-
1
-
-
0027515616
-
Aging and resistance to oxidative damage in Caenorhabditis elegans
-
Larsen, P. L. (1993) Aging and resistance to oxidative damage in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A. 90, 8905-8909
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 8905-8909
-
-
Larsen, P.L.1
-
2
-
-
0032582489
-
Extended life-span and stress resistance in the Drosophila mutant methuselah
-
Lin, Y. J., Seroude, L., and Benzer, S. (1998) Extended life-span and stress resistance in the Drosophila mutant methuselah. Science 282, 943-946
-
(1998)
Science
, vol.282
, pp. 943-946
-
-
Lin, Y.J.1
Seroude, L.2
Benzer, S.3
-
3
-
-
0029920370
-
Genetic analysis of ageing: Role of oxidative damage and environmental stresses
-
Martin, G. M., Austad, S. N., and Johnson, T. E. (1996) Genetic analysis of ageing: role of oxidative damage and environmental stresses. Nat. Genet. 13, 25-34
-
(1996)
Nat. Genet.
, vol.13
, pp. 25-34
-
-
Martin, G.M.1
Austad, S.N.2
Johnson, T.E.3
-
4
-
-
0029952098
-
Dwarf mice and the ageing process
-
Brown-Borg, H. M., Borg, K. E., Meliska, C. J., and Bartke, A. (1996) Dwarf mice and the ageing process. Nature 384, 33
-
(1996)
Nature
, vol.384
, pp. 33
-
-
Brown-Borg, H.M.1
Borg, K.E.2
Meliska, C.J.3
Bartke, A.4
-
5
-
-
0035811073
-
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production
-
Flurkey, K., Papaconstantinou, J., Miller, R. A., and Harrison, D. E. (2001) Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production. Proc. Natl. Acad. Sci. U. S. A. 98, 6736-6741
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 6736-6741
-
-
Flurkey, K.1
Papaconstantinou, J.2
Miller, R.A.3
Harrison, D.E.4
-
6
-
-
23844551318
-
Minireview: Role of the growth hormone/insulin-like growth factor system in mammalian aging
-
Bartke, A. (2005) Minireview: role of the growth hormone/insulin-like growth factor system in mammalian aging. Endocrinology 146, 3718-3723
-
(2005)
Endocrinology
, vol.146
, pp. 3718-3723
-
-
Bartke, A.1
-
7
-
-
0345237923
-
Delayed occurrence of fatal neoplastic diseases in ames dwarf mice: Correlation to extended longevity
-
Ikeno, Y., Bronson, R. T., Hubbard, G. B., Lee, S., and Bartke, A. (2003) Delayed occurrence of fatal neoplastic diseases in ames dwarf mice: correlation to extended longevity. J. Gerontol. A Biol. Sci. Med. Sci. 58, 291-296
-
(2003)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.58
, pp. 291-296
-
-
Ikeno, Y.1
Bronson, R.T.2
Hubbard, G.B.3
Lee, S.4
Bartke, A.5
-
8
-
-
0034966342
-
Evidence that Ames dwarf mice age differently from their normal siblings in behavioral and learning and memory parameters
-
Kinney, B. A., Meliska, C. J., Steger, R. W., and Bartke, A. (2001) Evidence that Ames dwarf mice age differently from their normal siblings in behavioral and learning and memory parameters. Horm. Behav. 39, 277-284
-
(2001)
Horm. Behav.
, vol.39
, pp. 277-284
-
-
Kinney, B.A.1
Meliska, C.J.2
Steger, R.W.3
Bartke, A.4
-
9
-
-
0042203536
-
Multiplex stress resistance in cells from long-lived dwarf mice
-
Murakami, S., Salmon, A., and Miller, R. A. (2003) Multiplex stress resistance in cells from long-lived dwarf mice. FASEB J. 17, 1565-1566
-
(2003)
FASEB J.
, vol.17
, pp. 1565-1566
-
-
Murakami, S.1
Salmon, A.2
Miller, R.A.3
-
10
-
-
21044450084
-
Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress
-
Salmon, A. B., Murakami, S., Bartke, A., Kopchick, J., Yasumura, K., and Miller, R. A. (2005) Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress. Am. J. Physiol. Endocrinol. Metab. 289, E23-29
-
(2005)
Am. J. Physiol. Endocrinol. Metab.
