메뉴 건너뛰기




Volumn 45, Issue 4, 2013, Pages 241-258

Recognition of pathogen-associated nucleic acids by endosomal nucleic acid-sensing toll-like receptors

Author keywords

Compartmentalization; Danger signal; Endosomal nucleic acidsensing toll like receptor; Innate immunity; Signaling pathway

Indexed keywords

NUCLEIC ACID; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9;

EID: 84879231418     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1093/abbs/gms122     Document Type: Review
Times cited : (31)

References (190)
  • 1
    • 79956300649 scopus 로고    scopus 로고
    • Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
    • Kawai T and Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 2011, 34: 637-650.
    • (2011) Immunity , vol.34 , pp. 637-650
    • Kawai, T.1    Akira, S.2
  • 3
    • 79958205445 scopus 로고    scopus 로고
    • Sensing disease and danger: A survey of vertebrate PRRs and their origins
    • Hansena JD, Vojtechb LN and Laingc KJ. Sensing disease and danger: a survey of vertebrate PRRs and their origins. Dev Comp Immunol 2011, 35: 886-897.
    • (2011) Dev Comp Immunol , vol.35 , pp. 886-897
    • Hansena, J.D.1    Vojtechb, L.N.2    Laingc, K.J.3
  • 4
    • 79959447465 scopus 로고    scopus 로고
    • Structural biology of the toll-like receptor family
    • Kang JY and Lee JO. Structural biology of the toll-like receptor family. Annu Rev Biochem 2011, 80: 917-941.
    • (2011) Annu Rev Biochem , vol.80 , pp. 917-941
    • Kang, J.Y.1    Lee, J.O.2
  • 5
    • 68849085894 scopus 로고    scopus 로고
    • A cell biological view of Toll-like receptor function: Regulation through compartmentalization
    • Barton GM and Kagan JC. A cell biological view of Toll-like receptor function: regulation through compartmentalization. Nat Rev Immunol 2009, 9: 535-542.
    • (2009) Nat Rev Immunol , vol.9 , pp. 535-542
    • Barton, G.M.1    Kagan, J.C.2
  • 6
    • 79953052004 scopus 로고    scopus 로고
    • Antiviral responses induced by the TLR3 pathway
    • Matsumoto M, Oshiumi H and Seya T. Antiviral responses induced by the TLR3 pathway. Rev Med Virol 2011, 21: 67-77.
    • (2011) Rev Med Virol , vol.21 , pp. 67-77
    • Matsumoto, M.1    Oshiumi, H.2    Seya, T.3
  • 7
    • 79251563125 scopus 로고    scopus 로고
    • Current views of Toll-like receptor signaling pathways
    • Yamamoto M and Takeda K. Current views of Toll-like receptor signaling pathways. Gastroent Res Pract 2010, 2010: 240365.
    • (2010) Gastroent Res Pract , vol.2010 , pp. 240365
    • Yamamoto, M.1    Takeda, K.2
  • 8
    • 84859488146 scopus 로고    scopus 로고
    • PACSIN1 regulates the TLR7/9-mediated type i interferon response in plasmacytoid dendritic cells
    • Esashi E, Bao M, Wang YH, Cao W and Liu YJ. PACSIN1 regulates the TLR7/9-mediated type I interferon response in plasmacytoid dendritic cells. Eur J Immunol 2012, 42: 573-579.
    • (2012) Eur J Immunol , vol.42 , pp. 573-579
    • Esashi, E.1    Bao, M.2    Wang, Y.H.3    Cao, W.4    Liu, Y.J.5
  • 9
    • 69949093459 scopus 로고    scopus 로고
    • Direct activation of protein kinases by unanchored polyubiquitin chains
    • Xia ZP, Sun L, Chen X, Pineda G, Jiang X, Adhikari A and Zeng W, et al. Direct activation of protein kinases by unanchored polyubiquitin chains. Nature 2009, 461: 114-9.
    • (2009) Nature , vol.461 , pp. 114-119
    • Xia, Z.P.1    Sun, L.2    Chen, X.3    Pineda, G.4    Jiang, X.5    Adhikari, A.6    Zeng, W.7
  • 10
    • 33750064259 scopus 로고    scopus 로고
    • Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptordependent gene induction program
    • Negishi H, Fujita Y, Yanai H, Sakaguchi S, Ouyang X, Shinohara M and Takayanagi H, et al. Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptordependent gene induction program. Proc Natl Acad Sci USA 2006, 103: 15136-15141.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 15136-15141
    • Negishi, H.1    Fujita, Y.2    Yanai, H.3    Sakaguchi, S.4    Ouyang, X.5    Shinohara, M.6    Takayanagi, H.7
  • 11
    • 84857846174 scopus 로고    scopus 로고
    • Activation of interferon regulatory factor 5 by site specific phosphorylation
    • Chang Foreman HC, Van Scoy S, Cheng TF and Reich NC. Activation of interferon regulatory factor 5 by site specific phosphorylation. PLoS One 2012, 7: e33098.
    • (2012) PLoS One , vol.7
    • Chang Foreman, H.C.1    Van Scoy, S.2    Cheng, T.F.3    Reich, N.C.4
  • 12
    • 77950883727 scopus 로고    scopus 로고
    • Toll-like receptor 8-mediated activation of murine plasmacytoid dendritic cells by vaccinia viral DNA
    • Martinez J, Huang X and Yang Y. Toll-like receptor 8-mediated activation of murine plasmacytoid dendritic cells by vaccinia viral DNA. Proc Natl Acad Sci USA 2010, 107: 6442-6447.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 6442-6447
    • Martinez, J.1    Huang, X.2    Yang, Y.3
  • 13
    • 79953020324 scopus 로고    scopus 로고
    • A novel Toll-like receptor that recognizes vesicular stomatitis virus
    • Shi Z, Cai Z, Sanchez A, Zhang T, Wen S, Wang J and Yang JH, et al. A novel Toll-like receptor that recognizes vesicular stomatitis virus. J Biol Chem 2011, 286: 4517-4524.
    • (2011) J Biol Chem , vol.286 , pp. 4517-4524
    • Shi, Z.1    Cai, Z.2    Sanchez, A.3    Zhang, T.4    Wen, S.5    Wang, J.6    Yang, J.H.7
  • 14
    • 84865571191 scopus 로고    scopus 로고
    • TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification
    • Oldenburg M, Krüger A, Ferstl R, Kaufmann A, Nees G, Sigmund A and Bathke B, et al. TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification. Science 2012, 337: 1111-1115.
    • (2012) Science , vol.337 , pp. 1111-1115
    • Oldenburg, M.1    Krüger, A.2    Ferstl, R.3    Kaufmann, A.4    Nees, G.5    Sigmund, A.6    Bathke, B.7
  • 21
    • 79959634861 scopus 로고    scopus 로고
    • Pattern recognition receptors and the innate immune response to viral infection
    • Thompson MR, Kaminski JJ, Kurt-Jones EA and Fitzgerald KA. Pattern recognition receptors and the innate immune response to viral infection. Viruses 2011, 3: 920-940.
    • (2011) Viruses , vol.3 , pp. 920-940
    • Thompson, M.R.1    Kaminski, J.J.2    Kurt-Jones, E.A.3    Fitzgerald, K.A.4
  • 22
    • 0037738569 scopus 로고    scopus 로고
    • Toll-like receptor expression in murine DC subsets: Lack of TLR7 expression by CD8 alpha- DC correlates with unresponsiveness to imidazoquinolines
    • Edwards AD, Diebold SS, Slack EM, Tomizawa H, Hemmi H, Kaisho T and Akira S, et al. Toll-like receptor expression in murine DC subsets: Lack of TLR7 expression by CD8 alpha- DC correlates with unresponsiveness to imidazoquinolines. Eur J Immunol 2003, 33: 827-833.
    • (2003) Eur J Immunol , vol.33 , pp. 827-833
    • Edwards, A.D.1    Diebold, S.S.2    Slack, E.M.3    Tomizawa, H.4    Hemmi, H.5    Kaisho, T.6    Akira, S.7
  • 23
    • 78650655879 scopus 로고    scopus 로고
    • Monocyte-mediated inhibition of TLR9-dependent IFN-α induction in plasmacytoid dendritic cells questions bacterial DNA as the active ingredient of bacterial lysates
    • Poth JM, Coch C, Busch N, Boehm O, Schlee M, Janke M and Zillinger T, et al. Monocyte-mediated inhibition of TLR9-dependent IFN-α induction in plasmacytoid dendritic cells questions bacterial DNA as the active ingredient of bacterial lysates. J Immunol 2010, 185: 7367-7373.
    • (2010) J Immunol , vol.185 , pp. 7367-7373
    • Poth, J.M.1    Coch, C.2    Busch, N.3    Boehm, O.4    Schlee, M.5    Janke, M.6    Zillinger, T.7
  • 25
    • 65749104837 scopus 로고    scopus 로고
    • How location governs toll-like receptor signaling
    • Chaturvedi A and Pierce SK. How location governs toll-like receptor signaling. Traffic 2009, 10: 621-628.
