Economic burden of chronic pain

Expert Review of Pharmacoeconomics and Outcomes Research

Volumn 6, Issue 5, 2006, Pages 591-601

  Phillips, Ceri J ^a  

^a SWANSEA UNIVERSITY   (United Kingdom)

Author keywords

Chronic pain; Cost; Economics; Effectiveness; Efficiency; Equity; Pain management; Quality of life

Indexed keywords

ANALGESIC AGENT; CYCLOOXYGENASE 2 INHIBITOR; NARCOTIC ANALGESIC AGENT; NON PRESCRIPTION DRUG; NONSTEROID ANTIINFLAMMATORY AGENT;

ARTHRITIS; ASTHMA; BACKACHE; CARDIOVASCULAR DISEASE; CHRONIC PAIN; CONGESTIVE HEART FAILURE; CONSTIPATION; COST BENEFIT ANALYSIS; COST EFFECTIVENESS ANALYSIS; COST OF ILLNESS; DEPRESSION; DIABETES MELLITUS; DRUG COST; DRUG EFFICACY; DRUG TOLERABILITY; DYSPEPSIA; EVIDENCE BASED MEDICINE; GASTROINTESTINAL TOXICITY; HEALTH CARE ACCESS; HEALTH CARE AVAILABILITY; HEALTH CARE COST; HEALTH CARE DELIVERY; HEALTH CARE UTILIZATION; HEALTH ECONOMICS; HOSPITAL ADMISSION; HOSPITAL COST; HUMAN; LIFESTYLE; MEDICAL DECISION MAKING; MIGRAINE; MUSCULOSKELETAL PAIN; NAUSEA; NECK PAIN; PAIN ASSESSMENT; PHYSIOTHERAPY; PRESCRIPTION; PREVALENCE; PRODUCTIVITY; PUBLIC HEALTH; QUALITY OF LIFE; RESOURCE ALLOCATION; REVIEW; RHEUMATOID ARTHRITIS; SHORT FORM 36; STOMACH DISEASE; STOMACH HEMORRHAGE; STOMACH PERFORATION; XEROSTOMIA;

EID: 33751006464     PISSN: 14737167     EISSN: 17448379     Source Type: Journal    
DOI: 10.1586/14737167.6.5.591     Document Type: Review

References (88)

