldeus, P.3
  • 18
    • 0025290814 scopus 로고
    • Kinetic evaluation of free malondialdehyde and enzyme leakage as indices of iron damage in rat hepatocyte cultures
    • Morel I., Lescoat G., Cillard J., Pasdeloup N., Brissot P., Cillard P. Kinetic evaluation of free malondialdehyde and enzyme leakage as indices of iron damage in rat hepatocyte cultures. Biochem. Pharmacol. 39(11):1990;1647-1655.
    • (1990) Biochem. Pharmacol. , vol.39 , Issue.11 , pp. 1647-1655
    • Morel, I.1    Lescoat, G.2    Cillard, J.3    Pasdeloup, N.4    Brissot, P.5    Cillard, P.6
  • 19
    • 0026706945 scopus 로고
    • Antioxidants and free radical scavenging activities of the iron chelators pyoverdin and hydroxypyrid-4-ones in iron-loaded hepatocyte cultures: Comparison of their mechanism of protection with that of desferrioxamine
    • Morel I., Cillard J., Lescoat G., Sergent O., Pasdeloup N., Ocaktan A.Z., Abdallah M.A., Brissot P., Cillard P. Antioxidants and free radical scavenging activities of the iron chelators pyoverdin and hydroxypyrid-4-ones in iron-loaded hepatocyte cultures: Comparison of their mechanism of protection with that of desferrioxamine. Free Radical Biol. Med. 13:1992;499-508.
    • (1992) Free Radical Biol. Med. , vol.13 , pp. 499-508
    • Morel, I.1    Cillard, J.2    Lescoat, G.3    Sergent, O.4    Pasdeloup, N.5    Ocaktan, A.Z.6    Abdallah, M.A.7    Brissot, P.8    Cillard, P.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.