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Volumn 60, Issue SUPPL. 3, 2003, Pages 103-112

History and future of growth hormone research

Author keywords

Functional genomics; Gene disrupted mice; Genomics; Growth hormone; Growth hormone antagonists; Growth hormone receptor; Proteomics; Transgenic mice

Indexed keywords

AMINO ACID DERIVATIVE; DOPAMINE RECEPTOR STIMULATING AGENT; GROWTH HORMONE; GROWTH HORMONE ANTAGONIST; GROWTH HORMONE RECEPTOR; HORMONE ANTAGONIST; PEGVISOMANT; SOMATOMEDIN C; SOMATOSTATIN; UNCLASSIFIED DRUG;

EID: 0348010586     PISSN: 03010163     EISSN: None     Source Type: Journal    
DOI: 10.1159/000074510     Document Type: Conference Paper
Times cited : (25)

References (68)
  • 1
    • 0001854965 scopus 로고
    • The effect of the anterior lobe administered intraperitoneally upon growth, maturity and oestrus cycles of the rat
    • Evans HM, Long JA: The effect of the anterior lobe administered intraperitoneally upon growth, maturity and oestrus cycles of the rat. Anat Rec 1921;21:62-63.
    • (1921) Anat Rec , vol.21 , pp. 62-63
    • Evans, H.M.1    Long, J.A.2
  • 2
    • 37049224476 scopus 로고
    • The isolation of pituitary growth hormone
    • Li CH, Evans HM: The isolation of pituitary growth hormone. Science 1944;99:183-184.
    • (1944) Science , vol.99 , pp. 183-184
    • Li, C.H.1    Evans, H.M.2
  • 3
    • 0018776478 scopus 로고
    • Human growth hormone: Complementary DNA cloning and expression in bacteria
    • Martial JA, Hallewell RA, Baxter JD, Goodman HM: Human growth hormone: Complementary DNA cloning and expression in bacteria. Science 1979;205:602-607.
    • (1979) Science , vol.205 , pp. 602-607
    • Martial, J.A.1    Hallewell, R.A.2    Baxter, J.D.3    Goodman, H.M.4
  • 6
    • 0025322555 scopus 로고
    • Expression of a mutated bovine growth hormone gene suppresses growth of transgenic mice
    • Chen WY, Wight DC, Wagner TE, Kopchick JJ: Expression of a mutated bovine growth hormone gene suppresses growth of transgenic mice. Proc Natl Acad Sci USA 1990;87:5061-5065.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5061-5065
    • Chen, W.Y.1    Wight, D.C.2    Wagner, T.E.3    Kopchick, J.J.4
  • 7
    • 0026598960 scopus 로고
    • Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex
    • de Vos AM, Ultsch M, Kossiakoff AA: Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex. Science 1992;255:306-312.
    • (1992) Science , vol.255 , pp. 306-312
    • De Vos, A.M.1    Ultsch, M.2    Kossiakoff, A.A.3
  • 8
    • 0031622702 scopus 로고    scopus 로고
    • Signaling via JAK tyrosine kinases: Growth hormone receptor as a model system
    • Carter-Su C, Smit LS: Signaling via JAK tyrosine kinases: Growth hormone receptor as a model system. Recent Prog Horm Res 1998;53:61-82.
    • (1998) Recent Prog Horm Res , vol.53 , pp. 61-82
    • Carter-Su, C.1    Smit, L.S.2
  • 9
    • 0026048419 scopus 로고
    • Functional antagonism between endogenous mouse growth hormone (GH) and a GH analog results in dwarf transgenic mice
    • Chen WY, White ME, Wagner TE, Kopchick JJ: Functional antagonism between endogenous mouse growth hormone (GH) and a GH analog results in dwarf transgenic mice. Endocrinology 1991;129:1402-1408.