1. Bruster S, Jarman B, Bosanquet N et al. National survey of hospital patients. Br. Med. J. 309, 1542-1546 (1994).
2. McQuay HJ, Moore RA, Justins D. Treating acute pain in hospital. Br. Med. J. 314, 1532-1535 (1997).
3. Audit Commission. Anaesthesia under examination. Audit Commission: London (1997).
4. Latham J, Davis BD. The socio-economic impact of chronic pain. Disabil. Rehabil. 16, 39-44 (1994).
5. Rudy TE, Kerns RD, Turk DC. Chronic pain and depression: toward a cognitive behavioural model. Pain 35, 129-140 (1988).
6. Merskey H, Bogduk N. Classification of Chronic Pain. International Association for the Study of Pain Press, Seattle, WA, USA 210 (1994).
7. International Association for the Study of Pain Subcommittee on Taxonomy. Classification of chronic pain. Descriptions of chronic pain syndromes and definitions of pain terms. Pain Suppl. 3, S1-S226 (1986).
8. Clark JD. Chronic pain prevalence and analgesic prescribing in a general medical population. J. Pain Symptom Manage. 23, 131-137 (2002).
9. Blyth FM, March LM, Brnabic AJ, Jorm LR, Williamson M, Cousins MJ. Chronic pain in Australia: a prevalence study. Pain 89, 127-134 (2001).
10. Verhaak PFM, Kerssens JJ, Dekker J et al. Prevalence of chronic benign pain disorder among adults: a review of the literature. Pain 77, 231-239 (2002).
11. Ospina M, Harstall C. Prevalence of Chronic Pain: an Overview. Alberta Heritage Foundation for Medical Research, Edmonton, Alberta, Canada. Report: HTA 29 (2002).
12. Breivik H, Collett B, Ventafridda V, Cohen R, Gallacher D. Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment. Eur. J. Pain 10, 287-333 (2006).
13. Crook J, Rideout E, Browne G. The prevalence of pain complaints in a general population. Pain 18, 299-314 (1984).
14. Van Korff M, Wagner EH, Dworkin SF et al. Chronic pain and use of ambulatory health care. Psychom. Med. 53, 61-79 (1991).
15. Elliott AM, Smith BH, Penny KI et al. The epidemiology of chronic pain in the community. Lancet 354, 1248-1252 (1999).
16. Elliott AM, Smith BH, Hannaford PC et al. The course of chronic pain in the community: results of a 4-year follow-up study. Pain 99, 299-307 (2002).
17. White KP, Harth M. The occurrence and impact of generalised pain. Ballieres Clin. Rheumatol. 13, 379-389 (1999).
18. Woolf AD, Pfleger B. Burden of major musculoskeletal conditions. Bull. World Health Organ. 81, 646-656 (2003).
19. Perquin C, Hazebroek-Kampscheur A, Hunfield J et al. Pain in children and adolescents: a common experience. Pain 87, 51-58 (2000).
20. Cousins MJ, Brennan F, Carr DB. Pain relief: a universal human right. Pain 112, 1-4 (2004).
21. Blyth FM, March LM, Brnabic AJM, Cousins MJ. Chronic pain and frequent use of health care. Pain 111, 51-58 (2004).
22. Drummond MF. Cost-of-illness studies: a major headache? Pharmacoeconomics 2, 1-4 (2004).
23. Koopmanschap MA, Rutten FFH, van Ineveld BM, van Roijen L. The friction cost method for measuring indirect costs of disease. J. Health Econ. 14, 171-89 (1995).
24. Borghouts JAJ, Koes BW, Vondeling H, Bouter LM. Cost-of-illness of neck pain in The Netherlands in 1996. Pain 80 (3), 629-636 (1999).
25. Maniadakis N, Gray A. The economic burden of back pain in the UK. Pain 84, 95-103 (2000).
26. Bolten W, Kempel-Waibel A, Pforringer W. Analysis of the cost of illness in backache. Med. Klin. 93, 388-393 (1998).
27. van Jaarsveld CHM, Jacobs JWG, Schrivers AJP et al. Direct cost of rheumatoid arthritis during the first six years: a cost-of-illness study. Br. J. Rheum. 37, 837-847 (1998).
28. Woolf AD, Zeidler H, Hagland U et al. Musculoskeletal pain in Europe: its impact and a comparison of population and medical perceptions of treatment in eight European countries. Ann. Rheum. Dis. 63, 342-347 (2004).
29. Walsh K, Cruddas M, Coggon D. Low back pain in eight areas of Britain. J. Epidemiol. Community Health 46, 227-230 (1993).
30. Belsey J. Primary care workload in the management of chronic pain: a retrospective cohort study using a GP database to identify resource implications for UK primary care. J. Med. Econ. 5, 39-52 (2002).
31. Eriksen J, Sjogren P, Bruera E, Ekholm O, Rasmussen NK. Critical issues on opioids in chronic non-cancer pain: an epidemiological study. Pain (2006) (Epub ahead of print).
32. Eriksen J, Sjogren P, Ekholm O, Rasmussen NK. Health care utilisation among individuals reporting long-term pain: an epidemiological study based on Danish National Health Surveys. Eur. J. Pain 8, 517-523 (1992).
