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Volumn 292, Issue 5, 2007, Pages

Adiposity profile in the dwarf rat: An unusually lean model of profound growth hormone deficiency

Author keywords

Adipose tissue; Bone marrow fat; Dwarfism; Leptin

Indexed keywords

GROWTH HORMONE; GROWTH HORMONE RECEPTOR; LEPTIN; SOMATOMEDIN C;

EID: 34247552777     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00417.2006     Document Type: Article
Times cited : (25)

References (39)
  • 1
    • 0020030961 scopus 로고
    • Corticoliberin and somatoliberin activity in the pituitary stalk median eminence of rats after neonatal treatment with monosodium glutamate
    • Acs Z, Antoni FA, Makara GB. Corticoliberin and somatoliberin activity in the pituitary stalk median eminence of rats after neonatal treatment with monosodium glutamate. J Endocrinol 93: 239-245, 1982.
    • (1982) J Endocrinol , vol.93 , pp. 239-245
    • Acs, Z.1    Antoni, F.A.2    Makara, G.B.3
  • 5
    • 0021183450 scopus 로고
    • Specific depletion of immunoreactive growth hormone-releasing factor by monosodium glutamate in rat median eminence
    • Bloch B, Ling N, Benoit R, Wehrenberg WB, Guillemin R. Specific depletion of immunoreactive growth hormone-releasing factor by monosodium glutamate in rat median eminence. Nature 307: 272-273, 1984.
    • (1984) Nature , vol.307 , pp. 272-273
    • Bloch, B.1    Ling, N.2    Benoit, R.3    Wehrenberg, W.B.4    Guillemin, R.5
  • 6
    • 0016891181 scopus 로고
    • The induction of obesity in rodents by means of monosodium glutamate
    • Bunyan J, Murrell EA, Shah PP. The induction of obesity in rodents by means of monosodium glutamate. Br J Nutr 35: 25-39, 1976.
    • (1976) Br J Nutr , vol.35 , pp. 25-39
    • Bunyan, J.1    Murrell, E.A.2    Shah, P.P.3
  • 9
    • 0026377007 scopus 로고
    • Glycine 119 of bovine growth hormone is critical for growth-promoting activity
    • Chen WY, Wight DC, Mehta BV, Wagner TE, Kopchick JJ. Glycine 119 of bovine growth hormone is critical for growth-promoting activity. Mol Endocrinol 5: 1845-1852, 1991.
    • (1991) Mol Endocrinol , vol.5 , pp. 1845-1852
    • Chen, W.Y.1    Wight, D.C.2    Mehta, B.V.3    Wagner, T.E.4    Kopchick, J.J.5
  • 10
    • 0029923352 scopus 로고    scopus 로고
    • The obese growth hormone (GH)-deficient dwarf rat: Body fat responses to patterned delivery of GH and insulin-like growth factor-I
    • Clark RG, Mortensen DL, Carlsson LM, Carlsson B, Carmignac D, Robinson IC. The obese growth hormone (GH)-deficient dwarf rat: body fat responses to patterned delivery of GH and insulin-like growth factor-I. Endocrinology 137: 1904-1912, 1996.
    • (1996) Endocrinology , vol.137 , pp. 1904-1912
    • Clark, R.G.1    Mortensen, D.L.2    Carlsson, L.M.3    Carlsson, B.4    Carmignac, D.5    Robinson, I.C.6
  • 11
    • 0041419437 scopus 로고    scopus 로고
    • Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span
    • Coschigano KT, Holland AN, Riders ME, List EO, Flyvbjerg A, Kopchick JJ. Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span. Endocrinology 144: 3799-3810, 2003.
    • (2003) Endocrinology , vol.144 , pp. 3799-3810
    • Coschigano, K.T.1    Holland, A.N.2    Riders, M.E.3    List, E.O.4    Flyvbjerg, A.5    Kopchick, J.J.6
  • 12
    • 0038121116 scopus 로고    scopus 로고
    • Growth hormone therapy in adults
    • Cummings DE, Merriam GR. Growth hormone therapy in adults. Annu Rev Med 54: 513-533, 2003.
    • (2003) Annu Rev Med , vol.54 , pp. 513-533
    • Cummings, D.E.1    Merriam, G.R.2