    • (1991) Endocrinology , vol.129 , pp. 1402-1408
    • Chen, W.Y.1    White, M.E.2    Wagner, T.E.3    Kopchick, J.J.4
  • 10
    • 0026377007 scopus 로고
    • Glycine 119 of bovine growth hormone is critical for growth-promoting activity
    • Chen WY, Wight DC, Mehta BV, Wagner TE, Kopchick JJ: Glycine 119 of bovine growth hormone is critical for growth-promoting activity. Mol Endocrinol 1991;5:1845-1852.
    • (1991) Mol Endocrinol , vol.5 , pp. 1845-1852
    • Chen, W.Y.1    Wight, D.C.2    Mehta, B.V.3    Wagner, T.E.4    Kopchick, J.J.5
  • 11
    • 0026533044 scopus 로고
    • A growth hormone (GH) analog can antagonize the ability of native GH to promote differentiation of 3T3-F442A preadipocytes and stimulate insulin-like and lipolytic activities in primary rat adipocytes
    • Okada S, Chen WY, Wiehl P, Kelder B, Goodman HM, Guller S, Sonenberg M, Kopchick JJ: A growth hormone (GH) analog can antagonize the ability of native GH to promote differentiation of 3T3-F442A preadipocytes and stimulate insulin-like and lipolytic activities in primary rat adipocytes. Endocrinology 1992;130:2284-2290.
    • (1992) Endocrinology , vol.130 , pp. 2284-2290
    • Okada, S.1    Chen, W.Y.2    Wiehl, P.3    Kelder, B.4    Goodman, H.M.5    Guller, S.6    Sonenberg, M.7    Kopchick, J.J.8
  • 13
    • 0032731982 scopus 로고    scopus 로고
    • Is the Laron mouse an accurate model of Laron syndrome?
    • Kopchick JJ, Laron Z: Is the Laron mouse an accurate model of Laron syndrome? Mol Genet Metab 1999;68:232-236.
    • (1999) Mol Genet Metab , vol.68 , pp. 232-236
    • Kopchick, J.J.1    Laron, Z.2
  • 14
    • 0035376370 scopus 로고    scopus 로고
    • Growth hormone receptor antagonists: Discovery and potential uses
    • Kopchick JJ, Okada S: Growth hormone receptor antagonists: Discovery and potential uses. Growth Horm IGF Res 2001;11(suppl A):S103-S109.
    • (2001) Growth Horm IGF Res , vol.11 , Issue.SUPPL. A
    • Kopchick, J.J.1    Okada, S.2
  • 15
    • 0020729431 scopus 로고
    • Structure and evolution of the growth hormone gene family
    • Miller WL, Eberhardt NL: Structure and evolution of the growth hormone gene family. Endocr Rev 1983;4:97-130.
    • (1983) Endocr Rev , vol.4 , pp. 97-130
    • Miller, W.L.1    Eberhardt, N.L.2
  • 16
    • 0023038571 scopus 로고
    • Isolation of a novel prolactin-like cDNA clone from developing rat placenta
    • Duckworth ML, Peden LM, Friesen HG: Isolation of a novel prolactin-like cDNA clone from developing rat placenta. J Biol Chem 1986;261:10879-10884.
    • (1986) J Biol Chem , vol.261 , pp. 10879-10884
    • Duckworth, M.L.1    Peden, L.M.2    Friesen, H.G.3
  • 18
    • 0021209672 scopus 로고
    • Nucleotide sequence of a growth-related mRNA encoding a member of the prolactin-growth hormone family
    • Linzer DI, Nathans D: Nucleotide sequence of a growth-related mRNA encoding a member of the prolactin-growth hormone family. Proc Natl Acad Sci USA 1984;81:4255-4259.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 4255-4259
    • Linzer, D.I.1    Nathans, D.2
  • 20
    • 0027499692 scopus 로고
    • Decidual prolactin-related protein. Identification, molecular cloning, and characterization
    • Roby KF, Deb S, Gibori G, Szpirer C, Levan G, Kwok SC, Soares MJ: Decidual prolactin-related protein. Identification, molecular cloning, and characterization. J Biol Chem 1993;268:3136-3142.