    • (2009) Traffic , vol.10 , pp. 621-628
    • Chaturvedi, A.1    Pierce, S.K.2
  • 26
    • 62849109129 scopus 로고    scopus 로고
    • TLR9 traffics through the Golgi complex to localize to endolysosomes and respond to CpG DNA
    • Chockalingam A, Brooks JC, Cameron JL, Blum LK and Leifer CA. TLR9 traffics through the Golgi complex to localize to endolysosomes and respond to CpG DNA. Immunol Cell Biol 2009, 87: 209-217.
    • (2009) Immunol Cell Biol , vol.87 , pp. 209-217
    • Chockalingam, A.1    Brooks, J.C.2    Cameron, J.L.3    Blum, L.K.4    Leifer, C.A.5
  • 28
    • 29244450802 scopus 로고    scopus 로고
    • Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA
    • Barton GM, Kagan JC and Medzhitov R. Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA. Nat Immunol 2006, 7: 49-56.
    • (2006) Nat Immunol , vol.7 , pp. 49-56
    • Barton, G.M.1    Kagan, J.C.2    Medzhitov, R.3
  • 29
    • 84862804952 scopus 로고    scopus 로고
    • Accessory molecules for Toll-like receptors and their function
    • Lee CC, Avalos AM and Ploegh HL. Accessory molecules for Toll-like receptors and their function. Nat Rev Immunol 2012, 12: 168-179.
    • (2012) Nat Rev Immunol , vol.12 , pp. 168-179
    • Lee, C.C.1    Avalos, A.M.2    Ploegh, H.L.3
  • 30
    • 84859027576 scopus 로고    scopus 로고
    • Autophagy in regulation of Toll-like receptor signaling
    • Into T, Inomata M, Takayama E and Takigawa T. Autophagy in regulation of Toll-like receptor signaling. Cell Signal 2012, 24: 1150-1162.
    • (2012) Cell Signal , vol.24 , pp. 1150-1162
    • Into, T.1    Inomata, M.2    Takayama, E.3    Takigawa, T.4
  • 31
    • 58049209832 scopus 로고    scopus 로고
    • Regulatory molecules required for nucleotidesensing toll-like receptors
    • Saitoh S and Miyake K. Regulatory molecules required for nucleotidesensing toll-like receptors. Immunol Rev 2009, 227: 32-43.
    • (2009) Immunol Rev , vol.227 , pp. 32-43
    • Saitoh, S.1    Miyake, K.2
  • 32
    • 27744526784 scopus 로고    scopus 로고
    • TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements
    • Nishiya T, Kajita E, Miwa S and Defranco A. TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements. J Biol Chem 2005, 280: 37107-37117.
    • (2005) J Biol Chem , vol.280 , pp. 37107-37117
    • Nishiya, T.1    Kajita, E.2    Miwa, S.3    Defranco, A.4
  • 34
    • 81955161805 scopus 로고    scopus 로고
    • Transmembrane mutations in Toll-like receptor 9 bypass the requirement for ectodomain proteolysis and induce fatal inflammation
    • Mouchess ML, Arpaia N, Souza G, Barbalat R, Ewald SE, Lau L and Barton GM. Transmembrane mutations in Toll-like receptor 9 bypass the requirement for ectodomain proteolysis and induce fatal inflammation. Immunity 2011, 35: 721-732.
    • (2011) Immunity , vol.35 , pp. 721-732
    • Mouchess, M.L.1    Arpaia, N.2    Souza, G.3    Barbalat, R.4    Ewald, S.E.5    Lau, L.6    Barton, G.M.7
  • 35
    • 33847260278 scopus 로고    scopus 로고
    • Heat shock protein gp96 is a master chaperones for toll-like receptors and is important in the innate function of macrophages
    • Yang Y, Liu B, Dai J, Srivastava PK, Zammit DJ, Lefrançois L and Li Z, et al. Heat shock protein gp96 is a master chaperones for toll-like receptors and is important in the innate function of macrophages. Immunity 2007a, 26: 215-226.
    • (2007) Immunity , vol.26 , pp. 215-226
    • Yang, Y.1    Liu, B.2    Dai, J.3    Srivastava, P.K.4    Zammit, D.J.5    Lefrançois, L.6    Li, Z.7
  • 36
    • 84861221245 scopus 로고    scopus 로고
    • Heat shock protein gp96 regulates Toll-like receptor 9 proteolytic processing and conformational stability
    • Brooks JC, Sun W, Chiosis G and Leifer CA. Heat shock protein gp96 regulates Toll-like receptor 9 proteolytic processing and conformational stability. Biochem Biophys Res Commun 2012, 421: 780-784.
    • (2012) Biochem Biophys Res Commun , vol.421 , pp. 780-784
    • Brooks, J.C.1    Sun, W.2    Chiosis, G.3    Leifer, C.A.4
  • 37
    • 54949103603 scopus 로고    scopus 로고
    • A single base mutation in the PRAT4A gene reveals differential interaction of PRAT4A with Toll-like receptors
    • Kiyokawa T, Akashi-Takamura S, Shibata T, Matsumoto F, Nishitani C, Kuroki Y and Seto Y, et al. A single base mutation in the PRAT4A gene reveals differential interaction of PRAT4A with Toll-like receptors. Int Immunol 2008, 20: 1407-1415.
    • (2008) Int Immunol , vol.20 , pp. 1407-1415
    • Kiyokawa, T.1    Akashi-Takamura, S.2    Shibata, T.3    Matsumoto, F.4    Nishitani, C.5    Kuroki, Y.6    Seto, Y.7
  • 38
    • 84857475033 scopus 로고    scopus 로고
    • Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substratespecific cochaperone
    • Liu B, Yang Y, Qiu ZJ, Staron M, Hong F, Li Y and Wu S, et al. Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substratespecific cochaperone. Nat Commun 2010, 1: 1-10.
    • (2010) Nat Commun , vol.1 , pp. 1-10
    • Liu, B.1    Yang, Y.2    Qiu, Z.J.3    Staron, M.4    Hong, F.5    Li, Y.6    Wu, S.7
  • 39
    • 78649877815 scopus 로고    scopus 로고
    • Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
    • Blasius AL, Arnold CN, Georgel P, Rutschmann S, Xia Y, Lin P and Ross C, et al. Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells. Proc Natl Acad Sci USA 2010, 107: 19973-19978.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 19973-19978
    • Blasius, A.L.1    Arnold, C.N.2    Georgel, P.3    Rutschmann, S.4    Xia, Y.5    Lin, P.6    Ross, C.7
  • 42
    • 34247484007 scopus 로고    scopus 로고
    • The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling
    • Brinkmann MM, Spooner E, Hoebe K, Beutler B, Ploegh HL and Kim YM. The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling. J Cell Biol 2007, 177: 265-275.
    • (2007) J Cell Biol , vol.177 , pp. 265-275
    • Brinkmann, M.M.1    Spooner, E.2    Hoebe, K.3    Beutler, B.4    Ploegh, H.L.5    Kim, Y.M.6
  • 43
    • 40749098665 scopus 로고    scopus 로고
    • UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
    • Kim YM, Brinkmann MM, Paquet ME and Ploegh HL. UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes. Nature 2008, 452: 234-238.
    • (2008) Nature , vol.452 , pp. 234-238
    • Kim, Y.M.1    Brinkmann, M.M.2    Paquet, M.E.3    Ploegh, H.L.4
  • 44
    • 67449136127 scopus 로고    scopus 로고
    • Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA-but against RNA-sensing
    • Fukui R, Saitoh S, Matsumoto F, Kozuka-Hata H, Oyama M, Tabeta K and Beutler B, et al. Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA-but against RNA-sensing. J Exp Med 2009, 206: 1339-1350.
    • (2009) J Exp Med , vol.206 , pp. 1339-1350
    • Fukui, R.1    Saitoh, S.2    Matsumoto, F.3    Kozuka-Hata, H.4    Oyama, M.5    Tabeta, K.6    Beutler, B.7
  • 45
    • 31344466165 scopus 로고    scopus 로고
    • The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3 7 and 9
    • Tabeta K, Hoebe K, Janssen EM, Du X, Georgel P, Crozat K and Mudd S, et al. The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol 2006, 7: 156-164.
    • (2006) Nat Immunol , vol.7 , pp. 156-164
    • Tabeta, K.1    Hoebe, K.2    Janssen, E.M.3    Du, X.4    Georgel, P.5    Crozat, K.6    Mudd, S.7
  • 47
    • 79960470158 scopus 로고    scopus 로고
    • Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking
    • Fukui R, Saitoh S, Kanno A, Onji M, Shibata T, Ito A and Onji M, et al. Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking. Immunity 2011, 35: 69-81.