  • 13
    • 33748434596 scopus 로고    scopus 로고
    • Hypothalamic expression of human growth hormone induces post-pubertal hypergonadotrophism in male transgenic growth retarded (Tgr) rats
    • Davies JS, Thompson NM, Christian HC, Pinilla L, Ebling FJ, Tena-Sempere M, Wells T. Hypothalamic expression of human growth hormone induces post-pubertal hypergonadotrophism in male transgenic growth retarded (Tgr) rats. J Neuroendocrinol 18: 719-731, 2006.
    • (2006) J Neuroendocrinol , vol.18 , pp. 719-731
    • Davies, J.S.1    Thompson, N.M.2    Christian, H.C.3    Pinilla, L.4    Ebling, F.J.5    Tena-Sempere, M.6    Wells, T.7
  • 14
    • 0027455584 scopus 로고
    • Growth hormone deficiency in "little" mice results in aberrant body composition, reduced insulin-like growth factor-I and insulin-like growth factor-binding protein-3 (IGFBP-3) but does not affect IGFBP-2, -1 or -4
    • Donahue LR, Beamer WG. Growth hormone deficiency in "little" mice results in aberrant body composition, reduced insulin-like growth factor-I and insulin-like growth factor-binding protein-3 (IGFBP-3) but does not affect IGFBP-2, -1 or -4. J Endocrinol 136: 91-104, 1993.
    • (1993) J Endocrinol , vol.136 , pp. 91-104
    • Donahue, L.R.1    Beamer, W.G.2
  • 17
    • 0029783602 scopus 로고    scopus 로고
    • Dominant dwarfism in transgenic rats by targeting human growth hormone (GH) to hypothalamic GH-releasing factor neurons
    • Flavell DM, Wells T, Wells SE, Carmignac DF, Thomas GB, Robinson IC. Dominant dwarfism in transgenic rats by targeting human growth hormone (GH) to hypothalamic GH-releasing factor neurons. EMBO J 15: 3871-3879, 1996.
    • (1996) EMBO J , vol.15 , pp. 3871-3879
    • Flavell, D.M.1    Wells, T.2    Wells, S.E.3    Carmignac, D.F.4    Thomas, G.B.5    Robinson, I.C.6
  • 18
    • 33751044208 scopus 로고    scopus 로고
    • Developmental aspects of adipose tissue in GH-receptor and prolactin receptor gene disrupted mice: Site-specific effects upon proliferation, differentiation and hormone sensitivity
    • Flint DJ, Binart N, Boumard S, Kopchick JJ, Kelly P. Developmental aspects of adipose tissue in GH-receptor and prolactin receptor gene disrupted mice: site-specific effects upon proliferation, differentiation and hormone sensitivity. J Endocrinol 191: 101-111, 2006.
    • (2006) J Endocrinol , vol.191 , pp. 101-111
    • Flint, D.J.1    Binart, N.2    Boumard, S.3    Kopchick, J.J.4    Kelly, P.5
  • 19
    • 0027301824 scopus 로고
    • Influence of growth hormone deficiency on growth, and body composition in rats: Site-specific effects upon adipose tissue development
    • Flint DJ, Gardner MJ. Influence of growth hormone deficiency on growth, and body composition in rats: site-specific effects upon adipose tissue development. J Endocrinol 137: 203-213, 1993.
    • (1993) J Endocrinol , vol.137 , pp. 203-213
    • Flint, D.J.1    Gardner, M.J.2
  • 20
    • 34247576564 scopus 로고    scopus 로고
    • Gevers EF, Loveridge N, Robinson IC. Bone marrow adipocytes: a neglected target tissue for growth hormone. 1st Joint Symposium of the Growth Hormone and IGF Societies, Boston, MA. Growth Horm IGF Res 12: 249 (Abstract 077), 2002.
    • Gevers EF, Loveridge N, Robinson IC. Bone marrow adipocytes: a neglected target tissue for growth hormone. 1st Joint Symposium of the Growth Hormone and IGF Societies, Boston, MA. Growth Horm IGF Res 12: 249 (Abstract 077), 2002.
  • 21
    • 0036772984 scopus 로고    scopus 로고
    • Bone marrow adipocytes: A neglected target tissue for growth hormone