, vol.289
-
-
Salmon, A.B.1
Murakami, S.2
Bartke, A.3
Kopchick, J.4
Yasumura, K.5
Miller, R.A.6
-
11
-
-
33644796631
-
Fibroblasts from long-lived Snell dwarf mice are resistant to oxygen-induced in vitro growth arrest
-
Maynard, S. P., and Miller, R. A. (2006) Fibroblasts from long-lived Snell dwarf mice are resistant to oxygen-induced in vitro growth arrest. Aging Cell 5, 89-96
-
(2006)
Aging Cell
, vol.5
, pp. 89-96
-
-
Maynard, S.P.1
Miller, R.A.2
-
12
-
-
44349145957
-
Cells from long-lived mutant mice exhibit enhanced repair of ultraviolet lesions
-
Salmon, A. B., Ljungman, M., and Miller, R. A. (2008) Cells from long-lived mutant mice exhibit enhanced repair of ultraviolet lesions. J. Gerontol. A Biol. Sci. Med. Sci. 63, 219-231
-
(2008)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.63
, pp. 219-231
-
-
Salmon, A.B.1
Ljungman, M.2
Miller, R.A.3
-
13
-
-
67650649527
-
Long-lived ames dwarf mice are resistant to chemical stressors
-
Bokov, A. F., Lindsey, M. L., Khodr, C., Sabia, M. R., and Richardson, A. (2009) Long-lived ames dwarf mice are resistant to chemical stressors. J. Gerontol. A Biol. Sci. Med. Sci. 64, 819-827
-
(2009)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.64
, pp. 819-827
-
-
Bokov, A.F.1
Lindsey, M.L.2
Khodr, C.3
Sabia, M.R.4
Richardson, A.5
-
14
-
-
0034001572
-
Mechanisms of toxicity, clinical features, and management of diquat poisoning: A review
-
Jones, G. M., and Vale, J. A. (2000) Mechanisms of toxicity, clinical features, and management of diquat poisoning: a review. J. Toxicol. Clin. Toxicol. 38, 123-128
-
(2000)
J. Toxicol. Clin. Toxicol.
, vol.38
, pp. 123-128
-
-
Jones, G.M.1
Vale, J.A.2
-
15
-
-
0015821035
-
Bipyridylium quaternary salts and related compounds. V. Pulse radiolysis studies of the reaction of paraquat radical with oxygen. Implications for the mode of action of bipyridyl herbicides
-
Farrington, J. A., Ebert, M., Land, E. J., and Fletcher, K. (1973) Bipyridylium quaternary salts and related compounds. V. Pulse radiolysis studies of the reaction of paraquat radical with oxygen. Implications for the mode of action of bipyridyl herbicides. Biochim. Biophys. Acta 314, 372-381
-
(1973)
Biochim. Biophys. Acta
, vol.314
, pp. 372-381
-
-
Farrington, J.A.1
Ebert, M.2
Land, E.J.3
Fletcher, K.4
-
16
-
-
0035282334
-
Mammalian MAP kinase signalling cascades
-
DOI 10.1038/35065000
-
Chang, L., and Karin, M. (2001) Mammalian MAP kinase signalling cascades. Nature 410, 37-40 (Pubitemid 32225829)
-
(2001)
Nature
, vol.410
, Issue.6824
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
17
-
-
41549160315
-
Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival
-
Junttila, M. R., Li, S. P., and Westermarck, J. (2008) Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival. FASEB J. 22, 954-965
-
(2008)
FASEB J.
, vol.22
, pp. 954-965
-
-
Junttila, M.R.1
Li, S.P.2
Westermarck, J.3
-
18
-
-
70449523451
-
Fibroblasts from long-lived mutant mice show diminished ERK1/2 phosphorylation but exaggerated induction of immediate early genes
-
Sun, L. Y., Steinbaugh, M. J., Masternak, M. M., Bartke, A., and Miller, R. A. (2009) Fibroblasts from long-lived mutant mice show diminished ERK1/2 phosphorylation but exaggerated induction of immediate early genes. Free Radic. Biol. Med. 47, 1753-1761
-
(2009)
Free Radic. Biol. Med.
