Alpha9 nicotinic acetylcholine receptors and the treatment of pain

Biochemical Pharmacology

Volumn 78, Issue 7, 2009, Pages 693-702

  McIntosh, J Michael ^a,b   Absalom, Nathan ^c   Chebib, Mary ^c   Elgoyhen, Ana Belén ^d,e   Vincler, Michelle ^f  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c UNIVERSITY OF SYDNEY   (Australia)

^d INSTITUTO DE INVESTIGACIONES EN INGENIERÍA GENÉTICA Y BIOLOGÍA MOLECULAR   (Argentina)

^e UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^f WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

Author keywords

Conotoxin Vc1.1; Contoxin RgIA; Alpha9 nicotinic; GABA B; Pain

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR STIMULATING AGENT; ALPHA CONOTOXIN; ALPHA CONOTOXIN PEIA; ALPHA CONOTOXIN RGIA; ALPHA CONOTOXIN VC1.1; BACLOFEN; CALCIUM CHANNEL N TYPE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA10; NICOTINIC RECEPTOR ALPHA9; NICOTINIC RECEPTOR ALPHA9ALPHA10; NICOTINIC RECEPTOR ALPHA9ALPHA10 BLOCKING AGENT; NICOTINIC RECEPTOR BLOCKING AGENT; OMEGA CONOTOXIN MVIIA; UNCLASSIFIED DRUG;

ABSENCE OF SIDE EFFECTS; ALLODYNIA; ANALGESIC ACTIVITY; ANTINOCICEPTION; ASTHENIA; CENTRAL NERVOUS SYSTEM DISEASE; CHRONIC PAIN; CLINICAL TRIAL; CONFUSION; DIABETIC NEUROPATHY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SAFETY; DRUG SELECTIVITY; DRUG TOLERANCE; HUMAN; HYPERALGESIA; IMMUNE RESPONSE; MULTIPLE DRUG DOSE; NERVE FUNCTION; NERVE INJURY; NEUROPATHIC PAIN; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; REPEATED DRUG DOSE; REVIEW; SEDATION; SIDE EFFECT; SINGLE DRUG DOSE;

ANALGESICS; ANIMALS; CONOTOXINS; HUMANS; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; PAIN; PROTEIN MULTIMERIZATION; PROTEIN SUBUNITS; RECEPTORS, GABA-B; RECEPTORS, NICOTINIC; RECOMBINANT PROTEINS;

EID: 68349131740     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.05.020     Document Type: Review

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