    • Gevers EF, Loveridge N, Robinson IC. Bone marrow adipocytes: a neglected target tissue for growth hormone. Endocrinology 143: 4065-4073, 2002.
    • (2002) Endocrinology , vol.143 , pp. 4065-4073
    • Gevers, E.F.1    Loveridge, N.2    Robinson, I.C.3
  • 22
    • 0032230286 scopus 로고    scopus 로고
    • Characterisation of the inhibitory effect of growth hormone on primary preadipocyte differentiation
    • Hansen LH, Madsen B, Teisner B, Nielsen JH, Billestrup N. Characterisation of the inhibitory effect of growth hormone on primary preadipocyte differentiation. Mol Endocrinol 12: 1140-1149, 1998.
    • (1998) Mol Endocrinol , vol.12 , pp. 1140-1149
    • Hansen, L.H.1    Madsen, B.2    Teisner, B.3    Nielsen, J.H.4    Billestrup, N.5
  • 23
    • 26844546713 scopus 로고    scopus 로고
    • The intermediate lactotroph: A morphologically distinct, ghrelin-responsive pituitary cell in the dwarf (dw/dw) rat
    • Heurta-Ocampo I, Christian H, Thompson NM, El-Kasti MM, Wells T. The intermediate lactotroph: a morphologically distinct, ghrelin-responsive pituitary cell in the dwarf (dw/dw) rat. Endocrinology 146: 5012-5023, 2005.
    • (2005) Endocrinology , vol.146 , pp. 5012-5023
    • Heurta-Ocampo, I.1    Christian, H.2    Thompson, N.M.3    El-Kasti, M.M.4    Wells, T.5
  • 25
    • 0028537612 scopus 로고
    • Growth patterns and body composition of transgenic mice expressing mutated bovine somatotropin genes
    • Knapp JR, Chen WY, Turner ND, Byers FM, Kopchick JJ. Growth patterns and body composition of transgenic mice expressing mutated bovine somatotropin genes. J Anim Sci 72: 2812-2819, 1994.
    • (1994) J Anim Sci , vol.72 , pp. 2812-2819
    • Knapp, J.R.1    Chen, W.Y.2    Turner, N.D.3    Byers, F.M.4    Kopchick, J.J.5
  • 27
    • 0026575194 scopus 로고
    • Hepatic steroid hydroxylating enzymes are controlled by the sexually dimorphic pattern of growth hormone secretion in normal and dwarf rats
    • Legraverend C, Mode A, Wells T, Robinson IC, Gustafsson JÅ. Hepatic steroid hydroxylating enzymes are controlled by the sexually dimorphic pattern of growth hormone secretion in normal and dwarf rats. FASEB J 6: 711-718, 1992.
    • (1992) FASEB J , vol.6 , pp. 711-718
    • Legraverend, C.1    Mode, A.2    Wells, T.3    Robinson, I.C.4    Gustafsson, J.5
  • 28
    • 0002864903 scopus 로고
    • Some histological methods. Trichrome stainings and their preliminary technique
    • Masson P. Some histological methods. Trichrome stainings and their preliminary technique. Bull Int Assoc Med 12: 75, 1929.
    • (1929) Bull Int Assoc Med , vol.12 , pp. 75
    • Masson, P.1
  • 29
    • 0018241231 scopus 로고
    • Models of neuroendocrine regulation: Use of monosodium glutamate as an investigational tool
    • Nemeroff CB, Lipton MA, Kizer JS. Models of neuroendocrine regulation: use of monosodium glutamate as an investigational tool. Dev Neurosci 1: 102-109, 1978.
    • (1978) Dev Neurosci , vol.1 , pp. 102-109
    • Nemeroff, C.B.1    Lipton, M.A.2    Kizer, J.S.3
  • 30
    • 33748471379 scopus 로고    scopus 로고
    • Growth hormone receptor gene deficiency causes delayed insulin responsiveness in skeletal muscles without affecting compensatory islet cell overgrowth in obese mice
    • Robertson K, Kopchick JJ, Liu JL. Growth hormone receptor gene deficiency causes delayed insulin responsiveness in skeletal muscles without affecting compensatory islet cell overgrowth in obese mice. Am J Physiol Endocrinol Metab 291: E491-E498, 2006.
