TRIM30α negatively regulates TLR-mediated NF-κB activation by targeting TAB2 and TAB3 for degradation

Nature Immunology

Volumn 9, Issue 4, 2008, Pages 369-377

  Shi, Mude ^a   Deng, Weiwen ^a   Bi, Enguang ^a   Mao, Kairui ^a   Ji, Yongyong ^a   Lin, Guomei ^a   Wu, Xiaodong ^a   Tao, Zhiyun ^a   Li, Zhenhu ^a   Cai, Xinfen ^a   Sun, Shuhui ^b   Xiang, Charlie ^c   Sun, Bing ^a,d,e  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b FUDAN UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

^d INSTITUTE PASTEUR OF SHANGHAI   (China)

^e E Institutes of Shanghai Universities   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE BINDING PROTEIN 2; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE BINDING PROTEIN 3; TRIPARTITE MOTIF PROTEIN 30 ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEEDBACK SYSTEM; FEMALE; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; IN VIVO STUDY; INFECTION RESISTANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SEPTIC SHOCK; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE; FEEDBACK, BIOCHEMICAL; FEMALE; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE KINASE KINASES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NF-KAPPA B; TOLL-LIKE RECEPTORS;

EID: 40949163764     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni1577     Document Type: Article

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