, vol.47
, pp. 1753-1761
-
-
Sun, L.Y.1
Steinbaugh, M.J.2
Masternak, M.M.3
Bartke, A.4
Miller, R.A.5
-
19
-
-
77956533160
-
Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS)
-
Hsieh, C. C., and Papaconstantinou, J. (2009) Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS). Aging 1, 784-802
-
(2009)
Aging
, vol.1
, pp. 784-802
-
-
Hsieh, C.C.1
Papaconstantinou, J.2
-
20
-
-
70349843323
-
Nrf2:INrf2 (Keap1) signaling in oxidative stress
-
Kaspar, J. W., Niture, S. K., and Jaiswal, A. K. (2009) Nrf2:INrf2 (Keap1) signaling in oxidative stress. Free Radic. Biol. Med. 47, 1304-1309
-
(2009)
Free Radic. Biol. Med.
, vol.47
, pp. 1304-1309
-
-
Kaspar, J.W.1
Niture, S.K.2
Jaiswal, A.K.3
-
21
-
-
14044254798
-
Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation
-
Kobayashi, M., and Yamamoto, M. (2005) Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation. Antioxid. Redox Signal. 7, 385-394
-
(2005)
Antioxid. Redox Signal.
, vol.7
, pp. 385-394
-
-
Kobayashi, M.1
Yamamoto, M.2
-
22
-
-
75149117017
-
Nrf2 signaling, a mechanism for cellular stress resistance in long-lived mice
-
Leiser, S. F., and Miller, R. A. Nrf2 signaling, a mechanism for cellular stress resistance in long-lived mice. Mol. Cell. Biol. 30, 871-884
-
Mol. Cell. Biol.
, vol.30
, pp. 871-884
-
-
Leiser, S.F.1
Miller, R.A.2
-
23
-
-
33751234510
-
Insulin-like growth factor-I stimulates histone H3 and H4 acetylation in the brain in vivo
-
Sun, L. Y., and D'Ercole, A. J. (2006) Insulin-like growth factor-I stimulates histone H3 and H4 acetylation in the brain in vivo. Endocrinology 147, 5480-5490
-
(2006)
Endocrinology
, vol.147
, pp. 5480-5490
-
-
Sun, L.Y.1
D'Ercole, A.J.2
-
24
-
-
0036888651
-
Regulation of life and death by the zinc finger transcription factor Egr-1
-
Thiel, G., and Cibelli, G. (2002) Regulation of life and death by the zinc finger transcription factor Egr-1. J. Cell. Physiol. 193, 287-292
-
(2002)
J. Cell. Physiol.
, vol.193
, pp. 287-292
-
-
Thiel, G.1
Cibelli, G.2
-
25
-
-
54049120274
-
Stimulation of macrophage TNFalpha production by orthopaedic wear particles requires activation of the ERK1/2/Egr-1 and NF-kappaB pathways but is independent of p38 and JNK
-
Beidelschies, M. A., Huang, H., McMullen, M. R., Smith, M. V., Islam, A. S., Goldberg, V. M., Chen, X., Nagy, L. E., and Greenfield, E. M. (2008) Stimulation of macrophage TNFalpha production by orthopaedic wear particles requires activation of the ERK1/2/Egr-1 and NF-kappaB pathways but is independent of p38 and JNK. J. Cell. Physiol. 217, 652-666
-
(2008)
J. Cell. Physiol.
, vol.217
, pp. 652-666
-
-
Beidelschies, M.A.1
Huang, H.2
McMullen, M.R.3
Smith, M.V.4
Islam, A.S.5
Goldberg, V.M.6
Chen, X.7
Nagy, L.E.8
Greenfield, E.M.9
-
26
-
-
58149250928
-
Convergence of integrins and EGF receptor signaling via PI3K/Akt/FoxO pathway in early gene Egr-1 expression
-
Cabodi, S., Morello, V., Masi, A., Cicchi, R., Broggio, C., Distefano, P., Brunelli, E., Silengo, L., Pavone, F., Arcangeli, A., Turco, E., Tarone, G., Moro, L., and Defilippi, P. (2009) Convergence of integrins and EGF receptor signaling via PI3K/Akt/FoxO pathway in early gene Egr-1 expression. J. Cell. Physiol. 218, 294-303
-
(2009)
