Discovery of diphenyl lactam derivatives as N-type calcium channel blockers

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 4, 2012, Pages 1716-1718

  Doherty, George A ^a   Bhatia, Pramila ^a   Vortherms, Timothy A ^a   Marsh, Kennan C ^a   Wetter, Jill M ^a   MacK, Helmut ^a   Scott, Victoria E ^a   Jarvis, Michael F ^a   Stewart, Andrew O ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

N type calcium channel blockers; Voltage gated calcium channels

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL N TYPE; CAPSAICIN; DIPHENYL LACTAM DERIVATIVE; GABAPENTIN; LACTAM DERIVATIVE; UNCLASSIFIED DRUG;

ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG EXPOSURE; DRUG STRUCTURE; HUMAN; HUMAN CELL; HYPERALGESIA; MICROSOME; NOCICEPTION; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

EID: 84856655494     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.12.100     Document Type: Article

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