    • (2011) Immunity , vol.35 , pp. 69-81
    • Fukui, R.1    Saitoh, S.2    Kanno, A.3    Onji, M.4    Shibata, T.5    Ito, A.6    Onji, M.7
  • 48
    • 84862683427 scopus 로고    scopus 로고
    • UNC93B1 mediates innate inflammation and antiviral defense in the liver during acute murine cytomegalovirus infection
    • Crane MJ, Gaddi PJ and Salazar-Mather TP. UNC93B1 mediates innate inflammation and antiviral defense in the liver during acute murine cytomegalovirus infection. PLoS One 2012, 7: e39161.
    • (2012) PLoS One , vol.7
    • Crane, M.J.1    Gaddi, P.J.2    Salazar-Mather, T.P.3
  • 49
  • 51
    • 56349114913 scopus 로고    scopus 로고
    • Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9
    • Park B, Brinkmann MM, Spooner E, Lee CC, Kim YM and Ploegh HL. Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9. Nat Immunol 2008, 9: 1407-1414.
    • (2008) Nat Immunol , vol.9 , pp. 1407-1414
    • Park, B.1    Brinkmann, M.M.2    Spooner, E.3    Lee, C.C.4    Kim, Y.M.5    Ploegh, H.L.6
  • 53
    • 38849127573 scopus 로고    scopus 로고
    • Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis
    • Asagiri M, Hirai T, Kunigami T, Kamano S, Gober HJ, Okamoto K and Nishikawa K, et al. Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis. Science 2008, 319: 624-627.
    • (2008) Science , vol.319 , pp. 624-627
    • Asagiri, M.1    Hirai, T.2    Kunigami, T.3    Kamano, S.4    Gober, H.J.5    Okamoto, K.6    Nishikawa, K.7
  • 55
    • 79955743119 scopus 로고    scopus 로고
    • Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase
    • Ewald SE, Engel A, Lee J, Wang M, Bogyo M and Barton GM. Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase. J Exp Med 2011, 208: 643-651.
    • (2011) J Exp Med , vol.208 , pp. 643-651
    • Ewald, S.E.1    Engel, A.2    Lee, J.3    Wang, M.4    Bogyo, M.5    Barton, G.M.6
  • 56
    • 67649232601 scopus 로고    scopus 로고
    • Identification of an N-terminal recognition site in TLR9 that contributes to CpG-DNA-mediated receptor activation
    • Peter ME, Kubarenko AV, Weber AN and Dalpke AH. Identification of an N-terminal recognition site in TLR9 that contributes to CpG-DNA-mediated receptor activation. J Immunol 2009, 182: 7690-7697.
    • (2009) J Immunol , vol.182 , pp. 7690-7697
    • Peter, M.E.1    Kubarenko, A.V.2    Weber, A.N.3    Dalpke, A.H.4
  • 57
    • 78650638271 scopus 로고    scopus 로고
    • TLR9 is actively recruited to Aspergillus fumigatus phagosomes and requires the N-terminal proteolytic cleavage domain for proper intracellular trafficking
    • Kasperkovitz PV, Cardenas ML and Vyas JM. TLR9 is actively recruited to Aspergillus fumigatus phagosomes and requires the N-terminal proteolytic cleavage domain for proper intracellular trafficking. J Immunol 2010, 185: 7614-7622.
    • (2010) J Immunol , vol.185 , pp. 7614-7622
    • Kasperkovitz, P.V.1    Cardenas, M.L.2    Vyas, J.M.3
  • 59
    • 84866558003 scopus 로고    scopus 로고
    • Proteolytic processing regulates Toll-like receptor 3 stability and endosomal localization
    • Qi R, Singh D and Kao CC. Proteolytic processing regulates Toll-like receptor 3 stability and endosomal localization. J Biol Chem 2012, 287: 32617-3229.
    • (2012) J Biol Chem , vol.287 , pp. 32617-33229
    • Qi, R.1    Singh, D.2    Kao, C.C.3
  • 60
    • 33947134377 scopus 로고    scopus 로고
    • Autophagy-dependent viral recognition by plasmacytoid dendritic cells
    • Lee HK, Lund JM, Ramanathan B, Mizushima N and Iwasaki A. Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science 2007, 315: 1398-1401.
    • (2007) Science , vol.315 , pp. 1398-1401
    • Lee, H.K.1    Lund, J.M.2    Ramanathan, B.3    Mizushima, N.4    Iwasaki, A.5
  • 62
    • 84863146376 scopus 로고    scopus 로고
    • Autophagy in innate recognition of pathogens and adaptive immunity
    • Oh JE and Lee HK. Autophagy in innate recognition of pathogens and adaptive immunity. Yonsei Med J 2012, 53: 241-247.
    • (2012) Yonsei Med J , vol.53 , pp. 241-247
    • Oh, J.E.1    Lee, H.K.2
  • 64
    • 77953601881 scopus 로고    scopus 로고
    • Regulation of innate immune responses by autophagy-related proteins
    • Saitoh T and Akira S. Regulation of innate immune responses by autophagy-related proteins. J Cell Biol 2010, 189: 925-935.
    • (2010) J Cell Biol , vol.189 , pp. 925-935
    • Saitoh, T.1    Akira, S.2
  • 66
    • 67549139899 scopus 로고    scopus 로고
    • Toll-like receptors in control of immunological autophagy
    • Delgado MA and Deretic V. Toll-like receptors in control of immunological autophagy. Cell Death Differ 2009, 16: 976-983.
    • (2009) Cell Death Differ , vol.16 , pp. 976-983
    • Delgado, M.A.1    Deretic, V.2
  • 67
  • 68
    • 36049014444 scopus 로고    scopus 로고
    • Modification of cellular autophagy protein LC3 by poliovirus
    • Taylor MP and Kirkegaard K. Modification of cellular autophagy protein LC3 by poliovirus. J Virol 2007, 81: 12543-12553.
    • (2007) J Virol , vol.81 , pp. 12543-12553
    • Taylor, M.P.1    Kirkegaard, K.2
  • 69
    • 77956525570 scopus 로고    scopus 로고
    • Coronaviruses Hijack the LC3-I-positive edemosomes, ER-derived vesicles exporting short-lived ERAD regulators, for replication
    • Reggiori F, Monastyrska I, Verheije MH, Cali T, Ulasli M, Bianchi S and Bernasconi R, et al. Coronaviruses Hijack the LC3-I-positive edemosomes, ER-derived vesicles exporting short-lived ERAD regulators, for replication. Cell Host Microbe 2010, 7: 500-508.
    • (2010) Cell Host Microbe , vol.7 , pp. 500-508
    • Reggiori, F.1    Monastyrska, I.2    Verheije, M.H.3    Cali, T.4    Ulasli, M.5    Bianchi, S.6    Bernasconi, R.7
  • 70
    • 50949133741 scopus 로고    scopus 로고
    • Autophagosome supports coxsackievirus B3 replication in host cells
    • Wong J, Zhang J, Si X, Gao G, Mao I, McManus BM and Luo H. Autophagosome supports coxsackievirus B3 replication in host cells. J Virol 2008, 82: 9143-9153.
    • (2008) J Virol , vol.82 , pp. 9143-9153
    • Wong, J.1    Zhang, J.2    Si, X.3    Gao, G.4    Mao, I.5    McManus, B.M.6    Luo, H.7
  • 71
    • 41449113692 scopus 로고    scopus 로고
    • Potential subversion of autophagosomal pathway by picornaviruses
    • Taylor MP and Kirkegaard K. Potential subversion of autophagosomal pathway by picornaviruses. Autophagy 2008, 4: 286-289.
    • (2008) Autophagy , vol.4 , pp. 286-289
    • Taylor, M.P.1    Kirkegaard, K.2
  • 72
    • 78650961487 scopus 로고    scopus 로고
    • Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro
    • Ke PY and Chen SS. Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro. J Clin Invest 2011, 121: 37-56.
    • (2011) J Clin Invest , vol.121 , pp. 37-56
    • Ke, P.Y.1    Chen, S.S.2
  • 73
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kB by Toll-like receptor 3
    • Alexopoulou L, Holt AC, Medzhitov R and Flavell RA. Recognition of double-stranded RNA and activation of NF-kB by Toll-like receptor 3. Nature 2001, 413: 732-738.
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 75
    • 11144273976 scopus 로고    scopus 로고
    • Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis
    • Wang T, Town T, Alexopoulou L, Anderson JF, Fikrig E and Flavell RA. Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nat Med 2004, 10: 1366-1373.
    • (2004) Nat Med , vol.10 , pp. 1366-1373
    • Wang, T.1    Town, T.2    Alexopoulou, L.3    Anderson, J.F.4    Fikrig, E.5    Flavell, R.A.6
  • 76
    • 79851492362 scopus 로고    scopus 로고
    • RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection
    • Nasirudeen AMA, Wong HH, Thien PL, Xu S, Lam KP and Liu DX. RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection. PLoS Negl Tropl Dis 2011, 5: e926.