J. Cell. Physiol.
, vol.218
, pp. 294-303
-
-
Cabodi, S.1
Morello, V.2
Masi, A.3
Cicchi, R.4
Broggio, C.5
Distefano, P.6
Brunelli, E.7
Silengo, L.8
Pavone, F.9
Arcangeli, A.10
Turco, E.11
Tarone, G.12
Moro, L.13
Defilippi, P.14
-
27
-
-
4644303022
-
Human glutamate cysteine ligase gene regulation through the electrophile response element
-
Dickinson, D. A., Levonen, A. L., Moellering, D. R., Arnold, E. K., Zhang, H., Darley-Usmar, V. M., and Forman, H. J. (2004) Human glutamate cysteine ligase gene regulation through the electrophile response element. Free Radic. Biol. Med. 37, 1152-1159
-
(2004)
Free Radic. Biol. Med.
, vol.37
, pp. 1152-1159
-
-
Dickinson, D.A.1
Levonen, A.L.2
Moellering, D.R.3
Arnold, E.K.4
Zhang, H.5
Darley-Usmar, V.M.6
Forman, H.J.7
-
28
-
-
67349252035
-
Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease
-
Morse, D., Lin, L., Choi, A. M., and Ryter, S. W. (2009) Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease. Free Radic. Biol. Med. 47, 1-12
-
(2009)
Free Radic. Biol. Med.
, vol.47
, pp. 1-12
-
-
Morse, D.1
Lin, L.2
Choi, A.M.3
Ryter, S.W.4
-
29
-
-
48549090696
-
Carbon monoxide, reactive oxygen signaling, and oxidative stress
-
Piantadosi, C. A. (2008) Carbon monoxide, reactive oxygen signaling, and oxidative stress. Free Radic. Biol. Med. 45, 562-569
-
(2008)
Free Radic. Biol. Med.
, vol.45
, pp. 562-569
-
-
Piantadosi, C.A.1
-
30
-
-
40949107656
-
Structure, function, and mechanism of cytosolic quinone reductases
-
Bianchet, M. A., Erdemli, S. B., and Amzel, L. M. (2008) Structure, function, and mechanism of cytosolic quinone reductases. Vitam. Horm. 78, 63-84
-
(2008)
Vitam. Horm.
, vol.78
, pp. 63-84
-
-
Bianchet, M.A.1
Erdemli, S.B.2
Amzel, L.M.3
-
31
-
-
73349133007
-
Thioredoxins and glutaredoxins: Unifying elements in redox biology
-
Meyer, Y., Buchanan, B. B., Vignols, F., and Reichheld, J. P. (2009) Thioredoxins and glutaredoxins: unifying elements in redox biology. Annu. Rev. Genet. 43, 335-367
-
(2009)
Annu. Rev. Genet.
, vol.43
, pp. 335-367
-
-
Meyer, Y.1
Buchanan, B.B.2
Vignols, F.3
Reichheld, J.P.4
-
32
-
-
33846945701
-
Carbonyl reductases: The complex relationships of mammalian carbonyl- and quinone-reducing enzymes and their role in physiology
-
Oppermann, U. (2007) Carbonyl reductases: the complex relationships of mammalian carbonyl- and quinone-reducing enzymes and their role in physiology. Annu. Rev. Pharmacol. Toxicol. 47, 293-322
-
(2007)
Annu. Rev. Pharmacol. Toxicol.
, vol.47
, pp. 293-322
-
-
Oppermann, U.1
-
33
-
-
0037002169
-
Phytochelatins and metallothioneins: Roles in heavy metal detoxification and homeostasis
-
Cobbett, C., and Goldsbrough, P. (2002) Phytochelatins and metallothioneins: roles in heavy metal detoxification and homeostasis. Annu. Rev. Plant Biol. 53, 159-182
-
(2002)
Annu. Rev. Plant Biol.
, vol.53
, pp. 159-182
-
-
Cobbett, C.1
Goldsbrough, P.2
-
34
-
-
0035144493
-
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
-
McCullough, K. D., Martindale, J. L., Klotz, L. O., Aw, T. Y., and Holbrook, N. J. (2001) Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol. Cell. Biol. 21, 1249-1259
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 1249-1259
-
-
McCullough, K.D.1
Martindale, J.L.2
Klotz, L.O.3
Aw, T.Y.4
Holbrook, N.J.5
-
35
-
-
1842843855
-
Roles of CHOP/GADD153 in endoplasmic reticulum stress
-
Oyadomari, S., and Mori, M. (2004) Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ. 11, 381-389
-
(2004)
Cell Death Differ.
