-
1
-
-
68849085894
-
A cell biological view of Toll-like receptor function: Regulation through compartmentalization
-
Barton GM, Kagan JC. A cell biological view of Toll-like receptor function: Regulation through compartmentalization. Nat Rev Immunol 2009; 9: 535-542.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 535-542
-
-
Barton, G.M.1
Kagan, J.C.2
-
3
-
-
77951260924
-
The role of pattern-Recognition receptors in innate immunity: Update on Toll-like receptors
-
Kawai T, Akira S. The role of pattern-Recognition receptors in innate immunity: Update on Toll-like receptors. Nat Immunol 2010; 11: 373-384.
-
(2010)
Nat Immunol
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
4
-
-
32944464648
-
Pathogen recognition and innate immunity
-
DOI 10.1016/j.cell.2006.02.015, PII S0092867406001905
-
Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006; 124: 783-801. (Pubitemid 43261452)
-
(2006)
Cell
, vol.124
, Issue.4
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
6
-
-
79956300649
-
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
-
Kawai T, Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 2011; 34: 637-650.
-
(2011)
Immunity
, vol.34
, pp. 637-650
-
-
Kawai, T.1
Akira, S.2
-
7
-
-
78751560494
-
Pathogen recognition by the innate immune system
-
Kumar H, Kawai T, Akira S. Pathogen recognition by the innate immune system. Int Rev Immunol 2011; 30: 16-34.
-
(2011)
Int Rev Immunol
, vol.30
, pp. 16-34
-
-
Kumar, H.1
Kawai, T.2
Akira, S.3
-
8
-
-
84859986329
-
Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor
-
Jin T, Perry A, Jiang J, Smith P, Curry JA, Unterholzner L et al. Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor. Immunity 2012; 36: 561-571.
-
(2012)
Immunity
, vol.36
, pp. 561-571
-
-
Jin, T.1
Perry, A.2
Jiang, J.3
Smith, P.4
Curry, J.A.5
Unterholzner, L.6
-
9
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR et al. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 2009; 458: 514-518.
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
Bauernfeind, F.4
Horvath, G.5
Caffrey, D.R.6
-
10
-
-
0036088492
-
Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848 [1]
-
DOI 10.1038/ni0602-499
-
Jurk M, Heil F, Vollmer J, Schetter C, Krieg AM, Wagner H et al. Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848. Nat Immunol 2002; 3: 499. (Pubitemid 34669818)
-
(2002)
Nature Immunology
, vol.3
, Issue.6
, pp. 499
-
-
Jurk, M.1
Heil, F.2
Vollmer, J.3
Schetter, C.4
Krieg, A.M.5
Wagner, H.6
Lipford, G.7
Bauer, S.8
-
11
-
-
55449113946
-
Genetic association and expression studies indicate a role of Toll-like receptor 8 in pulmonary tuberculosis
-
Davila S, Hibberd ML, Hari Dass R, Wong HE, Sahiratmadja E, Bonnard C et al. Genetic association and expression studies indicate a role of Toll-like receptor 8 in pulmonary tuberculosis. Plos Genet 2008; 4: E1000218.
-
(2008)
Plos Genet
, vol.4
-
-
Davila, S.1
Hibberd, M.L.2
Hari Dass, R.3
Wong, H.E.4
Sahiratmadja, E.5
Bonnard, C.6
-
12
-
-
77956289822
-
Genetic modulation of TLR8 response following bacterial phagocytosis
-
Gantier MP, Irving AT, Kaparakis-Liaskos M, Xu D, Evans VA, Cameron PU et al. Genetic modulation of TLR8 response following bacterial phagocytosis. Hum Mutat 2010; 31: 1069-1079.
