Iron restriction improves type 2 diabetes mellitus in Otsuka Long-Evans Tokushima fatty rats

American Journal of Physiology - Endocrinology and Metabolism

Volumn 298, Issue 6, 2010, Pages

  Minamiyama, Yukiko ^a,b   Takemura, Shigekazu ^b   Kodai, Shintaro ^b   Shinkawa, Hiroji ^b   Tsukioka, Takuma ^b   Ichikawa, Hiroshi ^c   Naito, Yuji ^a   Yoshikawa, Toshikazu ^a   Okada, Shigeru ^d  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c DOSHISHA UNIVERSITY   (Japan)

^d OKAYAMA UNIVERSITY   (Japan)

Author keywords

Diabetes; Iron depletion; Oxidative stress; Pancreatic fibrosis; Pancreatic peroxisome proliferator activated receptor

Indexed keywords

ALCOHOL; FATTY ACID; FERRITIN; GLUCOSE; HEMOGLOBIN A1C; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; SUPEROXIDE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CYSTIC FIBROSIS; DIETARY INTAKE; FERRITIN BLOOD LEVEL; INSULIN BLOOD LEVEL; IRON DEPLETION; IRON OVERLOAD; IRON RESTRICTION; LIPID PEROXIDATION; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEOTIDE SEQUENCE; OTSUKA LONG EVANS TOKUSHIMA FATTY RAT; OXIDATIVE STRESS; PHLEBOTOMY; PRIORITY JOURNAL; RAT;

ANIMALS; DIABETES MELLITUS, TYPE 2; FERRITINS; GENE EXPRESSION; HEMOGLOBIN A, GLYCOSYLATED; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; INSULIN; IRON; LIVER; MALE; MALONDIALDEHYDE; OXIDATIVE STRESS; PANCREAS; PPAR DELTA; RATS; RATS, INBRED OLETF; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA;

EID: 77952628680     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00620.2009     Document Type: Article

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