, vol.11
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
36
-
-
0041382909
-
Long-living Ames dwarf mouse hepatocytes readily undergo apoptosis
-
Kennedy, M. A., Rakoczy, S. G., and Brown-Borg, H. M. (2003) Long-living Ames dwarf mouse hepatocytes readily undergo apoptosis. Exp. Gerontol. 38, 997-1008
-
(2003)
Exp. Gerontol.
, vol.38
, pp. 997-1008
-
-
Kennedy, M.A.1
Rakoczy, S.G.2
Brown-Borg, H.M.3
-
37
-
-
48249092267
-
Bcl-2 family members: Dual regulators of apoptosis and autophagy
-
Levine, B., Sinha, S., and Kroemer, G. (2008) Bcl-2 family members: dual regulators of apoptosis and autophagy. Autophagy 4, 600-606
-
(2008)
Autophagy
, vol.4
, pp. 600-606
-
-
Levine, B.1
Sinha, S.2
Kroemer, G.3
-
38
-
-
33745954330
-
BCL2 family in DNA damage and cell cycle control
-
Zinkel, S., Gross, A., and Yang, E. (2006) BCL2 family in DNA damage and cell cycle control. Cell Death Differ. 13, 1351-1359
-
(2006)
Cell Death Differ.
, vol.13
, pp. 1351-1359
-
-
Zinkel, S.1
Gross, A.2
Yang, E.3
-
39
-
-
0029899181
-
Molecular thanatopsis: A discourse on the BCL2 family and cell death
-
Yang, E., and Korsmeyer, S. J. (1996) Molecular thanatopsis: a discourse on the BCL2 family and cell death. Blood 88, 386-401
-
(1996)
Blood
, vol.88
, pp. 386-401
-
-
Yang, E.1
Korsmeyer, S.J.2
-
40
-
-
70349343443
-
The determination of aging rate by coordinated resistance to multiple forms of stress
-
(Guarente, L., Partridge, L., D. and Wallace, D. eds.), Cold Spring Harbor Press, Cold Spring, NY, USA
-
Lithgow, G. J., and Miller, R. A. (2008) The determination of aging rate by coordinated resistance to multiple forms of stress. In The Molecular Biology of Aging (Guarente, L., Partridge, L., D. and Wallace, D. eds.), Cold Spring Harbor Press, Cold Spring, NY, USA
-
(2008)
The Molecular Biology of Aging
-
-
Lithgow, G.J.1
Miller, R.A.2
-
41
-
-
0035098360
-
Microarray profiling of gene expression in aging and its alteration by caloric restriction in mice
-
Weindruch, R., Kayo, T., Lee, C. K., and Prolla, T. A. (2001) Microarray profiling of gene expression in aging and its alteration by caloric restriction in mice. J. Nutr. 131, 918S-923S
-
(2001)
J. Nutr.
, vol.131
-
-
Weindruch, R.1
Kayo, T.2
Lee, C.K.3
Prolla, T.A.4
-
42
-
-
0033610079
-
Gene expression profile of aging and its retardation by caloric restriction
-
Lee, C. K., Klopp, R. G., Weindruch, R., and Prolla, T. A. (1999) Gene expression profile of aging and its retardation by caloric restriction. Science 285, 1390-1393
-
(1999)
Science
, vol.285
, pp. 1390-1393
-
-
Lee, C.K.1
Klopp, R.G.2
Weindruch, R.3
Prolla, T.A.4
-
43
-
-
0031549576
-
Seminars in medicine of the Beth Israel Deaconess Medical Center. Caloric intake and aging
-
Weindruch, R., and Sohal, R. S. (1997) Seminars in medicine of the Beth Israel Deaconess Medical Center. Caloric intake and aging. N. Engl. J. Med. 337, 986-994
-
(1997)