-
(2010)
Hum Mutat
, vol.31
, pp. 1069-1079
-
-
Gantier, M.P.1
Irving, A.T.2
Kaparakis-Liaskos, M.3
Xu, D.4
Evans, V.A.5
Cameron, P.U.6
-
13
-
-
79952750092
-
Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-Beta
-
Cervantes JL, Dunham-Ems SM, la Vake CJ, Petzke MM, Sahay B, Sellati TJ et al. Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-Beta. Proc Natl Acad Sci USA 2011; 108: 3683-3688.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 3683-3688
-
-
Cervantes, J.L.1
Dunham-Ems, S.M.2
La Vake, C.J.3
Petzke, M.M.4
Sahay, B.5
Sellati, T.J.6
-
14
-
-
84868565711
-
Human TLR8 Is activated upon recognition of borrelia burgdorferi rna in the phagosome of human monocytes
-
Cervantes JL, la Vake CJ, Salazar JC. Human TLR8 is activated upon recognition of Borrelia burgdorferi RNA in the phagosome of human monocytes. Cytokine [Abstract]. 2011; 56: 107.
-
(2011)
Cytokine [Abstract
, vol.56
, pp. 107
-
-
Cervantes, J.L.1
La Vake, C.J.2
Salazar, J.C.3
-
15
-
-
42149167357
-
TLR7 is involved in sequence-specific sensing of single-stranded RNAs in human macrophages
-
Gantier MP, Tong S, Behlke MA, Xu D, Phipps S, Foster PS et al. TLR7 is involved in sequence-specific sensing of single-stranded RNAs in human macrophages. J Immunol 2008; 180: 2117-2124.
-
(2008)
J Immunol
, vol.180
, pp. 2117-2124
-
-
Gantier, M.P.1
Tong, S.2
Behlke, M.A.3
Xu, D.4
Phipps, S.5
Foster, P.S.6
-
16
-
-
77949940198
-
Intracellular toll-like receptors
-
Blasius AL, Beutler B. Intracellular toll-like receptors. Immunity 2010; 32: 305-315.
-
(2010)
Immunity
, vol.32
, pp. 305-315
-
-
Blasius, A.L.1
Beutler, B.2
-
17
-
-
77951288057
-
HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells
-
Gringhuis SI, van der Vlist M, van den Berg LM, den Dunnen J, Litjens M, Geijtenbeek TB. HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells. Nat Immunol 2010; 11: 419-426.
-
(2010)
Nat Immunol
, vol.11
, pp. 419-426
-
-
Gringhuis, S.I.1
Van Der Vlist, M.2
Van Den Berg, L.M.3
Den Dunnen, J.4
Litjens, M.5
Geijtenbeek, T.B.6
-
18
-
-
12444341806
-
Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8
-
Gorden KB, Gorski KS, Gibson SJ, Kedl RM, Kieper WC, Qiu X et al. Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8. J Immunol 2005; 174: 1259-1268.
-
(2005)
J Immunol
, vol.174
, pp. 1259-1268
-
-
Gorden, K.B.1
Gorski, K.S.2
Gibson, S.J.3
Kedl, R.M.4
Kieper, W.C.5
Qiu, X.6
-
19
-
-
1542317578
-
Species-Specific Recognition of Single-Stranded RNA via Till-like Receptor 7 and 8
-
DOI 10.1126/science.1093620
-
Heil F, Hemmi H, Hochrein H, Ampenberger F, Kirschning C, Akira S et al. Speciesspecific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 2004; 303: 1526-9. (Pubitemid 38314424)
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
Ampenberger, F.4
Kirschning, C.5
Akira, S.6
Lipford, G.7
Wagner, H.8
Bauer, S.9
-
20
-
-
28244458932
-
A distal regulatory region is required for constitutive and IFN-β-induced expression of murine TLR9 gene
-
Guo Z, Garg S, Hill KM, Jayashankar L, MoOney MR, Hoelscher M et al. A distal regulatory region is required for constitutive and IFN-Beta-induced expression of murine TLR9 gene. J Immunol 2005; 175: 7407-7418. (Pubitemid 41713438)
-
(2005)
Journal of Immunology
, vol.175
, Issue.11
, pp. 7407-7418
-
-
Guo, Z.1
Garg, S.2
Hill, K.M.3
Jayashankar, L.4
Mooney, M.R.5
Hoelscher, M.6
Katz, J.M.7
Boss, J.M.8
Sambhara, S.9
-
22
-
-
0036570169
-
Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
-
Hornung V, Rothenfusser S, Britsch S, Krug A, Jahrsdorfer B, Giese T et al. Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol 2002; 168: 4531-4537. (Pubitemid 34441357)
-
(2002)
Journal of Immunology
, vol.168
, Issue.9
, pp. 4531-4537
-
-
Hornung, V.1
Rothenfusser, S.2
Britsch, S.3
Krug, A.4
Jahrsdorfer, B.5
Giese, T.6
Endres, S.7
Hartmann, G.8
-
23
-
-
38149021578
-
The covalent modification and regulation of TLR8 in HEK-293 cells stimulated with imidazoquinoline agonists
-
Rajagopal R, Waller AS, Mendoza JD, Wightman PD. The covalent modification and regulation of TLR8 in HEK-293 cells stimulated with imidazoquinoline agonists. Biochem J 2008; 409: 275-287.
