Iron and hepatocellular carcinoma

Journal of Gastroenterology and Hepatology (Australia)

Volumn 16, Issue 5, 2001, Pages 491-494

  Deugnier, Yves ^a   Turlin, Bruno ^a  

^a PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; DNA; FREE RADICAL; IRON; LIPID; REACTIVE OXYGEN METABOLITE;

ALCOHOL LIVER CIRRHOSIS; CANCER DIAGNOSIS; CANCER GROWTH; CANCER INCIDENCE; CANCER MORTALITY; CANCER RISK; CLINICAL FEATURE; DISEASE ASSOCIATION; EXPERIMENTAL NEOPLASM; GENETIC DISORDER; HEMOCHROMATOSIS; HEPATITIS B; HUMAN; IRON BLOOD LEVEL; IRON INTAKE; IRON OVERLOAD; LIPID PEROXIDATION; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LYMPHOCYTE PROLIFERATION; NONHUMAN; OXIDATIVE STRESS; PORPHYRIA CUTANEA TARDA; PRIORITY JOURNAL; REVIEW; TUMOR GROWTH;

EID: 0035722280     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1746.2001.02430.x     Document Type: Review

References (45)

1. Long-term survival in patients with hereditary hemochromatosis
2. Survival and prognostic factors in 212 Italian patients with genetic hemochromatosis
3. Cohort study of internal malignancy in genetic hemochromatosis and other chronic non-alcoholic liver disease
4. Survival and causes of death in cirrhotic and non cirrhotic patients with primary hemochromatosis
5. Primary liver cancer in genetic hemochromatosis: A clinical, pathological and pathogenetic study of 54 cases
6. Prognostic factors for hepatocellular carcinoma in genetic hemochromatosis
7. Magnetic resonance of iron-free nodules in genetic hemochromatosis
8. Liver pathology in genetic hemochromatosis: A review of 135 homozygous cases and their bio-clinical correlations
9. Pre-neoplastic significance of hepatic iron-free foci in genetic hemochromatosis: A study of 185 patients
10. p53 mutations in British patients with hepatocellular carcinoma: Clustering in genetic hemochromatosis
11. Hepatocellular carcinoma arising in the absence of cirrhosis in genetic haemochromatosis: Three case reports and review of literature
12. Non-transferrin bound iron in plasma from haemochromatosis patients: Effect of phlebotomy therapy
13. Hemosiderosis in cirrhosis: A study of 447 native livers
14. Iron and neoplasia
15. Iron as a carcinogen
16. Iron-accumulating adenomatous hyperplastic nodule with malignant foci in the cirrhotic liver. Histopathologic, quantitative iron, and magnetic resonance imaging in vitro studies
17. Hepatocellular carcinoma: Association with increased iron deposition in the cirrhotic liver at MR imaging
18. Increased liver iron stores in patients with hepatocellular carcinoma developed on a non-cirrhotic liver
19. Premalignant lesions and hepatocellular carcinoma in a non-cirrhotic alcoholic patient with iron overload and normal transferrin saturation
20. The effects of dietary iron on initiation and promotion in chemical hepatocarcinogenesis
21. Chronic iron overload in rats induces oval cells in the liver
22. Carbonyl iron supplementation induces hepatocyte nuclear changes in BALB/cJ male mice
23. Hemosiderosis in Lemurs
24. Hepatopathy associated with excessive iron storage in Mynah birds
25. Copper-overload causes cancer? The LEC rat: A model for human hepatitis, liver cancer, and much more
26. Beta2 knockout mice develop parenchymal iron overload: A putative role for class I genes of the major histocompatibility complex in iron metabolism
27. Iron may induce both DNA synthesis and repair in rat hepatocytes stimulated by EGF/pyruvate
28. Effect of iron and desferoxamine on cell growth and in vitro ferritin synthesis in human hepatoma cell lines
29. Neuroblastoma sensitivity to growth inhibition by deferoxamine: Evidence for a block in G1 phase of the cell cycle
30. Iron, ferritin, hepatitis B surface and core antigens in the livers of Chinese patients with hepatocellular carcinoma
31. Absence of stainable iron from pre-neoplastic and neoplastic lesions in rat liver with 8-hydroxyquinoline-induced siderosis
32. Iron-induced carcinogenesis: The role of redox regulation
33. Iron-induced tissue damage and cancer: The role of reactive oxygen species-free radicals
34. DNA base modifications in renal chromatin of Wistar rats treated with a renal carcinogen, ferric nitrilotriacetate
35. Repair of DNA damage induced by reactive oxygen species
36. Mutagenesis by the autooxydation of iron with isolated DNA
37. Determination of non-transferrin-bound iron in genetic hemochromatosis using a new HPLC-based method
38. Antioxydant status and lipid peroxidation in hereditary haemochromatosis
39. Excess iron induces hepatic oxydative stress and transforming growth factor β1 in genetic hemochromatosis
40. Lymphocyte proliferation is controlled by both iron availability and regulation of iron uptake pathways
41. Effect of transferrin, lactoferrin and chelated iron on human T-lymphocytes
42. T-lymphocyte expression and function in hemochromatosis
43. Suppressive effect of ferritin on in vitro lymphocyte function
44. Ferritin selectively suppresses delayed-type hypersensitivity responses at induction or effecter phase
45. Iron inhibits the nonspecific tumoricidal activity of macrophages. A possible contributory mechanism for neoplasia in hemochromatosis