    • (2011) PLoS Negl Tropl Dis , vol.5
    • Nasirudeen, A.M.A.1    Wong, H.H.2    Thien, P.L.3    Xu, S.4    Lam, K.P.5    Liu, D.X.6
  • 81
    • 58149510024 scopus 로고    scopus 로고
    • A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity
    • Negishi H, Osawa T, Ogami K, Ouyang X, Sakaguchi S, Koshiba R and Yanai H, et al. A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity. Proc Natl Acad Sci USA 2008, 105: 20446-20451.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 20446-20451
    • Negishi, H.1    Osawa, T.2    Ogami, K.3    Ouyang, X.4    Sakaguchi, S.5    Koshiba, R.6    Yanai, H.7
  • 82
    • 79953063234 scopus 로고    scopus 로고
    • TICAM-1/TRIF, a TLR3 adaptor, is essential for protection against poliovirus infection
    • Oshiumi H, Matsumoto M and Seya T. TICAM-1/TRIF, a TLR3 adaptor, is essential for protection against poliovirus infection. Int Immunol 2010, 22: i19.
    • (2010) Int Immunol , vol.22
    • Oshiumi, H.1    Matsumoto, M.2    Seya, T.3
  • 84
    • 70350488070 scopus 로고    scopus 로고
    • Epstein-Barrvirus (EBV)- encoded small RNA is released from EBV-infected cells and activates signaling from Toll-like receptor 3
    • Iwakiri D, Zhou L, Samanta M, Matsumoto M, Ebihara T, Seya T and Imai S, et al. Epstein-Barrvirus (EBV)- encoded small RNA is released from EBV-infected cells and activates signaling from Toll-like receptor 3. J Exp Med 2009, 206: 2091-2099.
    • (2009) J Exp Med , vol.206 , pp. 2091-2099
    • Iwakiri, D.1    Zhou, L.2    Samanta, M.3    Matsumoto, M.4    Ebihara, T.5    Seya, T.6    Imai, S.7
  • 85
    • 84863393834 scopus 로고    scopus 로고
    • Activation of chemokine and inflammatory cytokine response in hepatitis C virus-infected hepatocytes depends on Toll-like receptor 3 sensing of hepatitis C virus double-stranded RNA intermediates
    • Li K, Li NL, Wei D, Pfeffer SR, Fan M and Pfeffer LM. Activation of chemokine and inflammatory cytokine response in hepatitis C virus-infected hepatocytes depends on Toll-like receptor 3 sensing of hepatitis C virus double-stranded RNA intermediates. Hepatology 2012, 55: 666-675.
    • (2012) Hepatology , vol.55 , pp. 666-675
    • Li, K.1    Li, N.L.2    Wei, D.3    Pfeffer, S.R.4    Fan, M.5    Pfeffer, L.M.6
  • 86
    • 43949099295 scopus 로고    scopus 로고
    • Upregulation of the TLR3 pathway by kaposi's sarcoma-associated herpesvirus during primary infection
    • West J and Damania B. Upregulation of the TLR3 pathway by kaposi's sarcoma-associated herpesvirus during primary infection. J Virol 2008, 82: 5440-5449.
    • (2008) J Virol , vol.82 , pp. 5440-5449
    • West, J.1    Damania, B.2
  • 89
    • 12144286763 scopus 로고    scopus 로고
    • Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
    • Tabeta K, Georgel P, Janssen E, Du X, Hoebe K, Crozat K and Mudd S, et al. Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc Natl Acad Sci USA 2004, 101: 3516-3522.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 3516-3522
    • Tabeta, K.1    Georgel, P.2    Janssen, E.3    Du, X.4    Hoebe, K.5    Crozat, K.6    Mudd, S.7
  • 90
    • 19944432184 scopus 로고    scopus 로고
    • Double stranded RNAs from the helminth parasite activates TLR3 in dendritic cells
    • Aksoy E, Zouain CS and Vanhoutte F. Double stranded RNAs from the helminth parasite activates TLR3 in dendritic cells. J Biol Chem 2005, 280: 277-283.
    • (2005) J Biol Chem , vol.280 , pp. 277-283
    • Aksoy, E.1    Zouain, C.S.2    Vanhoutte, F.3
  • 91
    • 84856267624 scopus 로고    scopus 로고
    • TLR3 essentially promotes protective class I-restricted memory CD8-T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients
    • Carvalho A, De Luca A, Bozza S, Cunha C, D'Angelo C, Moretti S and Perruccio K, et al. TLR3 essentially promotes protective class I-restricted memory CD8-T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients. Blood 2012, 119: 967-977.
    • (2012) Blood , vol.119 , pp. 967-977
    • Carvalho, A.1    De Luca, A.2    Bozza, S.3    Cunha, C.4    D'Angelo, C.5    Moretti, S.6    Perruccio, K.7
  • 92
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7- mediated recognition of single-stranded RNA
    • Diebold SS, Kaisho T, Hemmi H, Akira S and Reise SC. Innate antiviral responses by means of TLR7- mediated recognition of single-stranded RNA. Science 2004, 303: 1529-1531.
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Reise, S.C.5
  • 93
    • 1542317578 scopus 로고    scopus 로고
    • Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
    • Heil F, Hemmi H, Hochrein H, Ampenberger F, Kirschning C, Akira S and Akira S, et al. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 2004, 303: 1481-1482.
    • (2004) Science , vol.303 , pp. 1481-1482
    • Heil, F.1    Hemmi, H.2    Hochrein, H.3    Ampenberger, F.4    Kirschning, C.5    Akira, S.6    Akira, S.7
  • 97
    • 35548990180 scopus 로고    scopus 로고
    • Molecular cloning and functional characterization of porcine toll-like receptor 7 involved in recognition of single-stranded RNA virus/ssRNA
    • Zhang YL, Guo YJ, Sun SH, Su X, Cai K, Wang D and Chen H, et al. Molecular cloning and functional characterization of porcine toll-like receptor 7 involved in recognition of single-stranded RNA virus/ssRNA. Mol Immunol 2008, 45: 1184-1190.
    • (2008) Mol Immunol , vol.45 , pp. 1184-1190
    • Zhang, Y.L.1    Guo, Y.J.2    Sun, S.H.3    Su, X.4    Cai, K.5    Wang, D.6    Chen, H.7
  • 99
    • 33750813795 scopus 로고    scopus 로고
    • Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition
    • Wang JP, Liu P, Latz E, Golenbock DT, Finberg RW and Libraty DH. Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition. J Immunol 2006, 177: 7114-7121.
    • (2006) J Immunol , vol.177 , pp. 7114-7121
    • Wang, J.P.1    Liu, P.2    Latz, E.3    Golenbock, D.T.4    Finberg, R.W.5    Libraty, D.H.6
  • 100
    • 67349201065 scopus 로고    scopus 로고
    • Hepatitis C virus single-stranded RNA induces innate immunity via Toll-like receptor 7
    • Zhang YL, Guo YJ, Li B and Sun SH. Hepatitis C virus single-stranded RNA induces innate immunity via Toll-like receptor 7. J Hepatol 2009, 51: 29-38.
    • (2009) J Hepatol , vol.51 , pp. 29-38
    • Zhang, Y.L.1    Guo, Y.J.2    Li, B.3    Sun, S.H.4
  • 101
    • 33846886363 scopus 로고    scopus 로고
    • Control of coronavirus infection through plasmacytoid dendritic-cell-derived type i interferon
    • Cervantes-Barragan L, Zust R, Weber F, Spiegel M, Lang KS, Akira S and Thiel V, et al. Control of coronavirus infection through plasmacytoid dendritic-cell-derived type I interferon. Blood 2007, 109: 1131-1137.
    • (2007) Blood , vol.109 , pp. 1131-1137
    • Cervantes-Barragan, L.1    Zust, R.2    Weber, F.3    Spiegel, M.4    Lang, K.S.5    Akira, S.6    Thiel, V.7
  • 102
    • 79960466171 scopus 로고    scopus 로고
    • Innate immune sensing of retroviral infection via Toll-like receptor 7 occurs upon viral entry
    • Kane M, Case LK, Wang C, Yurkovetskiy L, Dikiy S and Golovkina TV. Innate immune sensing of retroviral infection via Toll-like receptor 7 occurs upon viral entry. Immunity 2011, 35: 135-145.
    • (2011) Immunity , vol.35 , pp. 135-145
    • Kane, M.1    Case, L.K.2    Wang, C.3    Yurkovetskiy, L.4    Dikiy, S.5    Golovkina, T.V.6
  • 103
    • 79956212220 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells promote host defense against acute pneumovirus infection via the TLR7-MyD88-dependent signaling pathway
    • Davidson S, Kaiko G, Loh Z, Lalwani A, Zhang V, Spann K and Foo SY, et al. Plasmacytoid dendritic cells promote host defense against acute pneumovirus infection via the TLR7-MyD88-dependent signaling pathway. J Immunol 2011, 186: 5938-5948.