-
(2008)
Biochem J.
, vol.409
, pp. 275-287
-
-
Rajagopal, R.1
Waller, A.S.2
Mendoza, J.D.3
Wightman, P.D.4
-
24
-
-
40749098665
-
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
-
DOI 10.1038/nature06726, PII NATURE06726
-
Kim YM, Brinkmann MM, Paquet ME, Ploegh HL. UNC93B1 delivers nucleotidesensing toll-like receptors to endolysosomes. Nature 2008; 452: 234-238. (Pubitemid 351380247)
-
(2008)
Nature
, vol.452
, Issue.7184
, pp. 234-238
-
-
Kim, Y.-M.1
Brinkmann, M.M.2
Paquet, M.-E.3
Ploegh, H.L.4
-
25
-
-
82555187209
-
UNC93B1 physically associates with human TLR8 and regulates TLR8-mediated signaling
-
Itoh H, Tatematsu M, Watanabe A, Iwano K, Funami K, Seya T et al. UNC93B1 physically associates with human TLR8 and regulates TLR8-mediated signaling. Plos One 2011; 6: E28500.
-
(2011)
Plos One
, vol.6
-
-
Itoh, H.1
Tatematsu, M.2
Watanabe, A.3
Iwano, K.4
Funami, K.5
Seya, T.6
-
26
-
-
67349187318
-
Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells
-
Mancuso G, Gambuzza M, Midiri A, Biondo C, Papasergi S, Akira S et al. Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells. Nat Immunol 2009; 10: 587-594.
-
(2009)
Nat Immunol
, vol.10
, pp. 587-594
-
-
Mancuso, G.1
Gambuzza, M.2
Midiri, A.3
Biondo, C.4
Papasergi, S.5
Akira, S.6
-
27
-
-
70349245386
-
Bacterial RNA is recognized by different sets of immunoreceptors
-
Eberle F, Sirin M, Binder M, Dalpke AH. Bacterial RNA is recognized by different sets of immunoreceptors. Eur J Immunol 2009; 39: 2537-2547.
-
(2009)
Eur J Immunol
, vol.39
, pp. 2537-2547
-
-
Eberle, F.1
Sirin, M.2
Binder, M.3
Dalpke, A.H.4
-
28
-
-
23844464444
-
Suppression of RNA recognition by Toll-like receptors: The impact of nucleoside modification and the evolutionary origin of RNA
-
DOI 10.1016/j.immuni.2005.06.008, PII S1074761305002116
-
Kariko K, Buckstein M, Ni H, Weissman D. Suppression ofRNArecognition by Toll-like receptors: The impact of nucleoside modification and the evolutionary origin of RNA. Immunity 2005; 23: 165-175. (Pubitemid 41169286)
-
(2005)
Immunity
, vol.23
, Issue.2
, pp. 165-175
-
-
Kariko, K.1
Buckstein, M.2
Ni, H.3
Weissman, D.4
-
29
-
-
67249115186
-
Activation of human monocytes by live Borrelia burgdorferi generates TLR2-dependent and -independent responses which include induction of IFN-Beta
-
Salazar JC, Duhnam-Ems S, la Vake C, Cruz AR, Moore MW, Caimano MJ et al. Activation of human monocytes by live Borrelia burgdorferi generates TLR2-dependent and -independent responses which include induction of IFN-Beta. Plos Pathog 2009; 5: E1000444.