    • (1993) J Biol Chem , vol.268 , pp. 3136-3142
    • Roby, K.F.1    Deb, S.2    Gibori, G.3    Szpirer, C.4    Levan, G.5    Kwok, S.C.6    Soares, M.J.7
  • 21
    • 0029825056 scopus 로고    scopus 로고
    • Sequence-function relationships within the expanding family of prolactin, growth hormone, placental lactogen, and related proteins in mammals
    • Goffin V, Shiverick KT, Kelly PA, Martial JA: Sequence-function relationships within the expanding family of prolactin, growth hormone, placental lactogen, and related proteins in mammals. Endocr Rev 1996;17:385-410.
    • (1996) Endocr Rev , vol.17 , pp. 385-410
    • Goffin, V.1    Shiverick, K.T.2    Kelly, P.A.3    Martial, J.A.4
  • 22
    • 0017894256 scopus 로고
    • Recombination of the biologically active peptides from a tryptic digest of bovine growth hormone
    • Hara K, Hsu Chen CJ, Sonenberg M: Recombination of the biologically active peptides from a tryptic digest of bovine growth hormone. Biochemistry 1978;17:550-556.
    • (1978) Biochemistry , vol.17 , pp. 550-556
    • Hara, K.1    Hsu Chen, C.J.2    Sonenberg, M.3
  • 23
    • 0021034733 scopus 로고
    • Design of a peptide hormone: Synthesis and characterization of a model peptide with calcitonin-like activity
    • Moe GR, Miller RJ, Kaiser ET: Design of a peptide hormone: Synthesis and characterization of a model peptide with calcitonin-like activity. J Am Chem Soc 1983;105:4100-4102.
    • (1983) J Am Chem Soc , vol.105 , pp. 4100-4102
    • Moe, G.R.1    Miller, R.J.2    Kaiser, E.T.3
  • 24
    • 0022253778 scopus 로고
    • Design, synthesis, and characterization of a model peptide having potent calcitonin-like biological activity: Implications for calcitonin structure/activity
    • Moe GR, Kaiser ET: Design, synthesis, and characterization of a model peptide having potent calcitonin-like biological activity: Implications for calcitonin structure/activity. Biochemistry 1985;24:1971-1976.
    • (1985) Biochemistry , vol.24 , pp. 1971-1976
    • Moe, G.R.1    Kaiser, E.T.2
  • 25
    • 0027163131 scopus 로고
    • A growth hormone (GH) analog that antagonizes the lipolytic effect but retains full insulin-like (antilipolytic) activity of GH
    • Campbell RM, Chen WY, Wiehl P, Kelder B, Kopchick JJ, Scanes CG: A growth hormone (GH) analog that antagonizes the lipolytic effect but retains full insulin-like (antilipolytic) activity of GH. Proc Soc Exp Biol Med 1993;203:311-316.
    • (1993) Proc Soc Exp Biol Med , vol.203 , pp. 311-316
    • Campbell, R.M.1    Chen, W.Y.2    Wiehl, P.3    Kelder, B.4    Kopchick, J.J.5    Scanes, C.G.6
  • 26
    • 0028357212 scopus 로고
    • In vitro and in vivo studies of the antagonistic effects of human growth hormone analogs
    • Chen WY, Chen N, Yun J, Wagner TE, Kopchick JJ: In vitro and in vivo studies of the antagonistic effects of human growth hormone analogs. J Biol Chem 1994;269:15892-15897.