N. Engl. J. Med.
, vol.337
, pp. 986-994
-
-
Weindruch, R.1
Sohal, R.S.2
-
44
-
-
0027512877
-
Low methionine ingestion by rats extends life span
-
Orentreich, N., Matias, J. R., DeFelice, A., and Zimmerman, J. A. (1993) Low methionine ingestion by rats extends life span. J. Nutr. 123, 269-274
-
(1993)
J. Nutr.
, vol.123
, pp. 269-274
-
-
Orentreich, N.1
Matias, J.R.2
DeFelice, A.3
Zimmerman, J.A.4
-
45
-
-
0034455827
-
Assessment of growth parameters and life span of GHR/BP gene-disrupted mice
-
Coschigano, K. T., Clemmons, D., Bellush, L. L., and Kopchick, J. J. (2000) Assessment of growth parameters and life span of GHR/BP gene-disrupted mice. Endocrinology 141, 2608-2613
-
(2000)
Endocrinology
, vol.141
, pp. 2608-2613
-
-
Coschigano, K.T.1
Clemmons, D.2
Bellush, L.L.3
Kopchick, J.J.4
-
46
-
-
64949116972
-
Cell stress and aging: New emphasis on multiplex resistance mechanisms
-
Miller, R. A. (2009) Cell stress and aging: new emphasis on multiplex resistance mechanisms. J. Gerontol. A Biol. Sci. Med. Sci. 64, 179-182
-
(2009)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.64
, pp. 179-182
-
-
Miller, R.A.1
-
47
-
-
0032972559
-
Positive correlation between mammalian life span and cellular resistance to stress
-
Kapahi, P., Boulton, M. E., and Kirkwood, T. B. (1999) Positive correlation between mammalian life span and cellular resistance to stress. Free Radic. Biol. Med. 26, 495-500
-
(1999)
Free Radic. Biol. Med.
, vol.26
, pp. 495-500
-
-
Kapahi, P.1
Boulton, M.E.2
Kirkwood, T.B.3
-
48
-
-
33745216272
-
Stress resistance and aging: Influence of genes and nutrition
-
Harper, J. M., Salmon, A. B., Chang, Y., Bonkowski, M., Bartke, A., and Miller, R. A. (2006) Stress resistance and aging: influence of genes and nutrition. Mech. Ageing Dev. 127, 687-694
-
(2006)
Mech. Ageing Dev.
, vol.127
, pp. 687-694
-
-
Harper, J.M.1
Salmon, A.B.2
Chang, Y.3
Bonkowski, M.4
Bartke, A.5
Miller, R.A.6
-
49
-
-
23844464540
-
Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance
-
Miller, R. A., Buehner, G., Chang, Y., Harper, J. M., Sigler, R., and Smith-Wheelock, M. (2005) Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance. Aging Cell 4, 119-125
-
(2005)
Aging Cell
, vol.4
, pp. 119-125
-
-
Miller, R.A.1
Buehner, G.2
Chang, Y.3
Harper, J.M.4
Sigler, R.5
Smith-Wheelock, M.6
-
50
-
-
45549096918
-
SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons
-
Li, Y., Xu, W., McBurney, M. W., and Longo, V. D. (2008) SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons. Cell. Metab. 8, 38-48
-
(2008)
Cell. Metab.
, vol.8
, pp. 38-48
-
-
Li, Y.1
Xu, W.2
McBurney, M.W.3
Longo, V.D.4
-
51
-
-
77953033838
-
5,7,3′-trihydroxy-3,4′-dimethoxyflavone-induced cell death in human Leukemia cells is dependent on caspases and activates the MAPK pathway
-
Torres, F., Quintana, J., and Estevez, F. (2010) 5,7,3′-trihydroxy- 3,4′-dimethoxyflavone-induced cell death in human Leukemia cells is dependent on caspases and activates the MAPK pathway. Mol. Carcinog. 49, 464-475
-
(2010)
Mol. Carcinog.
, vol.49
, pp. 464-475
-
-
Torres, F.1
Quintana, J.2
Estevez, F.3
-
52
-
-
33749370145
-
Differential tissue expression and activation of p38 MAPK alpha, beta, gamma, and delta isoforms in rheumatoid arthritis
-
Korb, A., Tohidast-Akrad, M., Cetin, E., Axmann, R., Smolen, J., and Schett, G. (2006) Differential tissue expression and activation of p38 MAPK alpha, beta, gamma, and delta isoforms in rheumatoid arthritis. Arthritis Rheum. 54, 2745-2756
-
(2006)
Arthritis Rheum.
