Effects of intrathecal administration of ziconotide, a selective neuronal N-type calcium channel blocker, on mechanical allodynia and heat hyperalgesia in a rat model of postoperative pain

Pain

Volumn 84, Issue 2-3, 2000, Pages 151-158

  Wang, Yong Xiang ^a   Pettus, Mark ^a   Gao, Da ^a   Phillips, Cora ^a   Bowersox, S Scott ^a  

^a ELAN PHARMACEUTICALS   (United States)

Author keywords

Blocker; Ca2+ channels; Heat Hyperalgesia; Incisional pain; Mechanical allodynia; Morphine; Pain; Spinal Cord; Ziconotide

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CLONIDINE; MORPHINE; OMEGA CONOTOXIN MVIIA;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BOLUS INJECTION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; HEAT; HINDLIMB; HYPERALGESIA; INCISION; MALE; MECHANICAL STIMULATION; NONHUMAN; PAIN THRESHOLD; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RAT; SPINAL CORD; THERMAL STIMULATION;

ANALGESICS; ANALGESICS, OPIOID; ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, N-TYPE; CLONIDINE; HEAT; HYPERALGESIA; INJECTIONS, SPINAL; MALE; MORPHINE; NOCICEPTORS; OMEGA-CONOTOXINS; PAIN, POSTOPERATIVE; PHYSICAL STIMULATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0033963578     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(99)00197-9     Document Type: Article

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