    • (2011) J Immunol , vol.186 , pp. 5938-5948
    • Davidson, S.1    Kaiko, G.2    Loh, Z.3    Lalwani, A.4    Zhang, V.5    Spann, K.6    Foo, S.Y.7
  • 105
    • 79952750092 scopus 로고    scopus 로고
    • Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-beta
    • Cervantes JL, Dunham-Ems SM, La Vake CJ, Petzke MM, Sahay B, Sellati TJ and Radolf JD, et al. Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-beta. Proc Natl Acad Sci USA 2011, 108: 3683-3688.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 3683-3688
    • Cervantes, J.L.1    Dunham-Ems, S.M.2    La Vake, C.J.3    Petzke, M.M.4    Sahay, B.5    Sellati, T.J.6    Radolf, J.D.7
  • 107
    • 80051937446 scopus 로고    scopus 로고
    • Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi
    • Caetano BC, Carmo BB, Melo MB, Cerny A, dos Santos SL, Bartholomeu DC and Golenbock DT, et al. Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi. J Immunol 2011, 187: 1903-1911.
    • (2011) J Immunol , vol.187 , pp. 1903-1911
    • Caetano, B.C.1    Carmo, B.B.2    Melo, M.B.3    Cerny, A.4    Dos Santos, S.L.5    Bartholomeu, D.C.6    Golenbock, D.T.7
  • 108
    • 79952774989 scopus 로고    scopus 로고
    • Conventional dendritic cells mount a type i IFN response against Candida spp. requiring novel phagosomal TLR7-mediated IFN-beta signaling
    • Bourgeois C, Majer O, Frohner IE, Lesiak-Markowicz I, Hildering KS, Glaser W and Stockinger S, et al. Conventional dendritic cells mount a type I IFN response against Candida spp. requiring novel phagosomal TLR7-mediated IFN-beta signaling. J Immunol 2011, 186: 3104-3112.
    • (2011) J Immunol , vol.186 , pp. 3104-3112
    • Bourgeois, C.1    Majer, O.2    Frohner, I.E.3    Lesiak-Markowicz, I.4    Hildering, K.S.5    Glaser, W.6    Stockinger, S.7
  • 109
  • 110
    • 3843103508 scopus 로고    scopus 로고
    • Herpes simplex virus type-1 induces IFN-αlpha production via Toll-like receptor 9-dependent and-independent pathways
    • Hochrein H, Schlatter B, O'Keeffe M, Wagner C, Schmitz F, Schiemann M and Bauer S, et al. Herpes simplex virus type-1 induces IFN-αlpha production via Toll-like receptor 9-dependent and-independent pathways. Proc Natl Acad Sci USA 2004, 101: 11416-11421.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11416-11421
    • Hochrein, H.1    Schlatter, B.2    O'Keeffe, M.3    Wagner, C.4    Schmitz, F.5    Schiemann, M.6    Bauer, S.7
  • 111
    • 0042123694 scopus 로고    scopus 로고
    • Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells
    • Lund J, Sato A, Akira S, Medzhitov R and Iwasaki A. Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells. J Exp Med 2003, 198: 513-520.
    • (2003) J Exp Med , vol.198 , pp. 513-520
    • Lund, J.1    Sato, A.2    Akira, S.3    Medzhitov, R.4    Iwasaki, A.5
  • 112
    • 27744451943 scopus 로고    scopus 로고
    • MyD88-dependent and-independent murine cytomegalovirus sensing for IFN-αlpha release and initiation of immune responses in vivo
    • Delale T, Paquin A, Asselin-Paturel C, Dalod M, Brizard G, Bates EE and Kastner P, et al. MyD88-dependent and-independent murine cytomegalovirus sensing for IFN-αlpha release and initiation of immune responses in vivo. J Immunol 2005, 175: 672367-32.
    • (2005) J Immunol , vol.175 , pp. 672367-672342
    • Delale, T.1    Paquin, A.2    Asselin-Paturel, C.3    Dalod, M.4    Brizard, G.5    Bates, E.E.6    Kastner, P.7
  • 113
    • 33947396347 scopus 로고    scopus 로고
    • Innate immune response to adenoviral vectors is mediated by both Toll-like receptor-dependent and-independent pathways
    • Zhu J, Huang X and Yang Y. Innate immune response to adenoviral vectors is mediated by both Toll-like receptor-dependent and-independent pathways. J Virol 2007, 81: 3170-3180.
    • (2007) J Virol , vol.81 , pp. 3170-3180
    • Zhu, J.1    Huang, X.2    Yang, Y.3
  • 114
    • 13944263526 scopus 로고    scopus 로고
    • Involvement of the Toll-like receptor 9 signaling pathway in the induction of innate immunity by baculovirus
    • Abe T, Hemmi H, Miyamoto H, Moriishi K, Tamura S, Takaku H and Akira S, et al. Involvement of the Toll-like receptor 9 signaling pathway in the induction of innate immunity by baculovirus. J Virol 2005, 79: 2847-2858.
    • (2005) J Virol , vol.79 , pp. 2847-2858
    • Abe, T.1    Hemmi, H.2    Miyamoto, H.3    Moriishi, K.4    Tamura, S.5    Takaku, H.6    Akira, S.7
  • 115
    • 84859221717 scopus 로고    scopus 로고
    • Understanding TLR9 action in Epstein-Barr virus infection
    • Zauner L and Nadal D. Understanding TLR9 action in Epstein-Barr virus infection. Front Biosci 2012, 17: 1219-1231.
    • (2012) Front Biosci , vol.17 , pp. 1219-1231
    • Zauner, L.1    Nadal, D.2
  • 116
    • 84862019026 scopus 로고    scopus 로고
    • HHV-6B induces IFN-lambda1 responses in cord plasmacytoid dendritic cells through TLR9
    • Nordström I and Eriksson K. HHV-6B induces IFN-lambda1 responses in cord plasmacytoid dendritic cells through TLR9. PLoS one 2012, 7: e38683.
    • (2012) PLoS One , vol.7
    • Nordström, I.1    Eriksson, K.2
  • 117
    • 79952370187 scopus 로고    scopus 로고
    • IFN-α production by human mononuclear cells infected with varicella-zoster virus through TLR9-dependent and -independent pathways
    • Yu HR, Huang HC, Kuo HC, Sheen JM, Ou CY, Hsu TY and Yang KD. IFN-α production by human mononuclear cells infected with varicella-zoster virus through TLR9-dependent and -independent pathways. Cell Mol Immunol 2011, 8: 181-188.
    • (2011) Cell Mol Immunol , vol.8 , pp. 181-188
    • Yu, H.R.1    Huang, H.C.2    Kuo, H.C.3    Sheen, J.M.4    Ou, C.Y.5    Hsu, T.Y.6    Yang, K.D.7
  • 118
    • 40449107086 scopus 로고    scopus 로고
    • TLR9 contributes to antiviral immunity during gammaherpesvirus infection
    • Guggemoos S, Hangel D, Hamm S, Heit A, Bauer S and Adler H. TLR9 contributes to antiviral immunity during gammaherpesvirus infection. J Immunol 2008, 180: 438-443.
    • (2008) J Immunol , vol.180 , pp. 438-443
    • Guggemoos, S.1    Hangel, D.2    Hamm, S.3    Heit, A.4    Bauer, S.5    Adler, H.6
  • 119
    • 43049088102 scopus 로고    scopus 로고
    • Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection
    • Samuelsson C, Hausmann J, Lauterbach H, Schmidt M, Akira S, Wagner H and Chaplin P, et al. Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection. J Clin Invest 2008, 118: 1776-1784.
    • (2008) J Clin Invest , vol.118 , pp. 1776-1784
    • Samuelsson, C.1    Hausmann, J.2    Lauterbach, H.3    Schmidt, M.4    Akira, S.5    Wagner, H.6    Chaplin, P.7
  • 121
    • 84866313009 scopus 로고    scopus 로고
    • Immune receptors involved in Streptococcus suis recognition by dendritic cells
    • Lecours MP, Segura M, Fittipaldi N, Rivest S and Gottschalk M. Immune receptors involved in Streptococcus suis recognition by dendritic cells. PLoS One 2012, 7: e44746.
    • (2012) PLoS One , vol.7
    • Lecours, M.P.1    Segura, M.2    Fittipaldi, N.3    Rivest, S.4    Gottschalk, M.5
  • 122
    • 79952220311 scopus 로고    scopus 로고
    • Innate immune effectors in mycobacterial infection
    • Saiga H, Shimada Y and Takeda K. Innate immune effectors in mycobacterial infection. Clin Dev Immunol 2011, 2011: 347594.
    • (2011) Clin Dev Immunol , vol.2011 , pp. 347594
    • Saiga, H.1    Shimada, Y.2    Takeda, K.3
  • 125
    • 84864046130 scopus 로고    scopus 로고
    • DNase Sda1 allows invasive M1T1 group A Streptococcus to prevent TLR9-dependent recognition
    • Uchiyama S, Andreoni F, Schuepbach RA, Nizet V and Zinkernagel AS. DNase Sda1 allows invasive M1T1 group A Streptococcus to prevent TLR9-dependent recognition. PLoS Pathog 2012, 8: e1002736.