, vol.54
, pp. 2745-2756
-
-
Korb, A.1
Tohidast-Akrad, M.2
Cetin, E.3
Axmann, R.4
Smolen, J.5
Schett, G.6
-
53
-
-
0035895803
-
SB 239063, a novel p38 inhibitor, attenuates early neuronal injury following ischemia
-
Legos, J. J., Erhardt, J. A., White, R. F., Lenhard, S. C., Chandra, S., Parsons, A. A., Tuma, R. F., and Barone, F. C. (2001) SB 239063, a novel p38 inhibitor, attenuates early neuronal injury following ischemia. Brain Res. 892, 70-77
-
(2001)
Brain Res.
, vol.892
, pp. 70-77
-
-
Legos, J.J.1
Erhardt, J.A.2
White, R.F.3
Lenhard, S.C.4
Chandra, S.5
Parsons, A.A.6
Tuma, R.F.7
Barone, F.C.8
-
54
-
-
77449099066
-
P38 MAP kinase in valve interstitial cells is activated by angiotensin II or nitric oxide/peroxynitrite, but reduced by Toll-like receptor-2 stimulation
-
Rabkin, S. W., Lodhia, P., and Luong, M. W. (2009) P38 MAP kinase in valve interstitial cells is activated by angiotensin II or nitric oxide/peroxynitrite, but reduced by Toll-like receptor-2 stimulation. J. Heart Valve Dis. 18, 653-661
-
(2009)
J. Heart Valve Dis.
, vol.18
, pp. 653-661
-
-
Rabkin, S.W.1
Lodhia, P.2
Luong, M.W.3
-
55
-
-
0024281381
-
A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization
-
Sukhatme, V. P., Cao, X. M., Chang, L. C., Tsai-Morris, C. H., Stamenkovich, D., Ferreira, P. C., Cohen, D. R., Edwards, S. A., Shows, T. B., Curran, T., Le Beau, M. M., and Adamson, E. D. (1988) A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization. Cell 53, 37-43
-
(1988)
Cell
, vol.53
, pp. 37-43
-
-
Sukhatme, V.P.1
Cao, X.M.2
Chang, L.C.3
Tsai-Morris, C.H.4
Stamenkovich, D.5
Ferreira, P.C.6
Cohen, D.R.7
Edwards, S.A.8
Shows, T.B.9
Curran, T.10
Le Beau, M.M.11
Adamson, E.D.12
-
56
-
-
0036270508
-
Egr1 transcription factor: Multiple roles in prostate tumor cell growth and survival
-
Adamson, E. D., and Mercola, D. (2002) Egr1 transcription factor: multiple roles in prostate tumor cell growth and survival. Tumour Biol. 23, 93-102
-
(2002)
Tumour Biol.
, vol.23
, pp. 93-102
-
-
Adamson, E.D.1
Mercola, D.2
-
57
-
-
33847050801
-
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
-
Kensler, T. W., Wakabayashi, N., and Biswal, S. (2007) Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu. Rev. Pharmacol. Toxicol. 47, 89-116
-
(2007)
Annu. Rev. Pharmacol. Toxicol.
