Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia

PLoS Pathogens

Volumn 2, Issue 6, 2006, Pages 0526-0535

  Le Goffic, Ronan ^a,b   Balloy, Viviane ^a,b   Lagranderie, Micheline ^a   Alexopoulou, Lena ^b,c,d   Escriou, Nicolas ^d   Flavell, Richard ^e,f   Chignard, Michel ^a,b   Si Tahar, Mustapha ^a,b  

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

^c CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^d CNRS   (France)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 6; RANTES; TOLL LIKE RECEPTOR 3; AUTACOID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; IMMUNE RESPONSE; INFLAMMATION; INFLUENZA VIRUS A; LETHALITY; LEUKOCYTE; LOBAR PNEUMONIA; LUNG ALVEOLUS; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; RESPIRATORY TRACT DISEASE; SURVIVAL; T LYMPHOCYTE; WILD TYPE; ACUTE DISEASE; ANIMAL; BRONCHUS; C57BL MOUSE; KINETICS; LUNG; METABOLISM; MORTALITY; MOUSE MUTANT; ORTHOMYXOVIRUS INFECTION; PATHOLOGY; UPREGULATION; VIROLOGY; VIRUS LOAD; VIRUS PNEUMONIA;

ANIMALIA; INFLUENZA A VIRUS; MURINAE;

ACUTE DISEASE; ANIMALS; BRONCHI; CD8-POSITIVE T-LYMPHOCYTES; INFLAMMATION MEDIATORS; INFLUENZA A VIRUS; KINETICS; LEUKOCYTES; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORTHOMYXOVIRIDAE INFECTIONS; PNEUMONIA, VIRAL; PULMONARY ALVEOLI; SURVIVAL ANALYSIS; TOLL-LIKE RECEPTOR 3; UP-REGULATION; VIRAL LOAD;

EID: 33745684282     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.0020053     Document Type: Article

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