    • (2012) PLoS Pathog , vol.8
    • Uchiyama, S.1    Andreoni, F.2    Schuepbach, R.A.3    Nizet, V.4    Zinkernagel, A.S.5
  • 126
    • 84867317920 scopus 로고    scopus 로고
    • Staphylococcus aureus induces type i IFN signaling in dendritic cells via TLR9
    • Parker D and Prince A. Staphylococcus aureus induces type I IFN signaling in dendritic cells via TLR9. J Immunol 2012, 189: 4040-4046.
    • (2012) J Immunol , vol.189 , pp. 4040-4046
    • Parker, D.1    Prince, A.2
  • 127
    • 33748477504 scopus 로고    scopus 로고
    • Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection
    • Bafica A, Santiago HC, Goldszmid R, Ropert C, Gazzinelli RT and Sher A. Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection. J Immunol 2006, 177: 3515-3519.
    • (2006) J Immunol , vol.177 , pp. 3515-3519
    • Bafica, A.1    Santiago, H.C.2    Goldszmid, R.3    Ropert, C.4    Gazzinelli, R.T.5    Sher, A.6
  • 129
    • 63149173273 scopus 로고    scopus 로고
    • TLR9-dependent activation of dendritic cells by DNA from Leishmania major favors Th1 cell development and the resolution of lesions
    • Abou Fakher FH, Rachinel N, Klimczak M, Louis J and Doyen N. TLR9-dependent activation of dendritic cells by DNA from Leishmania major favors Th1 cell development and the resolution of lesions. J Immunol 2009, 182: 1386-1396.
    • (2009) J Immunol , vol.182 , pp. 1386-1396
    • Abou Fakher, F.H.1    Rachinel, N.2    Klimczak, M.3    Louis, J.4    Doyen, N.5
  • 130
    • 74049121298 scopus 로고    scopus 로고
    • Immunogenicity of whole parasite vaccines against plasmodium falciparum involves malarial hemozoin and host TLR9
    • Coban C, Igari Y, Yagi M, Reimer T, Koyama S, Aoshi T and Ohata K, et al. Immunogenicity of whole parasite vaccines against plasmodium falciparum involves malarial hemozoin and host TLR9. Cell Host Microbe 2010, 7: 50-61.
    • (2010) Cell Host Microbe , vol.7 , pp. 50-61
    • Coban, C.1    Igari, Y.2    Yagi, M.3    Reimer, T.4    Koyama, S.5    Aoshi, T.6    Ohata, K.7
  • 131
    • 33846911691 scopus 로고    scopus 로고
    • Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9
    • Parroche P, Lauw FN, Goutagny N, Latz E, Monks BG, Visintin A and Halmen KA, et al. Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9. Proc Natl Acad Sci USA 2007, 104: 1919-1924.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 1919-1924
    • Parroche, P.1    Lauw, F.N.2    Goutagny, N.3    Latz, E.4    Monks, B.G.5    Visintin, A.6    Halmen, K.A.7
  • 133
    • 84855754509 scopus 로고    scopus 로고
    • Toll-like receptor 9 modulates macrophage antifungal effector function during innate recognition of candida albicans and saccharomyces cerevisiae
    • Kasperkovitz PV, Khan NS, Tam JM, Mansour MK, Davids PJ and Vyas JM. Toll-like receptor 9 modulates macrophage antifungal effector function during innate recognition of candida albicans and saccharomyces cerevisiae. Infect Immun 2011, 79: 4858-4867.
    • (2011) Infect Immun , vol.79 , pp. 4858-4867
    • Kasperkovitz, P.V.1    Khan, N.S.2    Tam, J.M.3    Mansour, M.K.4    Davids, P.J.5    Vyas, J.M.6
  • 134
    • 84866426515 scopus 로고    scopus 로고
    • Innate immunity: TLR13, unlucky, but just for some
    • Bordon Y. Innate immunity: TLR13, unlucky, but just for some. Nat Rev Immunol 2012, 12: 618-619.
    • (2012) Nat Rev Immunol , vol.12 , pp. 618-619
    • Bordon, Y.1
  • 137
    • 80053922801 scopus 로고    scopus 로고
    • Viral double-strand RNA-binding proteins can enhance innate immune signaling by Toll-like receptor 3
    • Lai Y, Yi G, Chen A, Bhardwaj K, Tragesser BJ, Rodrigo AValverde and Zlotnick A, et al. Viral double-strand RNA-binding proteins can enhance innate immune signaling by Toll-like receptor 3. PLoS One 2011, 6: e25837.
    • (2011) PLoS One , vol.6
    • Lai, Y.1    Yi, G.2    Chen, A.3    Bhardwaj, K.4    Tragesser, B.J.5    Avalverde, R.6    Zlotnick, A.7
  • 139
    • 74449089424 scopus 로고    scopus 로고
    • A five-amino-acid motif in the undefined region of the TLR8 ectodomain is required for species-specific ligand recognition
    • Liu J, Xu C, Hsu LC, Luo Y, Xiang R and Chuang TH. A five-amino-acid motif in the undefined region of the TLR8 ectodomain is required for species-specific ligand recognition. Mol Immunol 2010, 47: 1083-1090.
    • (2010) Mol Immunol , vol.47 , pp. 1083-1090
    • Liu, J.1    Xu, C.2    Hsu, L.C.3    Luo, Y.4    Xiang, R.5    Chuang, T.H.6
  • 140
    • 80052938022 scopus 로고    scopus 로고
    • Comparative analysis of species-specific ligand recognition in Toll-like receptor 8 signaling: A hypothesis
    • Govindaraj RG, Manavalan B, Basith S and Choi S. Comparative analysis of species-specific ligand recognition in Toll-like receptor 8 signaling: a hypothesis. PLoS One 2011, 6: e25118.
    • (2011) PLoS One , vol.6
    • Govindaraj, R.G.1    Manavalan, B.2    Basith, S.3    Choi, S.4
  • 141
    • 33750823681 scopus 로고    scopus 로고
    • Cutting edge: Activation of murine TLR8 by a combination of imidazoquinoline immune response modifiers and polyoligodeoxynucleotides
    • Gorden KK, Qiu XX, Binsfeld CC, Vasilakos JP and Alkan SS. Cutting edge: activation of murine TLR8 by a combination of imidazoquinoline immune response modifiers and polyoligodeoxynucleotides. J Immunol 2006, 177: 6584-6587.
    • (2006) J Immunol , vol.177 , pp. 6584-6587
    • Gorden, K.K.1    Qiu, X.X.2    Binsfeld, C.C.3    Vasilakos, J.P.4    Alkan, S.S.5
  • 143
    • 44649137559 scopus 로고    scopus 로고
    • Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses
    • Forsbach A, Nemorin JG, Montino C, Müller C, Samulowitz U, Vicari AP and Jurk M, et al. Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses. J Immunol 2008, 180: 3729-3738.
    • (2008) J Immunol , vol.180 , pp. 3729-3738
    • Forsbach, A.1    Nemorin, J.G.2    Montino, C.3    Müller, C.4    Samulowitz, U.5    Vicari, A.P.6    Jurk, M.7
  • 144
    • 84861325064 scopus 로고    scopus 로고
    • The double-stranded RNA bluetongue virus induces type i interferon in plasmacytoid dendritic cells via a MYD88-dependent TLR7/8-independent signaling pathway
    • Ruscanu S, Pascale F, Bourge M, Hemati B, Elhmouzi-Younes J, Urien C and Bonneau M, et al. The double-stranded RNA bluetongue virus induces type I interferon in plasmacytoid dendritic cells via a MYD88-dependent TLR7/8-independent signaling pathway. J Virol 2012, 86: 5817-5828.
    • (2012) J Virol , vol.86 , pp. 5817-5828
    • Ruscanu, S.1    Pascale, F.2    Bourge, M.3    Hemati, B.4    Elhmouzi-Younes, J.5    Urien, C.6    Bonneau, M.7
  • 145
    • 23844464444 scopus 로고    scopus 로고
    • Suppression of RNA recognition by Toll-like receptors: The impact of nucleoside modification and the evolutionary origin of RNA
    • Karikó K, Buckstein M, Ni H and Weissman D. Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA. Immunity 2005, 23: 165-175.
    • (2005) Immunity , vol.23 , pp. 165-175
    • Karikó, K.1    Buckstein, M.2    Ni, H.3    Weissman, D.4
  • 146
    • 26844467349 scopus 로고    scopus 로고
    • Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus
    • Barrat FJ, Meeker T, Gregorio J, Barrat FJ, Meeker T, Gregorio J and Chan JH, et al. Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus. J Exp Med 2005, 202: 1131-1139.