    • (1994) J Biol Chem , vol.269 , pp. 15892-15897
    • Chen, W.Y.1    Chen, N.2    Yun, J.3    Wagner, T.E.4    Kopchick, J.J.5
  • 27
    • 24544455241 scopus 로고
    • Effects of growth hormone antagonist (hGH-G120R) on 3T3-F442A adipocytes
    • Okada S, Kopchick JJ: Effects of growth hormone antagonist (hGH-G120R) on 3T3-F442A adipocytes; in: Diabetes 1995;135A:44.
    • (1995) Diabetes , vol.135 A , pp. 44
    • Okada, S.1    Kopchick, J.J.2
  • 29
    • 0345883100 scopus 로고    scopus 로고
    • Mini mice, football and dirty shorts
    • Kopchick JJ: Mini mice, football and dirty shorts. Endocrinologist 2001;61:13.
    • (2001) Endocrinologist , vol.61 , pp. 13
    • Kopchick, J.J.1
  • 31
    • 0036800303 scopus 로고    scopus 로고
    • Growth hormone receptor antagonists: Discovery, development, and use in patients with acromegaly
    • Kopchick JJ, Parkinson C, Stevens EC, Trainer PJ: Growth hormone receptor antagonists: Discovery, development, and use in patients with acromegaly. Endocr Rev 2002;23:623-646.
    • (2002) Endocr Rev , vol.23 , pp. 623-646
    • Kopchick, J.J.1    Parkinson, C.2    Stevens, E.C.3    Trainer, P.J.4
  • 33
    • 85047684868 scopus 로고    scopus 로고
    • Control of tumor size and disease activity during co-treatment with octreotide and the growth hormone receptor antagonist pegvisomant in an acromegalic patient
    • van der Lely AJ, Muller A, Janssen JA, Davis RJ, Zib KA, Scarlett JA, Lamberts SW: Control of tumor size and disease activity during co-treatment with octreotide and the growth hormone receptor antagonist pegvisomant in an acromegalic patient. J Clin Endocrinol Metab 2001;86:478-481.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 478-481
    • Van Der Lely, A.J.1    Muller, A.2    Janssen, J.A.3    Davis, R.J.4    Zib, K.A.5    Scarlett, J.A.6    Lamberts, S.W.7
  • 35
    • 0029843379 scopus 로고    scopus 로고
    • A growth hormone antagonist protects mice against streptozotocin induced glomerulosclerosis even in the presence of elevated levels of glucose and glycated hemoglobin
    • Chen NY, Chen WY, Kopchick JJ: A growth hormone antagonist protects mice against streptozotocin induced glomerulosclerosis even in the presence of elevated levels of glucose and glycated hemoglobin. Endocrinology 1996;137:5163-5165.
    • (1996) Endocrinology , vol.137 , pp. 5163-5165
    • Chen, N.Y.1    Chen, W.Y.2    Kopchick, J.J.3
  • 36
    • 0033047377 scopus 로고    scopus 로고
    • Inhibitory effect of a growth hormone receptor antagonist (G120K-PEG) on renal enlargement, glomerular hypertrophy and urinary albumin excretion in experimental diabetes in mice
    • Flyvbjerg A, Bennet WF, Rasch R, Kopchick JJ, Scarlett JA: Inhibitory effect of a growth hormone receptor antagonist (G120K-PEG) on renal enlargement, glomerular hypertrophy and urinary albumin excretion in experimental diabetes in mice. Diabetes 1999;48:377-382.
    • (1999) Diabetes , vol.48 , pp. 377-382
    • Flyvbjerg, A.1    Bennet, W.F.2    Rasch, R.3    Kopchick, J.J.4    Scarlett, J.A.5
  • 37
    • 0035800512 scopus 로고    scopus 로고
    • Reduced mammary gland carcinogenesis in transgenic mice expressing a growth hormone antagonist
    • Pollak M, Blouin MJ, Zhang JC, Kopchick JJ: Reduced mammary gland carcinogenesis in transgenic mice expressing a growth hormone antagonist. Br J Cancer 2001;85:428-430.