-
(2009)
Plos Pathog
, vol.5
-
-
Salazar, J.C.1
Duhnam-Ems, S.2
La Vake, C.3
Cruz, A.R.4
Moore, M.W.5
Caimano, M.J.6
-
30
-
-
75749141369
-
Intrinsic cellular defenses against virus infection by antiviral type I interferon
-
Boo KH, Yang JS. Intrinsic cellular defenses against virus infection by antiviral type I interferon. Yonsei Med J 2010; 51: 9-17.
-
(2010)
Yonsei Med J.
, vol.51
, pp. 9-17
-
-
Boo, K.H.1
Yang, J.S.2
-
31
-
-
84863115824
-
The 29-O-methylation status of a single guanosine controls transfer RNA-mediated Toll-like receptor 7 activation or inhibition
-
Jockel S, Nees G, Sommer R, Zhao Y, Cherkasov D, Hori H et al. The 29-O-methylation status of a single guanosine controls transfer RNA-mediated Toll-like receptor 7 activation or inhibition. J Exp Med 2012; 209: 235-241.
-
(2012)
J Exp Med
, vol.209
, pp. 235-241
-
-
Jockel, S.1
Nees, G.2
Sommer, R.3
Zhao, Y.4
Cherkasov, D.5
Hori, H.6
-
32
-
-
43449132981
-
Porcine TLR8 and TLR7 are both activated by a selective TLR7 ligand, imiquimod
-
Zhu J, Lai K, Brownile R, Babiuk LA, Mutwiri GK. Porcine TLR8 and TLR7 are both activated by a selective TLR7 ligand, imiquimod. Mol Immunol 2008; 45: 3238-3243.
-
(2008)
Mol Immunol
, vol.45
, pp. 3238-3243
-
-
Zhu, J.1
Lai, K.2
Brownile, R.3
Babiuk, L.A.4
Mutwiri, G.K.5
-
33
-
-
44649137559
-
Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses
-
Forsbach A, Nemorin JG, Montino C, Muller C, Samulowitz U, Vicari AP et al. Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses. J Immunol 2008; 180: 3729-3738.
-
(2008)
J Immunol
, vol.180
, pp. 3729-3738
-
-
Forsbach, A.1
Nemorin, J.G.2
Montino, C.3
Muller, C.4
Samulowitz, U.5
Vicari, A.P.6
-
34
-
-
33750823681
-
Cutting edge: Activation of murine TLR8 by a combination of imidazoquinoline immune response modifiers and polyT oligodeoxynucleotides
-
Gorden KK, Qiu XX, Binsfeld CC, Vasilakos JP, Alkan SS. Cutting edge: Activation of murine TLR8 by a combination of imidazoquinoline immune response modifiers and polyT oligodeoxynucleotides. J Immunol 2006; 177: 6584-6587. (Pubitemid 44715019)
-
(2006)
Journal of Immunology
, vol.177
, Issue.10
, pp. 6584-6587
-
-
Gorden, K.K.B.1
Qiu, X.X.2
Binsfeld, C.C.A.3
Vasilakos, J.P.4
Alkan, S.S.5
-
35
-
-
77950883727
-
Toll-like receptor 8-mediated activation of murine plasmacytoid dendritic cells by vaccinia viral DNA
-
Martinez J, Huang X, Yang Y. Toll-like receptor 8-mediated activation of murine plasmacytoid dendritic cells by vaccinia viral DNA. Proc Natl Acad Sci USA 2010; 107: 6442-6447.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 6442-6447
-
-
Martinez, J.1
Huang, X.2
Yang, Y.3
-
36
-
-
77957673545
-
A major role for TLR8 in the recognition of vaccinia viral DNA by murine pDC
-
author reply E40
-
Bauer S, Bathke B, Lauterbach H, Patzold J, Kassub R, Luber CA et al. A major role for TLR8 in the recognition of vaccinia viral DNA by murine pDC? Proc Natl Acad Sci USA 2010; 107: E139; author reply E40.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
-
-
Bauer, S.1
Bathke, B.2
Lauterbach, H.3
Patzold, J.4
Kassub, R.5
Luber, C.A.6
-
37
-
-
34250011263
-
