Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi

Journal of Immunology

Volumn 187, Issue 4, 2011, Pages 1903-1911

  Caetano, Braulia C ^a   Carmo, Bianca B ^a   Melo, Mariane B ^a   Cerny, Anna ^a   Dos Santos, Sara L ^b   Bartholomeu, Daniella C ^b   Golenbock, Douglas T ^a,c   Gazzinelli, Ricardo T ^a,b,c  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^c INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; GAMMA INTERFERON; INTERLEUKIN 12P40; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN UNC93B1; PROTOZOAL RNA; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHAGAS DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DISEASE PREDISPOSITION; HOST RESISTANCE; IMMUNE RESPONSE; INNATE IMMUNITY; MORTALITY; MOUSE; MULTICENTER STUDY; NONHUMAN; PARASITEMIA; PRIORITY JOURNAL; PROTEIN FUNCTION; T LYMPHOCYTE; TRYPANOSOMA CRUZI;

ANIMALS; CHAGAS DISEASE; IMMUNITY, INNATE; INTERFERON-GAMMA; INTERLEUKIN-12 SUBUNIT P40; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; PARASITEMIA; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 9; TRYPANOSOMA CRUZI;

EID: 80051937446     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1003911     Document Type: Article

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