33. Sleed M, Eccleston C, Beecham J, Knapp M, Jordan A. The economic impact of chronic pain in adolescence: methodological considerations and a preliminary cost-of-illness study. Pain 119, 183-190 (2004).
34. Fishman SM, Gallagher RM, Carr DB, Sullivan LW. The case for pain medicine. Pain Med. 5, 281-286 (2005).
35. Ekman M, Jonhagen S, Hunsche E, Jonsson L. Burden of illness of chronic back pain in Sweden: a cross-sectional, retrospective study in primary care setting. Spine 30, 1777-1785 (2005).
36. Eriksen J, Jensen MK, Sjogren P, Ekholm O, Rasmussen NK. Epidemiology of chronic non-malignant pain in Denmark. Pain 106, 221-228 (2003)
37. Eriksen J, Sjogren P. Epidemiological factors relating to long-term/ chronic non-cancer pain in Denmark. Ugeskr. Laeg. 168, 1947-1950 (2006).
38. Ricci JA, Stewart WF, Chee E, Leotta C, Foley K, Hochberg MC. Pain exacerbation as a major source of lost productive time in US workers with arthritis. Arthritis Rheum. 53, 673-681 (2005).
39. Frank AO, Chamberlain MA. Keeping our patients at work: implications for the management of those with rheumatoid arthritis and musculoskeletal conditions. Rheumatology 40, 1201-1205 (2001).
40. Autret-Leca E, Bertin P, Boulu P et al. La doleur aiguë de l'adulte en médicine générale. Enquête épidéiologique transversale nationale. Rev. Pract. 16, 648-652 (2001).
41. Burton WN, Conti DJ, Chen CY, Schultz AB, Edington DW. The role of health risk factors and disease on worker productivity. J. Occup. Environ. Med. 41, 863-877 (1999).
42. Allen H, Hubbard D, Sullivan S. The burden of pain on employee health and productivity at a major provider of business services. J. Occup. Environ. Med. 47, 658-670 (2005).
43. Stewart WF, Ricci JA, Chee E, Morganstein D, Lipton R. Lost productive time and cost due to common pain conditions in the US workforce. JAMA 290, 2443-2454 (2003).
44. Van Leeuwen MT, Blyth FM, March LM, Nicholas MK, Cousins MJ. Chronic pain and reduced work effectiveness: the hidden cost to Australian employers. Eur. J. Pain 10, 161-166 (2006).
45. Smith I. Cost considerations in the use of anaesthetic drugs. Pharmacoeconomics 19, 469-481 (2001).
46. Phillips CJ. The real cost of pain management. Anaesthesia 56, 1031-1033 (2001).
47. McQuay HJ, Moore RA. An Evidence Based Resource for Pain Relief. Oxford University Press, Oxford, UK (1998).
48. Gureje O, Von Korff M, Simon G et al. Persistent pain and well-being: a World Health Organization study in primary care. JAM4 280, 147-151 (1998).
49. Flor H, Turk DC, Scholz OB. Impact of chronic pain on the spouse: marital, emotional and physical consequences. J. Psychosom. Res. 31, 63-71 (1987).
50. Turk DC, Flor H, Rudy TE. Pain and families. I. Etiology, maintenance and psychological impact. Pain 30, 3-27 (1987).
51. Schwartz L, Slater MA, Birchler GR. The role of pain behaviors in the modulation of marital conflict in chronic pain couples. Pain 65, 227-233 (1996).
52. Schwartz L, Slater MA, Birchler GR et al. Depression in spouses of chronic pain patients: the role of patient pain and anger, and marital satisfaction. Pain 44, 61-67 (1991).
53. Kemler MA, Furnée CA. The impact of chronic pain on life in the household. J. Pain Symptom Manage. 23, 433-441 (2002).
54. Sprangers MA, de Regt EB, Andries F et al. Which chronic conditions are associated with a better or poorer quality of life? J. Clin. Epidemiol. 53, 895-897 (2000).
55. Kerr S, Fairbrother G, Crawford M, Hogg M, Fairbrother D, Khor KE. Patient characteristics and quality of life among a sample of Australian chronic pain clinic attendees. Int. Med. J. 34, 403-409 (2004).
56. Ellliott TE, Reiner CM, Palcher JA. Chronic pain, depression and quality of life: correlations and predictive value of the SF-36. Pain Med. 4, 331-339 (2003).
57. Reginster JY. The prevalence and burden of arthritis. Rheumatology 41(Suppl. 1), 3-6 (2001).
58. Becker N, Thomsens AB, Olsen AK et al. Pain epidemiology and health related quality of life in chronic non-malignant pain patients referred to a Danish multidisciplinary pain center. Pain 73, 393-400 (1997).
59. Williams AC. Outcome assessment in chronic non-cancer pain treatment. Acta Anaesthesiol. Scand. 45, 1076-1079 (2001).
60. Thomsen AB, Sørensen J, Sjøgren P et al. Economic evaluation of multidisciplinary pain management in chronic pain patients: a qualitative systematic review. J. Pain Symptom Manage. 22, 688-698 (2001).