TLR-TLR cross talk in human PBMC resulting in synergistic and antagonistic regulation of type-1 and 2 interferons, IL-12 and TNF-α
-
DOI 10.1016/j.intimp.2007.04.006, PII S1567576907001099
-
Ghosh TK, Mickelson DJ, Solberg JC, Lipson KE, Inglefield JR, Alkan SS. TLR-TLR cross talk in human PBMC resulting in synergistic and antagonistic regulation of type-1 and 2 interferons, IL-12 and TNF-alpha. Int Immunopharmacol 2007; 7: 1111-1121. (Pubitemid 46891328)
-
(2007)
International Immunopharmacology
, vol.7
, Issue.8
, pp. 1111-1121
-
-
Ghosh, T.K.1
Mickelson, D.J.2
Solberg, J.C.3
Lipson, K.E.4
Inglefield, J.R.5
Alkan, S.S.6
-
38
-
-
23944489407
-
Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1 -polarizing program in dendritic cells
-
DOI 10.1038/ni1223, PII N1223
-
Napolitani G, Rinaldi A, Bertoni F, Sallusto F, Lanzavecchia A. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-Polarizing program in dendritic cells. Nat Immunol 2005; 6: 769-776. (Pubitemid 43090462)
-
(2005)
Nature Immunology
, vol.6
, Issue.8
, pp. 769-776
-
-
Napolitani, G.1
Rinaldi, A.2
Bertoni, F.3
Sallusto, F.4
Lanzavecchia, A.5
-
39
-
-
65249164025
-
Multiple signaling pathways contribute to synergistic TLR ligand-dependent cytokine gene expression in human monocyte-derived macrophages and dendritic cells
-
Makela SM, Strengell M, Pietila TE, Osterlund P, Julkunen I. Multiple signaling pathways contribute to synergistic TLR ligand-dependent cytokine gene expression in human monocyte-derived macrophages and dendritic cells. J Leukoc Biol 2009; 85: 664-672.
-
(2009)
J Leukoc Biol
, vol.85
, pp. 664-672
-
-
Makela, S.M.1
Strengell, M.2
Pietila, T.E.3
Osterlund, P.4
Julkunen, I.5
-
40
-
-
84875257261
-
TLR8 and NOD signaling synergistically induce the production of IL-1beta and IL-23 in monocytederived DCs and enhance the expression of the feedback inhibitor SOCS2
-
Schwarz H, Posselt G, Wurm P, Ulbing M, Duschl A, Horejs-Hoeck J. TLR8 and NOD signaling synergistically induce the production of IL-1beta and IL-23 in monocytederived DCs and enhance the expression of the feedback inhibitor SOCS2. Immunobiology 2012.
-
(2012)
Immunobiology
-
-
Schwarz, H.1
Posselt, G.2
Wurm, P.3
Ulbing, M.4
Duschl, A.5
Horejs-Hoeck, J.6
-
41
-
-
77954759074
-
Exposure To HIV-1-encoded toll-like receptor 8 ligands enhances monocyte response to microbial encoded tolllike receptor 24 ligands
-
Mureith MW, Chang JJ, Lifson JD, Ndung9u T, Altfeld M. Exposure to HIV-1-encoded Toll-like receptor 8 ligands enhances monocyte response to microbial encoded Tolllike receptor 2/4 ligands. AIDS 2010; 24: 1841-8.
-
(2010)
AIDS
, vol.24
, pp. 1841-1848
-
-
Mureith, M.W.1
Chang, J.J.2
Lifson, J.D.3
Ndungu, T.4
Altfeld, M.5
-
42
-
-
80054020359
-
The TLR7/8 ligand resiquimod targets monocyte-derived dendritic cell differentiation via TLR8 and augments functional dendritic cell generation
-
Hackstein H, Knoche A, Nockher A, Poeling J, Kubin T, JurkMet al. The TLR7/8 ligand resiquimod targets monocyte-derived dendritic cell differentiation via TLR8 and augments functional dendritic cell generation. Cell Immunol 2011; 271: 401-412.