    • (2005) J Exp Med , vol.202 , pp. 1131-1139
    • Barrat, F.J.1    Meeker, T.2    Gregorio, J.3    Barrat, F.J.4    Meeker, T.5    Gregorio, J.6    Chan, J.H.7
  • 148
    • 77957020717 scopus 로고    scopus 로고
    • Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors
    • Cros J, Cagnard N, Woollard K, Patey N, Zhang SY, Senechal B and Puel A, et al. Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors. Immunity 2010, 33: 375-386.
    • (2010) Immunity , vol.33 , pp. 375-386
    • Cros, J.1    Cagnard, N.2    Woollard, K.3    Patey, N.4    Zhang, S.Y.5    Senechal, B.6    Puel, A.7
  • 149
    • 20144389695 scopus 로고    scopus 로고
    • Sequence-specific potent induction of IFN-αlpha by short interfering RNA in plasmacytoid dendritic cells through TLR7
    • Hornung V, Guenthner-Biller M, Bourquin C, Ablasser A, Schlee M, Uematsu S and Noronha A, et al. Sequence-specific potent induction of IFN-αlpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med 2005, 11: 263-270.
    • (2005) Nat Med , vol.11 , pp. 263-270
    • Hornung, V.1    Guenthner-Biller, M.2    Bourquin, C.3    Ablasser, A.4    Schlee, M.5    Uematsu, S.6    Noronha, A.7
  • 150
    • 84866773569 scopus 로고    scopus 로고
    • Structure-dependent immunostimulatory effect of CpG oligodeoxynucleotides and their delivery system
    • Hanagata N. Structure-dependent immunostimulatory effect of CpG oligodeoxynucleotides and their delivery system. Int J Nanomed 2012, 7: 2181-2195.
    • (2012) Int J Nanomed , vol.7 , pp. 2181-2195
    • Hanagata, N.1
  • 151
    • 84861728909 scopus 로고    scopus 로고
    • Essential role for IKKb in production of type i interferons by plasmacytoid dendritic cells
    • Pauls E, Shpiro N, Peggie M, Young ER, Sorcek RJ, Tan L and Choi HG, et al. Essential role for IKKb in production of type I interferons by plasmacytoid dendritic cells. J Biol Chem 2012, 287: 19216-1928.
    • (2012) J Biol Chem , vol.287 , pp. 19216-11938
    • Pauls, E.1    Shpiro, N.2    Peggie, M.3    Young, E.R.4    Sorcek, R.J.5    Tan, L.6    Choi, H.G.7
  • 153
    • 67650744586 scopus 로고    scopus 로고
    • The role of ubiquitin in NF-kappaB regulatory pathways
    • Skaug B, Jiang X and Chen ZJ. The role of ubiquitin in NF-kappaB regulatory pathways. Annu Rev Biochem 2009, 78: 769-796.
    • (2009) Annu Rev Biochem , vol.78 , pp. 769-796
    • Skaug, B.1    Jiang, X.2    Chen, Z.J.3
  • 154
    • 52549127241 scopus 로고    scopus 로고
    • Toll-like receptor-mediated induction of type i interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI3KmTOR- p70S6K pathway
    • Cao W, Manicassamy S, Tang H, Kasturi SP, Pirani A, Murthy N and Pulendran B. Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI3KmTOR- p70S6K pathway. Nat Immunol 2008, 9: 1157-1164.
    • (2008) Nat Immunol , vol.9 , pp. 1157-1164
    • Cao, W.1    Manicassamy, S.2    Tang, H.3    Kasturi, S.P.4    Pirani, A.5    Murthy, N.6    Pulendran, B.7
  • 155
    • 2442689141 scopus 로고    scopus 로고
    • Toll-like receptor 9 signaling activates NF-kB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells
    • Tsujimura H, Tamura T, Kong HJ, Nishiyama A, Ishii KJ, Klinman DM and Ozato K. Toll-like receptor 9 signaling activates NF-kB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells. J Immunol 2004, 172: 6820-7682.
    • (2004) J Immunol , vol.172 , pp. 6820-7682
    • Tsujimura, H.1    Tamura, T.2    Kong, H.J.3    Nishiyama, A.4    Ishii, K.J.5    Klinman, D.M.6    Ozato, K.7
  • 156
    • 84865298775 scopus 로고    scopus 로고
    • Dissecting negative regulation of Toll-like receptor signaling
    • Kondo T, Kawai T and Akira S. Dissecting negative regulation of Toll-like receptor signaling. Trends Immunol 2012, 33: 449-458.
    • (2012) Trends Immunol , vol.33 , pp. 449-458
    • Kondo, T.1    Kawai, T.2    Akira, S.3
  • 157
    • 70350004240 scopus 로고    scopus 로고
    • Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3
    • Zeng W, Xu M, Liu S, Sun L and Chen ZL. Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3. Mol Cell 2009, 36: 315-25.
    • (2009) Mol Cell , vol.36 , pp. 315-325
    • Zeng, W.1    Xu, M.2    Liu, S.3    Sun, L.4    Chen, Z.L.5
  • 158
    • 79958042278 scopus 로고    scopus 로고
    • Mitochondrial ubiquitin ligase MARCH5 promotes TLR7 signaling by attenuating TANK action
    • Shi HX, Liu X, Wang Q, Tang PP, Liu XY, Shan YF and Wang C. Mitochondrial ubiquitin ligase MARCH5 promotes TLR7 signaling by attenuating TANK action. PLoS Pathog 2011, 7: e1002057.
    • (2011) PLoS Pathog , vol.7
    • Shi, H.X.1    Liu, X.2    Wang, Q.3    Tang, P.P.4    Liu, X.Y.5    Shan, Y.F.6    Wang, C.7
  • 159
    • 79952762131 scopus 로고    scopus 로고
    • Antiviral protein viperin promotes Toll-like receptor 7- and Toll-like receptor 9-mediated type i interferon production in plasmacytoid dendritic cells
    • Saitoh T, Satoh T, Yamamoto N, Uematsu S, Takeuchi O, Kawai T and Akira S. Antiviral protein viperin promotes Toll-like receptor 7- and Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells. Immunity 2011, 34: 352-363.
    • (2011) Immunity , vol.34 , pp. 352-363
    • Saitoh, T.1    Satoh, T.2    Yamamoto, N.3    Uematsu, S.4    Takeuchi, O.5    Kawai, T.6    Akira, S.7
  • 160
    • 79551574982 scopus 로고    scopus 로고
    • Inducible SUMO modification of TANK alleviates its repression of TLR7 signaling
    • Renner F, Saul VV, Pagenstecher A, Wittwer T and Schmitz ML. Inducible SUMO modification of TANK alleviates its repression of TLR7 signaling. EMBO Rep 2011, 12: 129-135.
    • (2011) EMBO Rep , vol.12 , pp. 129-135
    • Renner, F.1    Saul, V.V.2    Pagenstecher, A.3    Wittwer, T.4    Schmitz, M.L.5
  • 161
    • 67649229630 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase nrdp1 'preferentially' promotes TLR-mediated production of type i interferon
    • Wang C, Chen T, Zhang J, Yang M, Li N, Xu X and Cao XT. The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon. Nat Immunol 2009, 10: 744-752.
    • (2009) Nat Immunol , vol.10 , pp. 744-752
    • Wang, C.1    Chen, T.2    Zhang, J.3    Yang, M.4    Li, N.5    Xu, X.6    Cao, X.T.7
  • 162
    • 80052446462 scopus 로고    scopus 로고
    • MicroRNA in TLR signaling and endotoxin tolerance
    • Nahid MA, Satoh M and Chan EK. MicroRNA in TLR signaling and endotoxin tolerance. Cell Mol Immunol 2011, 8: 388-403.
    • (2011) Cell Mol Immunol , vol.8 , pp. 388-403
    • Nahid, M.A.1    Satoh, M.2    Chan, E.K.3
  • 163
    • 84862530798 scopus 로고    scopus 로고
    • Signature miRNAs involved in the innate immunity of invertebrates
    • Yang G, Yang L, Zhao Z, Wang JJ and Zhang XB. Signature miRNAs involved in the innate immunity of invertebrates. PLoS One 2012, 7: e39015.
    • (2012) PLoS One , vol.7
    • Yang, G.1    Yang, L.2    Zhao, Z.3    Wang, J.J.4    Zhang, X.B.5
  • 165
    • 2442643942 scopus 로고    scopus 로고
    • Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors
    • Chuang TH and Ulevitch RJ. Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors. Nat Immunol 2004, 5: 495-502.
    • (2004) Nat Immunol , vol.5 , pp. 495-502
    • Chuang, T.H.1    Ulevitch, R.J.2
  • 166
    • 40949163764 scopus 로고    scopus 로고
    • TRIM30 alpha negatively regulates TLR-mediated NF-kappaB activation by targeting TAB2 and TAB3 for degradation
    • Shi M, Deng W, Bi E, Mao K, Ji Y, Lin G and Wu X, et al. TRIM30 alpha negatively regulates TLR-mediated NF-kappaB activation by targeting TAB2 and TAB3 for degradation. Nat Immunol 2008, 9: 369-377.