61. Moore A, Edwards J, Barden J, McQuay H. Bandolier's Little Book of Pain. Oxford University Press, Oxford, UK (2003).
62. Evidence-Based Resource in Anaesthesia and Analgesia. Tramèr MR (Ed.). BMJ Books, London, UK (2003).
63. Campbell FA, Tramer MR, Carroll et al. Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review. Br. Med. J. 323, 1-6 (2001).
64. Buchbinder R, Jolley D, Wyatt M. Population based intervention to change back pain beliefs and disability: three part evaluation. Br. Med. J. 322, 1516-1520 (2001).
65. Guzmán J, Esmail R, Karjalainen K et al. Multidisciplinary rehabilitation for chronic low back pain: systematic review. Br. Med. J. 322, 1511-1516 (2001).
66. Loisel P, Lemaire J, Poitras S et al. Cost-benefit and cost-effectiveness analysis of a disability prevention model for back pain management: a six-year follow up study. Occup. Environ. Med. 59, 807-815 (2002).
67. Stadler M, Schlander M, Braeckman M, Nguyen T, Boogaerts JG. A cost-utility and cost-effectiveness analysis of an acute pain service. J. Clin. Anaesth. 16, 159-167 (2004).
68. UK Beam Trial Team. United Kingdom back pain exercise and manipulation (UK BEAM) randomised trial: effectiveness of phycial treatments for back pain in primary care. Br. Med. J. 329(7479), 1377 (2004).
69. Moore RA. Pain and systematic reviews. Acta Anaesthesiol. Scand. 45, 1136-1139 (2001).
70. Moore RA, McQuay HJ. Prevalence of opioid adverse events in chronic non-malignant pain: systematic review of randomised trials of oral opioids. Arthritis Res. Ther. 7, R1046-R1051 (2005).
71. Brooks P. Use and benefits of non-steroidal anti-inflammatory drugs. Am. J. Med. 104, S9-S13 (1998).
72. Blower AL, Brooks A, Fenn GC et al. Emergency admissions for upper gastrointestinal disease and their relation to NSAID use. Aliment. Pharmacol. Ther. 11, 283-291 (1997).
73. Tramer MR, Moore RA, Reynolds DJ et al. Quantitative estimation of rare adverse events which follow a biological progression: a new model applied to chronic NSAID use. Pain 85, 169-182 (2000).
74. Eccleston C, Yorke L, Morley S et al. Psychological therapies for the management of chronic and recurrent pain in children and adolescents. Cochrane Database Syst. Rev. (1), CD003968 (2003).
75. Karjalainen K, Malmivara A, van Tulder M et al. Multidisciplinary biopsychological rehabilitation for subacute low back pain among working age adults. Cochrane Database Syst. Rev. (2), CD002193 (2003).
76. Karjalainen K, Malmivara A, van Tulder M et al. Multidisciplinary biopsychological rehabilitation for neck and shoulder pain among working age adults. Cochrane Database Syst. Rev. (2), CD002194 (2003).
77. Phillips CJ. Health Economics: an Introduction for Healthcare Professionals. Blackwell Publishing, Qxford, UK (2005).
78. Moore RA, Phillips CJ. Cost of NSAID adverse effects to the UK National Health Service. J. Med. Econ. 2, 45-55 (1999).
79. Jonsson B, Haglund U. Economic burden of NSAID-induced gastropathy in Sweden. Scand. J. Gastroenterol. 36, 775-779 (2001).
80. Herings RM, Klungel OH. An epidemiological approach to assess the economic burden of NSAID-induced gastrointestinal events in The Netherlands. Pharmacoeconomics 19, 655-665 (2001).
81. Rahme E, Joseph L, Kong SX et al. Gastrointestinal health care resource use and costs asscoatied with nonsteroidal anti-inflammatory drugs versus acetaminophen: retrospective cohort study of an elderly population. Arthritis Rheum. 43, 917-924 (2000).
82. Page J, Henry D. Consumption of NSAIDs and the development of congestive heart failure in elderly patients: an under-recognized public health problem. Arch. Intern. Med. 160, 777-784 (2000).
83. Phillips CJ. And all because the doctor prescribed an NSAID: expenditure on PPIs and joined-up thinking in prescribing. Br. J. Health Care Manag. 8, 272-275 (2002).
84. Loeser JD. Economic implications of pain management. Acta Anaesthesiol. Scand. 43, 957-959 (1999).
85. Rawal N, Allvin R. Acute pain services in Europe: a 17-nation survey of 105 hospitals. The EuroPain Acute Pain Working Party. Eur. J. Anaesthesiol. 15, 354-363 (1998).
86. McQuay HJ, Moore RA, Eccleston C et al. Systematic review of outpatient services for chronic pain control. Health Technol. Assess. 1(6) 1-135 (1997).
87. Hopton JL, Dlugolecka M. Patients perceptions of need for primary health care services: useful for priority setting? Br. Med. J. 310, 1237-1240 (1995).
88. Loeser JD, Melzack R. Pain: an overview. Lancet 353, 1607-1609 (1999).