-
(2011)
Cell Immunol
, vol.271
, pp. 401-412
-
-
Hackstein, H.1
Knoche, A.2
Nockher, A.3
Poeling, J.4
Kubin, T.5
Jurk, M.6
-
43
-
-
0033566734
-
Activation of human monocytic cells by Borrelia burgdorferi and Treponema pallidum is facilitated by CD14 and correlates with surface exposure of spirochetal lipoproteins
-
Sellati TJ, Bouis DA, Caimano MJ, Feulner JA, Ayers C, Lien E et al. Activation of human monocytic cells by Borrelia burgdorferi and TrepOnema pallidum is facilitated by CD14 and correlates with surface exposure of spirochetal lipoproteins. J Immunol 1999; 163: 2049-2056. (Pubitemid 29382209)
-
(1999)
Journal of Immunology
, vol.163
, Issue.4
, pp. 2049-2056
-
-
Sellati, T.J.1
Bouis, D.A.2
Caimano, M.J.3
Feulner, J.A.4
Ayers, C.5
Lien, E.6
Radolf, J.D.7
-
44
-
-
0033618630
-
Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2
-
Aliprantis AO, Yang RB, Mark MR, Suggett S, Devaux B, Radolf JD et al. Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. Science 1999; 285: 736-739.
-
(1999)
Science
, vol.285
, pp. 736-739
-
-
Aliprantis, A.O.1
Yang, R.B.2
Mark, M.R.3
Suggett, S.4
Devaux, B.5
Radolf, J.D.6
-
45
-
-
0033198204
-
Cutting edge: Inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2
-
Hirschfeld M, Kirschning CJ, Schwandner R, Wesche H, Weis JH, Wooten RM et al. Cutting edge: Inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2. J Immunol 1999; 163: 2382-2386. (Pubitemid 29399155)
-
(1999)
Journal of Immunology
, vol.163
, Issue.5
, pp. 2382-2386
-
-
Hirschfeld, M.1
Kirschning, G.J.2
Schwandner, R.3
Wesche, H.4
Weis, J.H.5
Wooten, R.M.6
Weis, J.J.7
-
46
-
-
78650542756
-
Association between tolllike receptor expression and human papillomavirus type 16 persistence
-
Daud II, Scott ME, Ma Y, Shiboski S, Farhat S, Moscicki AB. Association between tolllike receptor expression and human papillomavirus type 16 persistence. Int J Cancer 2011; 128: 879-886.
-
(2011)
Int J Cancer
, vol.128
, pp. 879-886
-
-
Daud, I.I.1
Scott, M.E.2
Ma, Y.3
Shiboski, S.4
Farhat, S.5
Moscicki, A.B.6
-
47
-
-
33846000646
-
The functional effects of physical interactions among toll-like receptors 7, 8, and 9
-
DOI 10.1074/jbc.M605311200
-
Wang J, Shao Y, Bennett TA, Shankar RA, Wightman PD, Reddy LG. The functional effects of physical interactions among Toll-like receptors 7, 8, and 9. J Biol Chem 2006; 281: 37427-37434. (Pubitemid 46042046)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.49
, pp. 37427-37434
-
-
Wang, J.1
Shao, Y.2
Bennett, T.A.3
Shankar, R.A.4
Wightman, P.D.5
Reddy, L.G.6
-
48
-
-
77957845606
-
TLR8 deficiency leads to autoimmunity in mice
-
Demaria O, Pagni PP, Traub S, de Gassart A, Branzk N, Murphy AJ et al. TLR8 deficiency leads to autoimmunity in mice. J Clin Invest 2010; 120: 3651-3662.
-
(2010)
J Clin Invest
, vol.120
, pp. 3651-3662
-
-
Demaria, O.1
Pagni, P.P.2
Traub, S.3
De Gassart, A.4
Branzk, N.5
Murphy, A.J.6
-
49
-
-
77955307228
-
Expression of Toll-like receptors 7, 8, and 9 in primary Sjogren's syndrome
-
Zheng L, Zhang Z, Yu C, Yang C. Expression of Toll-like receptors 7, 8, and 9 in primary Sjogren's syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 109: 844-850.