    • (2008) Nat Immunol , vol.9 , pp. 369-377
    • Shi, M.1    Deng, W.2    Bi, E.3    Mao, K.4    Ji, Y.5    Lin, G.6    Wu, X.7
  • 168
    • 77649225756 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes
    • Shembade N, Ma A and Harhaj EW. Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes. Science 2010, 327: 1135-1139.
    • (2010) Science , vol.327 , pp. 1135-1139
    • Shembade, N.1    Ma, A.2    Harhaj, E.W.3
  • 172
    • 77951168849 scopus 로고    scopus 로고
    • Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6
    • Li S, Zheng H, Mao AP, Zhong B, Li Y, Liu Y and Gao Y, et al. Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6. J Biol Chem 2010, 285: 4291-4297.
    • (2010) J Biol Chem , vol.285 , pp. 4291-4297
    • Li, S.1    Zheng, H.2    Mao, A.P.3    Zhong, B.4    Li, Y.5    Liu, Y.6    Gao, Y.7
  • 173
    • 69049086481 scopus 로고    scopus 로고
    • TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis
    • Kawagoe T, Takeuchi O, Takabatake Y, Kato H, Isaka Y, Tsujimura T and Akira S. TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis. Nat Immunol 2009, 10: 965-972.
    • (2009) Nat Immunol , vol.10 , pp. 965-972
    • Kawagoe, T.1    Takeuchi, O.2    Takabatake, Y.3    Kato, H.4    Isaka, Y.5    Tsujimura, T.6    Akira, S.7
  • 174
    • 56249135538 scopus 로고    scopus 로고
    • A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
    • Cadwell K, Liu JY, Brown SL, Miyoshi H, Loh J, Lennerz JK and Kishi C, et al. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature 2008, 456: 259-263.
    • (2008) Nature , vol.456 , pp. 259-263
    • Cadwell, K.1    Liu, J.Y.2    Brown, S.L.3    Miyoshi, H.4    Loh, J.5    Lennerz, J.K.6    Kishi, C.7
  • 175
    • 33845438110 scopus 로고    scopus 로고
    • SHP-2 phosphatase negatively regulates the TRIF adaptor proteindependent type i interferon and proinflammatory cytokine production
    • An H, Zhao W, Hou J, Zhang Y, Xie Y, Zheng YJ and Xu HM, et al. SHP-2 phosphatase negatively regulates the TRIF adaptor proteindependent type I interferon and proinflammatory cytokine production. Immunity 2006, 25: 919-928.
    • (2006) Immunity , vol.25 , pp. 919-928
    • An, H.1    Zhao, W.2    Hou, J.3    Zhang, Y.4    Xie, Y.5    Zheng, Y.J.6    Xu, H.M.7
  • 177
    • 84863616381 scopus 로고    scopus 로고
    • CD2AP/SHIP1 complex positively regulates plasmacytoid dendritic cell receptor signaling by inhibiting the E3 ubiquitin ligase Cbl
    • Bao M, Hanabuchi S, Facchinetti V, Du Q, Bover L, Plumas J and Chaperot L, et al. CD2AP/SHIP1 complex positively regulates plasmacytoid dendritic cell receptor signaling by inhibiting the E3 ubiquitin ligase Cbl. J Immunol 2012, 189: 786-792.
    • (2012) J Immunol , vol.189 , pp. 786-792
    • Bao, M.1    Hanabuchi, S.2    Facchinetti, V.3    Du, Q.4    Bover, L.5    Plumas, J.6    Chaperot, L.7
  • 178
    • 79960657903 scopus 로고    scopus 로고
    • Negative regulation of signaling by a soluble form of toll-like receptor 9
    • Chockalingam A, Cameron JL, Brooks JC and Leifer CA. Negative regulation of signaling by a soluble form of toll-like receptor 9. Eur J Immunol 2011, 41: 2176-2184.
    • (2011) Eur J Immunol , vol.41 , pp. 2176-2184
    • Chockalingam, A.1    Cameron, J.L.2    Brooks, J.C.3    Leifer, C.A.4
  • 179
    • 33748871187 scopus 로고    scopus 로고
    • The human adaptor SARM negatively regulates adaptor protein TRIF-dependent toll-like receptor signaling
    • Carty M, Goodbody R, Schröder M, Stack J, Moynagh PN and Bowie AG. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent toll-like receptor signaling. Nat Immunol 2006, 7: 1074-1081.
    • (2006) Nat Immunol , vol.7 , pp. 1074-1081
    • Carty, M.1    Goodbody, R.2    Schröder, M.3    Stack, J.4    Moynagh, P.N.5    Bowie, A.G.6
  • 180
    • 0036006290 scopus 로고    scopus 로고
    • Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88
    • Janssens S, Burns K, Tschopp J and Beyaert R. Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88. Curr Biol 2002, 12: 467-471.
    • (2002) Curr Biol , vol.12 , pp. 467-471
    • Janssens, S.1    Burns, K.2    Tschopp, J.3    Beyaert, R.4
  • 182
    • 0037454946 scopus 로고    scopus 로고
    • Inhibition of interleukin 1 receptor/toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4
    • Burns K, Janssens S, Brissoni B, Olivos N, Beyaert R and Tschopp J. Inhibition of interleukin 1 receptor/toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J Exp Med 2003, 197: 263-268.
    • (2003) J Exp Med , vol.197 , pp. 263-268
    • Burns, K.1    Janssens, S.2    Brissoni, B.3    Olivos, N.4    Beyaert, R.5    Tschopp, J.6
  • 183
    • 79952186298 scopus 로고    scopus 로고
    • MicroRNAs: The fine-tuners of Toll-like receptor signaling
    • O'Neill LA, Sheedy FJ and McCoy CE. MicroRNAs: the fine-tuners of Toll-like receptor signaling. Nat Revs Immunol 2011, 11: 163-175.
    • (2011) Nat Revs Immunol , vol.11 , pp. 163-175
    • O'Neill, L.A.1    Sheedy, F.J.2    McCoy, C.E.3
  • 185
    • 79952789527 scopus 로고    scopus 로고
    • UNC93B1 is essential for TLR11 activation and IL-12- dependent host resistance to Toxoplasma gondii
    • Pifer R, Benson A, Sturge CR and Yarovinsky F. UNC93B1 is essential for TLR11 activation and IL-12- dependent host resistance to Toxoplasma gondii. J Biol Chem 2011, 286: 3307-3314.
    • (2011) J Biol Chem , vol.286 , pp. 3307-3314
    • Pifer, R.1    Benson, A.2    Sturge, C.R.3    Yarovinsky, F.4
  • 186
    • 77954557986 scopus 로고    scopus 로고
    • The battle between virus and host: Modulation of Toll-like receptor signaling pathways by virus infection
    • Yokota SI, Okabayashi T and Fujii N. The battle between virus and host: modulation of Toll-like receptor signaling pathways by virus infection. Mediators Inflamm 2010, 2010: 184328.
    • (2010) Mediators Inflamm , vol.2010 , pp. 184328
    • Yokota, S.I.1    Okabayashi, T.2    Fujii, N.3
  • 187
    • 77957938117 scopus 로고    scopus 로고
    • Viruses, microRNAs, and host interactions
    • Skalsky RL and Cullen BR. Viruses, microRNAs, and host interactions. Annu Rev Microbiol 2010, 64: 123-141.
    • (2010) Annu Rev Microbiol , vol.64 , pp. 123-141
    • Skalsky, R.L.1    Cullen, B.R.2
  • 188
    • 84866735326 scopus 로고    scopus 로고
    • TLR7 and TLR9 in SLE: When sensing self goes wrong
    • Celhar T, Magalhäes R and Fairhurst AM. TLR7 and TLR9 in SLE: when sensing self goes wrong. Immunol Res 2012, 53: 58-77.
    • (2012) Immunol Res , vol.53 , pp. 58-77
    • Celhar, T.1    Magalhäes, R.2    Fairhurst, A.M.3
  • 189
    • 70449092388 scopus 로고    scopus 로고
    • HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses
    • Yanai H, Ban T, Wang Z, Choi MK, Kawamura T, Negishi H and Nakasato M, et al. HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses. Nature 2009, 462: 99-103.
    • (2009) Nature , vol.462 , pp. 99-103
    • Yanai, H.1    Ban, T.2    Wang, Z.3    Choi, M.K.4    Kawamura, T.5    Negishi, H.6    Nakasato, M.7
  • 190
    • 35748964708 scopus 로고    scopus 로고
    • Toll-like receptors 7, 8, and 9 linking innate immunity to autoimmunity
    • Krieg A and Vollmer J. Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity. Immunol Rev 2007, 220: 251-269.
    • (2007) Immunol Rev. , vol.220 , pp. 251-269
    • Krieg, A.1    Vollmer, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.