    • (2001) Br J Cancer , vol.85 , pp. 428-430
    • Pollak, M.1    Blouin, M.J.2    Zhang, J.C.3    Kopchick, J.J.4
  • 39
    • 0034455827 scopus 로고    scopus 로고
    • Assessment of growth parameters and life span of GHR/BP gene-disrupted mice
    • Coschigano KT, Clemmons D, Bellush LL, Kopchick JJ: Assessment of growth parameters and life span of GHR/BP gene-disrupted mice. Endocrinology 2000;141:2608-2613.
    • (2000) Endocrinology , vol.141 , pp. 2608-2613
    • Coschigano, K.T.1    Clemmons, D.2    Bellush, L.L.3    Kopchick, J.J.4
  • 40
    • 0034082772 scopus 로고    scopus 로고
    • Conditional knockout of mouse insulin-like growth factor-1 gene using the Cre/loxP system
    • Liu JL, Yakar S, LeRoith D: Conditional knockout of mouse insulin-like growth factor-1 gene using the Cre/loxP system. Proc Soc Exp Biol Med 2000;223:344-351.
    • (2000) Proc Soc Exp Biol Med , vol.223 , pp. 344-351
    • Liu, J.L.1    Yakar, S.2    LeRoith, D.3
  • 43
    • 0025823103 scopus 로고
    • Dimerization of human growth hormone by zinc
    • Cunningham BC, Mulkerrin MG, Wells JA: Dimerization of human growth hormone by zinc. Science 1991;253:545-548.
    • (1991) Science , vol.253 , pp. 545-548
    • Cunningham, B.C.1    Mulkerrin, M.G.2    Wells, J.A.3
  • 44
    • 0037162458 scopus 로고    scopus 로고
    • Ligand-independent growth hormone receptor dimerization occurs in the endoplasmic reticulum and is required for ubiquitin system-dependent endocytosis
    • Gent J, van Kerkhof P, Roza M, Bu G, Strous GJ: Ligand-independent growth hormone receptor dimerization occurs in the endoplasmic reticulum and is required for ubiquitin system-dependent endocytosis. Proc Natl Acad Sci USA 2002;99:9858-9863.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 9858-9863
    • Gent, J.1    Van Kerkhof, P.2    Roza, M.3    Bu, G.4    Strous, G.J.5
  • 45
    • 0029989302 scopus 로고    scopus 로고
    • Growth hormone (GH) and a GH antagonist promote GH receptor dimerization and internalization
    • Harding PA, Wang X, Okada S, Chen WY, Wan W, Kopchick JJ: Growth hormone (GH) and a GH antagonist promote GH receptor dimerization and internalization. J Biol Chem 1996;271:6708-6712.
    • (1996) J Biol Chem , vol.271 , pp. 6708-6712
    • Harding, P.A.1    Wang, X.2    Okada, S.3    Chen, W.Y.4    Wan, W.5    Kopchick, J.J.6
  • 46
    • 0035040522 scopus 로고    scopus 로고
    • Binding and functional studies with the growth hormone receptor antagonist, B2036-PEG (pegvisomant), reveal effects of pegylation and evidence that it binds to a receptor dimer
    • Ross RJ, Leung KC, Maamra M, Bennett W, Doyle N, Waters MJ, Ho KK: Binding and functional studies with the growth hormone receptor antagonist, B2036-PEG (pegvisomant), reveal effects of pegylation and evidence that it binds to a receptor dimer. J Clin Endocrinol Metab 2001;86:1716-1723.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1716-1723
    • Ross, R.J.1    Leung, K.C.2    Maamra, M.3    Bennett, W.4    Doyle, N.5    Waters, M.J.6    Ho, K.K.7
  • 53
    • 0032509302 scopus 로고    scopus 로고
    • Genome sequence of the nematode C. elegans: A platform for investigating biology
    • The C. elegans Sequencing Consortium: Genome sequence of the nematode C. elegans: A platform for investigating biology. Science 1998;282:2012-2018.