-
(2010)
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
, vol.109
, pp. 844-850
-
-
Zheng, L.1
Zhang, Z.2
Yu, C.3
Yang, C.4
-
50
-
-
0034457684
-
Cloning and characterization of a sub-family of human Toll-like receptors: HTLR7, hTLR8 and hTLR9
-
Chuang TH, Ulevitch RJ. Cloning and characterization of a sub-family of human tolllike receptors: HTLR7, hTLR8 and hTLR9. Eur Cytokine Netw 2000; 11: 372-378. (Pubitemid 32268894)
-
(2000)
European Cytokine Network
, vol.11
, Issue.3
, pp. 372-378
-
-
Chuang, T.-H.1
Ulevitch, R.J.2
-
51
-
-
0034456693
-
Three novel mammalian toll-like receptors: Gene structure, expression, and evolution
-
Du X, Poltorak A, Wei Y, Beutler B. Three novel mammalian toll-like receptors: Gene structure, expression, and evolution. Eur Cytokine Netw 2000; 11: 362-371. (Pubitemid 32268893)
-
(2000)
European Cytokine Network
, vol.11
, Issue.3
, pp. 362-371
-
-
Du, X.1
Poltorak, A.2
Wei, Y.3
Beutler, B.4
-
52
-
-
50949083798
-
A functional toll-like receptor 8 variant is associated with HIV disease restriction
-
Oh DY, Taube S, Hamouda O, Kucherer C, Poggensee G, Jessen H et al. A functional toll-like receptor 8 variant is associated with HIV disease restriction. J Infect Dis 2008; 198: 701-709.
-
(2008)
J Infect Dis
, vol.198
, pp. 701-709
-
-
Oh, D.Y.1
Taube, S.2
Hamouda, O.3
Kucherer, C.4
Poggensee, G.5
Jessen, H.6
-
53
-
-
33847789122
-
The CD14+ CD16+ blood monocytes: Their role in infection and inflammation
-
DOI 10.1189/jlb.0806510
-
Ziegler-Heitbrock L. The CD141CD161 blood monocytes: Their role in infection and inflammation. J Leukoc Biol 2007; 81: 584-592. (Pubitemid 46393535)
-
(2007)
Journal of Leukocyte Biology
, vol.81
, Issue.3
, pp. 584-592
-
-
Ziegler-Heitbrock, L.1
-
54
-
-
84865032889
-
New developments in Toll-like receptor targeted therapeutics
-
Connolly DJ, O'Neill LA. New developments in Toll-like receptor targeted therapeutics. Curr Opin Pharmacol 2012; 12: 510-518.
-
(2012)
Curr Opin Pharmacol
, vol.12
, pp. 510-518
-
-
Connolly, D.J.1
O'Neill, L.A.2
-
55
-
-
35348990231
-
Resiquimod and other immune response modifiers as vaccine adjuvants
-
DOI 10.1586/14760584.6.5.835
-
Tomai MA, Miller RL, Lipson KE, Kieper WC, Zarraga IE, Vasilakos JP. Resiquimod and other immune response modifiers as vaccine adjuvants. Expert Rev Vaccines 2007; 6: 835-847. (Pubitemid 47607857)
-
(2007)
Expert Review of Vaccines
, vol.6
, Issue.5
, pp. 835-847
-
-
Tomai, M.A.1
Miller, R.L.2
Lipson, K.E.3
Kieper, W.C.4
Zarraga, I.E.5
Vasilakos, J.P.6
-
56
-
-
77955656853
-
TLR8 agonists stimulate newly recruited monocyte-derived cells into potent APCs that enhance HBsAg immunogenicity
-
Du J, Wu Z, Ren S, Wei Y, Gao M, Randolph GJ et al. TLR8 agonists stimulate newly recruited monocyte-derived cells into potent APCs that enhance HBsAg immunogenicity. Vaccine 2010; 28: 6273-6281.