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
Wakabayashi, N.2
Biswal, S.3
-
58
-
-
67649402187
-
The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress
-
Nguyen, T., Nioi, P., and Pickett, C. B. (2009) The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress. J. Biol. Chem. 284, 13291-13295
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 13291-13295
-
-
Nguyen, T.1
Nioi, P.2
Pickett, C.B.3
-
59
-
-
0142166328
-
Cancer chemoprevention with dietary phytochemicals
-
Surh, Y. J. (2003) Cancer chemoprevention with dietary phytochemicals. Nat. Rev. Cancer 3, 768-780
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 768-780
-
-
Surh, Y.J.1
-
60
-
-
85047693348
-
Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta
-
Garofalo, R. S., Orena, S. J., Rafidi, K., Torchia, A. J., Stock, J. L., Hildebrandt, A. L., Coskran, T., Black, S. C., Brees, D. J., Wicks, J. R., McNeish, J. D., and Coleman, K. G. (2003) Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta. J. Clin. Invest. 112, 197-208
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 197-208
-
-
Garofalo, R.S.1
Orena, S.J.2
Rafidi, K.3
Torchia, A.J.4
Stock, J.L.5
Hildebrandt, A.L.6
Coskran, T.7
Black, S.C.8
Brees, D.J.9
Wicks, J.R.10
McNeish, J.D.11
Coleman, K.G.12
-
61
-
-
40849118472
-
Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans
-
Tullet, J. M., Hertweck, M., An, J. H., Baker, J., Hwang, J. Y., Liu, S., Oliveira, R. P., Baumeister, R., and Blackwell, T. K. (2008) Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans. Cell 132, 1025-1038
-
(2008)
Cell
, vol.132
, pp. 1025-1038
-
-
Tullet, J.M.1
Hertweck, M.2
An, J.H.3
Baker, J.4
Hwang, J.Y.5
Liu, S.6
Oliveira, R.P.7
Baumeister, R.8
Blackwell, T.K.9
-
62
-
-
34249891333
-
Two neurons mediate diet-restriction-induced longevity in C. elegans
-
Bishop, N. A., and Guarente, L. (2007) Two neurons mediate diet-restriction-induced longevity in C. elegans. Nature 447, 545-549
-
(2007)
Nature
, vol.447
, pp. 545-549
-
-
Bishop, N.A.1
Guarente, L.2
-
63
-
-
37749024370
-
Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila
-
Sykiotis, G. P., and Bohmann, D. (2008) Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila. Dev. Cell 14, 76-85
-
(2008)
Dev. Cell
, vol.14
, pp. 76-85
-
-
Sykiotis, G.P.1
Bohmann, D.2
-
64
-
-
40649108843
-
Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction
-
Pearson, K. J., Lewis, K. N., Price, N. L., Chang, J. W., Perez, E., Cascajo, M. V., Tamashiro, K. L., Poosala, S., Csiszar, A., Ungvari, Z., Kensler, T. W., Yamamoto, M., Egan, J. M., Longo, D. L., Ingram, D. K., Navas, P., and de Cabo, R. (2008) Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction. Proc. Natl. Acad. Sci. U. S. A. 105, 2325-2330
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 2325-2330
-
-
Pearson, K.J.1
Lewis, K.N.2
Price, N.L.3
Chang, J.W.4
Perez, E.5
Cascajo, M.V.6
Tamashiro, K.L.7
Poosala, S.8
Csiszar, A.9
Ungvari, Z.10
Kensler, T.W.11
Yamamoto, M.12
Egan, J.M.13
Longo, D.L.14
Ingram, D.K.15
Navas, P.16
De Cabo, R.17
-
65
-
-
2342627368
-
Elevated gadd153/chop expression and enhanced c-Jun N-terminal protein kinase activation sensitizes aged cells to ER stress
-
Li, J., and Holbrook, N. J. (2004) Elevated gadd153/chop expression and enhanced c-Jun N-terminal protein kinase activation sensitizes aged cells to ER stress. Exp. Gerontol. 39, 735-744
-
(2004)
Exp. Gerontol.
, vol.39
, pp. 735-744
-
-
Li, J.1
Holbrook, N.J.2
-
66
-
-
55849096988
-
Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes
-
Song, B., Scheuner, D., Ron, D., Pennathur, S., and Kaufman, R. J. (2008) Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes. J. Clin. Invest. 118, 3378-3389
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3378-3389
-
-
Song, B.1
Scheuner, D.2
Ron, D.3
Pennathur, S.4
Kaufman, R.J.5
-
67
-
-
33745222805
-
Is (your cellular response to) stress killing you?
-
Sierra, F. (2006) Is (your cellular response to) stress killing you? J. Gerontol. A Biol. Sci. Med. Sci. 61, 557-561
-
(2006)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.61
, pp. 557-561
-
-
Sierra, F.1
-
68
-
-
13844298645
-
Gene expression profile of long-lived Ames dwarf mice and Little mice
-
Amador-Noguez, D., Yagi, K., Venable, S., and Darlington, G. (2004) Gene expression profile of long-lived Ames dwarf mice and Little mice. Aging Cell 3, 423-441
-
(2004)
Aging Cell
, vol.3
, pp. 423-441
-
-
Amador-Noguez, D.1
Yagi, K.2
Venable, S.3
Darlington, G.4
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