    • (1998) Science , vol.282 , pp. 2012-2018
  • 55
    • 0034222259 scopus 로고    scopus 로고
    • The bioinformatics gold rush
    • Howard K: The bioinformatics gold rush. Sci Am 2000;283:58-63.
    • (2000) Sci Am , vol.283 , pp. 58-63
    • Howard, K.1
  • 56
    • 0035865397 scopus 로고    scopus 로고
    • Our genome unveiled
    • Baltimore D: Our genome unveiled. Nature 2001;409:814-816.
    • (2001) Nature , vol.409 , pp. 814-816
    • Baltimore, D.1
  • 58
    • 0035122576 scopus 로고    scopus 로고
    • Gene expression profile of the aging process in rat liver: Normalizing effects of growth hormone replacement
    • Tollet-Egnell P, Flores-Morales A, Stahlberg N, Malek RL, Lee N, Norstedt G: Gene expression profile of the aging process in rat liver: Normalizing effects of growth hormone replacement. Mol Endocrinol 2001;15:308-318.
    • (2001) Mol Endocrinol , vol.15 , pp. 308-318
    • Tollet-Egnell, P.1    Flores-Morales, A.2    Stahlberg, N.3    Malek, R.L.4    Lee, N.5    Norstedt, G.6
  • 60
    • 0034568794 scopus 로고    scopus 로고
    • Analysis of prolactin-modulated gene expression profiles during the Nb2 cell cycle using differential screening techniques
    • research 0008.0001-0008.0015
    • Bole-Feysot C, Perret E, Roustan P, Bouchard B, Kelly PA: Analysis of prolactin-modulated gene expression profiles during the Nb2 cell cycle using differential screening techniques. Genome Biol 2000;1:research 0008.0001-0008.0015.
    • (2000) Genome Biol , vol.1
    • Bole-Feysot, C.1    Perret, E.2    Roustan, P.3    Bouchard, B.4    Kelly, P.A.5
  • 61
    • 0034979625 scopus 로고    scopus 로고
    • Identification, isolation, and cloning of growth hormone (GH)-inducible interscapular brown adipose complementary deoxyribonucleic acid from GH antagonist mice
    • Li Y, Kelder B, Kopchick JJ: Identification, isolation, and cloning of growth hormone (GH)-inducible interscapular brown adipose complementary deoxyribonucleic acid from GH antagonist mice. Endocrinology 2001;142:2937-2945.
    • (2001) Endocrinology , vol.142 , pp. 2937-2945
    • Li, Y.1    Kelder, B.2    Kopchick, J.J.3
  • 62
    • 0028537612 scopus 로고
    • Growth patterns and body composition of transgenic mice expressing mutated bovine somatotropin genes
    • Knapp JR, Chen WY, Turner ND, Byers FM, Kopchick JJ: Growth patterns and body composition of transgenic mice expressing mutated bovine somatotropin genes. J Anim Sci 1994;72:2812-2819.
    • (1994) J Anim Sci , vol.72 , pp. 2812-2819
    • Knapp, J.R.1    Chen, W.Y.2    Turner, N.D.3    Byers, F.M.4    Kopchick, J.J.5
  • 63
    • 0035824501 scopus 로고    scopus 로고
    • Proteomics. High-speed biologists search for gold in proteins
    • Service RF: Proteomics. High-speed biologists search for gold in proteins. Science 2001;294:2074-2077.
    • (2001) Science , vol.294 , pp. 2074-2077
    • Service, R.F.1
  • 66
    • 0033518256 scopus 로고    scopus 로고
    • Synexpression groups in eukaryotes
    • Niehrs C, Pollet N: Synexpression groups in eukaryotes. Nature 1999;402:483-487.
    • (1999) Nature , vol.402 , pp. 483-487
    • Niehrs, C.1    Pollet, N.2


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