-
(2010)
Vaccine
, vol.28
, pp. 6273-6281
-
-
Du, J.1
Wu, Z.2
Ren, S.3
Wei, Y.4
Gao, M.5
Randolph, G.J.6
-
57
-
-
34249677845
-
Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
-
DOI 10.1038/nm1589, PII NM1589
-
Kanzler H, Barrat FJ, Hessel EM, Coffman RL. Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists. Nat Med 2007; 13: 552-559. (Pubitemid 46830615)
-
(2007)
Nature Medicine
, vol.13
, Issue.5
, pp. 552-559
-
-
Kanzler, H.1
Barrat, F.J.2
Hessel, E.M.3
Coffman, R.L.4
-
58
-
-
84862907802
-
VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC
-
Lu H, Dietsch GN, Matthews MA, Yang Y, Ghanekar S, InokumaMet al. VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC. Clin Cancer Res 2012; 18: 499-509.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 499-509
-
-
Lu, H.1
Dietsch, G.N.2
Matthews, M.A.3
Yang, Y.4
Ghanekar, S.5
Inokuma, M.6
-
59
-
-
79958832035
-
VTX-1463, a novel TLR8 agonist for the treatment of allergic rhinitis
-
Horak F. VTX-1463, a novel TLR8 agonist for the treatment of allergic rhinitis. Expert Opin Investig Drugs 2011; 20: 981-986.
-
(2011)
Expert Opin Investig Drugs
, vol.20
, pp. 981-986
-
-
Horak, F.1
-
60
-
-
27244443079
-
+ T cell responses in nonhuman primates
-
DOI 10.1073/pnas.0507484102
-
Wille-Reece U, Flynn BJ, Lore K, Koup RA, Kedl RM, Mattapallil JJ et al. HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD81 T cell responses in nonhuman primates. Proc Natl Acad Sci USA 2005; 102: 15190-15194. (Pubitemid 41513357)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.42
, pp. 15190-15194
-
-
Wille-Reece, U.1
Flynn, B.J.2
Lore, K.3
Koup, R.A.4
Kedl, R.M.5
Mattapallil, J.J.6
Weiss, W.R.7
Roederer, M.8
Seder, R.A.9
-
61
-
-
84855756265
-
R-848 triggers the expression of TLR7/8 and suppresses HIV replication in monocytes
-
Nian H, Geng WQ, Cui HL, Bao MJ, Zhang ZN, Zhang M et al. R-848 triggers the expression of TLR7/8 and suppresses HIV replication in monocytes. BMC Infect Dis 2012; 12: 5.
-
(2012)
BMC Infect Dis
, vol.12
, pp. 5
-
-
Nian, H.1
Geng, W.Q.2
Cui, H.L.3
Bao, M.J.4
Zhang, Z.N.5
Zhang, M.6
-
62
-
-
79959242498
-
Detection of prokaryotic mRNA signifies microbial viability and promotes immunity
-
Sander LE, Davis MJ, Boekschoten MV, Amsen D, Dascher CC, RyffelBet al. Detection of prokaryotic mRNA signifies microbial viability and promotes immunity. Nature 2011; 474: 385-389.
-
(2011)
Nature
, vol.474
, pp. 385-389
-
-
Sander, L.E.1
Davis, M.J.2
Boekschoten, M.V.3
Amsen, D.4
Dascher, C.C.5
Ryffel, B.6
-
63
-
-
74549167783
-
Regulation of adaptive immunity by the innate immune system
-
Iwasaki A, Medzhitov R. Regulation of adaptive immunity by the innate immune system. Science 2010; 327: 291-295.
-
(2010)
Science
, vol.327
, pp. 291-295
-
-
Iwasaki, A.1
Medzhitov, R.2
-
64
-
-
37649018614
-
Toll-like receptors and autoimmunity
-
Hurst J, von Landenberg P. Toll-like receptors and autoimmunity. Autoimmun Rev 2008; 7: 204-208
-
(2008)
Autoimmun Rev
, vol.7
, pp. 204-208
-
-
Hurst, J.1
Von Landenberg, P.2
|