    • (2006) Am J Physiol Endocrinol Metab , vol.291
    • Robertson, K.1    Kopchick, J.J.2    Liu, J.L.3
  • 31
    • 0043231590 scopus 로고    scopus 로고
    • Effects of growth hormone administration in human obesity
    • Shadid S, Jensen MD. Effects of growth hormone administration in human obesity. Obes Res 11: 170-175, 2003.
    • (2003) Obes Res , vol.11 , pp. 170-175
    • Shadid, S.1    Jensen, M.D.2
  • 32
    • 0346849704 scopus 로고    scopus 로고
    • Constitutively active signal transducer and activator of transcription 5 can replace the requirement for growth hormone in adipogenesis of 3T3-F442A preadipocytes
    • Shang CA, Waters MJ. Constitutively active signal transducer and activator of transcription 5 can replace the requirement for growth hormone in adipogenesis of 3T3-F442A preadipocytes. Mol Endocrinol 17: 2494-2508, 2003.
    • (2003) Mol Endocrinol , vol.17 , pp. 2494-2508
    • Shang, C.A.1    Waters, M.J.2
  • 33
    • 34247618622 scopus 로고    scopus 로고
    • Stevenson AE, Davies JS, Coschigano KT, Kopchick JJ, Wells T. Adiposity profiles in rodent models of profound and moderate GH deficiency (Abstract P3-97). Proceedings of the 87th Annual Meeting of the Endocrine Society, San Diego, CA, 2005.
    • Stevenson AE, Davies JS, Coschigano KT, Kopchick JJ, Wells T. Adiposity profiles in rodent models of profound and moderate GH deficiency (Abstract P3-97). Proceedings of the 87th Annual Meeting of the Endocrine Society, San Diego, CA, 2005.
  • 34
    • 1042275336 scopus 로고    scopus 로고
    • Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in-vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor
    • Thompson NM, Gill DA, Davies R, Loveridge N, Houston PA, Robinson IC, Wells T. Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in-vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor. Endocrinology 145: 234-242, 2004.
    • (2004) Endocrinology , vol.145 , pp. 234-242
    • Thompson, N.M.1    Gill, D.A.2    Davies, R.3    Loveridge, N.4    Houston, P.A.5    Robinson, I.C.6    Wells, T.7
  • 37
    • 0030228123 scopus 로고    scopus 로고
    • Growth hormone treatment of hypophysectomised rats increases catecholamine induced lipolysis and the number of beta-adrenergic receptors in adipocytes: No differences in the effects of growth hormone on different fat depots
    • Yang S, Bjorntorp P, Liu X, Eden S. Growth hormone treatment of hypophysectomised rats increases catecholamine induced lipolysis and the number of beta-adrenergic receptors in adipocytes: no differences in the effects of growth hormone on different fat depots. Obes Res 4: 471-478, 1996.
    • (1996) Obes Res , vol.4 , pp. 471-478
    • Yang, S.1    Bjorntorp, P.2    Liu, X.3    Eden, S.4
  • 38
    • 0033605570 scopus 로고    scopus 로고
    • Growth hormone-dependent differentiation of 3T3-F442A preadipocytes requires Janus kinase/signal transducer and activator of transcription but not mitogen-activated protein kinase or p70 S6 kinase signalling
    • Yarwood SJ, Sale EM, Sale GJ, Houslay MD, Kilgour E, Anderson NG. Growth hormone-dependent differentiation of 3T3-F442A preadipocytes requires Janus kinase/signal transducer and activator of transcription but not mitogen-activated protein kinase or p70 S6 kinase signalling. J Biol Chem 274: 8662-8668, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 8662-8668
    • Yarwood, S.J.1    Sale, E.M.2    Sale, G.J.3    Houslay, M.D.4    Kilgour, E.5    Anderson, N.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.