Mechanisms of conotoxin inhibition of N-type (Cav2.2) calcium channels

Biochimica et Biophysica Acta - Biomembranes

Volumn 1828, Issue 7, 2013, Pages 1619-1628

  Adams, David J ^a   Berecki, Géza ^a  

^a RMIT UNIVERSITY   (Australia)

Author keywords

Conotoxin; Conotoxin; GABAB receptor; N type calcium channel; Neuropathic pain; Nociceptor

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; ALPHA CONOTOXIN RGIA; ALPHA CONOTOXIN VC1.1; BACLOFEN; CALCIUM CHANNEL N TYPE; CAV2.2 CALCIUM CHANNEL; CONOTOXIN; FANATREX; G PROTEIN COUPLED RECEPTOR; GABAPENTIN; GABARONE; HYDROMORPHONE; MORPHINE; NARCOTIC ANALGESIC AGENT; NEOGAB; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; OMEGA CONOTOXIN; OMEGA CONOTOXIN CVID; OMEGA CONOTOXIN GVIA; OMEGA CONOTOXIN MVIIA; PREGABALIN; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

CALCIUM HOMEOSTASIS; CENTRAL NERVOUS SYSTEM DISEASE; CHRONIC PAIN; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG POTENTIATION; DRUG PROTEIN BINDING; DRUG SAFETY; DRUG SELECTIVITY; DRUG TOLERABILITY; EPILEPSY; HUMAN; HYPERALGESIA; INTRACELLULAR SIGNALING; LOW DRUG DOSE; NEUROPATHIC PAIN; NEUROTRANSMISSION; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REVIEW; SENSITIVITY ANALYSIS; SENSORY NERVE CELL; SENSORY SYSTEM ELECTROPHYSIOLOGY; SPINAL GANGLION; UNSPECIFIED SIDE EFFECT;

ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, N-TYPE; CONOTOXINS; HUMANS; MICE; PAIN;

GASTROPODA; MUS; RODENTIA;

EID: 84876932229     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2013.01.019     Document Type: Review

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